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<article article-type="research-article" dtd-version="1.3" xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink" xmlns:xsi="http://www.w3.org/2001/XMLSchema-instance" xml:lang="ru"><front><journal-meta><journal-id journal-id-type="publisher-id">cardiovascular</journal-id><journal-title-group><journal-title xml:lang="ru">Кардиоваскулярная терапия и профилактика</journal-title><trans-title-group xml:lang="en"><trans-title>Cardiovascular Therapy and Prevention</trans-title></trans-title-group></journal-title-group><issn pub-type="ppub">1728-8800</issn><issn pub-type="epub">2619-0125</issn><publisher><publisher-name>«SILICEA-POLIGRAF» LLC</publisher-name></publisher></journal-meta><article-meta><article-id pub-id-type="doi">10.15829/1728-8800-2012-4-93-100</article-id><article-id custom-type="elpub" pub-id-type="custom">cardiovascular-1881</article-id><article-categories><subj-group subj-group-type="heading"><subject>Research Article</subject></subj-group><subj-group subj-group-type="section-heading" xml:lang="ru"><subject>ОБЗОРЫ</subject></subj-group><subj-group subj-group-type="section-heading" xml:lang="en"><subject>REVIEWS</subject></subj-group></article-categories><title-group><article-title>Старение сосудов: основные признаки и механизмы</article-title><trans-title-group xml:lang="en"><trans-title>Vascular ageing: main symptoms and mechanisms</trans-title></trans-title-group></title-group><contrib-group><contrib contrib-type="author" corresp="yes"><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Стражеско</surname><given-names>И. Д.</given-names></name><name name-style="western" xml:lang="en"><surname>Strazhesko</surname><given-names>I. D.</given-names></name></name-alternatives><bio xml:lang="ru"><p>(контактное лицо) – в.н.с. отдела комплексного снижения риска неинфекционных заболеваний</p><p>Тел.: (985) 210-73-27</p></bio><email xlink:type="simple">istrazhesko@gmail.com</email><xref ref-type="aff" rid="aff-1"/></contrib><contrib contrib-type="author" corresp="yes"><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Акашева</surname><given-names>Д. У.</given-names></name><name name-style="western" xml:lang="en"><surname>Akasheva</surname><given-names>D. U.</given-names></name></name-alternatives><bio xml:lang="ru"><p>с.н.с. отдела</p><p>Тел.: (985) 210-73-27</p></bio><email xlink:type="simple">istrazhesko@gmail.com</email><xref ref-type="aff" rid="aff-1"/></contrib><contrib contrib-type="author" corresp="yes"><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Дудинская</surname><given-names>Е. Н.</given-names></name><name name-style="western" xml:lang="en"><surname>Dudinskaya</surname><given-names>E. N.</given-names></name></name-alternatives><bio xml:lang="ru"><p>с.н.с. отдела</p><p>Тел.: (985) 210-73-27</p></bio><email xlink:type="simple">istrazhesko@gmail.com</email><xref ref-type="aff" rid="aff-1"/></contrib><contrib contrib-type="author" corresp="yes"><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Ткачева</surname><given-names>О. Н.</given-names></name><name name-style="western" xml:lang="en"><surname>Tkacheva</surname><given-names>O. N.</given-names></name></name-alternatives><bio xml:lang="ru"><p>руководитель отдела</p><p>Тел.: (985) 210-73-27</p></bio><email xlink:type="simple">istrazhesko@gmail.com</email><xref ref-type="aff" rid="aff-1"/></contrib></contrib-group><aff-alternatives id="aff-1"><aff xml:lang="ru"><institution>ФГБУ Государственный научно-исследовательский центр профилактической медицины Минздравсоцразвития России, Москва</institution></aff><aff xml:lang="en"><institution>State Research Centre for Preventive Medicine, Moscow</institution></aff></aff-alternatives><pub-date pub-type="collection"><year>2012</year></pub-date><pub-date pub-type="epub"><day>20</day><month>08</month><year>2012</year></pub-date><volume>11</volume><issue>4</issue><fpage>93</fpage><lpage>100</lpage><permissions><copyright-statement>Copyright &amp;#x00A9; Стражеско И.Д., Акашева Д.У., Дудинская Е.Н., Ткачева О.Н., 2012</copyright-statement><copyright-year>2012</copyright-year><copyright-holder xml:lang="ru">Стражеско И.Д., Акашева Д.У., Дудинская Е.Н., Ткачева О.Н.</copyright-holder><copyright-holder xml:lang="en">Strazhesko I.D., Akasheva D.U., Dudinskaya E.N., Tkacheva O.N.</copyright-holder><license xml:lang="ru" license-type="creative-commons-attribution" xlink:href="https://creativecommons.org/licenses/by/4.0/" xlink:type="simple"><license-p>Данная работа распространяется под лицензией Creative Commons Attribution 4.0.</license-p></license><license xml:lang="en" license-type="creative-commons-attribution" xlink:href="https://creativecommons.org/licenses/by/4.0/" xlink:type="simple"><license-p>This work is licensed under a Creative Commons Attribution 4.0 License.</license-p></license></permissions><self-uri xlink:href="https://cardiovascular.elpub.ru/jour/article/view/1881">https://cardiovascular.elpub.ru/jour/article/view/1881</self-uri><abstract><p>Обсуждаются основные морфологические и функциональные изменения сосудов в процессе старения, механизмы развития, возможности их коррекции.</p></abstract><trans-abstract xml:lang="en"><p>The authors discuss major structural and functional vascular changes accompanying ageing, the mechanisms of their development, and potential methods of their correction.</p></trans-abstract><kwd-group xml:lang="ru"><kwd>сосудистое старение</kwd><kwd>жесткость артерий</kwd><kwd>эндотелиальная дисфункция</kwd></kwd-group><kwd-group xml:lang="en"><kwd>vascular ageing</kwd><kwd>arterial stiffness</kwd><kwd>endothelial dysfunction</kwd></kwd-group></article-meta></front><back><ref-list><title>References</title><ref id="cit1"><label>1</label><citation-alternatives><mixed-citation xml:lang="ru">Lim MA, Townsend RR. 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