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<article article-type="research-article" dtd-version="1.3" xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink" xmlns:xsi="http://www.w3.org/2001/XMLSchema-instance" xml:lang="ru"><front><journal-meta><journal-id journal-id-type="publisher-id">cardiovascular</journal-id><journal-title-group><journal-title xml:lang="ru">Кардиоваскулярная терапия и профилактика</journal-title><trans-title-group xml:lang="en"><trans-title>Cardiovascular Therapy and Prevention</trans-title></trans-title-group></journal-title-group><issn pub-type="ppub">1728-8800</issn><issn pub-type="epub">2619-0125</issn><publisher><publisher-name>«SILICEA-POLIGRAF» LLC</publisher-name></publisher></journal-meta><article-meta><article-id pub-id-type="doi">10.15829/1728-8800-2011-6-64-69</article-id><article-id custom-type="elpub" pub-id-type="custom">cardiovascular-1972</article-id><article-categories><subj-group subj-group-type="heading"><subject>Research Article</subject></subj-group><subj-group subj-group-type="section-heading" xml:lang="ru"><subject>ЭПИДЕМИОЛОГИЯ И ПРОФИЛАКТИКА</subject></subj-group><subj-group subj-group-type="section-heading" xml:lang="en"><subject>EPIDEMIOLOGY AND PREVENTION</subject></subj-group></article-categories><title-group><article-title>Ассоциации между С-реактивным белком и социальнодемографическими показателями у москвичей 55 лет и старше</article-title><trans-title-group xml:lang="en"><trans-title>C-reactive protein and sociodemographic parameters in Moscow residents aged 55 years and older</trans-title></trans-title-group></title-group><contrib-group><contrib contrib-type="author" corresp="yes"><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Шальнова</surname><given-names>С. А.</given-names></name><name name-style="western" xml:lang="en"><surname>Shalnova</surname><given-names>S. A.</given-names></name></name-alternatives><bio xml:lang="ru"><p>руководитель отдела планирования и координации научных исследований;</p><p>в.н.с.</p><p>Москва</p></bio><bio xml:lang="en"/><email xlink:type="simple">sshalnova@gnicpm.ru</email><xref ref-type="aff" rid="aff-1"/></contrib><contrib contrib-type="author" corresp="yes"><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Жукова</surname><given-names>В. А.</given-names></name><name name-style="western" xml:lang="en"><surname>Zhukova</surname><given-names>V. A.</given-names></name></name-alternatives><bio xml:lang="ru"><p>аспирант</p><p>Москва</p></bio><bio xml:lang="en"/><xref ref-type="aff" rid="aff-2"/></contrib><contrib contrib-type="author" corresp="yes"><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Метельская</surname><given-names>В. А.</given-names></name><name name-style="western" xml:lang="en"><surname>Metelskaya</surname><given-names>V. A.</given-names></name></name-alternatives><bio xml:lang="ru"><p>руководитель отдела, Ученый секретарь</p><p>Москва</p></bio><bio xml:lang="en"/><xref ref-type="aff" rid="aff-2"/></contrib><contrib contrib-type="author" corresp="yes"><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Деев</surname><given-names>А. Д.</given-names></name><name name-style="western" xml:lang="en"><surname>Deev</surname><given-names>A. D.</given-names></name></name-alternatives><bio xml:lang="ru"><p>руководитель лаборатории биостатистики</p><p>Москва</p></bio><bio xml:lang="en"/><xref ref-type="aff" rid="aff-2"/></contrib><contrib contrib-type="author" corresp="yes"><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Худяков</surname><given-names>М. Б.</given-names></name><name name-style="western" xml:lang="en"><surname>Khudyakov</surname><given-names>M. B.</given-names></name></name-alternatives><bio xml:lang="ru"><p>ведущий инженер</p><p>Москва</p></bio><bio xml:lang="en"/><xref ref-type="aff" rid="aff-2"/></contrib><contrib contrib-type="author" corresp="yes"><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Александри</surname><given-names>А. Л.</given-names></name><name name-style="western" xml:lang="en"><surname>Aleksandri</surname><given-names>A. L.</given-names></name></name-alternatives><bio xml:lang="ru"><p>с.н.с.</p><p>Москва</p></bio><bio xml:lang="en"/><xref ref-type="aff" rid="aff-2"/></contrib><contrib contrib-type="author" corresp="yes"><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Баланова</surname><given-names>Ю. А.</given-names></name><name name-style="western" xml:lang="en"><surname>Balanova</surname><given-names>Yu. A.