cardiovascularКардиоваскулярная терапия и профилактикаCardiovascular Therapy and Prevention1728-88002619-0125«SILICEA-POLIGRAF» LLC10.15829/1728-8800-2011-2-102-109cardiovascular-1760Research ArticleМНЕНИЕ ПО ПРОБЛЕМЕOPINION ON A PROBLEMКомплаентность — определяющий фактор эффективности профилактического применения ацетилсалициловой кислотыCompliance as the major effectiveness determinant in preventive acetylsalicylic acid therapyРафальскийВ. В.RafalskiyV. V.

профессор кафедры управления и экономики фармации

Смоленск, Тел.: (4812) 68 18 11 Факс: (4812) 31 53 10

Smolensk

v.rafalskiy@mail.ruБагликовА. Н.BaglikovA. N.

ординатор кафедры клинической фармакологии

Смоленск

Smolensk

ГОУ ВПО Смоленская государственная медицинская академия Минздравсоцразвития РФSmolensk State Medical Academy201120042011102102109Copyright © Рафальский В.В., Багликов А.Н., 20112011Рафальский В.В., Багликов А.Н.Rafalskiy V.V., Baglikov A.N.Данная работа распространяется под лицензией Creative Commons Attribution 4.0.This work is licensed under a Creative Commons Attribution 4.0 License.https://cardiovascular.elpub.ru/jour/article/view/1760

Применение ацетилсалициловой кислоты (АСК) у пациентов с сердечно-сосудистыми заболеваниями (ССЗ), является одним из самых эффективных подходов в профилактике осложнений ССЗ. У значительной части пациентов, отмечается недостаточно высокая комплаентность длительному профилактическому приему АСК (44-71 %), что сопровождается снижением антитромбоцитарного эффекта препарата и повышением в 2-3 раза риска осложнений, включая инфаркт миокарда (ИМ), ишемический инсульт (ИИ) и др. Улучшить комплаентность пациентов приему АСК возможно за счет улучшения сотрудничества межу врачом и пациентом, информирования и убеждения пациентов в необходимости соблюдения рекомендаций; важное значение имеет назначение кишечнорастворимых форм АСК, улучшающих переносимость препарата. Перспективными являются подходы, основанные на использовании современных упаковок (календарные блистеры) и информационных технологий (телефонные коммуникации, MGMM).

Acetylsalicylic acid (ASA) treatment of patients with cardiovascular disease (CVD) is one of the most effective methods for CVD event prevention. In a substantial proportion of the patients, however, long-term preventive ASA treatment compliance is low (44-71%). Low compliance is associated with reduced antiplatelet effects of ASA and a 2-3-fold increase in the risk of myocardial infarction (MI), ischemic stroke (IS), and other cardiovascular events. ASA therapy compliance could be improved by achieving better collaboration between doctors and patients, while educating patients and explaining the importance of following the doctors’ advice. In addition, enteric-coated ASA forms could play an important role in improving treatment tolerability and, therefore, increasing compliance. Other potentially effective measures include the use of modern packaging (calendar blisters) and information technologies (telephone communication, MGMM).

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The authors declare that there are no conflicts of interest present.