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<article article-type="research-article" dtd-version="1.3" xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink" xmlns:xsi="http://www.w3.org/2001/XMLSchema-instance" xml:lang="ru"><front><journal-meta><journal-id journal-id-type="publisher-id">cardiovascular</journal-id><journal-title-group><journal-title xml:lang="ru">Кардиоваскулярная терапия и профилактика</journal-title><trans-title-group xml:lang="en"><trans-title>Cardiovascular Therapy and Prevention</trans-title></trans-title-group></journal-title-group><issn pub-type="ppub">1728-8800</issn><issn pub-type="epub">2619-0125</issn><publisher><publisher-name>«SILICEA-POLIGRAF» LLC</publisher-name></publisher></journal-meta><article-meta><article-id custom-type="elpub" pub-id-type="custom">cardiovascular-1505</article-id><article-categories><subj-group subj-group-type="heading"><subject>Research Article</subject></subj-group><subj-group subj-group-type="section-heading" xml:lang="ru"><subject>ОБЗОРЫ</subject></subj-group><subj-group subj-group-type="section-heading" xml:lang="en"><subject>REVIEWS</subject></subj-group></article-categories><title-group><article-title>Применение β-адреноблокаторов у больных ишемической болезнью сердца. Данные доказательной медицины</article-title><trans-title-group xml:lang="en"><trans-title>Beta-adrenoblockers in coronary heart disease patients. Evidencebased medicine data</trans-title></trans-title-group></title-group><contrib-group><contrib contrib-type="author" corresp="yes"><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Радзевич</surname><given-names>А. Э.</given-names></name><name name-style="western" xml:lang="en"><surname>Radzevich</surname><given-names>A. E.</given-names></name></name-alternatives><email xlink:type="simple">vp@esmar.dol.ru</email><xref ref-type="aff" rid="aff-1"/></contrib><contrib contrib-type="author" corresp="yes"><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Евдокимова</surname><given-names>А. Г.</given-names></name><name name-style="western" xml:lang="en"><surname>Evdokimova</surname><given-names>A. G.</given-names></name></name-alternatives><email xlink:type="simple">vp@esmar.dol.ru</email><xref ref-type="aff" rid="aff-1"/></contrib><contrib contrib-type="author" corresp="yes"><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Коняхин</surname><given-names>А. Ю.</given-names></name><name name-style="western" xml:lang="en"><surname>Konyakhin</surname><given-names>A. Yu.</given-names></name></name-alternatives><email xlink:type="simple">vp@esmar.dol.ru</email><xref ref-type="aff" rid="aff-1"/></contrib><contrib contrib-type="author" corresp="yes"><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Попов</surname><given-names>В. В.</given-names></name><name name-style="western" xml:lang="en"><surname>Popov</surname><given-names>V. V.</given-names></name></name-alternatives><email xlink:type="simple">vp@esmar.dol.ru</email><xref ref-type="aff" rid="aff-1"/></contrib></contrib-group><aff-alternatives id="aff-1"><aff xml:lang="ru"><institution>Московский государственный медико-стоматологический университет Росздрава; Центральная больница № 6 “ОАО” РЖД, Москва</institution></aff><aff xml:lang="en"><institution>Moscow State Medico-Stomatological University, State Federal Agency for Health and Social Development; Central Hospital No. 6, Russian Railways, Moscow</institution></aff></aff-alternatives><pub-date pub-type="collection"><year>2007</year></pub-date><pub-date pub-type="epub"><day>01</day><month>01</month><year>1970</year></pub-date><volume>7</volume><issue>7</issue><fpage>105</fpage><lpage>115</lpage><permissions><copyright-statement>Copyright &amp;#x00A9; Радзевич А.Э., Евдокимова А.Г., Коняхин А.Ю., Попов В.В., 1970</copyright-statement><copyright-year>1970</copyright-year><copyright-holder xml:lang="ru">Радзевич А.Э., Евдокимова А.Г., Коняхин А.Ю., Попов В.В.</copyright-holder><copyright-holder xml:lang="en">Radzevich A.E., Evdokimova A.G., Konyakhin A.Y., Popov V.V.</copyright-holder><license xml:lang="ru" license-type="creative-commons-attribution" xlink:href="https://creativecommons.org/licenses/by/4.0/" xlink:type="simple"><license-p>Данная работа распространяется под лицензией Creative Commons Attribution 4.0.</license-p></license><license xml:lang="en" license-type="creative-commons-attribution" xlink:href="https://creativecommons.org/licenses/by/4.0/" xlink:type="simple"><license-p>This work is licensed under a Creative Commons Attribution 4.0 License.</license-p></license></permissions><self-uri xlink:href="https://cardiovascular.elpub.ru/jour/article/view/1505">https://cardiovascular.elpub.ru/jour/article/view/1505</self-uri><abstract><p>Высокая эффективность и безопасность применения β-адреноблокаторов (β-АБ) у пациентов с ишемической болезнью сердца (ИБС) в настоящее время четко определены и продемонстрированы результатами большого количества клинических исследований. β-АБ эффективны и безопасны в случае правильного режима дозирования и учета противопоказаний. Показано, что β-АБ достоверно снижают общую смертность и частоту внезапной сердечной смерти у больных ИБС.</p></abstract><trans-abstract xml:lang="en"><p>High effectiveness and safety of beta-adrenoblockers (BB) in patients with coronary heart disease (CHD) have been proven by manifold clinical trials. BB are effective and safe, provided dose regimen is correct and contraindications are taken into account. BB significantly reduce total mortality and sudden cardiac death risk in CHD patients.</p></trans-abstract><kwd-group xml:lang="ru"><kwd>ишемическая болезнь сердца</kwd><kwd>внезапная сердечная смерть</kwd><kwd>β-адреноблокаторы</kwd></kwd-group><kwd-group xml:lang="en"><kwd>coronary heart disease</kwd><kwd>sudden cardiac death</kwd><kwd>beta-adrenoblockers</kwd></kwd-group></article-meta></front><back><ref-list><title>References</title><ref id="cit1"><label>1</label><citation-alternatives><mixed-citation xml:lang="ru">Агеев Ф.Т. Применение β-блокаторов после инфаркта миокарда. 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