<?xml version="1.0" encoding="UTF-8"?>
<!DOCTYPE article PUBLIC "-//NLM//DTD JATS (Z39.96) Journal Publishing DTD v1.3 20210610//EN" "JATS-journalpublishing1-3.dtd">
<article article-type="research-article" dtd-version="1.3" xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink" xmlns:xsi="http://www.w3.org/2001/XMLSchema-instance" xml:lang="ru"><front><journal-meta><journal-id journal-id-type="publisher-id">cardiovascular</journal-id><journal-title-group><journal-title xml:lang="ru">Кардиоваскулярная терапия и профилактика</journal-title><trans-title-group xml:lang="en"><trans-title>Cardiovascular Therapy and Prevention</trans-title></trans-title-group></journal-title-group><issn pub-type="ppub">1728-8800</issn><issn pub-type="epub">2619-0125</issn><publisher><publisher-name>«SILICEA-POLIGRAF» LLC</publisher-name></publisher></journal-meta><article-meta><article-id custom-type="elpub" pub-id-type="custom">cardiovascular-1065</article-id><article-categories><subj-group subj-group-type="heading"><subject>Research Article</subject></subj-group><subj-group subj-group-type="section-heading" xml:lang="ru"><subject>ЭПИДЕМИОЛОГИЯ И ПРОФИЛАКТИКА</subject></subj-group><subj-group subj-group-type="section-heading" xml:lang="en"><subject>EPIDEMIOLOGY AND PREVENTION</subject></subj-group></article-categories><title-group><article-title>Распространенность факторов риска сердечно-сосудистых заболеваний среди работников газовой промышленности: сравнение с результатами проекта MONICA и распределение уровней 10-летнего риска тяжелых коронарных осложнений у лиц без ишемической болезни сердца</article-title><trans-title-group xml:lang="en"><trans-title>Prevalence of cardiovascular risk factors in gas industry workers: comparison with MONICA Study results; 10-year risk distribution for severe coronary complications in coronary heart disease-free patients</trans-title></trans-title-group></title-group><contrib-group><contrib contrib-type="author" corresp="yes"><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Аксенов</surname><given-names>В. А.</given-names></name><name name-style="western" xml:lang="en"><surname>Aksenov</surname><given-names>V. A.</given-names></name></name-alternatives><email xlink:type="simple">V.Aksenov@ogp.ru</email><xref ref-type="aff" rid="aff-1"/></contrib><contrib contrib-type="author" corresp="yes"><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Тиньков</surname><given-names>А. Н.</given-names></name><name name-style="western" xml:lang="en"><surname>Tin’kov</surname><given-names>A. N.</given-names></name></name-alternatives><xref ref-type="aff" rid="aff-1"/></contrib></contrib-group><aff-alternatives id="aff-1"><aff xml:lang="ru"><institution>Медицинская служба ООО «Оренбурггазпром». Оренбург, Россия</institution></aff><aff xml:lang="en"><institution>Medical Service, “Orenburggazprom Ltd.’. Orenburg</institution></aff></aff-alternatives><pub-date pub-type="collection"><year>2006</year></pub-date><pub-date pub-type="epub"><day>20</day><month>02</month><year>2006</year></pub-date><volume>5</volume><issue>1</issue><fpage>5</fpage><lpage>13</lpage><permissions><copyright-statement>Copyright &amp;#x00A9; Аксенов В.А., Тиньков А.Н., 2006</copyright-statement><copyright-year>2006</copyright-year><copyright-holder xml:lang="ru">Аксенов В.А., Тиньков А.Н.</copyright-holder><copyright-holder xml:lang="en">Aksenov V.A., Tin’kov A.N.</copyright-holder><license xml:lang="ru" license-type="creative-commons-attribution" xlink:href="https://creativecommons.org/licenses/by/4.0/" xlink:type="simple"><license-p>Данная работа распространяется под лицензией Creative Commons Attribution 4.0.</license-p></license><license xml:lang="en" license-type="creative-commons-attribution" xlink:href="https://creativecommons.org/licenses/by/4.0/" xlink:type="simple"><license-p>This work is licensed under a Creative Commons Attribution 4.0 License.