cardiovascularКардиоваскулярная терапия и профилактикаCardiovascular Therapy and Prevention1728-88002619-0125«SILICEA-POLIGRAF» LLCcardiovascular-1256Research ArticleМНЕНИЕ ПО ПРОБЛЕМЕOPINION ON A PROBLEMВыбор оптимальной комбинации нейрогуморальных модуляторов при хронической сердечной недостаточности: уроки исследования CHARM-AddedChoosing optimal combination of neuro-humoral modulators in chronic heart failure: CHARM-Added study lessonsЛопатинЮ. М.LopatinYu. M.lopatin@sprint-v.com.ruВолгоградский государственный медицинский университет, Волгоградский областной кардиологический центр, ВолгоградVolgograd State Medical University, Volgograd Region Cardiology Center, Volgograd200720062007637681Copyright © Лопатин Ю.М., 20072007Лопатин Ю.М.Lopatin Y.M.Данная работа распространяется под лицензией Creative Commons Attribution 4.0.This work is licensed under a Creative Commons Attribution 4.0 License.https://cardiovascular.elpub.ru/jour/article/view/1256

Статья посвящена выбору оптимальных доз и комбинаций нейрогуморальных модуляторов при систолической дисфункции левого желудочка и сердечной недостаточности. Проанализированы результаты исследований CHARM-Added, Val-HeFT, RALES, EPHESUS и их влияние на современные рекомендации по диагностике и лечению хронической сердечной недостаточности.

The article is focused on choosing optimal doses and combinations of neuro-humoral modulators in systolic left ventricular dysfunction and heart failure. The results of CHARM-Added, Val-HeFT, RALES, and EPHESUS studies are analyzed, as well as their effect on modern recommendations on chronic heart failure diagnostics and treatment.

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The authors declare that there are no conflicts of interest present.