cardiovascularКардиоваскулярная терапия и профилактикаCardiovascular Therapy and Prevention1728-88002619-0125«SILICEA-POLIGRAF» LLCcardiovascular-1397Research ArticleПЕРЕДОВАЯ СТАТЬЯEDITORIALМожет ли частота сердечных сокращений рассматриваться в качестве фактора риска сердечно-сосудистых заболеваний?Could heart rate be regarded as cardiovascular disease risk factor?МаколкинВ. И.MakolkinV. I.dvmak@mail.ruЗябревФ. Н.ZyabrevF. N.fedor-z@yandex.ruМосковская медицинская академия им. И.М.Сеченова. МоскваРоссияI.M. Sechenov Moscow Medical Academy. MoscowRussian Federation2006201220065659Copyright © Маколкин В.И., Зябрев Ф.Н., 20062006Маколкин В.И., Зябрев Ф.Н.Makolkin V.I., Zyabrev F.N.This work is licensed under a Creative Commons Attribution 4.0 License.https://cardiovascular.elpub.ru/jour/article/view/1397

Статья посвящена роли повышенной частоты сердечных сокращений в качестве предиктора сердечнососудистых заболеваний. Большое количество эпидемиологических исследований убедительно свидетельствуют о связи этого показателя с общей и сердечно-сосудистой смертностью. Приводится обоснование ритм-замедляющей терапии с помощью принципиально нового препарата – ивабрадина, изолированно влияющего на функцию синусного узла. Результаты клинических исследований свидетельствуют об антиангинальной активности ивабрадина, что создает большие перспективы для его применения при стабильных формах ишемической болезни сердца.

The article is devoted to the role of increased heart rate (HR) as cardiovascular disease predictor. Many epidemiological studies demonstrate the link between this parameter and total and cardiovascular mortality. The authors describe rhythm-decelerating therapy with a new medication – ivabradine, specifically affecting sinus node function. Pilot studies confirm its antianginal efficacy, pointing to its potential in stable coronary heart disease management.

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The authors declare that there are no conflicts of interest present.