cardiovascularКардиоваскулярная терапия и профилактикаCardiovascular Therapy and Prevention1728-88002619-0125«SILICEA-POLIGRAF» LLC10.15829/1728-8800-2012-3-70-76cardiovascular-1821Research ArticleРАЗНОЕСтрессорные изменения гемодинамики при типе личности Д у здоровых лиц молодого возрастаStress-related hemodynamic response in healthy young individuals with Type D personalityСуминА. Н.SuminA. N.

(контактное лицо) – заведующий лабораторией патологии кровообращения отдела мультифокального атеросклероза

Тел.: (3842) 64-44-61

sumian@cardio.kem.ruСуминаЛ. Ю.SuminaL. Yu.

заведующая оргметодотделом

Тел.: (3842) 64-44-61

sumian@cardio.kem.ruБарбарашН. А.BarbarashN. A.

профессор кафедры нормальной физиологии

Тел.: (3842) 64-44-61

sumian@cardio.kem.ruУРАМН НИИ КПССЗ со РАМНResearch Institute of Complex Cardiovascular Problems, Siberian Branch, Russian Academy of Medical SciencesОбластной клинический госпиталь ветеранов войнRegional Clinical Hospital for War VeteransКемеровская государственная медицинская академия, КемеровоKemerovo State Medical Academy, Kemerovo2012200620121137076Copyright © Сумин А.Н., Сумина Л.Ю., Барбараш Н.А., 20122012Сумин А.Н., Сумина Л.Ю., Барбараш Н.А.Sumin A.N., Sumina L.Y., Barbarash N.A.Данная работа распространяется под лицензией Creative Commons Attribution 4.0.This work is licensed under a Creative Commons Attribution 4.0 License.https://cardiovascular.elpub.ru/jour/article/view/1821

Цель. Изучить стрессорные изменения показателей гемодинамики в ответ на тест с устным счетом (ТУС) у здоровых лиц молодого возраста в зависимости от типа личности Д. Материал и методы: Проведено обследование 80 здоровых (19 юношей и 61 девушка), средний возраст 18,8±0,2 года. Всем обследуемым оценивали психологический статус с помощью опросников DS-14, Шкала депрессии и Спилбергера-Ханина, проводили ТУС с оценкой реакции показателей гемодинамики. Результаты. Тип личности Д (дистрессорный) выявлен среди 32,5% обследованных. Наличие типа Д среди здоровых студентов сочеталось с высоким уровнем личностной и ситуационной тревожности (ЛТр и СТр) и более высокими значениями по шкале депрессии, чем у студентов типа не-Д. У студентов с типом личности Д отмечались большие изменения систолического артериального давления (САД) в ходе ТУС (р=0,05) в отличие от типа не-Д. Выявлена существенная связь между уровнем социального подавления и максимальной частотой сердечных сокращений (ЧСС) в ходе теста ТУС (r=-0,238; p=0,034). У юношей отмечена средней силы корреляционная связь между наличием типа личности Д и изменениями ЧСС (r=-0,508; p=0,026), а также между уровнем негативной возбудимости и динамикой ЧСС в ходе ТУС (r=0,469; p=0,043). Заключение. Дистрессорный тип личности встречается почти у трети обследованных здоровых лиц молодого возраста. Наличие типа Д и выраженность изменений по его подшкалам коррелировали с реакцией гемодинамик при проведении ТУС, при этом отмечены гендерные различия в этих соотношениях. Полученные данные проясняют возможные механизмы влияния типа личности Д на развитие сердечно-сосудистых заболеваний, а также их прогноз.

Aim. To investigate the association between the stress-related hemodynamic response during the mental calculation test (MCT) and the presence of Type D personality in healthy young individuals. Material and methods. The study included 80 healthy individuals (19 men and 61 women; mean age 18,8±0,2 years). Psychological status examination included the DS-14 scale, depression scale, and Spielberger-Khanin scale. MCT was performed with simultaneous assessment of hemodynamic response. Results. Type D personality (distressed type) was observed in 32,5% of the participants. Among young students, Type D personality was associated with higher levels of trait and state anxiety (TA and SA), as well as higher depression scale scores, compared to students without Type D personality. Type D personality was also linked to a more pronounced response of systolic blood pressure (SBP) during MCT (p=0,05). There was a strong correlation between social inhibition levels and maximal heart rate (HR) during MCT (r=-0,238; p=0,034). Young men demonstrated a moderate correlation between Type D personality and HR response (r=-0,508; p=0,026), as well as between negative affectivity levels and HR response during MCT (r=0,469; p=0,043). Conclusion. Distressed personality type was observed in one-third of healthy young participants of the study. Type D personality and its subscales correlated with the hemodynamic response during MCT, with some gender-specific features observed. These findings clarify potential mechanisms of Type D personality effects on the development and prognosis of cardiovascular disease.

