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<article article-type="research-article" dtd-version="1.3" xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink" xmlns:xsi="http://www.w3.org/2001/XMLSchema-instance" xml:lang="ru"><front><journal-meta><journal-id journal-id-type="publisher-id">cardiovascular</journal-id><journal-title-group><journal-title xml:lang="ru">Кардиоваскулярная терапия и профилактика</journal-title><trans-title-group xml:lang="en"><trans-title>Cardiovascular Therapy and Prevention</trans-title></trans-title-group></journal-title-group><issn pub-type="ppub">1728-8800</issn><issn pub-type="epub">2619-0125</issn><publisher><publisher-name>«SILICEA-POLIGRAF» LLC</publisher-name></publisher></journal-meta><article-meta><article-id custom-type="elpub" pub-id-type="custom">cardiovascular-1516</article-id><article-categories><subj-group subj-group-type="heading"><subject>Research Article</subject></subj-group><subj-group subj-group-type="section-heading" xml:lang="ru"><subject>МНЕНИЕ ПО ПРОБЛЕМЕ</subject></subj-group><subj-group subj-group-type="section-heading" xml:lang="en"><subject>OPINION ON A PROBLEM</subject></subj-group></article-categories><title-group><article-title>Периооперативное применение Р-адреноблокаторов и риск сердечно-сосудистых осложнений: все ли вопросы решены?</article-title><trans-title-group xml:lang="en"><trans-title>Perioperative beta-adrenoblocker therapy and cardiovascular event risk: are all the problems solved?</trans-title></trans-title-group></title-group><contrib-group><contrib contrib-type="author" corresp="yes"><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Лопатин</surname><given-names>Ю. М.</given-names></name><name name-style="western" xml:lang="en"><surname>Lopatin</surname><given-names>Yu. M.</given-names></name></name-alternatives><bio xml:lang="ru"><p>Заведующий кафедрой кардиологии с функциональной диагностикой ФУВ; заведующий отделом ишемической болезни сердца</p></bio><email xlink:type="simple">lopatin@vlpost.ru</email><xref ref-type="aff" rid="aff-1"/></contrib></contrib-group><aff-alternatives id="aff-1"><aff xml:lang="ru"><institution>Волгоградский государственный медицинский университет; Волгоградский областной кардиологический центр</institution></aff><aff xml:lang="en"><institution>Volgograd State Medical University; Volgograd Region Cardiology Centre</institution></aff></aff-alternatives><pub-date pub-type="collection"><year>2009</year></pub-date><pub-date pub-type="epub"><day>20</day><month>12</month><year>2009</year></pub-date><volume>8</volume><issue>6</issue><fpage>71</fpage><lpage>76</lpage><permissions><copyright-statement>Copyright &amp;#x00A9; Лопатин Ю.М., 2009</copyright-statement><copyright-year>2009</copyright-year><copyright-holder xml:lang="ru">Лопатин Ю.М.</copyright-holder><copyright-holder xml:lang="en">Lopatin Y.M.</copyright-holder><license xml:lang="ru" license-type="creative-commons-attribution" xlink:href="https://creativecommons.org/licenses/by/4.0/" xlink:type="simple"><license-p>Данная работа распространяется под лицензией Creative Commons Attribution 4.0.</license-p></license><license xml:lang="en" license-type="creative-commons-attribution" xlink:href="https://creativecommons.org/licenses/by/4.0/" xlink:type="simple"><license-p>This work is licensed under a Creative Commons Attribution 4.0 License.</license-p></license></permissions><self-uri xlink:href="https://cardiovascular.elpub.ru/jour/article/view/1516">https://cardiovascular.elpub.ru/jour/article/view/1516</self-uri><abstract><p>Статья посвящена возможностям применения Р-адреноблокаторов в периоперационном периоде у больных с некардиальным хирургическим вмешательствам. Проанализированы результаты рандомизированных клинических испытаний POISE (2007) и DECREASE (1999-2009).