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<article article-type="research-article" dtd-version="1.3" xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink" xmlns:xsi="http://www.w3.org/2001/XMLSchema-instance" xml:lang="ru"><front><journal-meta><journal-id journal-id-type="publisher-id">cardiovascular</journal-id><journal-title-group><journal-title xml:lang="ru">Кардиоваскулярная терапия и профилактика</journal-title><trans-title-group xml:lang="en"><trans-title>Cardiovascular Therapy and Prevention</trans-title></trans-title-group></journal-title-group><issn pub-type="ppub">1728-8800</issn><issn pub-type="epub">2619-0125</issn><publisher><publisher-name>«SILICEA-POLIGRAF» LLC</publisher-name></publisher></journal-meta><article-meta><article-id pub-id-type="doi">10.15829/1728-8800-2019-1-150-155</article-id><article-id custom-type="elpub" pub-id-type="custom">cardiovascular-2205</article-id><article-categories><subj-group subj-group-type="heading"><subject>Research Article</subject></subj-group><subj-group subj-group-type="section-heading" xml:lang="ru"><subject>МНЕНИЕ ПО ПРОБЛЕМЕ</subject></subj-group><subj-group subj-group-type="section-heading" xml:lang="en"><subject>OPINION ON A PROBLEM</subject></subj-group></article-categories><title-group><article-title>Факторы и механизмы в развитии артериальной гипертензии у больных атеросклерозом артерий нижних конечностей</article-title><trans-title-group xml:lang="en"><trans-title>Factors and mechanisms of arterial hypertension development in patients with atherosclerosis of lower limb arteries</trans-title></trans-title-group></title-group><contrib-group><contrib contrib-type="author" corresp="yes"><contrib-id contrib-id-type="orcid">https://orcid.org/0000-0003-3067-0622</contrib-id><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Евсиков</surname><given-names>Е. М.</given-names></name><name name-style="western" xml:lang="en"><surname>Evsikov</surname><given-names>E. M.</given-names></name></name-alternatives><bio xml:lang="ru"><p>Евсиков Евгений Михайлович — доктор медицинских наук, профессор кафедры госпитальной терапии № 1 лечебного факультета</p><p>Москва</p></bio><bio xml:lang="en"/><email xlink:type="simple">Evsikov@gmail.com</email><xref ref-type="aff" rid="aff-1"/></contrib><contrib contrib-type="author" corresp="yes"><contrib-id contrib-id-type="orcid">https://orcid.org/0000-0003-3568-5065</contrib-id><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Вечорко</surname><given-names>В. И.</given-names></name><name name-style="western" xml:lang="en"><surname>Vechorko</surname><given-names>V. I.</given-names></name></name-alternatives><bio xml:lang="ru"><p>Вечорко Валерий Иванович — кандидат медицинских наук, главный врач</p><p>Москва</p></bio><bio xml:lang="en"/><email xlink:type="simple">Dr.feather@yandex.ru</email><xref ref-type="aff" rid="aff-2"/></contrib><contrib contrib-type="author" corresp="yes"><contrib-id contrib-id-type="orcid">https://orcid.org/0000-0002-2678-6609</contrib-id><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Теплова</surname><given-names>Н. В.</given-names></name><name name-style="western" xml:lang="en"><surname>Teplova</surname><given-names>N. V.</given-names></name></name-alternatives><bio xml:lang="ru"><p>Теплова Наталья Владимировна — доктор медицинских наук, профессор кафедры госпитальной терапии № 1 лечебного факультета</p><p>Москва</p></bio><bio xml:lang="en"/><email xlink:type="simple">teplova_2000@mail.ru</email><xref ref-type="aff" rid="aff-1"/></contrib><contrib contrib-type="author" corresp="yes"><contrib-id contrib-id-type="orcid">https://orcid.org/0000-0003-3320-3149</contrib-id><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Жапуева</surname><given-names>М. Х.