тип личности Дстресс-реактивность гемодинамикиtype D personalitystress-related hemodynamic responseReferencesPogosova G.V. Psychological stress and acknowledgement of its value as a first order cardiovascular risk factor. Kardiologiia 2007; 47(2): 65-72. Russian (Погосова Г.В. Признание значимости психоэмоционального стресса в качестве сердечно-сосудистого фактора риска первого порядка. Кардиология 2007; 47(2): 65-72).Pogosova G.V. Psychological stress and acknowledgement of its value as a first order cardiovascular risk factor. Kardiologiia 2007; 47(2): 65-72. Russian (Погосова Г.В. Признание значимости психоэмоционального стресса в качестве сердечно-сосудистого фактора риска первого порядка. Кардиология 2007; 47(2): 65-72).Frasure-Smith N, Lespórance F. Depression and anxiety as predictors of 2-year cardiac events in patients with stable coronary artery disease. Arch Gen Psychiatry 2008; 65(1): 62-71.Frasure-Smith N, Lespórance F. Depression and anxiety as predictors of 2-year cardiac events in patients with stable coronary artery disease. Arch Gen Psychiatry 2008; 65(1): 62-71.Lett HS, Blumenthal JA, Babyak MA, et al. Social support and coronary heart disease: Epidemiologic evidence and implications for treatment. Psychosom Med 2005; 67: 869-78.Lett HS, Blumenthal JA, Babyak MA, et al. Social support and coronary heart disease: Epidemiologic evidence and implications for treatment. Psychosom Med 2005; 67: 869-78.Lavie CJ, Milani RV. Prevalence of hostility in young coronary artery disease patients and effects of cardiac rehabilitation and exercise training. Mayo Clin Proc 2005; 80(3): 335-42.Lavie CJ, Milani RV. Prevalence of hostility in young coronary artery disease patients and effects of cardiac rehabilitation and exercise training. Mayo Clin Proc 2005; 80(3): 335-42.Olson MB, Krantz DS, Kelsey SF, et al.; WISE Study Group. Hostility scores are associated with increased risk of cardiovascular events in women undergoing coronary angiography: a report from the NHLBI-Sponsored WISE Study. Psychosom Med 2005; 67(4): 546-52.Olson MB, Krantz DS, Kelsey SF, et al.; WISE Study Group. Hostility scores are associated with increased risk of cardiovascular events in women undergoing coronary angiography: a report from the NHLBI-Sponsored WISE Study. Psychosom Med 2005; 67(4): 546-52.Chida Y, Steptoe A. The association of anger and hostility with future coronary heart disease: a meta-analytic review of prospective evidence. JACC 2009; 53(11): 936-46.Chida Y, Steptoe A. The association of anger and hostility with future coronary heart disease: a meta-analytic review of prospective evidence. JACC 2009; 53(11): 936-46.Denollet J, Sys SU, Brutsaert DL. Personality and mortality after myocardial infarction. Psychosom Med 1995; 57: 582-91.Denollet J, Sys SU, Brutsaert DL. Personality and mortality after myocardial infarction. Psychosom Med 1995; 57: 582-91.Denollet J. DS14: standard assessment of negative affectivity, social inhibition, and Type D personality. Psychosom Med 2005; 67(1): 89-97.Denollet J. DS14: standard assessment of negative affectivity, social inhibition, and Type D personality. Psychosom Med 2005; 67(1): 89-97.Denollet J, Schiffer AA, Spek V. A general propensity to psychological distress affects cardiovascular outcomes: evidence from research on the type D (distressed) personality profile. Circ Cardiovasc Qual Outcomes 2010; 3(5): 546-57.Denollet J, Schiffer AA, Spek V. A general propensity to psychological distress affects cardiovascular outcomes: evidence from research on the type D (distressed) personality profile. Circ Cardiovasc Qual Outcomes 2010; 3(5): 546-57.Williams L, O’Connor RC, Howard S, et al. Type-D personality