</given-names></name></name-alternatives><bio xml:lang="ru"><p>с.н.с.</p><p>Москва</p></bio><bio xml:lang="en"/><xref ref-type="aff" rid="aff-2"/></contrib><contrib contrib-type="author" corresp="yes"><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Капустина</surname><given-names>А. В.</given-names></name><name name-style="western" xml:lang="en"><surname>Kapustina</surname><given-names>A. V.</given-names></name></name-alternatives><bio xml:lang="ru"><p>с.н.с.</p><p>Москва</p></bio><bio xml:lang="en"/><xref ref-type="aff" rid="aff-2"/></contrib><contrib contrib-type="author" corresp="yes"><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Константинов</surname><given-names>В. В.</given-names></name><name name-style="western" xml:lang="en"><surname>Konstantinov</surname><given-names>V. V.</given-names></name></name-alternatives><bio xml:lang="ru"><p>в.н.с.</p><p>Москва</p></bio><bio xml:lang="en"/><xref ref-type="aff" rid="aff-2"/></contrib><contrib contrib-type="author" corresp="yes"><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Кукушкин</surname><given-names>С. К.</given-names></name><name name-style="western" xml:lang="en"><surname>Kukushkin</surname><given-names>S. K.</given-names></name></name-alternatives><bio xml:lang="ru"><p>в.н.с.</p><p>Москва</p></bio><bio xml:lang="en"/><xref ref-type="aff" rid="aff-2"/></contrib><contrib contrib-type="author" corresp="yes"><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Лельчук</surname><given-names>И. Н.</given-names></name><name name-style="western" xml:lang="en"><surname>Lel’chuk</surname><given-names>I. N.</given-names></name></name-alternatives><bio xml:lang="ru"><p>н.с.</p><p>Москва</p></bio><bio xml:lang="en"/><xref ref-type="aff" rid="aff-2"/></contrib><contrib contrib-type="author" corresp="yes"><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Платонова</surname><given-names>Е. В.</given-names></name><name name-style="western" xml:lang="en"><surname>Platonova</surname><given-names>E. V.</given-names></name></name-alternatives><bio xml:lang="ru"><p>н.с.</p><p>Москва</p></bio><bio xml:lang="en"/><xref ref-type="aff" rid="aff-2"/></contrib><contrib contrib-type="author" corresp="yes"><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Школьникова</surname><given-names>М. А.</given-names></name><name name-style="western" xml:lang="en"><surname>Shkolnikova</surname><given-names>M. A.</given-names></name></name-alternatives><bio xml:lang="ru"><p>руководитель Детского научно-практического центра нарушений сердечного ритма</p><p>Москва</p></bio><bio xml:lang="en"/><xref ref-type="aff" rid="aff-3"/></contrib></contrib-group><aff-alternatives id="aff-1"><aff xml:lang="ru">ФГУ Российский кардиологический научно-производственный комплекс Минздравсоцразвития России;&#13;
ФГУ Государственный научно-исследовательский центр профилактической медицины Минздравсоцразвития России<country>Россия</country></aff><aff xml:lang="en">Russian Cardiology Scientific and Clinical Complex;&#13;
State Research Centre for Preventive Medicine<country>Russian Federation</country></aff></aff-alternatives><aff-alternatives id="aff-2"><aff xml:lang="ru">ФГУ Государственный научно-исследовательский центр профилактической медицины Минздравсоцразвития России<country>Россия</country></aff><aff xml:lang="en">State Research Centre for Preventive Medicine<country>Russian Federation</country></aff></aff-alternatives><aff-alternatives id="aff-3"><aff xml:lang="ru">ФГУ Научно-исследовательский институт педиатрии и детской хирургии&#13;
Минздравсоцразвития России<country>Россия</country></aff><aff xml:lang="en">Research Institute of Pediatrics and Pediatric Surgery<country>Russian Federation</country></aff></aff-alternatives><pub-date pub-type="collection"><year>2011</year></pub-date><pub-date pub-type="epub"><day>20</day><month>12</month><year>2011</year></pub-date><volume>10</volume><issue>6</issue><fpage>64</fpage><lpage>69</lpage><permissions><copyright-statement>Copyright &amp;#x00A9; Шальнова С.А., Жукова В.А., Метельская В.А., Деев А.Д., Худяков М.Б., Александри А.Л., Баланова Ю.А., Капустина А.В., Константинов В.В., Кукушкин С.К., Лельчук И.Н., Платонова Е.В., Школьникова М.А., 2011</copyright-statement><copyright-year>2011</copyright-year><copyright-holder xml:lang="ru">Шальнова С.А., Жукова В.А., Метельская В.А., Деев А.Д., Худяков М.Б., Александри А.Л., Баланова Ю.А., Капустина А.В., Константинов В.В., Кукушкин С.К., Лельчук И.