</license-p></license></permissions><self-uri xlink:href="https://cardiovascular.elpub.ru/jour/article/view/1065">https://cardiovascular.elpub.ru/jour/article/view/1065</self-uri><abstract><p>Цель. Сравнить показатели, характеризующие факторы риска (ФР) сердечно-сосудистых заболеваний (ССЗ), среди работников газовой промышленности и других популяций РФ. Анализ распределения уровней 10-летнего риска тяжелых коронарных осложнений (ТКО) у лиц без ишемической болезни сердца. Материал и методы. Обследованы 1807 мужчин, работников газовой промышленности, средний возраст 47,05±6,12 лет. Регистрировались информация о курении, рост, вес, артериальное давление (АД), содержание общего холестерина (ОХС) и холестерина липопротеидов высокой плотности (ХС ЛВП). В качестве сравнения были использованы данные контрольных групп проекта MONICA в Москве и Новосибирске. Проведен анализ распределения 10-летнего риска ТКО. Результаты. Различия АД в группах проекта MONICA и у участников исследования были статистически незначимы. Средние значения ОХС у работников газовой промышленности во всех возрастных подгруппах были статистически значимо выше, чем у всех участников проекта MONICA в Москве и Новосибирске, а ХС ЛВП – ниже. Доля ХС ЛВП в ОХС была статистически значимо ниже во всех оренбургских возрастных подгруппах, чем у участников проекта MONICA в Москве и Новосибирске. Средние значения индекса массы тела и распространенность табакокурения среди работников ООО «Оренбурггазпром» были статистически значимо выше, чем у всех участников проекта MONICA в Москве. При сравнении с участниками проекта MONICA из Новосибирска статистически значимой разности в распространенности этого ФР не обнаружено. Анализ распределения уровней 10-летнего риска ТКО продемонстрировал повышение риска с увеличением возраста обследованных, а также негативные различия в распределении риска по сравнению с их распределением среди взрослого населения США по данным исследования NHANES III. Заключение. Высокая распространенность ФР ССЗ и повышенных уровней 10-летнего риска ТКО среди работников газовой промышленности указывает на необходимость интенсификации первичной профилактики ССЗ в отрасли с использованием дифференцированного подхода на основе 10-летнего риска ТКО.</p></abstract><trans-abstract xml:lang="en"><sec><title>Aim</title><p>Aim. To compare characteristics of cardiovascular disease (CVD) risk factors (RF) in gas industry workers and other Russian populations. To analyze 10-year risk distribution for severe coronary complications (SCC) in individuals without coronary heart disease (CHD) at baseline. Material and methods. In total, 1807 men were examined; mean age 47.05±6.12 years. Information on smoking status, height/weight, blood pressure (BP), total cholesterol (TCH), and high-density lipoprotein (HDL) CH was registered. For comparison aims, control groups from MONICA Project in Moscow and Novosibirsk were used. Ten-year SCC risk was analyzed. Results. BP difference between MONICA Project populations and present group were statistically non-significant. Mean TCH levels in gas industry workers of all age groups were significantly higher, and HDL-CH levels – lower than in Moscow and Novosibirsk MONICA Project participants. HDL-CH percentage in TCH was substantially higher in all Orenburg age sub-groups, comparing to Moscow and Novosibirsk MONICA Project participants. Mean body mass index and smoking prevalence in «Orenburggazprom Ltd.» employees were significantly higher than in all Moscow, but not Novosibirsk, MONICA Project participants. Ten-year SCC risk was increasing with age, demonstrating inverse correlation with similar distribution in American adults (NHANES III data). Conclusion. High prevalence of CVD RF and increased 10-year SCC risk levels in gas industry workers explain a need for more aggressive primary CVD prevention, differentiated by 10-year SCC risk.