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<article article-type="research-article" dtd-version="1.3" xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink" xmlns:xsi="http://www.w3.org/2001/XMLSchema-instance" xml:lang="ru"><front><journal-meta><journal-id journal-id-type="publisher-id">cardiovascular</journal-id><journal-title-group><journal-title xml:lang="ru">Кардиоваскулярная терапия и профилактика</journal-title><trans-title-group xml:lang="en"><trans-title>Cardiovascular Therapy and Prevention</trans-title></trans-title-group></journal-title-group><issn pub-type="ppub">1728-8800</issn><issn pub-type="epub">2619-0125</issn><publisher><publisher-name>«SILICEA-POLIGRAF» LLC</publisher-name></publisher></journal-meta><article-meta><article-id pub-id-type="doi">10.15829/1728-8800-2015-5-83-86</article-id><article-id custom-type="elpub" pub-id-type="custom">cardiovascular-171</article-id><article-categories><subj-group subj-group-type="heading"><subject>Research Article</subject></subj-group><subj-group subj-group-type="section-heading" xml:lang="ru"><subject>ОБЗОРЫ</subject></subj-group><subj-group subj-group-type="section-heading" xml:lang="en"><subject>REVIEWS</subject></subj-group></article-categories><title-group><article-title>МИКРОБИОТА КИШЕЧНИКА И ФАКТОРЫ КАРДИОВАСКУЛЯРНОГО РИСКА.  ЧАСТЬ 2. МИКРОБИОТА КИШЕЧНИКА И ОЖИРЕНИЕ</article-title><trans-title-group xml:lang="en"><trans-title>GUT MICROBIOTA AND CARDIOVASCULAR RISK FACTORS. PART 2. GUT MICROBIOTA AND OBESITY</trans-title></trans-title-group></title-group><contrib-group><contrib contrib-type="author" corresp="yes"><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Каштанова</surname><given-names>Д. А.</given-names></name><name name-style="western" xml:lang="en"><surname>Kashtanova</surname><given-names>D. A.</given-names></name></name-alternatives><bio xml:lang="ru"><p>аспирант отдела изучения процессов старения и профилактики возраст-ассоциированных заболеваний</p></bio><email xlink:type="simple">dr.kashtanova@gmail.com</email><xref ref-type="aff" rid="aff-1"/></contrib><contrib contrib-type="author" corresp="yes"><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Ткачева</surname><given-names>О. Н.</given-names></name><name name-style="western" xml:lang="en"><surname>Tkacheva</surname><given-names>O. N.</given-names></name></name-alternatives><bio xml:lang="ru"><p>д. м.н., профессор, руководитель отдела, заместитель директора по научной и лечебной работе</p></bio><xref ref-type="aff" rid="aff-1"/></contrib><contrib contrib-type="author" corresp="yes"><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Бойцов</surname><given-names>С. А.</given-names></name><name name-style="western" xml:lang="en"><surname>Boytsov</surname><given-names>S. A.</given-names></name></name-alternatives><bio xml:lang="ru"><p>д. м.н., профессор, директор</p></bio><xref ref-type="aff" rid="aff-1"/></contrib></contrib-group><aff-alternatives id="aff-1"><aff xml:lang="ru"><institution>ФГБУ "Государственный научно-исследовательский центр профилактической медицины" Минздрава России. Москва, Россия</institution></aff><aff xml:lang="en"><institution>FSBI "State Scientific-Prevention Center of the Prevention Medicine" of the Healthcare Ministry. Moscow, Russia</institution></aff></aff-alternatives><pub-date pub-type="collection"><year>2015</year></pub-date><pub-date pub-type="epub"><day>20</day><month>10</month><year>2015</year></pub-date><volume>14</volume><issue>5</issue><fpage>83</fpage><lpage>86</lpage><permissions><copyright-statement>Copyright &amp;#x00A9; Каштанова Д.А., Ткачева О.Н., Бойцов С.А., 2015</copyright-statement><copyright-year>2015</copyright-year><copyright-holder xml:lang="ru">Каштанова Д.А., Ткачева О.Н., Бойцов С.А.</copyright-holder><copyright-holder xml:lang="en">Kashtanova D.A., Tkacheva O.N., Boytsov S.A.</copyright-holder><license xml:lang="ru" license-type="creative-commons-attribution" xlink:href="https://creativecommons.org/licenses/by/4.0/" xlink:type="simple"><license-p>Данная работа распространяется под лицензией Creative Commons Attribution 4.0.</license-p></license><license xml:lang="en" license-type="creative-commons-attribution" xlink:href="https://creativecommons.org/licenses/by/4.0/" xlink:type="simple"><license-p>This work is licensed under a Creative Commons Attribution 4.0 License.</license-p></license></permissions><self-uri xlink:href="https://cardiovascular.elpub.ru/jour/article/view/171">https://cardiovascular.elpub.ru/jour/article/view/171</self-uri><abstract><p>Значение жировой ткани для организма оказалось намного больше, чем предполагали ранее. Жировая ткань представляет собой обширный эндокринный орган, значение которого трудно переоце­нить, его работа влияет на развитие метаболических нарушений, кардиоваскулярной патологии. В последнее время активно изуча­ется связь ожирения и состава кишечной микробиоты. Состав микробиоты различается в зависимости от характера питания, физической активности, помимо того сама микробиота может вли­ять на усвоение питательных веществ, проницаемость кишечной стенки, на аппетит человека. В представленной статье приведены некоторые механизмы взаимосвязи микробиоты кишечника и ожи­рения, результаты исследований последних лет. </p></abstract><trans-abstract xml:lang="en"><p>The importance of adipose tissue is much greater than it has been expected. Adipose tissue is a large endocrine organ, value of which is difficult to overestimate. Its work influences a lot of metabolic disorders, cardiovascular pathology. Recently, there is active research on the relation of obesity and microbiota contents. It is studied depending on the food type, physical activity, and microbiota itself might influence the absorption of nutrients, permeability of the gut wall, and appetites. The article is focused on several mechanisms of interrelation of gut microbiota and obesity, on the results of last years studies.</p><p> </p></trans-abstract><kwd-group xml:lang="ru"><kwd>микробиота кишечника</kwd><kwd>ожирение</kwd><kwd>короткоцепочечные жирные кислоты</kwd><kwd>адипокины</kwd></kwd-group><kwd-group xml:lang="en"><kwd>gut microbiota</kwd><kwd>obesity</kwd><kwd>short-chain fatty acids</kwd><kwd>adipokines</kwd></kwd-group></article-meta></front><back><ref-list><title>References</title><ref id="cit1"><label>1</label><citation-alternatives><mixed-citation xml:lang="ru">World Health Organization. Global status report on noncommunicable diseases 2014. Geneva: World Health Organization 2014; 280 p.</mixed-citation><mixed-citation xml:lang="en">World Health Organization. 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