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<article article-type="research-article" dtd-version="1.3" xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink" xmlns:xsi="http://www.w3.org/2001/XMLSchema-instance" xml:lang="ru"><front><journal-meta><journal-id journal-id-type="publisher-id">cardiovascular</journal-id><journal-title-group><journal-title xml:lang="ru">Кардиоваскулярная терапия и профилактика</journal-title><trans-title-group xml:lang="en"><trans-title>Cardiovascular Therapy and Prevention</trans-title></trans-title-group></journal-title-group><issn pub-type="ppub">1728-8800</issn><issn pub-type="epub">2619-0125</issn><publisher><publisher-name>«SILICEA-POLIGRAF» LLC</publisher-name></publisher></journal-meta><article-meta><article-id custom-type="elpub" pub-id-type="custom">cardiovascular-1574</article-id><article-categories><subj-group subj-group-type="heading"><subject>Research Article</subject></subj-group><subj-group subj-group-type="section-heading" xml:lang="ru"><subject>ИШЕМИЧЕСКАЯ БОЛЕЗНЬ СЕРДЦА</subject></subj-group><subj-group subj-group-type="section-heading" xml:lang="en"><subject>CORONARY HEART DISEASE</subject></subj-group></article-categories><title-group><article-title>Особенности обратного ремоделирования сердца после коронарного шунтирования у больных ишемической болезнью сердца с Q-позитивным инфарктом миокарда в анамнезе</article-title><trans-title-group xml:lang="en"><trans-title>Reverse cardiac remodeling after coronary bypass surgery among coronary heart disease patients with Q-wave myocardial infarction in anamnesis</trans-title></trans-title-group></title-group><contrib-group><contrib contrib-type="author" corresp="yes"><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Тимофеева</surname><given-names>И. В.</given-names></name><name name-style="western" xml:lang="en"><surname>Timofeeva</surname><given-names>I. V.</given-names></name></name-alternatives><email xlink:type="simple">cardio-profi@narod.ru</email><xref ref-type="aff" rid="aff-1"/></contrib><contrib contrib-type="author" corresp="yes"><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Суханов</surname><given-names>С. Г.</given-names></name><name name-style="western" xml:lang="en"><surname>Sukhanov</surname><given-names>S. G.</given-names></name></name-alternatives><email xlink:type="simple">cardio-profi@narod.ru</email><xref ref-type="aff" rid="aff-1"/></contrib><contrib contrib-type="author" corresp="yes"><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Туев</surname><given-names>А. В.</given-names></name><name name-style="western" xml:lang="en"><surname>Tuev</surname><given-names>A. V.</given-names></name></name-alternatives><email xlink:type="simple">cardio-profi@narod.ru</email><xref ref-type="aff" rid="aff-1"/></contrib><contrib contrib-type="author" corresp="yes"><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Рямзина</surname><given-names>И. Н.</given-names></name><name name-style="western" xml:lang="en"><surname>Ryamzina</surname><given-names>I. N.</given-names></name></name-alternatives><email xlink:type="simple">cardio-profi@narod.ru</email><xref ref-type="aff" rid="aff-1"/></contrib></contrib-group><aff-alternatives id="aff-1"><aff xml:lang="ru"><institution>Филиал НЦССХ им. А.Н. Бакулева РАМН – Пермская областная клиническая больница №2 «Институт сердца». Пермь</institution></aff><aff xml:lang="en"><institution>A.N. Bakoulev Research Center for Cardiovascular Surgery Branch, Russian Academy of Medical Sciences – Perm’ Regional Clinical Hospital No. 2 «Heart Institute». Perm’</institution></aff></aff-alternatives><pub-date pub-type="collection"><year>2006</year></pub-date><pub-date pub-type="epub"><day>01</day><month>01</month><year>1970</year></pub-date><volume>5</volume><issue>7</issue><fpage>44</fpage><lpage>49</lpage><permissions><copyright-statement>Copyright &amp;#x00A9; Тимофеева И.В., Суханов С.Г., Туев А.В., Рямзина И.Н., 1970</copyright-statement><copyright-year>1970</copyright-year><copyright-holder xml:lang="ru">Тимофеева И.В., Суханов С.Г., Туев А.В., Рямзина И.Н.</copyright-holder><copyright-holder xml:lang="en">Timofeeva I.V., Sukhanov S.G., Tuev A.V., Ryamzina I.N.</copyright-holder><license xml:lang="ru" license-type="creative-commons-attribution" xlink:href="https://creativecommons.org/licenses/by/4.0/" xlink:type="simple"><license-p>Данная работа распространяется под лицензией Creative Commons Attribution 4.0.