</given-names></name><name name-style="western" xml:lang="en"><surname>Zhapueva</surname><given-names>M. H.</given-names></name></name-alternatives><bio xml:lang="ru"><p>Жапуева Мариэтта Хасановна — аспирант кафедры госпитальной терапии</p><p>Москва</p></bio><bio xml:lang="en"/><email xlink:type="simple">Dr.feather@yandex.ru</email><xref ref-type="aff" rid="aff-1"/></contrib><contrib contrib-type="author" corresp="yes"><contrib-id contrib-id-type="orcid">https://orcid.org/0000-0002-1154-6215</contrib-id><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Артамонова</surname><given-names>Н. Г.</given-names></name><name name-style="western" xml:lang="en"><surname>Artamonova</surname><given-names>N. G.</given-names></name></name-alternatives><bio xml:lang="ru"><p>Артамонова Надежда Геннадьевна — аспирант кафедры клиническая фармакология лечебного факультета</p><p>Москва</p></bio><bio xml:lang="en"/><email xlink:type="simple">danielvalmonte@yandex.ru</email><xref ref-type="aff" rid="aff-1"/></contrib></contrib-group><aff-alternatives id="aff-1"><aff xml:lang="ru">ФГБОУ ВО “Российский национальный исследовательский медицинский университет им. Н. И. Пирогова” Минздрава России<country>Россия</country></aff><aff xml:lang="en">Pirogov Russian National Research Medical University<country>Russian Federation</country></aff></aff-alternatives><aff-alternatives id="aff-2"><aff xml:lang="ru">ГБУЗ “ГКБ № 15 им. О. М. Филатова Департамента здравоохранения города Москвы”</aff><aff xml:lang="en">O. M. Filatov Municipal Clinical Hospital № 15</aff></aff-alternatives><pub-date pub-type="collection"><year>2019</year></pub-date><pub-date pub-type="epub"><day>01</day><month>03</month><year>2019</year></pub-date><volume>18</volume><issue>1</issue><fpage>150</fpage><lpage>155</lpage><permissions><copyright-statement>Copyright &amp;#x00A9; Евсиков Е.М., Вечорко В.И., Теплова Н.В., Жапуева М.Х., Артамонова Н.Г., 2019</copyright-statement><copyright-year>2019</copyright-year><copyright-holder xml:lang="ru">Евсиков Е.М., Вечорко В.И., Теплова Н.В., Жапуева М.Х., Артамонова Н.Г.</copyright-holder><copyright-holder xml:lang="en">Evsikov E.M., Vechorko V.I., Teplova N.V., Zhapueva M.H., Artamonova N.G.</copyright-holder><license license-type="creative-commons-attribution" xlink:href="https://creativecommons.org/licenses/by/4.0/" xlink:type="simple"><license-p>This work is licensed under a Creative Commons Attribution 4.0 License.</license-p></license></permissions><self-uri xlink:href="https://cardiovascular.elpub.ru/jour/article/view/2205">https://cardiovascular.elpub.ru/jour/article/view/2205</self-uri><abstract><p>Статья содержит информацию о частоте развития синдрома артериальной гипертензии (АГ), характере и причинах его развития у больных периферическим атеросклерозом. АГ у больных хроническими атеросклеротическими заболеваниями артерий нижних конечностей и острой тромботической окклюзией осложняет течение этой патологии. У большинства больных общепринятой является концепция о связи этих форм АГ с атеросклерозом пораженных почечных артерий. В настоящее время нерешенным остается важный практический вопрос о возможном негативном влиянии интенсивной антигипертензивной терапии со значительным снижением артериального давления и усугубления процессов некробиоза в ишемизированной конечности у пациента с острым артериальным тромбозом.