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<article article-type="research-article" dtd-version="1.3" xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink" xmlns:xsi="http://www.w3.org/2001/XMLSchema-instance" xml:lang="ru"><front><journal-meta><journal-id journal-id-type="publisher-id">cardiovascular</journal-id><journal-title-group><journal-title xml:lang="ru">Кардиоваскулярная терапия и профилактика</journal-title><trans-title-group xml:lang="en"><trans-title>Cardiovascular Therapy and Prevention</trans-title></trans-title-group></journal-title-group><issn pub-type="ppub">1728-8800</issn><issn pub-type="epub">2619-0125</issn><publisher><publisher-name>«SILICEA-POLIGRAF» LLC</publisher-name></publisher></journal-meta><article-meta><article-id pub-id-type="doi">10.15829/1728-8800-2011-4-110-116</article-id><article-id custom-type="elpub" pub-id-type="custom">cardiovascular-1906</article-id><article-categories><subj-group subj-group-type="heading"><subject>Research Article</subject></subj-group><subj-group subj-group-type="section-heading" xml:lang="ru"><subject>МНЕНИЕ ПО ПРОБЛЕМЕ</subject></subj-group><subj-group subj-group-type="section-heading" xml:lang="en"><subject>OPINION ON A PROBLEM</subject></subj-group></article-categories><title-group><article-title>Тактика лечения при неэффективности монотерапии статинами</article-title><trans-title-group xml:lang="en"><trans-title>Ineffective statin monotherapy: alternative therapeutic strategy</trans-title></trans-title-group></title-group><contrib-group><contrib contrib-type="author" corresp="yes"><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Сергиенко</surname><given-names>И. В.</given-names></name><name name-style="western" xml:lang="en"><surname>Sergienko</surname><given-names>I. V.</given-names></name></name-alternatives><bio xml:lang="ru"><p>с.н.с. отдела проблем атеросклероза</p><p>Москва, Тел.: 495)414-72-86, 8-903-149-22-53 </p></bio><bio xml:lang="en"><p>Moscow</p></bio><email xlink:type="simple">igorcardio@mail.ru</email><xref ref-type="aff" rid="aff-1"/></contrib></contrib-group><aff-alternatives id="aff-1"><aff xml:lang="ru"><institution>ФГУ Российский кардиологический научно-производственный комплекс</institution></aff><aff xml:lang="en"><institution>Russian Cardiology Scientific and Clinical Complex</institution></aff></aff-alternatives><pub-date pub-type="collection"><year>2011</year></pub-date><pub-date pub-type="epub"><day>20</day><month>08</month><year>2011</year></pub-date><volume>10</volume><issue>4</issue><fpage>110</fpage><lpage>116</lpage><permissions><copyright-statement>Copyright &amp;#x00A9; Сергиенко И.В., 2011</copyright-statement><copyright-year>2011</copyright-year><copyright-holder xml:lang="ru">Сергиенко И.В.</copyright-holder><copyright-holder xml:lang="en">Sergienko I.V.</copyright-holder><license xml:lang="ru" license-type="creative-commons-attribution" xlink:href="https://creativecommons.org/licenses/by/4.0/" xlink:type="simple"><license-p>Данная работа распространяется под лицензией Creative Commons Attribution 4.0.</license-p></license><license xml:lang="en" license-type="creative-commons-attribution" xlink:href="https://creativecommons.org/licenses/by/4.0/" xlink:type="simple"><license-p>This work is licensed under a Creative Commons Attribution 4.0 License.</license-p></license></permissions><self-uri xlink:href="https://cardiovascular.elpub.ru/jour/article/view/1906">https://cardiovascular.elpub.ru/jour/article/view/1906</self-uri><abstract/><trans-abstract xml:lang="en"/><kwd-group xml:lang="ru"><kwd>эзетимиб</kwd><kwd>всасывание холестерина</kwd><kwd>белок</kwd><kwd>переносящий эфиры холестерина</kwd><kwd>холестерол эстераза</kwd><kwd>ацил коэнзим А холестерол ацилтрансфераза</kwd><kwd>белок Неймана-Пика</kwd><kwd>тип l1</kwd></kwd-group><kwd-group xml:lang="en"><kwd>Ezetimibe</kwd><kwd>cholesterol absorption</kwd><kwd>cholesteryl ester transfer protein</kwd><kwd>cholesterol esterase</kwd><kwd>acyl-CoA: cholesterol acyltransferase</kwd><kwd>Niemann-Pick C1-like 1 protein</kwd></kwd-group></article-meta></front><back><ref-list><title>References</title><ref id="cit1"><label>1</label><citation-alternatives><mixed-citation xml:lang="ru">Howles PN. 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