</p></sec><sec><title> </title><p> </p></sec></trans-abstract><kwd-group xml:lang="ru"><kwd>сердечно-сосудистые заболевания</kwd><kwd>первичная профилактика</kwd><kwd>факторы риска</kwd><kwd>10-летний риск тяжелых коронарных осложнений</kwd></kwd-group><kwd-group xml:lang="en"><kwd>Cardiovascular disease</kwd><kwd>primary prevention</kwd><kwd>risk factors</kwd><kwd>10-year risk of severe coronary complications</kwd></kwd-group></article-meta></front><back><ref-list><title>References</title><ref id="cit1"><label>1</label><citation-alternatives><mixed-citation xml:lang="ru">Биометрика. URL: http://www.biometrica.tomsk.ru/index.htm</mixed-citation><mixed-citation xml:lang="en">Биометрика. URL: http://www.biometrica.tomsk.ru/index.htm</mixed-citation></citation-alternatives></ref><ref id="cit2"><label>2</label><citation-alternatives><mixed-citation xml:lang="ru">Бритов А.Н., Елисеева Н.А., Деев А.Д. и дp. Изучение социально-экономических факторов в развитии сердечно-сосудистых заболеваний на примере скрининга 4 городов Московской области. РКЖ 2001; 5: 34-7.</mixed-citation><mixed-citation xml:lang="en">Бритов А.Н., Елисеева Н.А., Деев А.Д. и дp. Изучение социально-экономических факторов в развитии сердечно-сосудистых заболеваний на примере скрининга 4 городов Московской области. РКЖ 2001; 5: 34-7.</mixed-citation></citation-alternatives></ref><ref id="cit3"><label>3</label><citation-alternatives><mixed-citation xml:lang="ru">Второй пересмотр рекомендаций ВНОК по профилактике, диагностике и лечению артериальной гипертензии, Кардиоваск тер профил 2004; 6(приложение): 2-19.</mixed-citation><mixed-citation xml:lang="en">Второй пересмотр рекомендаций ВНОК по профилактике, диагностике и лечению артериальной гипертензии, Кардиоваск тер профил 2004; 6(приложение): 2-19.</mixed-citation></citation-alternatives></ref><ref id="cit4"><label>4</label><citation-alternatives><mixed-citation xml:lang="ru">Максимова Т.М. Современное состояние, тенденции и перспективные оценки здоровья населения. Москва «ПЕР СЭ» 2002.</mixed-citation><mixed-citation xml:lang="en">Максимова Т.М. Современное состояние, тенденции и перспективные оценки здоровья населения. Москва «ПЕР СЭ» 2002.</mixed-citation></citation-alternatives></ref><ref id="cit5"><label>5</label><citation-alternatives><mixed-citation xml:lang="ru">2003 European Society of Hypertension–European Society of Cardiology guidelines for the management of arterial hypertension. J Hypertens 2003; 21(6): 1011-53.</mixed-citation><mixed-citation xml:lang="en">2003 European Society of Hypertension–European Society of Cardiology guidelines for the management of arterial hypertension. J Hypertens 2003; 21(6): 1011-53.</mixed-citation></citation-alternatives></ref><ref id="cit6"><label>6</label><citation-alternatives><mixed-citation xml:lang="ru">Cappuccio P, Oakeshott P, Strazzullo P, Kerry S. Application of Framingham risk estimates to ethnic minorities in United Kingdom and implications for primary prevention of heart disease in general practice: cross sectional population based study. BMJ 2002; 325: 1271-6.</mixed-citation><mixed-citation xml:lang="en">Cappuccio P, Oakeshott P, Strazzullo P, Kerry S. Application of Framingham risk estimates to ethnic minorities in United Kingdom and implications for primary prevention of heart disease in general practice: cross sectional population based study. BMJ 2002; 325: 1271-6.</mixed-citation></citation-alternatives></ref><ref id="cit7"><label>7</label><citation-alternatives><mixed-citation xml:lang="ru">D’Agostino RB, Grundy S, Sullivan LM, Wilson P. Validation of the Framinham coronary heart disease prediction scores: results of a multiple ethnic groups investigation. JAMA 2001; 286: 180-7.