cardiovascularКардиоваскулярная терапия и профилактикаCardiovascular Therapy and Prevention1728-88002619-0125«SILICEA-POLIGRAF» LLC10.15829/1728-8800-2011-3-113-122cardiovascular-1843Research ArticleОБЗОРЫREVIEWSСовременные возможности ультразвуковых методов оценки атеросклеротического процесса у больных семейной гиперхолестеринемиейModern ultrasound methods and atherosclerosis assessment in patients with familial hypercholesterolemiaЕршоваА. И.ErshovaA. I.

аспирант, лаборант-исследователь лаборатории ультразвуковых методов исследования сосудов

Москва, Тел.: 8(495) 414-65-96, 8 (916) 559-85-36

alersh@mail.ruМешковА. Н.MeshkovA. N.

научный сотрудник отдела возрастных проблем сердечно-сосудистых заболеваний

Москва

БойцовС. А.BoytsovS. A.

руководитель отдела возрастных проблем сердечно-сосудистых заболеваний

Москва

БалахоноваТ. В.BalakhonovaT. V.

ведущий научный сотрудник отдела новых методов диагностики, руководитель лаборатории ультразвуковых методов исследования сосудов

Москва

ФГУ “Российский кардиологический научно-производственный комплекс” Министерства здравоохранения и социального развития Российской ФедерацииRussian Cardiology Scientific and Clinical Complex201120062011103113122Copyright © Ершова А.И., Мешков А.Н., Бойцов С.А., Балахонова Т.В., 20112011Ершова А.И., Мешков А.Н., Бойцов С.А., Балахонова Т.В.Ershova A.I., Meshkov A.N., Boytsov S.A., Balakhonova T.V.Данная работа распространяется под лицензией Creative Commons Attribution 4.0.This work is licensed under a Creative Commons Attribution 4.0 License.https://cardiovascular.elpub.ru/jour/article/view/1843

Семейная гиперхолестеринемия (СГХС) — заболевание, сопровождающееся ранним развитием и быстрым прогрессированием атеросклероза. Учитывая, что распространенность СГХС в России растет, изучение методов диагностики атеросклероза у больных СГХС особенно актуально. Ультразвуковой метод исследования артерий — информативный, доступный, безопасный для оценки атеросклеротических изменений. В настоящее время имеющиеся методы ультразвукового исследования сосудов позволяют всесторонне описать стенку сосуда: дать структурную (качественную и количественную) и функциональную характеристики. Большая часть ультразвуковых параметров состояния артериальной стенки еще не нашла широкого применения в клинической практике, либо используется преимущественно в научных целях, либо находится на стадии разработки. Наиболее перспективными для применения в клинической практике у больных СГХС представляются маркеры, характеризующие одновременно степень выраженности и распространенности атеросклеротического процесса, такие как суммарная высота бляшек, лодыжечно-плечевой индекс, количество бляшек.

Familial hypercholesterolemia (FHCH) is characterised by early atherosclerosis development and its fast progression. The prevalence of FHCH inRussiahas been increasing, therefore, it is important to evaluate the potential of various methods for atherosclerosis diagnostics. Arterial ultrasound is an informative, accessible, and safe method for evaluating atherosclerotic vascular changes. The modern ultrasound methods allow describing vascular wall status in detail, including qualitative and quantitative characteristics of its structure and function. At the same time, most ultrasound characteristics of arterial wall are used in research settings or are under development, and not implemented into clinical practice. The most promising parameters, applicable for clinical use in FHCH patients, simultaneously describe atherosclerosis severity and its localization, such as total plaque height, ankle-brachial index, and plaque number.

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The authors declare that there are no conflicts of interest present.