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<article article-type="research-article" dtd-version="1.3" xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink" xmlns:xsi="http://www.w3.org/2001/XMLSchema-instance" xml:lang="ru"><front><journal-meta><journal-id journal-id-type="publisher-id">cardiovascular</journal-id><journal-title-group><journal-title xml:lang="ru">Кардиоваскулярная терапия и профилактика</journal-title><trans-title-group xml:lang="en"><trans-title>Cardiovascular Therapy and Prevention</trans-title></trans-title-group></journal-title-group><issn pub-type="ppub">1728-8800</issn><issn pub-type="epub">2619-0125</issn><publisher><publisher-name>«SILICEA-POLIGRAF» LLC</publisher-name></publisher></journal-meta><article-meta><article-id custom-type="elpub" pub-id-type="custom">cardiovascular-1173</article-id><article-categories><subj-group subj-group-type="heading"><subject>Research Article</subject></subj-group><subj-group subj-group-type="section-heading" xml:lang="ru"><subject>ОБЗОРЫ</subject></subj-group><subj-group subj-group-type="section-heading" xml:lang="en"><subject>REVIEWS</subject></subj-group></article-categories><title-group><article-title>Ожирение и артериальная гипертензия. Часть II: особенности антигипертензивной терапии при ожирении</article-title><trans-title-group xml:lang="en"><trans-title>Obesity and arterial hypertension. Part II: features of antihypertensive therapy in obese patients</trans-title></trans-title-group></title-group><contrib-group><contrib contrib-type="author" corresp="yes"><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Недогода</surname><given-names>С. В.</given-names></name><name name-style="western" xml:lang="en"><surname>Nedogoda</surname><given-names>S. V.</given-names></name></name-alternatives><email xlink:type="simple">nedogodasv@rambler.ru</email><xref ref-type="aff" rid="aff-1"/></contrib><contrib contrib-type="author" corresp="yes"><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Барыкина</surname><given-names>И. Н.</given-names></name><name name-style="western" xml:lang="en"><surname>Barykina</surname><given-names>I. N.</given-names></name></name-alternatives><xref ref-type="aff" rid="aff-1"/></contrib><contrib contrib-type="author" corresp="yes"><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Чаляби</surname><given-names>Т. А.</given-names></name><name name-style="western" xml:lang="en"><surname>Chalyabi</surname><given-names>T. A.</given-names></name></name-alternatives><xref ref-type="aff" rid="aff-1"/></contrib><contrib contrib-type="author" corresp="yes"><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Бутрина</surname><given-names>Л. В.</given-names></name><name name-style="western" xml:lang="en"><surname>Butrina</surname><given-names>L. V.</given-names></name></name-alternatives><xref ref-type="aff" rid="aff-1"/></contrib><contrib contrib-type="author" corresp="yes"><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Брель</surname><given-names>У. А.</given-names></name><name name-style="western" xml:lang="en"><surname>Brel</surname><given-names>U. A.</given-names></name></name-alternatives><xref ref-type="aff" rid="aff-1"/></contrib><contrib contrib-type="author" corresp="yes"><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Мазина</surname><given-names>Г. В.</given-names></name><name name-style="western" xml:lang="en"><surname>Mazina</surname><given-names>G. V.</given-names></name></name-alternatives><xref ref-type="aff" rid="aff-1"/></contrib><contrib contrib-type="author" corresp="yes"><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Подольская</surname><given-names>Е. А.</given-names></name><name name-style="western" xml:lang="en"><surname>Podolskaya</surname><given-names>E. A.</given-names></name></name-alternatives><xref ref-type="aff" rid="aff-1"/></contrib></contrib-group><aff-alternatives id="aff-1"><aff xml:lang="ru"><institution>Волгоградский государственный медицинский университет</institution></aff><aff xml:lang="en"><institution>Vdgograd State Medical University</institution></aff></aff-alternatives><pub-date pub-type="collection"><year>2009</year></pub-date><pub-date pub-type="epub"><day>20</day><month>02</month><year>2009</year></pub-date><volume>8</volume><issue>1</issue><fpage>88</fpage><lpage>98</lpage><permissions><copyright-statement>Copyright &amp;#x00A9; Недогода С.В., Барыкина И.Н., Чаляби Т.А., Бутрина Л.В., Брель У.А., Мазина Г.В., Подольская Е.А., 2009</copyright-statement><copyright-year>2009</copyright-year><copyright-holder xml:lang="ru">Недогода С.В., Барыкина И.Н., Чаляби Т.А., Бутрина Л.В., Брель У.А., Мазина Г.В., Подольская Е.А.</copyright-holder><copyright-holder xml:lang="en">Nedogoda S.V., Barykina I.N., Chalyabi T.A., Butrina L.V., Brel U.A., Mazina G.V., Podolskaya E.A.</copyright-holder><license xml:lang="ru" license-type="creative-commons-attribution" xlink:href="https://creativecommons.org/licenses/by/4.0/" xlink:type="simple"><license-p>Данная работа распространяется под лицензией Creative Commons Attribution 4.0.</license-p></license><license xml:lang="en" license-type="creative-commons-attribution" xlink:href="https://creativecommons.org/licenses/by/4.0/" xlink:type="simple"><license-p>This work is licensed under a Creative Commons Attribution 4.0 License.</license-p></license></permissions><self-uri xlink:href="https://cardiovascular.elpub.ru/jour/article/view/1173">https://cardiovascular.elpub.ru/jour/article/view/1173</self-uri><abstract><p>Обзор посвящен особенностям антигипертензивной терапии (АГТ) при артериальной гипертензии на фоне ожирения. Особое внимание уделяется патогенезу повышения артериального давления при ожирении. Проведен анализ безопасности применения различных классов антигипертензивных препаратов у этой проблемной категории пациентов. Приведены данные о наиболее эффективных режимах АГТ на фоне назначения медикаментозных средств для снижения веса.</p></abstract><trans-abstract xml:lang="en"><p>The review is devoted to the features of antihypertensive therapy (AHT) in arterial hypertension combined with obesity. Pathogenesis of blood pressure increase in obesity is emphasised. The authors analyse the safety of various antihypertensive medication classes in these patients. The most effective AHT schemes to combine with weight-reducing medications are described.</p></trans-abstract><kwd-group xml:lang="ru"><kwd>ожирение</kwd><kwd>артериальная гипертензия</kwd><kwd>сибутрамин</kwd><kwd>антигипертензивные препараты</kwd></kwd-group><kwd-group xml:lang="en"><kwd>obesity</kwd><kwd>arterial hypertension</kwd><kwd>sibutramine antihypertensive medications</kwd></kwd-group></article-meta></front><back><ref-list><title>References</title><ref id="cit1"><label>1</label><citation-alternatives><mixed-citation xml:lang="ru">Assmaim G, Schulte Н. The Prospective Cardiovascular Munster Study (PROCAM): prevalence of hyperlipidemia in persons with hypertension and/or diabetes mellitus and the relationship to coronary artery disease. Am Heart J 1989; 1116:1713-24.</mixed-citation><mixed-citation xml:lang="en">Assmaim G, Schulte Н. 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