</p></abstract><trans-abstract xml:lang="en"><p>The article contains information about the frequency of development of arterial hypertension (AH), the features and causes of its development in patients with peripheral atherosclerosis. AH in patients with chronic atherosclerotic diseases of lower limb arteries and acute thrombotic occlusion complicates the course of this pathology. In most patients, the opinion that AH associated with atherosclerosis due to affection of renal arteries is generally accepted. Currently, an important practical question remains about the possible negative impact of intensive antihypertensive therapy with a significant reduction in blood pressure and aggravation of necrobiosis processes in the ischemic limb in a patient with acute arterial thrombosis.</p></trans-abstract><kwd-group xml:lang="ru"><kwd>артериальная гипертензия</kwd><kwd>периферический атеросклероз</kwd><kwd>стеноз почечной артерии</kwd></kwd-group><kwd-group xml:lang="en"><kwd>arterial hypertension</kwd><kwd>peripheral atherosclerosis</kwd><kwd>renal artery stenosis</kwd></kwd-group></article-meta></front><back><ref-list><title>References</title><ref id="cit1"><label>1</label><citation-alternatives><mixed-citation xml:lang="ru">The TASC Steering Committee. An update on methods for revascularization and expansion of the TASC lesion classification to include below-the-knee arteries: a supplement to the Inter-Society Consensus for the Management of Peripheral Arterial Disease (TASC II). J Endovasc Ther. 2015;22:657-71. doi:10.1177/1526602815592206.</mixed-citation><mixed-citation xml:lang="en">The TASC Steering Committee. An update on methods for revascularization and expansion of the TASC lesion classification to include below-the-knee arteries: a supplement to the Inter-Society Consensus for the Management of Peripheral Arterial Disease (TASC II). J Endovasc Ther. 2015;22:657-71. doi:10.1177/1526602815592206.</mixed-citation></citation-alternatives></ref><ref id="cit2"><label>2</label><citation-alternatives><mixed-citation xml:lang="ru">Guidelines on the diagnosis and treatment of periferal artery diseases. Eur Heart J. 2011;32:2851-906. doi:10.1093/eurheartj/ehr211.</mixed-citation><mixed-citation xml:lang="en">Guidelines on the diagnosis and treatment of periferal artery diseases. Eur Heart J. 2011;32:2851-906. doi:10.1093/eurheartj/ehr211.</mixed-citation></citation-alternatives></ref><ref id="cit3"><label>3</label><citation-alternatives><mixed-citation xml:lang="ru">Dachun Xu, Jue Li, Liling Zou, et al. Sensitivity and specificity of the anklebrachial index to diagnose peripheral artery disease: a structured review. Vasc Med. 2010;15(5):361-9. doi:10.1177/1358863X10378376.</mixed-citation><mixed-citation xml:lang="en">Dachun Xu, Jue Li, Liling Zou, et al. Sensitivity and specificity of the anklebrachial index to diagnose peripheral artery disease: a structured review. Vasc Med. 2010;15(5):361-9. doi:10.1177/1358863X10378376.</mixed-citation></citation-alternatives></ref><ref id="cit4"><label>4</label><citation-alternatives><mixed-citation xml:lang="ru">Da Silva A, Widmer LK, Ziegler HW, et al. The Basle longitudinal study: report on the relation of initial glucose level to baseline ECG abnormalities, peripheral artery disease, and subsequent mortality. J Chronic Dis. 1979;32:797-803. doi:10.1016/0021-9681(79)90059-6.</mixed-citation><mixed-citation xml:lang="en">Da Silva A, Widmer LK, Ziegler HW, et al. The Basle longitudinal study: report on the relation of initial glucose level to baseline ECG abnormalities, peripheral artery disease, and subsequent mortality. J Chronic Dis. 1979;32:797-803. doi:10.1016/0021-9681(79)90059-6.