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<article article-type="research-article" dtd-version="1.3" xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink" xmlns:xsi="http://www.w3.org/2001/XMLSchema-instance" xml:lang="ru"><front><journal-meta><journal-id journal-id-type="publisher-id">cardiovascular</journal-id><journal-title-group><journal-title xml:lang="ru">Кардиоваскулярная терапия и профилактика</journal-title><trans-title-group xml:lang="en"><trans-title>Cardiovascular Therapy and Prevention</trans-title></trans-title-group></journal-title-group><issn pub-type="ppub">1728-8800</issn><issn pub-type="epub">2619-0125</issn><publisher><publisher-name>«SILICEA-POLIGRAF» LLC</publisher-name></publisher></journal-meta><article-meta><article-id custom-type="elpub" pub-id-type="custom">cardiovascular-1693</article-id><article-categories><subj-group subj-group-type="heading"><subject>Research Article</subject></subj-group><subj-group subj-group-type="section-heading" xml:lang="ru"><subject>ЭПИДЕМИОЛОГИЯ</subject></subj-group></article-categories><title-group><article-title>Биоритмологический подход к прогнозированию течения ишемической болезни сердца</article-title><trans-title-group xml:lang="en"><trans-title>Biorhythms in predicting coronary heart disease prognosis</trans-title></trans-title-group></title-group><contrib-group><contrib contrib-type="author" corresp="yes"><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Барбараш</surname><given-names>О. Л.</given-names></name><name name-style="western" xml:lang="en"><surname>Barbarash</surname><given-names>O. L.</given-names></name></name-alternatives><email xlink:type="simple">olb61@mail.ru</email><xref ref-type="aff" rid="aff-1"/></contrib><contrib contrib-type="author" corresp="yes"><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Фомина</surname><given-names>Н. В.</given-names></name><name name-style="western" xml:lang="en"><surname>Fomina</surname><given-names>N. V.</given-names></name></name-alternatives><email xlink:type="simple">olb61@mail.ru</email><xref ref-type="aff" rid="aff-1"/></contrib><contrib contrib-type="author" corresp="yes"><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Минеева</surname><given-names>Е. В.</given-names></name><name name-style="western" xml:lang="en"><surname>Mineeva</surname><given-names>E. V.</given-names></name></name-alternatives><email xlink:type="simple">olb61@mail.ru</email><xref ref-type="aff" rid="aff-2"/></contrib><contrib contrib-type="author" corresp="yes"><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Алтарев</surname><given-names>С. С.</given-names></name><name name-style="western" xml:lang="en"><surname>Altarev</surname><given-names>S. S.</given-names></name></name-alternatives><email xlink:type="simple">olb61@mail.ru</email><xref ref-type="aff" rid="aff-1"/></contrib><contrib contrib-type="author" corresp="yes"><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Чумакова</surname><given-names>Г. А.</given-names></name><name name-style="western" xml:lang="en"><surname>Chumakova</surname><given-names>G. A.</given-names></name></name-alternatives><email xlink:type="simple">olb6l@mail.ru</email><xref ref-type="aff" rid="aff-3"/></contrib><contrib contrib-type="author" corresp="yes"><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Сумин</surname><given-names>А. Н.</given-names></name><name name-style="western" xml:lang="en"><surname>Sumin</surname><given-names>A. N.</given-names></name></name-alternatives><email xlink:type="simple">olb6l@mail.ru</email><xref ref-type="aff" rid="aff-4"/></contrib><contrib contrib-type="author" corresp="yes"><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Тарасов</surname><given-names>Н. И.</given-names></name><name name-style="western" xml:lang="en"><surname>Tarasov</surname><given-names>N. I.</given-names></name></name-alternatives><email xlink:type="simple">olb6l@mail.ru</email><xref ref-type="aff" rid="aff-2"/></contrib><contrib contrib-type="author" corresp="yes"><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Кривоносов</surname><given-names>Д. С.</given-names></name><name name-style="western" xml:lang="en"><surname>Krivonosov</surname><given-names>D. S.</given-names></name></name-alternatives><email xlink:type="simple">olb6l@mail.ru</email><xref ref-type="aff" rid="aff-2"/></contrib><contrib contrib-type="author" corresp="yes"><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Барбараш</surname><given-names>Л. С.</given-names></name><name name-style="western" xml:lang="en"><surname>Barbarash</surname><given-names>L. S.</given-names></name></name-alternatives><email xlink:type="simple">olb6l@mail.ru</email><xref ref-type="aff" rid="aff-2"/></contrib></contrib-group><aff-alternatives id="aff-1"><aff xml:lang="ru"><institution>Кемеровская государственная медицинская академия, г. Кемерово</institution></aff><aff xml:lang="en"><institution>Kemerovo State Medical Academy. Kemerovo</institution></aff></aff-alternatives><aff-alternatives id="aff-2"><aff xml:lang="ru"><institution>Кемеровский кардиологический диспансер, г. Кемерово</institution></aff><aff xml:lang="en"><institution>Kemerovo Cardiology Dispanser. Kemerovo</institution></aff></aff-alternatives><aff-alternatives id="aff-3"><aff xml:lang="ru"><institution>Алтайский медицинский университет, г. Барнаул</institution></aff><aff xml:lang="en"><institution>Altay Medical University. Barnaul</institution></aff></aff-alternatives><aff-alternatives id="aff-4"><aff xml:lang="ru"><institution>Центр охраны здоровья шахтеров г. Ленинский-Кузнецкий. Кемеровская область</institution></aff><aff xml:lang="en"><institution>Miners' Health Center. Leninsky-Kuznetsky City, Kemerovo Region</institution></aff></aff-alternatives><pub-date pub-type="collection"><year>2008</year></pub-date><pub-date pub-type="epub"><day>20</day><month>12</month><year>2008</year></pub-date><volume>7</volume><issue>8</issue><fpage>4</fpage><lpage>11</lpage><permissions><copyright-statement>Copyright &amp;#x00A9; Барбараш О.