cardiovascularКардиоваскулярная терапия и профилактикаCardiovascular Therapy and Prevention1728-88002619-0125«SILICEA-POLIGRAF» LLCcardiovascular-1486Research ArticleРАЗНОЕСтруктурно-функциональные характеристики здорового сердца и их взаимосвязи с вегетативной регуляцией сердечного ритмаStructural and functional characteristics of healthy heart and their interrelations with vegetative heart regulationХурсЕ. М.KhursE. M.

доцент кафедры внутренних болезней № 1

Екатеринбург, Факс: (343)369-62-32, Тел.: +7 912 241 86 52

lmk@olympus.ruПоддубнаяА. В.PoddubnayaA. V.

Екатеринбург

ГОУ ВПО Уральская государственная медицинская академия РосздраваUral State Medical Academy2011200220111018086Copyright © Хурс Е.М., Поддубная А.В., 20112011Хурс Е.М., Поддубная А.В.Khurs E.M., Poddubnaya A.V.Данная работа распространяется под лицензией Creative Commons Attribution 4.0.This work is licensed under a Creative Commons Attribution 4.0 License.https://cardiovascular.elpub.ru/jour/article/view/1486

Цель. Поиск комплексного подхода к оценке структурно-геометрических особенностей здорового сердца и его вегетативной регуляции, разработка нормативных значений количественных индексов ремоделирования левого желудочка (ЛЖ). Материал и методы. Исследованы 106 здоровых лиц в возрасте 33,15±10,26 года (47 мужчин, 59 женщин) без сердечно-сосудистой патологии. Всем пациентам проведена трансторакальная эхокардиография (ЭхоКГ) с расчетом индексов ремоделирования ЛЖ, исследование вариабельности ритма сердца при суточном мониторировании ЭКГ. Результаты. Предложена методика исследования процессов ремоделирования на основе ЭхоКГ, приводятся установленные нормативные показатели для индексов ремоделирования и их гендерные особенности. Установлен ряд гендерных отличий в структуре и геометрии ЛЖ и вегетативной регуляции работы сердца. Заключение. Результаты исследования предлагаются к использованию в работах по изучению адаптивного и дезадаптивного ремоделирования сердца и его вегетативной регуляции.

Aim

Aim. To outline the complex approach to the assessment of healthy heart structure, geometry, and vegetative regulation; to specify the normative criteria for quantitative indices of left ventricular (LV) remodelling.

Material and methods

Material and methods. The study included 106 healthy people, aged 33,15±10,26 years (47 men, 59 women), without cardiovascular disease. All participants underwent transthoracic echocardiography (EchoCG), with LV remodelling index calculation, and 24-hour ECG monitoring with heart rate variability assessment.

Results

Results. The methodology for EchoCG assessment of remodelling process was developed, and the gender-specific normative values for remodelling indices were identified. Gender differences in LV structure, geometry, and vegetative heart regulation were observed.

Conclusion

Conclusion. The results obtained could be used in further research on adaptive and pathological heart remodelling and vegetative heart regulation.

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The authors declare that there are no conflicts of interest present.