mechanisms of effect: the role of health-related behavior and social support. J Psychosom Res 2008; 64(1): 63-9.Williams L, O’Connor RC, Howard S, et al. Type-D personality mechanisms of effect: the role of health-related behavior and social support. J Psychosom Res 2008; 64(1): 63-9.Hausteiner C, Klupsch D, Emeny R, et al.; KORA Investigators. Clustering of negative affectivity and social inhibition in the community: prevalence of type D personality as a cardiovascular risk marker. Psychosom Med 2010; 72(2): 163-71.Hausteiner C, Klupsch D, Emeny R, et al.; KORA Investigators. Clustering of negative affectivity and social inhibition in the community: prevalence of type D personality as a cardiovascular risk marker. Psychosom Med 2010; 72(2): 163-71.Mols F, Denollet J. Type D personality in the general population: a systematic review of health status, mechanisms of disease, and workrelated problems. Health Qual Life Outcomes 2010; 8(1): 9.Mols F, Denollet J. Type D personality in the general population: a systematic review of health status, mechanisms of disease, and workrelated problems. Health Qual Life Outcomes 2010; 8(1): 9.Pelle AJ, Schiffer AA, Smith OR, et al. Inadequate consultation behavior modulates the relationship between Type D personality and impaired health status in chronic heart failure. Int J Cardiol 2010; 142(1): 65-71.Pelle AJ, Schiffer AA, Smith OR, et al. Inadequate consultation behavior modulates the relationship between Type D personality and impaired health status in chronic heart failure. Int J Cardiol 2010; 142(1): 65-71.Hanebuth D, Meinel M, Fischer JE. Health-related quality of life, psychosocial work conditions, and absenteeism in an industrial sample of blue- and white-collar employees: a comparison of potential predictors. J Occup Environ Med 2006; 48(1): 28-37.Hanebuth D, Meinel M, Fischer JE. Health-related quality of life, psychosocial work conditions, and absenteeism in an industrial sample of blue- and white-collar employees: a comparison of potential predictors. J Occup Environ Med 2006; 48(1): 28-37.Denollet J, Conraads VM, Brutsaert DL, et al. Cytokines and immune activation in systolic heart failure: The role of Type D personality. Brain, Behavior and Immunity 2003; 17: 304-9.Denollet J, Conraads VM, Brutsaert DL, et al. Cytokines and immune activation in systolic heart failure: The role of Type D personality. Brain, Behavior and Immunity 2003; 17: 304-9.Conraads VM, Denollet J, De Clerck LS, et al. Type D personality is associated with increased levels of tumour necrosis factor (TNF)-alpha and TNF-alpha receptors in chronic heart failure. Int J Cardiol 2006; 113(1): 34-8.Conraads VM, Denollet J, De Clerck LS, et al. Type D personality is associated with increased levels of tumour necrosis factor (TNF)-alpha and TNF-alpha receptors in chronic heart failure. Int J Cardiol 2006; 113(1): 34-8.Habra ME, Linden W, Anderson JC, Weinberg J. Type D personality is related to cardiovascular and neuroendocrine reactivity to acute stress. J Psychosom Res 2003; 55: 235-45.Habra ME, Linden W, Anderson JC, Weinberg J. Type D personality is related to cardiovascular and neuroendocrine reactivity to acute stress. J Psychosom Res 2003; 55: 235-45.Whitehead DL, Perkins-Porras L, Strike PC, et al. Cortisol awakening response is elevated in acute coronary syndrome patients with Type-D personality. J Psychosom Res 2007; 62: 419-25.Whitehead DL, Perkins-Porras L, Strike PC, et al. Cortisol awakening response is elevated in acute coronary syndrome patients with Type-D personality. J Psychosom Res 2007; 62: 419-25.Molloy GJ, Perkins-Porras L, Strike PC, Steptoe A. Type-D personality and cortisol in survivors of acute