Л., Фомина Н.В., Минеева Е.В., Алтарев С.С., Чумакова Г.А., Сумин А.Н., Тарасов Н.И., Кривоносов Д.С., Барбараш Л.С., 2008</copyright-statement><copyright-year>2008</copyright-year><copyright-holder xml:lang="ru">Барбараш О.Л., Фомина Н.В., Минеева Е.В., Алтарев С.С., Чумакова Г.А., Сумин А.Н., Тарасов Н.И., Кривоносов Д.С., Барбараш Л.С.</copyright-holder><copyright-holder xml:lang="en">Barbarash O.L., Fomina N.V., Mineeva E.V., Altarev S.S., Chumakova G.A., Sumin A.N., Tarasov N.I., Krivonosov D.S., Barbarash L.S.</copyright-holder><license xml:lang="ru" license-type="creative-commons-attribution" xlink:href="https://creativecommons.org/licenses/by/4.0/" xlink:type="simple"><license-p>Данная работа распространяется под лицензией Creative Commons Attribution 4.0.</license-p></license><license xml:lang="en" license-type="creative-commons-attribution" xlink:href="https://creativecommons.org/licenses/by/4.0/" xlink:type="simple"><license-p>This work is licensed under a Creative Commons Attribution 4.0 License.</license-p></license></permissions><self-uri xlink:href="https://cardiovascular.elpub.ru/jour/article/view/1693">https://cardiovascular.elpub.ru/jour/article/view/1693</self-uri><abstract><sec><title>Цель</title><p>Цель. Изучить 3-летнюю динамику зависимости частоты сердечно-сосудистых событий у пациентов с инфарктом миокарда (ИМ) от сезонов календарного и триместров индивидуального годичного цикла (ИГЦ).</p></sec><sec><title>Материал и методы</title><p>Материал и методы. В исследование включены 324 пациента на 5-7 сутки Q-ИМ с фракцией выброса левого желудочка ≤ 35 %. В течение 3-летнего периода наблюдения оценивались сердечно-сосудистые события: случаи смерти, усугубления сердечной недостаточности, повторного ИМ, эпизоды нестабильной стенокардии. На основании календарных данных о дате рождения больного был определен порядковый номер месяца ИГЦ, когда произошло любое неблагоприятное событие. В исследовании был учтен сезон года, в котором развилось сердечно-сосудистое событие.</p></sec><sec><title>Результаты</title><p>Результаты. Зимний и летний периоды года являются неблагоприятными в отношении вероятности развития сердечно-сосудистых событий, частоты госпитализаций и летальных исходов; наиболее благоприятным сезоном года является осень. Пик частоты развития коронарных событий и летальных исходов приходится на время вокруг дня рождения, т. е. I и IV триместры ИГЦ, наиболее благоприятными триместрами является II и III.</p></sec><sec><title>Заключение</title><p>Заключение. Для повышения эффективности прогнозирования развития неблагоприятных событий у пациентов, перенесших ИМ, необходимо учитывать годовые ритмы.</p></sec></abstract><trans-abstract xml:lang="en"><sec><title>Aim</title><p>Aim. To study the 3-year dynamics of the association between cardiovascular events, calendar year seasons and individual annual cycle (IAC) trimesters among patients with myocardial infarction (MI).</p></sec><sec><title>Material and methods</title><p>Material and methods. The study included 324 patients with Day 5-7 Q-MI and left ventricular ejection fraction ≤35 %. During the 3-year follow-up, the following cardiovascular events were registered: death, heart failure progression, repeat MI, unstable angina episodes. Based on individual date of birth, the index number of IAC month when an outcome took place, was identified. Calendar year season was also registered for all cardiovascular events.</p></sec><sec><title>Results</title><p>Results. Winter and summer seasons were associated with the highest risk of cardiovascular events, hospital admissions and deaths; autumn was associated with the minimal risk. The peak of coronary events and deaths was observed in the time window close to the date of birth (IAC trimesters I and IV); the trimesters with the lowest risk were II and III.</p></sec><sec><title>Conclusion</title><p>Conclusion. To increase the effectiveness of predicting cardiovascular events in MI patients, annual cycles should be taken into account.</p></sec></trans-abstract><kwd-group xml:lang="ru"><kwd>инфаркт миокарда</kwd><kwd>прогнозирование</kwd><kwd>годовые ритмы</kwd><kwd>индивидуальный годичный цикл</kwd><kwd>сезоны года</kwd></kwd-group><kwd-group xml:lang="en"><kwd>myocardial infarction</kwd><kwd>prognosis</kwd><kwd>annual rhythms</kwd><kwd>individual annual cycle</kwd><kwd>year seasons</kwd></kwd-group></article-meta></front><back><ref-list><title>References</title><ref id="cit1"><label>1</label><citation-alternatives><mixed-citation xml:lang="ru">Аронов Д.М., Лупанов В.П. Диагностика и лечение ишемической болезни сердца. Качество жизни. Медицина 2003; 2: 16-24.</mixed-citation><mixed-citation xml:lang="en">Аронов Д.М., Лупанов В.П. Диагностика и лечение ишемической болезни сердца. Качество жизни. 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