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<article article-type="research-article" dtd-version="1.3" xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink" xmlns:xsi="http://www.w3.org/2001/XMLSchema-instance" xml:lang="ru"><front><journal-meta><journal-id journal-id-type="publisher-id">cardiovascular</journal-id><journal-title-group><journal-title xml:lang="ru">Кардиоваскулярная терапия и профилактика</journal-title><trans-title-group xml:lang="en"><trans-title>Cardiovascular Therapy and Prevention</trans-title></trans-title-group></journal-title-group><issn pub-type="ppub">1728-8800</issn><issn pub-type="epub">2619-0125</issn><publisher><publisher-name>«SILICEA-POLIGRAF» LLC</publisher-name></publisher></journal-meta><article-meta><article-id pub-id-type="doi">10.15829/1728-8800-2012-6-78-80</article-id><article-id custom-type="elpub" pub-id-type="custom">cardiovascular-2032</article-id><article-categories><subj-group subj-group-type="heading"><subject>Research Article</subject></subj-group><subj-group subj-group-type="section-heading" xml:lang="ru"><subject>МНЕНИЕ ПО ПРОБЛЕМЕ</subject></subj-group><subj-group subj-group-type="section-heading" xml:lang="en"><subject>OPINION ON A PROBLEM</subject></subj-group></article-categories><title-group><article-title>Артериальная гипертензия и ишемическая болезнь сердца: место антагонистов рецепторов ангиотензина II</article-title><trans-title-group xml:lang="en"><trans-title>Arterial hypertension and coronary heart disease: the place of angiotensin II receptor antagonists</trans-title></trans-title-group></title-group><contrib-group><contrib contrib-type="author" corresp="yes"><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Таратухин</surname><given-names>Е. О.</given-names></name><name name-style="western" xml:lang="en"><surname>Taratukhin</surname><given-names>E. O.</given-names></name></name-alternatives><bio xml:lang="ru"/><email xlink:type="simple">cardio03@list.ru</email><xref ref-type="aff" rid="aff-1"/></contrib></contrib-group><aff-alternatives id="aff-1"><aff xml:lang="ru"><institution>Российский национальный исследовательский медицинский университет им. Н. И. Пирогова, Москва</institution></aff><aff xml:lang="en"><institution>N. I. Pirogov Russian National Medical University, Moscow</institution></aff></aff-alternatives><pub-date pub-type="collection"><year>2012</year></pub-date><pub-date pub-type="epub"><day>20</day><month>12</month><year>2012</year></pub-date><volume>11</volume><issue>6</issue><fpage>78</fpage><lpage>80</lpage><permissions><copyright-statement>Copyright &amp;#x00A9; Таратухин Е.О., 2012</copyright-statement><copyright-year>2012</copyright-year><copyright-holder xml:lang="ru">Таратухин Е.О.</copyright-holder><copyright-holder xml:lang="en">Taratukhin E.O.</copyright-holder><license xml:lang="ru" license-type="creative-commons-attribution" xlink:href="https://creativecommons.org/licenses/by/4.0/" xlink:type="simple"><license-p>Данная работа распространяется под лицензией Creative Commons Attribution 4.0.</license-p></license><license xml:lang="en" license-type="creative-commons-attribution" xlink:href="https://creativecommons.org/licenses/by/4.0/" xlink:type="simple"><license-p>This work is licensed under a Creative Commons Attribution 4.0 License.</license-p></license></permissions><self-uri xlink:href="https://cardiovascular.elpub.ru/jour/article/view/2032">https://cardiovascular.elpub.ru/jour/article/view/2032</self-uri><abstract><p>В статье рассматриваются артериальная гипертензия и ишемическая болезнь сердца как состояния, имеющие множество точек соприкосновения их патогенеза. В качестве эффективной терапии этих состояний, способствующей также и профилактике развития осложнений, обсуждаются антагонисты рецепторов типа 1 ангиотензина II. Приводятся современные данные об этих средствах, обсуждаются показания к назначению.</p></abstract><trans-abstract xml:lang="en"><p>The paper considers arterial hypertension and coronary heart disease as pathologies which share multiple pathogenetic mechanisms. The role of angiotensin II receptor antagonists (ARA) in the effective treatment of these diseases and in prevention of their complications is discussed. The modern views on ARA and their indications are presented.</p></trans-abstract><kwd-group xml:lang="ru"><kwd>атеросклероз</kwd><kwd>гемостаз</kwd><kwd>тромбоциты</kwd><kwd>лозартан</kwd></kwd-group><kwd-group xml:lang="en"><kwd>atherosclerosis</kwd><kwd>haemostasis</kwd><kwd>platelets</kwd><kwd>losartan</kwd></kwd-group></article-meta></front><back><ref-list><title>References</title><ref id="cit1"><label>1</label><citation-alternatives><mixed-citation xml:lang="ru">Zhao H, Li M, Wang L, et al. Angiotensin II induces TSLP via an AT1 receptor, promoting Th17 differentiation. Cell Physiol Biochem 2012; 30(6): 1383-97.</mixed-citation><mixed-citation xml:lang="en">Zhao H, Li M, Wang L, et al. Angiotensin II induces TSLP via an AT1 receptor, promoting Th17 differentiation. Cell Physiol Biochem 2012; 30(6): 1383-97.</mixed-citation></citation-alternatives></ref><ref id="cit2"><label>2</label><citation-alternatives><mixed-citation xml:lang="ru">Fang J, Ma L, Zhang S, et al. 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