</mixed-citation><mixed-citation xml:lang="en">D’Agostino RB, Grundy S, Sullivan LM, Wilson P. Validation of the Framinham coronary heart disease prediction scores: results of a multiple ethnic groups investigation. JAMA 2001; 286: 180-7.</mixed-citation></citation-alternatives></ref><ref id="cit8"><label>8</label><citation-alternatives><mixed-citation xml:lang="ru">European guidelines on cardiovascular disease prevention in clinical practice. Eur J Cardiovasc Prev Rehabil 2003;10(Suppl 1): S1-78.</mixed-citation><mixed-citation xml:lang="en">European guidelines on cardiovascular disease prevention in clinical practice. Eur J Cardiovasc Prev Rehabil 2003;10(Suppl 1): S1-78.</mixed-citation></citation-alternatives></ref><ref id="cit9"><label>9</label><citation-alternatives><mixed-citation xml:lang="ru">Expert Panel on Detection, Evaluation, and Treatment of High Blood Cholesterol in Adults: Executive summary of the third report of the National Cholesterol Education Program (NCEP) Expert Panel on Detection, Evaluation, and Treatment of High Blood Cholesterol in Adults (ATP III). JAMA 2001; 285: 2486-97.</mixed-citation><mixed-citation xml:lang="en">Expert Panel on Detection, Evaluation, and Treatment of High Blood Cholesterol in Adults: Executive summary of the third report of the National Cholesterol Education Program (NCEP) Expert Panel on Detection, Evaluation, and Treatment of High Blood Cholesterol in Adults (ATP III). JAMA 2001; 285: 2486-97.</mixed-citation></citation-alternatives></ref><ref id="cit10"><label>10</label><citation-alternatives><mixed-citation xml:lang="ru">Ford ES, Giles WH, Mokdad AH. The distribution of 10-Year risk for coronary heart disease among US adults: findings from the National Health and Nutrition Examination Survey III. JACC 2004; 43: 1791- 6.</mixed-citation><mixed-citation xml:lang="en">Ford ES, Giles WH, Mokdad AH. The distribution of 10-Year risk for coronary heart disease among US adults: findings from the National Health and Nutrition Examination Survey III. JACC 2004; 43: 1791- 6.</mixed-citation></citation-alternatives></ref><ref id="cit11"><label>11</label><citation-alternatives><mixed-citation xml:lang="ru">Galobardes В, Costanza MC, Bernstein MS, et al. Trends in risk factors for lifestyle-related diseases by socioeconomic position in Geneva, Switzerland, 1993—2000: health inequalities persist. Am J Pub Health 2003; 93(8): 1302-9.</mixed-citation><mixed-citation xml:lang="en">Galobardes В, Costanza MC, Bernstein MS, et al. Trends in risk factors for lifestyle-related diseases by socioeconomic position in Geneva, Switzerland, 1993—2000: health inequalities persist. Am J Pub Health 2003; 93(8): 1302-9.</mixed-citation></citation-alternatives></ref><ref id="cit12"><label>12</label><citation-alternatives><mixed-citation xml:lang="ru">Haseeb Ahmad Khan A Visual Basic Software for Computing Fisher’s Exact Probability. J Statist Softw 2003; 8(21): 1-7.</mixed-citation><mixed-citation xml:lang="en">Haseeb Ahmad Khan A Visual Basic Software for Computing Fisher’s Exact Probability. J Statist Softw 2003; 8(21): 1-7.</mixed-citation></citation-alternatives></ref><ref id="cit13"><label>13</label><citation-alternatives><mixed-citation xml:lang="ru">Jackson R. Updated New Zealand cardiovascular disease risk¬benefit prediction guide. BMJ 2000; 320: 709-10.</mixed-citation><mixed-citation xml:lang="en">Jackson R. Updated New Zealand cardiovascular disease risk¬benefit prediction guide. BMJ 2000; 320: 709-10.</mixed-citation></citation-alternatives></ref><ref id="cit14"><label>14</label><citation-alternatives><mixed-citation xml:lang="ru">Joint British recommendations on prevention of coronary heart disease in clinical practice. Heart 1998; 80(Suppl 2): S1-29.</mixed-citation><mixed-citation xml:lang="en">Joint British recommendations on prevention of coronary heart disease in clinical practice. Heart 1998; 80(Suppl 2): S1-29.