Н., Платонова Е.В., Школьникова М.А.</copyright-holder><copyright-holder xml:lang="en">Shalnova S.A., Zhukova V.A., Metelskaya V.A., Deev A.D., Khudyakov M.B., Aleksandri A.L., Balanova Y.A., Kapustina A.V., Konstantinov V.V., Kukushkin S.K., Lel’chuk I.N., Platonova E.V., Shkolnikova M.A.</copyright-holder><license license-type="creative-commons-attribution" xlink:href="https://creativecommons.org/licenses/by/4.0/" xlink:type="simple"><license-p>This work is licensed under a Creative Commons Attribution 4.0 License.</license-p></license></permissions><self-uri xlink:href="https://cardiovascular.elpub.ru/jour/article/view/1972">https://cardiovascular.elpub.ru/jour/article/view/1972</self-uri><abstract><p>Цель. Высокочувствительный C-реактивный белок (вчСРБ) рассматривается в настоящее время как значимый маркер риска сердечно-сосудистых заболеваний (ССЗ). Впервые оценить популяционные характеристики вчСРБ в выборке москвичей возрастной категории ≥ 55 лет. Материал и методы. В анализ включены 1851 человек, с откликом 65 %, которые были обследованы в рамках проекта “Стресс, Старение и Здоровье в России”. Результаты. Распределение СРБ в популяции мужчин и женщин практически одинаково и смещено в сторону высоких значений. Размах значений СРБ от минимального до максимального составляет у мужчин: 0,5-69,5 мг/дл, для женщин: 0,5-75 мг/л, медиана равна 1,5 мг/л. Средние уровни СРБ у мужчин несколько выше, чем у женщин, и составляют 3,4±0,19 и 3,1±0,15 соответственно (р=0,36). В целом в выборке не отмечено возрастной динамики средних уровней СРБ у мужчин и женщин. Распространенность высокого СРБ (&gt;3 мг/л) с возрастом увеличивается от 31,2 % в наиболее молодой возрастной группе до 36,2 % у тех, кому уже ≥ 75 лет, не достигая статистической значимости. Острое воспаление (СРБ &gt;10 мг/л) наблюдались у 85 человек (4,5 %), т. е. у 42 мужчин и 43 женщин. Отмечаются достоверные обратные ассоциации между статусом образования и СРБ. После стандартизации на пол и возраст низкий уровень образования остается значимым индикатором повышенного СРБ. Заключение. В исследовании не получены ассоциации между СРБ полом и возрастом, однако лица с высоким и средним образовательным цензом имеют достоверно более низкий уровень этого показателя по сравнению с теми, у кого образовательный статус ниже среднего.</p></abstract><trans-abstract xml:lang="en"><p>Aim. High-sensitive C-reactive protein (hsCRP) is currently regarded as an important marker of cardiovascular disease (CVD). The aim of the study was to assess the population characteristics of hsCRP in the sample of Moscow residents aged 55 years and older. Material and methods. The analysis included 1851 people (response rate 65 %), who participated in the SAHR (Stress, Aging, and Health in Russia) study. Results. The hsCRP levels were similar in men and women, with the right-skewed distribution. The hsCRP values ranged from 0,5 to 69,5 mg/dl in men (median 1,5 mg/l), and from 0,5 to 75 mg/l in women (median 1,5 mg/l). The mean hsCRP levels were slightly higher in men than in women (3,4±0,19 vs. 3,1±0,15, respectively; р=0,36). Overall, there was no marked age-related dynamics of hsCRP levels in men or women. The prevalence of high hsCRP levels (&gt;3 mg/l) non-significantly increased from 31,2 % in the youngest age group to 36,2 % in those aged 75 years and older. Acute inflammation (hsCRP levels &gt;10 mg/l) was registered in 85 participants (4,5 %), including 42 men and 43 women. After adjustment for age and gender, the lower education level remained a significant predictor of hsCRP elevation. Conclusion. No clear associations between hsCRP and age or gender were observed. However, participants with university and secondary education had significantly lower hsCRP concentrations, compared to their peers with education level lower than secondary.</p></trans-abstract><kwd-group xml:lang="ru"><kwd>С-реактивный белок</kwd><kwd>распределение</kwd><kwd>пожилые</kwd><kwd>пол</kwd><kwd>возраст</kwd><kwd>образование</kwd></kwd-group><kwd-group xml:lang="en"><kwd>C-reactive protein</kwd><kwd>distribution</kwd><kwd>elderly people</kwd><kwd>gender</kwd><kwd>age</kwd><kwd>education</kwd></kwd-group></article-meta></front><back><ref-list><title>References</title><ref id="cit1"><label>1</label><citation-alternatives><mixed-citation xml:lang="ru">The World Health Report 2002: Reducing risks Promoting healthy life. 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