coronary syndrome. Psychosom Med 2008; 70(8): 863-8.Molloy GJ, Perkins-Porras L, Strike PC, Steptoe A. Type-D personality and cortisol in survivors of acute coronary syndrome. Psychosom Med 2008; 70(8): 863-8.Williams L, O’Carroll RE, O’Connor RC. Type D personality and cardiac output in response to stress. Psychol Health 2009; 24: 489-500.Williams L, O’Carroll RE, O’Connor RC. Type D personality and cardiac output in response to stress. Psychol Health 2009; 24: 489-500.Barbarash N.A., Tarasenko N.P., Kuvshinov D.Ju. et al. Assess your health for yourself. Tests for self-control. Tomsk: Charodej 2001; 183 p. Russian (Барбараш Н.А., Тарасенко Н.П., Кувшинов Д.Ю. и др. Оцените свое здоровье сами. Тесты для самоконтроля. Томск: Чародей 2001; 183 с).Barbarash N.A., Tarasenko N.P., Kuvshinov D.Ju. et al. Assess your health for yourself. Tests for self-control. Tomsk: Charodej 2001; 183 p. Russian (Барбараш Н.А., Тарасенко Н.П., Кувшинов Д.Ю. и др. Оцените свое здоровье сами. Тесты для самоконтроля. Томск: Чародей 2001; 183 с).Denollet J, de Jonge P, Kuyper A, et al. Depression and Type D personality represent different forms of distress in the Myocardial INfarction and Depression - Intervention Trial (MIND-IT). Psychol Med 2009; 39(5): 749-56.Denollet J, de Jonge P, Kuyper A, et al. Depression and Type D personality represent different forms of distress in the Myocardial INfarction and Depression - Intervention Trial (MIND-IT). Psychol Med 2009; 39(5): 749-56.Pedersen SS, Denollet J, van Gestel YR, et al. Clustering of psychosocial risk factors enhances the risk of depressive symptoms 12-months post percutaneous coronary intervention. Eur J Cardiovasc Prev Rehabil 2008; 15(2): 203-9.Pedersen SS, Denollet J, van Gestel YR, et al. Clustering of psychosocial risk factors enhances the risk of depressive symptoms 12-months post percutaneous coronary intervention. Eur J Cardiovasc Prev Rehabil 2008; 15(2): 203-9.Back SE, Waldrop AE, Saladin ME, et al. Effects of gender and cigarette smoking on reactivity to psychological and pharmacological stress provocation. Psychoneuroendocrinology 2008; 33(5): 560-8.Back SE, Waldrop AE, Saladin ME, et al. Effects of gender and cigarette smoking on reactivity to psychological and pharmacological stress provocation. Psychoneuroendocrinology 2008; 33(5): 560-8.Sato N, Miyake S. Cardiovascular reactivity to mental stress: relationship with menstrual cycle and gender. J Physiol Anthropol Appl Human Sci 2004; 23(6): 215-23.Sato N, Miyake S. Cardiovascular reactivity to mental stress: relationship with menstrual cycle and gender. J Physiol Anthropol Appl Human Sci 2004; 23(6): 215-23.Chida Y, Steptoe A. Greater cardiovascular responses to laboratory mental stress are associated with poor subsequent cardiovascular risk status: a meta-analysis of prospective evidence. Hypertension 2010; 55(4): 1026- 32.Chida Y, Steptoe A. Greater cardiovascular responses to laboratory mental stress are associated with poor subsequent cardiovascular risk status: a meta-analysis of prospective evidence. Hypertension 2010; 55(4): 1026- 32.Hassellund SS, Flaa A, Sandvik L, et al. Long-term stability of cardiovascular and catecholamine responses to stress tests: an 18-year follow-up study. Hypertension 2010; 55(1): 131-6.Hassellund SS, Flaa A, Sandvik L, et al. Long-term stability of cardiovascular and catecholamine responses to stress tests: an 18-year follow-up study. Hypertension 2010; 55(1): 131-6.Sher L. Type D personality: the heart, stress, and cortisol. QJM 2005; 98(5): 323-9.Sher L. Type D personality: the heart, stress, and cortisol. QJM 2005; 98(5): 323-9.

The authors declare that there are no conflicts of interest present.