</mixed-citation></citation-alternatives></ref><ref id="cit15"><label>15</label><citation-alternatives><mixed-citation xml:lang="ru">Leon DA, Shkolnikov VM. Social stress and the Russian mortality crisis. JAMA 1998; 279: 790-1.</mixed-citation><mixed-citation xml:lang="en">Leon DA, Shkolnikov VM. Social stress and the Russian mortality crisis. JAMA 1998; 279: 790-1.</mixed-citation></citation-alternatives></ref><ref id="cit16"><label>16</label><citation-alternatives><mixed-citation xml:lang="ru">Levintova M, Novotny T. Noncommunicable disease mortality in the Russian Federation: from legislation to policy. Bulletin of the WHO November 2004; 82(11): 875-80.</mixed-citation><mixed-citation xml:lang="en">Levintova M, Novotny T. Noncommunicable disease mortality in the Russian Federation: from legislation to policy. Bulletin of the WHO November 2004; 82(11): 875-80.</mixed-citation></citation-alternatives></ref><ref id="cit17"><label>17</label><citation-alternatives><mixed-citation xml:lang="ru">Men T, Brennan P, Boffetta P, Zaridze D. Russian mortality trends for 1991-2001: analysis by cause and region. BMJ 2003; 327: 964-70.</mixed-citation><mixed-citation xml:lang="en">Men T, Brennan P, Boffetta P, Zaridze D. Russian mortality trends for 1991-2001: analysis by cause and region. BMJ 2003; 327: 964-70.</mixed-citation></citation-alternatives></ref><ref id="cit18"><label>18</label><citation-alternatives><mixed-citation xml:lang="ru">Murray CJ, Lopez AD, eds. The Global Burden of Disease: A Comprehensive Assessment of Mortality and Disability From Disease, Injuries and Risk Factors in 1990 and Projected to 2020. Cambridge, Mass: Harvard School of Health; 1996.</mixed-citation><mixed-citation xml:lang="en">Murray CJ, Lopez AD, eds. The Global Burden of Disease: A Comprehensive Assessment of Mortality and Disability From Disease, Injuries and Risk Factors in 1990 and Projected to 2020. Cambridge, Mass: Harvard School of Health; 1996.</mixed-citation></citation-alternatives></ref><ref id="cit19"><label>19</label><citation-alternatives><mixed-citation xml:lang="ru">Physical status: the use and interpretation of anthropometry: report of a WHO expert committee. WHO Tech Rep Ser 1995; 854: 1-452.</mixed-citation><mixed-citation xml:lang="en">Physical status: the use and interpretation of anthropometry: report of a WHO expert committee. WHO Tech Rep Ser 1995; 854: 1-452.</mixed-citation></citation-alternatives></ref><ref id="cit20"><label>20</label><citation-alternatives><mixed-citation xml:lang="ru">Plavinski S L, Plavinskaya S I, Klimov A N. Social factors and increase in mortality in Russia in the 1990s: prospective cohort study. BMJ 2003; 326: 1240-2.</mixed-citation><mixed-citation xml:lang="en">Plavinski S L, Plavinskaya S I, Klimov A N. Social factors and increase in mortality in Russia in the 1990s: prospective cohort study. BMJ 2003; 326: 1240-2.</mixed-citation></citation-alternatives></ref><ref id="cit21"><label>21</label><citation-alternatives><mixed-citation xml:lang="ru">Prevention of coronary heart disease in clinical practice. Recommendations of the Second Joint Task Force of European and other Societies† on Coronary Prevention. Eur Heart J 1998; 19: 1434-503.</mixed-citation><mixed-citation xml:lang="en">Prevention of coronary heart disease in clinical practice. Recommendations of the Second Joint Task Force of European and other Societies† on Coronary Prevention. Eur Heart J 1998; 19: 1434-503.</mixed-citation></citation-alternatives></ref><ref id="cit22"><label>22</label><citation-alternatives><mixed-citation xml:lang="ru">Ramachandran S, French JM, Vanderpump MP, et al. Using the Framingham model to predict heart disease in the United Kingdom: retrospective study. BMJ 2000; 320: 676-7.</mixed-citation><mixed-citation xml:lang="en">Ramachandran S, French JM, Vanderpump MP, et al. Using the Framingham model to predict heart disease in the United Kingdom: retrospective study. BMJ 2000; 320: 676-7.