cardiovascularКардиоваскулярная терапия и профилактикаCardiovascular Therapy and Prevention1728-88002619-0125«SILICEA-POLIGRAF» LLC10.15829/1728-8800-2011-6-105-111cardiovascular-1979Research ArticleОБЗОРЫREVIEWSКлиническое значение аполипопротеинов А и ВClinical role of apolipoproteins A and BЧумаковаГ. А.ChumakovaG. A.

профессор кафедры госпитальной и поликлинической терапии;

в.н.с. отдела мультифокального атеросклероза

Тел.: 8-903-910-80-40

g.a.chumakova@mail.ruГриценкоО. В.GritsenkoO. V.ВеселовскаяН. Г.VeselovskayaN. G.

с.н.с. отдела мультифокального атеросклероза;

врач отделения артериальной гипертонии

ВахромееваЕ. В.VakhromeevaE. V.КозаренкоА. А.KozarenkoA. A.

н.с. отдела мультифокального атеросклероза;

аспирант

Алтайский государственный медицинский университет, Барнаул; Научно-исследовательский институт комплексных проблем сердечно-сосудистых заболеваний Сибирского отделения РАМН, КемеровоAltay State Medical University, Barnaul; Research Institute of Complex Cardiovascular Problems, Siberian Branch, Russian Academy of Medical Sciences, KemerovoАлтайский государственный медицинский университет, БарнаулAltay State Medical University, BarnaulНаучно-исследовательский институт комплексных проблем сердечно-сосудистых заболеваний Сибирского отделения РАМН, Кемерово; Алтайский краевой кардиологический диспансер, БарнаулResearch Institute of Complex Cardiovascular Problems, Siberian Branch, Russian Academy of Medical Sciences, Kemerovo; Altay Region Cardiology Dispanser, BarnaulАлтайский краевой кардиологический диспансер, БарнаулAltay Region Cardiology Dispanser, Barnaul201120122011106105111Copyright © Чумакова Г.А., Гриценко О.В., Веселовская Н.Г., Вахромеева Е.В., Козаренко А.А., 20112011Чумакова Г.А., Гриценко О.В., Веселовская Н.Г., Вахромеева Е.В., Козаренко А.А.Chumakova G.A., Gritsenko O.V., Veselovskaya N.G., Vakhromeeva E.V., Kozarenko A.A.Данная работа распространяется под лицензией Creative Commons Attribution 4.0.This work is licensed under a Creative Commons Attribution 4.0 License.https://cardiovascular.elpub.ru/jour/article/view/1979

Оценка и коррекция традиционных параметров атерогенной дислипидемии являются важными, но не достаточными методами наблюдения за прогрессом атеросклероза, в т.ч. коронарного. Для более точной диагностической и терапевтической оценки необходимо определять уровни АпоАI, АпоВ и их отношение, причем, чем ниже АпоВ/АпоАI, тем ниже сердечно-сосудистый риск.

The assessment and correction of the traditional parameters of atherogenic dyslipidemia are important, but not exclusive methods in the management of atherosclerosis, including coronary artery atherosclerosis. More accurate diagnostic and therapeutic assessment requires the measurement of apolipoprotein (Apo) A, ApoB, and their ratio.Lower ApoB/ApoAI ratio values denote lower levels of cardiovascular risk.

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The authors declare that there are no conflicts of interest present.