</license-p></license><license xml:lang="en" license-type="creative-commons-attribution" xlink:href="https://creativecommons.org/licenses/by/4.0/" xlink:type="simple"><license-p>This work is licensed under a Creative Commons Attribution 4.0 License.</license-p></license></permissions><self-uri xlink:href="https://cardiovascular.elpub.ru/jour/article/view/1574">https://cardiovascular.elpub.ru/jour/article/view/1574</self-uri><abstract><sec><title>Цель</title><p>Цель. Дать сравнительную оценку процессов обратного ремоделирования после коронарного шунтирования (КIII) у пациентов с ишемической болезнью сердца (ИБС) в зависимости от наличия в анамнезе инфаркта миокарда с зубцом Q (Q-ИМ). Материал и методы. В исследование включены 133 больных ИБС, подвергшихся КIII. Средний возраст пациентов - 56,03±8,90 лет. С учетом наличия Q-ИМ пациенты были разделены на 2 группы: I группа (n = 71) больные без ИМ в анамнезе (61,97%; n = 44) или с нe Q-ИМ (38,03%; n = 27), II группа (n = 62) пациенты с Q-ИМ в анамнезе. Всем больным выполняли эхокардиографическое исследование трижды: до оперативного лечения, в раннем (через 4,2±1,3 дня) и в отдаленном периоде, спустя 2,53±1,31 года после КШ. Результаты. Позитивные изменения структурно-функционального состояния сердца у больных ИБС после КIII происходят вне зависимости от наличия в анамнезе ИМ, однако степень их выраженности различна у пациентов с не Q-ИМ и с Q-ИМ в анамнезе. Достоверный прирост фракции выброса и снижение индекса нарушенной локальной сократимости в раннем периоде были зафиксированы в группе пациентов с крупноочаговым ИМ в анамнезе в связи с наличием большего количества зон с восстановленной локальной сократимостью. В отдаленном периоде наблюдения объемные показатели возвращаются к исходным, однако у пациентов с Q-ИМ в анамнезе сохраняется достоверное улучшение ФВ. Заключение. Позитивное влияние КIII на сократительную способность миокарда у больных Q-ИМ в анамнезе сохраняется в отдаленном послеоперационном периоде наблюдения.</p></sec><sec><title> </title><p> </p></sec></abstract><trans-abstract xml:lang="en"><p>Aim. To compare reverse remodeling process after coronary bypass surgery (CBS) in coronary heart disease (CHD) patients with and without Q-wave myocardial infarction (Q-IM) in anamnesis. Material and methods. The study included 133 CHD patients after CBS; mean age - 56,03±8,90 years. According to Q-IM presence, all participants were divided into two groups: Group I (n = 71) - patients without MI in anamnesis (61,97%; n = 44) or with non-Q-MI (38,03%; n = 27); Group II (n = 62) - patients with Q-MI in anamnesis. All participants underwent echocardiography for three times: before surgery; in early (4,2±1,3 days later) or longterm post-surgery period (2,53±1,31 years later). Results. Positive dynamics in cardiac structure and function among CHD patients after CBS was registered regardless of MI presence in anamnesis. Nevertheless, dynamics intensity differed in patients with non-Q-MI and Q-MI in anamnesis. Early significant increase in ejection fraction (EF) and decrease in abnormal local contractility index were observed in individuals with large infarction zones, due to multiple zones with restored local contractility. In long-term follow-up, volume parameters returned to baseline, but in patients with Q-MI, significant EF improvement persisted. Conclusion. Positive influence of CBS on myocardial contractility in patients with Q-MI in anamnesis persisted in long-term post-surgery period.</p></trans-abstract><kwd-group xml:lang="ru"><kwd>коронарное шунтирование</kwd><kwd>инфаркт миокарда с зубцом Q</kwd><kwd>ремоделирование сердца</kwd><kwd>эхокардиография</kwd></kwd-group><kwd-group xml:lang="en"><kwd>coronary bypass surgery</kwd><kwd>Q-wave myocardial infarction</kwd><kwd>cardiac remodeling</kwd><kwd>echocardiography</kwd></kwd-group></article-meta></front><back><ref-list><title>References</title><ref id="cit1"><label>1</label><citation-alternatives><mixed-citation xml:lang="ru">Сагг J.A., Haithcock B.E., Paone G., et al. Long-term outcome after coronary artery bypass grafting in patients with severe left ventricular dysfunction. Ann Thorac Surg 2002; 74(5): 1531-6.</mixed-citation><mixed-citation xml:lang="en">Сагг J.A., Haithcock B.E., Paone G., et al. 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