</p></abstract><trans-abstract xml:lang="en"><p>The paper focuses on beta-blocker potential in perioperative period among the patients undergoing non-cardiac surgery. The results of two randomised clinical trials, POISE (2007) and DECREASE (1999-2009), are analysed.</p></trans-abstract><kwd-group xml:lang="ru"><kwd>некардиальные хирургические вмешательства</kwd><kwd>периоперационный период</kwd><kwd>Р-адреноблокаторы</kwd><kwd>бисопролол</kwd></kwd-group><kwd-group xml:lang="en"><kwd>non-cardiac surgery</kwd><kwd>perioperative period</kwd><kwd>beta-adrenoblockers</kwd><kwd>bisoprolol</kwd></kwd-group></article-meta></front><back><ref-list><title>References</title><ref id="cit1"><label>1</label><citation-alternatives><mixed-citation xml:lang="ru">POISE Study Group. Effects of extended-release metoprolol succinate in patients undergoing non-cardiac surgery (POISE trial): a randomized controlled trial. Lancet 2008; 371: 1839-47.</mixed-citation><mixed-citation xml:lang="en">POISE Study Group. Effects of extended-release metoprolol succinate in patients undergoing non-cardiac surgery (POISE trial): a randomized controlled trial. Lancet 2008; 371: 1839-47.</mixed-citation></citation-alternatives></ref><ref id="cit2"><label>2</label><citation-alternatives><mixed-citation xml:lang="ru">Fleisher LA, Beckman JA, Brown KA, et al. ACC/AHA 2007 Guidelines on Perioperative Cardiovascular Evaluation and Care for Noncardiac Surgery: A Report of the American College of Cardiology/American Heart Association Task Force on Practice Guidelines. Circulation 2007; 116: e418-99.</mixed-citation><mixed-citation xml:lang="en">Fleisher LA, Beckman JA, Brown KA, et al. ACC/AHA 2007 Guidelines on Perioperative Cardiovascular Evaluation and Care for Noncardiac Surgery: A Report of the American College of Cardiology/American Heart Association Task Force on Practice Guidelines. Circulation 2007; 116: e418-99.</mixed-citation></citation-alternatives></ref><ref id="cit3"><label>3</label><citation-alternatives><mixed-citation xml:lang="ru">Yang H, Raymer K, Butler R, et al. The effects of perioperative beta-blockade: results of the Metoprolol after Vascular Surgery (MaVS) study, a randomized controlled trial. Am Heart J 2006; 152: 983-90.</mixed-citation><mixed-citation xml:lang="en">Yang H, Raymer K, Butler R, et al. The effects of perioperative beta-blockade: results of the Metoprolol after Vascular Surgery (MaVS) study, a randomized controlled trial. Am Heart J 2006; 152: 983-90.</mixed-citation></citation-alternatives></ref><ref id="cit4"><label>4</label><citation-alternatives><mixed-citation xml:lang="ru">Juul AB, Wetterslev J, Gluud C, et al. Effect of perioperative beta blockade in patients with diabetes undergoingmajor non-cardiac surgery: randomised placebo controlled, blinded multicentre trial. Br Med J 2006; 332: 1482.</mixed-citation><mixed-citation xml:lang="en">Juul AB, Wetterslev J, Gluud C, et al. Effect of perioperative beta blockade in patients with diabetes undergoingmajor non-cardiac surgery: randomised placebo controlled, blinded multicentre trial. Br Med J 2006; 332: 1482.</mixed-citation></citation-alternatives></ref><ref id="cit5"><label>5</label><citation-alternatives><mixed-citation xml:lang="ru">Bangalore S, Wetterslev J, Pranesh Sh, et al. Perioperative p blockers in patients having non-cardiac surgery: a meta-analysis. Lancet 2008, D0I:10.1016/S0140-6736(08)61560-3.</mixed-citation><mixed-citation xml:lang="en">Bangalore S, Wetterslev J, Pranesh Sh, et al. Perioperative p blockers in patients having non-cardiac surgery: a meta-analysis. Lancet 2008, D0I:10.1016/S0140-6736(08)61560-3.</mixed-citation></citation-alternatives></ref><ref id="cit6"><label>6</label><citation-alternatives><mixed-citation xml:lang="ru">Poldermans D, Boersma E, Bax JJ, et al. The effect of bisoprolol on perioperative mortality and myocardial infarction in high-risk patients undergoing vascular surgery. Dutch Echocardiographic Cardiac Risk Evaluation Applying Stress Echocardiography Study Group. N Engl J Med 1999; 341: 1789-94.