cardiovascularКардиоваскулярная терапия и профилактикаCardiovascular Therapy and Prevention1728-88002619-0125«SILICEA-POLIGRAF» LLCcardiovascular-2024Research ArticleОБЗОРЫREVIEWSПрименение антигипертензивного препарата комбинированного действия урапидила в клинической практикеClinical use of a combined-action antihypertensive medication urapidilГапоноваН. И.GaponovaN. I.

доцент кафедры скорой медицинской помощи

nade-gaponova@yandex.ruАбдрахмановВ. Р.AbdrakhmanovV. R.

профессор кафедры скорой медицинской помощи

ПлавуновН. Ф.PlavunovN. F.

главный врач

ФилатовА. В.FilatovA. V.

врач-кардиолог Скорой медицинской помощи г. Раменское

ОрловВ. С.OrlovV. S.

врач-кардиолог

ФилипповД. В.FilippovD. V.

врач-невролог

ТерещенкоС. Н.TereshchenkoS. N.

заведующий кафедрой скорой медицинской помощи ФПДО

ГОУ ВПО Московский государственный медико-стоматологический университет Росздрава. МоскваMoscow State Medico-Stomatological University. MoscowСтанция скорой и неотложной медицинской помощи им. А.С. Пучкова г. МосквыA.S. Puchkov Urgent Medical Care Centre20102002201091107112Copyright © Гапонова Н.И., Абдрахманов В.Р., Плавунов Н.Ф., Филатов А.В., Орлов В.С., Филиппов Д.В., Терещенко С.Н., 20102010Гапонова Н.И., Абдрахманов В.Р., Плавунов Н.Ф., Филатов А.В., Орлов В.С., Филиппов Д.В., Терещенко С.Н.Gaponova N.I., Abdrakhmanov V.R., Plavunov N.F., Filatov A.V., Orlov V.S., Filippov D.V., Tereshchenko S.N.Данная работа распространяется под лицензией Creative Commons Attribution 4.0.This work is licensed under a Creative Commons Attribution 4.0 License.https://cardiovascular.elpub.ru/jour/article/view/2024

В настоящее время комбинированная антигипертензивная терапия рассматривается в качестве основной стратегии лечения больных артериальной гипертензией. К числу эффективных препаратов комбинированного действия относится гибридный препарат урапидил, совмещающий в одной химической структуре центральный антигипертензивный эффект с периферической вазодилатацией. В обзоре обсуждаются результаты клинических и экспериментальных исследований, посвященных анализу антигипертензивного действия урапидила, рекомендованы области применения, а также подчеркнуты хорошая переносимость и безопасность препарата.

Currently, combined antihypertensive therapy is considered as the leading strategy in the management of patients with arterial hypertension. One of the effective combined antihypertensive medications is a hybrid agent urapidil, which chemical structure provides a combination of central antihypertensive action and peripheral vasodilatation. This review discusses the results of the clinical and experimental studies on urapidil antihypertensive effectiveness. The clinical use of the medication, as well as its good tolerability and safety, is also discussed.

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The authors declare that there are no conflicts of interest present.