</mixed-citation></citation-alternatives></ref><ref id="cit5"><label>5</label><citation-alternatives><mixed-citation xml:lang="ru">Norgren L, Hiatt WR, Dormandy JA, et al. Inter-Society Consensus for the Management of Peripheral Arterial Disease (TASC II). J Vasc Surg. 2007;45:5-67. doi:10.1016/j.jvs.2006.12.037.</mixed-citation><mixed-citation xml:lang="en">Norgren L, Hiatt WR, Dormandy JA, et al. Inter-Society Consensus for the Management of Peripheral Arterial Disease (TASC II). J Vasc Surg. 2007;45:5-67. doi:10.1016/j.jvs.2006.12.037.</mixed-citation></citation-alternatives></ref><ref id="cit6"><label>6</label><citation-alternatives><mixed-citation xml:lang="ru">Wong ND, Lopez VA, Allison MA, et al. Abdominal aortic calcium and multisite atherosclerosis. Atherosclerosis. 2011;214(2):436-41. doi:10.1016/j.atherosclerosis.2010.09.011.</mixed-citation><mixed-citation xml:lang="en">Wong ND, Lopez VA, Allison MA, et al. Abdominal aortic calcium and multisite atherosclerosis. Atherosclerosis. 2011;214(2):436-41. doi:10.1016/j.atherosclerosis.2010.09.011.</mixed-citation></citation-alternatives></ref><ref id="cit7"><label>7</label><citation-alternatives><mixed-citation xml:lang="ru">Мельников Н. В., Зелинский В. А., Апресян А. Ю. Предикторы и сывороточные маркеры кальциноза брюшной аорты. Регионарное кровообращение и микроциркуляция. 2012;44(4):12-7. http://www.fesmu.ru/elib/Article.aspx?id=275062.</mixed-citation><mixed-citation xml:lang="en">Melnikov NV, Zelinsky VA, Apresyan AYu. Predictors and serum markers of abdominal aortic calcification. Regional blood circulation and microcirculation. 2012;44(4):12-7. (In Russ.)  http://www.fesmu.ru/elib/Article.aspx?id=275062.</mixed-citation></citation-alternatives></ref><ref id="cit8"><label>8</label><citation-alternatives><mixed-citation xml:lang="ru">Мельников М. В., Зелинский В. А., Жорина А. С. и др. Кальцификация абдоминальной аорты при периферическом атеросклерозе: факторы риска и маркеры. Атеросклероз и дислипидемии. 2014;16(3):33-8. https://cyberleninka.ru/article/n/kaltsifikatsiya-abdominalnoyaorty-pri-perifericheskom-ateroskleroze-faktory-riska-i-markery.</mixed-citation><mixed-citation xml:lang="en">Melnikov MV, Zelinsky VA, Zhorina AS, et al. Calcification of the abdominal aorta in peripheral atherosclerosis: risk factors and markers. Atherosclerosis and dyslipidemia. 2014;16(3):33-8. (In Russ.) https://cyberleninka.ru/article/n/kaltsifikatsiya-abdominalnoyaorty-pri-perifericheskom-ateroskleroze-faktory-riska-i-markery.</mixed-citation></citation-alternatives></ref><ref id="cit9"><label>9</label><citation-alternatives><mixed-citation xml:lang="ru">Greenland P, Alpert JS, Beller GA, et al. 2010 ACCF/AHA guideline for assessment of cardiovascular risk in asymptomatic adults: a report of the American College of Cardiology Foundation/American Heart Association Task Force on Practice Guidelines. Circulation. 2010;122:584-636. doi:10.1161/CIR.0b013e3182051b4c.</mixed-citation><mixed-citation xml:lang="en">Greenland P, Alpert JS, Beller GA, et al. 2010 ACCF/AHA guideline for assessment of cardiovascular risk in asymptomatic adults: a report of the American College of Cardiology Foundation/American Heart Association Task Force on Practice Guidelines. Circulation. 2010;122:584-636. doi:10.1161/CIR.0b013e3182051b4c.</mixed-citation></citation-alternatives></ref><ref id="cit10"><label>10</label><citation-alternatives><mixed-citation xml:lang="ru">Perrone-Filardi P, Achenbach S, Mohlenkamp S, et al. Cardiac computed tomography and myocardial perfusion scintigraphy for risk stratification in asymptomatic individuals without known cardiovascular disease: a position statement of the Working Group on Nuclear Cardiology and Cardiac CT of the European Society of Cardiology. Eur Heart J. 2011;32:1986-93. doi:10.1093/eurheartj/ehq235.