cardiovascularКардиоваскулярная терапия и профилактикаCardiovascular Therapy and Prevention1728-88002619-0125«SILICEA-POLIGRAF» LLCcardiovascular-1496Research ArticleОБЗОРЫ ЛИТЕРАТУРЫREVIEW ARTICLESАлгоритмы антитромбоцитарной терапии у женщинAnti-platelet therapy algorithms in womenТкачеваО. Н.TkachevaO. N.

руководитель терапевтического отделения

Москва, Тел.: +79852118523

tkacheva@rambler.ruКирсановаТ. В.KirsanovaT. V.

терапевт, нефролог отделения

Москва

ЛатышеваН. В.LatyshevaN. V.

научный сотрудник отделения

Москва

ФГУ Научный центр акушерства, гинекологии и перинатологии им. академика В.И.КулаковаV.I. Kulakov Research Centre for Obstetrics, Gynecology, and Perinatology201120022011101110119Copyright © Ткачева О.Н., Кирсанова Т.В., Латышева Н.В., 20112011Ткачева О.Н., Кирсанова Т.В., Латышева Н.В.Tkacheva O.N., Kirsanova T.V., Latysheva N.V.Данная работа распространяется под лицензией Creative Commons Attribution 4.0.This work is licensed under a Creative Commons Attribution 4.0 License.https://cardiovascular.elpub.ru/jour/article/view/1496

В обзоре обоснована разработка алгоритмов антитромбоцитарной терапии (АТТ) у женщин. Подробно рассмотрены специфические гендерные особенности гемостаза и патогенеза тромбозов. Выделены “женские” факторы риска развития тромботических осложнений: прием оральных контрацептивов, беременность и послеродовый период, менопауза и заместительная гормональная терапия. Подробно проанализировано значение АТТ в первичной и вторичной профилактике сердечно-сосудистых заболеваний у женщин. Выделены “особые” показания для назначения ацетилсалициловой кислоты: преэклампсия, антифосфолипидный синдром, мигрень.

The review is focussed on the evidence base for anti-platelet therapy (APT) algorithms in women. Gender-specific features of haemostasis and thrombosis pathogenesis are emphasized. The “female” risk factors for thrombotic events include oral contraceptive use, pregnancy and post-labour period, menopause, and hormone replacement therapy. The APT role in primary and secondary cardiovascular prevention among women is analyzed. The gender-specific indications for acetylsalicylic acid therapy include pre-eclampsia, antiphospholipid syndrome, and migraine.

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The authors declare that there are no conflicts of interest present.