</mixed-citation></citation-alternatives></ref><ref id="cit23"><label>23</label><citation-alternatives><mixed-citation xml:lang="ru">Shkolnikov V, McKee M, Leon DA. Changes in life expectancy in Russia in the mid-1990s. Lancet 2001; 357: 917-21.</mixed-citation><mixed-citation xml:lang="en">Shkolnikov V, McKee M, Leon DA. Changes in life expectancy in Russia in the mid-1990s. Lancet 2001; 357: 917-21.</mixed-citation></citation-alternatives></ref><ref id="cit24"><label>24</label><citation-alternatives><mixed-citation xml:lang="ru">State-Specific Prevalence of Smoking Among Adults, and Politics and Attitudes About Secondhand Smoke-United States, 2000; Centers for Disease Control and Prevention Weekly Report, 2000; 50: 1101-6.</mixed-citation><mixed-citation xml:lang="en">State-Specific Prevalence of Smoking Among Adults, and Politics and Attitudes About Secondhand Smoke-United States, 2000; Centers for Disease Control and Prevention Weekly Report, 2000; 50: 1101-6.</mixed-citation></citation-alternatives></ref><ref id="cit25"><label>25</label><citation-alternatives><mixed-citation xml:lang="ru">Lam TH, Ho SY, Hedley AJ, et al. Leisure Time Physical Activity and Mortality in Hong Kong: Case-control Study of All Adult Deaths in 1998 Ann Epidemiol 2004; 14: 391-8.</mixed-citation><mixed-citation xml:lang="en">Lam TH, Ho SY, Hedley AJ, et al. Leisure Time Physical Activity and Mortality in Hong Kong: Case-control Study of All Adult Deaths in 1998 Ann Epidemiol 2004; 14: 391-8.</mixed-citation></citation-alternatives></ref><ref id="cit26"><label>26</label><citation-alternatives><mixed-citation xml:lang="ru">Lam TH, Ho SY, Hedley AJ, et al. Mortality and smoking in Hong Kong: case¬control study of all adult deaths in 1998. BMJ 2001; 323: 1-6.</mixed-citation><mixed-citation xml:lang="en">Lam TH, Ho SY, Hedley AJ, et al. Mortality and smoking in Hong Kong: case¬control study of all adult deaths in 1998. BMJ 2001; 323: 1-6.</mixed-citation></citation-alternatives></ref><ref id="cit27"><label>27</label><citation-alternatives><mixed-citation xml:lang="ru">The WHO MONICA Project URL: http://www.ktl.fi/publications/monica/index.html</mixed-citation><mixed-citation xml:lang="en">The WHO MONICA Project URL: http://www.ktl.fi/publications/monica/index.html</mixed-citation></citation-alternatives></ref><ref id="cit28"><label>28</label><citation-alternatives><mixed-citation xml:lang="ru">Wilson PWF, D’Agostino RB, Levy D, et al. Prediction of coronary heart disease using risk factor categories. Circulation 1998; 97: 1837-47.</mixed-citation><mixed-citation xml:lang="en">Wilson PWF, D’Agostino RB, Levy D, et al. Prediction of coronary heart disease using risk factor categories. Circulation 1998; 97: 1837-47.</mixed-citation></citation-alternatives></ref><ref id="cit29"><label>29</label><citation-alternatives><mixed-citation xml:lang="ru">World Health Organization. The World Health Report 2003— Shaping the Future. Geneva, Switzerland: WHO; 2003.</mixed-citation><mixed-citation xml:lang="en">World Health Organization. The World Health Report 2003— Shaping the Future. Geneva, Switzerland: WHO; 2003.</mixed-citation></citation-alternatives></ref><ref id="cit30"><label>30</label><citation-alternatives><mixed-citation xml:lang="ru">Yach D, Hawkes C, Gould C, Hofman K. The Global Burden of Chronic Diseases Overcoming Impediments to Prevention and Control. JAMA 2004; 291: 2616-22.</mixed-citation><mixed-citation xml:lang="en">Yach D, Hawkes C, Gould C, Hofman K. The Global Burden of Chronic Diseases Overcoming Impediments to Prevention and Control. JAMA 2004; 291: 2616-22.</mixed-citation></citation-alternatives></ref></ref-list><fn-group><fn fn-type="conflict"><p>The authors declare that there are no conflicts of interest present.</p></fn></fn-group></back></article>