</mixed-citation><mixed-citation xml:lang="en">Poldermans D, Boersma E, Bax JJ, et al. The effect of bisoprolol on perioperative mortality and myocardial infarction in high-risk patients undergoing vascular surgery. Dutch Echocardiographic Cardiac Risk Evaluation Applying Stress Echocardiography Study Group. N Engl J Med 1999; 341: 1789-94.</mixed-citation></citation-alternatives></ref><ref id="cit7"><label>7</label><citation-alternatives><mixed-citation xml:lang="ru">Poldermans D, Boersma E, Bax JJ, et al., for the Dutch Echocardiographic Cardiac Risk Evaluation Applying Stress Echocardiography Study Group. Bisoprolol reduces cardiac death and myocardial infarction in high-risk patients as long as 2 years after successful major vascular surgery. Eur Heart J 2001; 22: 1353-8.</mixed-citation><mixed-citation xml:lang="en">Poldermans D, Boersma E, Bax JJ, et al., for the Dutch Echocardiographic Cardiac Risk Evaluation Applying Stress Echocardiography Study Group. Bisoprolol reduces cardiac death and myocardial infarction in high-risk patients as long as 2 years after successful major vascular surgery. Eur Heart J 2001; 22: 1353-8.</mixed-citation></citation-alternatives></ref><ref id="cit8"><label>8</label><citation-alternatives><mixed-citation xml:lang="ru">Poldermans D, Bax JJ, Schouten O, et al. for the Dutch Echocardiographic Cardiac Risk Evaluation Applying Stress Echo Study Group. Should Major Vascular Surgery Be Delayed Because of Preoperative Cardiac Testing in Intermediate-Risk Patients Receiving Beta-Blocker Therapy With Tight Heart Rate Control? JACC 2006; 48: 964-9.</mixed-citation><mixed-citation xml:lang="en">Poldermans D, Bax JJ, Schouten O, et al. for the Dutch Echocardiographic Cardiac Risk Evaluation Applying Stress Echo Study Group. Should Major Vascular Surgery Be Delayed Because of Preoperative Cardiac Testing in Intermediate-Risk Patients Receiving Beta-Blocker Therapy With Tight Heart Rate Control? JACC 2006; 48: 964-9.</mixed-citation></citation-alternatives></ref><ref id="cit9"><label>9</label><citation-alternatives><mixed-citation xml:lang="ru">Poldermans D, Schouten O, Benner R, et al. Fluvastatin XL Use Is Associated With Improved Cardiac Outcome After Major Vascular Surgery. Results From A Randomized Placebo Controlled Trial: Decrease III. Circulation 2008; 118: S792.</mixed-citation><mixed-citation xml:lang="en">Poldermans D, Schouten O, Benner R, et al. Fluvastatin XL Use Is Associated With Improved Cardiac Outcome After Major Vascular Surgery. Results From A Randomized Placebo Controlled Trial: Decrease III. Circulation 2008; 118: S792.</mixed-citation></citation-alternatives></ref><ref id="cit10"><label>10</label><citation-alternatives><mixed-citation xml:lang="ru">Dunkelgrun M, Boersma E, Schouten O, et al. for The Dutch Echocardiographic Cardiac Risk Evaluation Applying Stress Echocardiography Study Group Bisoprolol and Fluvastatin for the Reduction of Perioperative Cardiac Mortality and Myocardial Infarction in Intermediate-Risk Patients Undergoing Noncardiovascular Surgery. A Randomized Controlled Trial (DECREASE-IV). Ann Surg 2009; 249: 921-6.</mixed-citation><mixed-citation xml:lang="en">Dunkelgrun M, Boersma E, Schouten O, et al. for The Dutch Echocardiographic Cardiac Risk Evaluation Applying Stress Echocardiography Study Group Bisoprolol and Fluvastatin for the Reduction of Perioperative Cardiac Mortality and Myocardial Infarction in Intermediate-Risk Patients Undergoing Noncardiovascular Surgery. A Randomized Controlled Trial (DECREASE-IV). Ann Surg 2009; 249: 921-6.</mixed-citation></citation-alternatives></ref></ref-list><fn-group><fn fn-type="conflict"><p>The authors declare that there are no conflicts of interest present.</p></fn></fn-group></back></article>