</mixed-citation><mixed-citation xml:lang="en">Perrone-Filardi P, Achenbach S, Mohlenkamp S, et al. Cardiac computed tomography and myocardial perfusion scintigraphy for risk stratification in asymptomatic individuals without known cardiovascular disease: a position statement of the Working Group on Nuclear Cardiology and Cardiac CT of the European Society of Cardiology. Eur Heart J. 2011;32:1986-93. doi:10.1093/eurheartj/ehq235.</mixed-citation></citation-alternatives></ref><ref id="cit11"><label>11</label><citation-alternatives><mixed-citation xml:lang="ru">Евсиков Е. М., Теплова Н. В., Майтесян Д. А. и др. Характер артериальной гипертензии у больных атеросклерозом аорты с синдромом острой тромботической окклюзии. Кардиология. 2017;10:89-91. doi:10.15829/1560-4071-2016-9-14-18.</mixed-citation><mixed-citation xml:lang="en">Evsikov EM, Teplova NV, Maytesyan DA, et al. The nature of hypertension in patients with aortic atherosclerosis with acute thrombotic occlusion syndrome. Kardiologiia. 2017;10:89-91. (In Russ.) doi:10.15829/1560-4071-2016-9-14-18.</mixed-citation></citation-alternatives></ref><ref id="cit12"><label>12</label><citation-alternatives><mixed-citation xml:lang="ru">Вечорко В. И., Теплова Н. В., Евсиков Е. М. и др. Частота и причины артериальной гипертензии у больных с острой тромботической окклюзией при атеросклерозе артерий нижних конечностей. В сб. Национальный конгресс терапевтов. Москва, 21-23 ноября 2018;28-9. https://www.rnmot.ru/public/files/events/7/774/Cover_tez_NKT.pdf.</mixed-citation><mixed-citation xml:lang="en">Vechorko VI, Teplova NV, Evsikov EM. The frequency and causes of arterial hypertension in patients with acute thrombotic occlusion in atherosclerosis of lower limb arteries. National Congress of Therapists. Moscow, November 21-23, 2018;28- 9. (In Russ.) https://www.rnmot.ru/public/files/events/7/774/Cover_tez_NKT.pdf.</mixed-citation></citation-alternatives></ref><ref id="cit13"><label>13</label><citation-alternatives><mixed-citation xml:lang="ru">Теплова Н. В., Люсов В. А., Оганов Р. Г. и др. Нефрогенные факторы формирования резистентности к гипотензивной терапии у больных первичной артериальной гипертензией. Рациональная Фармакотерапия в Кардиологии. 2015;6:590-4. doi:10.20996/1819-6446-2015-11-6-590-594.</mixed-citation><mixed-citation xml:lang="en">Teplova NV, Lyusov VA, Oganov RG, et al. Nephrogenic factors for the formation of resistance to antihypertensive therapy in patients with primary arterial hypertension. Rational Pharmacotherapy in Cardiology. 2015;6:590-4. (In Russ.). doi:10.20996/1819-6446-2015-11-6-590-594.</mixed-citation></citation-alternatives></ref><ref id="cit14"><label>14</label><citation-alternatives><mixed-citation xml:lang="ru">Евсиков Е. М., Теплова Н. В., Шарипов Р. А. и др. Характер патологии почек у больных артериальной гипертензией резистентного к терапии течения”. Сборник тезисов Х национального конгресса терапевтов. 2015;62. https://congress.rnmot.ru/public/files/events/2/261/Cover_tez_NKT.pdf.</mixed-citation><mixed-citation xml:lang="en">Evsikov EM, Teplova NV, Sharipov RA, et al. The nature of the pathology of the kidneys in patients with arterial hypertension resistant to therapy course. Collection of theses of the X National Congress of Physicians. 2015; 62. (In Russ.) https://congress.rnmot.ru/public/files/events/2/261/Cover_tez_NKT.pdf.