cardiovascularКардиоваскулярная терапия и профилактикаCardiovascular Therapy and Prevention1728-88002619-0125«SILICEA-POLIGRAF» LLCcardiovascular-1002Research ArticleИШЕМИЧЕСКАЯ БОЛЕЗНЬ СЕРДЦАCORONARY HEART DISEASEВозможности топической диагностики поражения коронарного русла у больных ишемической болезнью сердца при помощи контрастной стресс-эхокардиографии с дипиридамоломTopic diagnostics of coronary pathology in coronary heart disease patients by contrast stress echocardiography with dipyridamoleМацкеплишвилиС. Т.MatskeplishviliS. T.АсымбековаЭ. У.AsymbekovaE. U.АязянЭ. А.AyazyanE. A.ГулямоваД. Д.IoshinaV. I.КавтиашвилиТ. В.KavtiashviliT. V.Научный центр сердечно-сосудистой хирургии им. А.Н.Бакулева РАМН, МоскваA.N. Bakoulev Research Center for Cardiovascular Surgery, Russian Academy of Medical Science, Moscow200520102005453743Copyright © Мацкеплишвили С.Т., Асымбекова Э.У., Аязян Э.А., Гулямова Д.Д., Кавтиашвили Т.В., 20052005Мацкеплишвили С.Т., Асымбекова Э.У., Аязян Э.А., Гулямова Д.Д., Кавтиашвили Т.В.Matskeplishvili S.T., Asymbekova E.U., Ayazyan E.A., Ioshina V.I., Kavtiashvili T.V.Данная работа распространяется под лицензией Creative Commons Attribution 4.0.This work is licensed under a Creative Commons Attribution 4.0 License.https://cardiovascular.elpub.ru/jour/article/view/1002

Цель. Исследование посвящено определению диагностических возможностей контрастной стресс-эхокардиографии (КС-ЭхоКГ) с дипиридамолом у больных ишемической болезнью сердца (ИБС). Материал и методы. Обследованы 22 пациента с типичными клиническими проявлениями стенокардии, средний возраст 56,04±1,8 лет. В сравнительном аспекте рассматриваются результаты традиционной стресс-ЭхоКГ (С-ЭхоКГ) с дипиридамолом и КС-ЭхоКГ по отношению к данным коронароангиографии (КАГ). Результаты. Продемонстрировано, что оба метода ЭхоКГ визуализации высокоинформативны в плане топической диагностики коронарного атеросклероза – 91% по отношению к результатам КАГ. Выполнение КС-ЭхоКГ имеет ряд существенных преимуществ. Чувствительность, специфичность и диагностическая ценность КС-ЭхоКГ по сравнению с традиционной С-ЭхоКГ составляют 95% и 75%, 95% и 86%, 50% и 91%, соответственно. В отличие от стандартной С-ЭхоКГ с дипиридамолом при КС-ЭхоКГ важное значение имеет факт появления нарушений перфузии на малых дозах дипиридамола, что позволяет визуализировать угнетение коронарного кровообращения раньше, чем могут появиться зоны асинергии. Заключение. КС-ЭхоКГ с дипиридамолом обладает высокой диагностической ценностью в определении коронарной недостаточности с различной степенью поражения коронарного русла. Результаты КСЭхоКГ с дипиридамолом сопоставимы с результатами КАГ.

Aim. To assess diagnostic potential of contrast stress echocardiography (CS-EchoCG) with dipyridamole in coronary heart disease (CHD) patients. Material and methods. The study included 22 patients (mean age 56.04±1.8 years) with typical CHD clinics. The results of traditional S-EchoCG and CS-EchoCG with dipyridamole were compared with coronaroangiography (CAG) data. Results. Both methods of EchoCG visualization were highly informative for topic diagnostics of coronary atherosclerosis – 91%, comparing with CAG results. CS-EchoCG had a number of benefits: sensitivity, specificity, and prognostic value, comparing to traditional S-EchoCG, were 95% and 75%, 95% and 86%, 50% and 91%, respectively. In CS-EchoCG, perfusion abnormalities were registered even with low dipyridamole doses. This allows to diagnose coronary blood flow disturbance before asynergic zones appear. Conclusion. CS-EchoCG with dipyridamole was highly predictive in coronary insufficiency diagnostics. The results of CS-EchoCG and CAG were comparable.

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The authors declare that there are no conflicts of interest present.