</mixed-citation></citation-alternatives></ref><ref id="cit15"><label>15</label><citation-alternatives><mixed-citation xml:lang="ru">Teplova NV. Resistant forms of primary arterial hypertension. A guide for doctors. Ed. Litterra. M. 2016;110 p. (In Russ.) Теплова Н. В. Резистентные формы первичной артериальной гипертензии. Руководство для врачей. Изд. Литтерра. М. 2016; 110 C. ISBN 978-5-4235-0237-9.</mixed-citation><mixed-citation xml:lang="en">Teplova NV. Resistant forms of primary arterial hypertension. A guide for doctors. Ed. Litterra. M. 2016;110 p. (In Russ.) ISBN 978-5-4235-0237-9.</mixed-citation></citation-alternatives></ref><ref id="cit16"><label>16</label><citation-alternatives><mixed-citation xml:lang="ru">Теплова Н. В., Люсов В. А., Оганов Р. Г. и др. Резистентность к гипотензивной терапии у больных гипертонической болезнью. Значение почечных и гемодинамических факторов. Уральский медицинский журнал. 2015;10:126-32. http://www.urmj.ru/archive/2015/85.</mixed-citation><mixed-citation xml:lang="en">Teplova NV, Lyusov VA, Oganov RG, et al. Resistance to antihypertensive therapy in patients with hypertension. The value of renal and hemodynamic factors. Ural Medical J. 2015;10:126-32. (In Russ.) http://www.urmj.ru/archive/2015/85.</mixed-citation></citation-alternatives></ref><ref id="cit17"><label>17</label><citation-alternatives><mixed-citation xml:lang="ru">Теплова Н. В., Евсиков Е. М., Жапуева М. Х. Состояние гормональной функции и формы патологии щитовидной железы у больных первичной артериальной гипертензией и резистентностью к гипотензивной терапии. Сборник тезисов Российского национального конгресса кардиологов “Российское кардиологическое общество в год борьбы с сердечно-сосудистыми заболеваниями в России” 2015. С.611. http://scardio.ru/content/activities/2015/Tezisy_moscow_2015.pdf.</mixed-citation><mixed-citation xml:lang="en">Teplova NV, Evsikov EM, Zhapueva MKh. Condition of hormonal function and form of thyroid gland pathology in patients with primary arterial hypertension and resistance to antihypertensive therapy. Collection of theses of the Russian National Congress of Cardiology “Russian Cardiological Society in the year of the fight against cardiovascular diseases in Russia” 2015. P.611. (In Russ.) http://scardio.ru/content/activities/2015/Tezisy_moscow_2015.pdf.</mixed-citation></citation-alternatives></ref><ref id="cit18"><label>18</label><citation-alternatives><mixed-citation xml:lang="ru">Bates MC, Campbell JE, Stone et al. Factors affecting long-term survival following renal artery stenting. Catheter Cardiovasc Interv. 2007;69:1037-43. doi:10.1002/ccd.21121.</mixed-citation><mixed-citation xml:lang="en">Bates MC, Campbell JE, Stone et al. Factors affecting long-term survival following renal artery stenting. Catheter Cardiovasc Interv. 2007;69:1037-43. doi:10.1002/ccd.21121.</mixed-citation></citation-alternatives></ref><ref id="cit19"><label>19</label><citation-alternatives><mixed-citation xml:lang="ru">Agel RA, Zoghbi GJ, Baldwin SA, et al. Prevalence of renal artery stenosis in highrisk veterans referred to cardiac catheterization. J Hypertens. 2003;21:1157-62. doi:10.1097/01.hjh.0000059047.65882.00.</mixed-citation><mixed-citation xml:lang="en">Agel RA, Zoghbi GJ, Baldwin SA, et al. Prevalence of renal artery stenosis in highrisk veterans referred to cardiac catheterization. J Hypertens. 2003;21:1157-62. doi:10.1097/01.hjh.0000059047.65882.00.</mixed-citation></citation-alternatives></ref></ref-list><fn-group><fn fn-type="conflict"><p>The authors declare that there are no conflicts of interest present.</p></fn></fn-group></back></article>
