cardiovascularКардиоваскулярная терапия и профилактикаCardiovascular Therapy and Prevention1728-88002619-0125«SILICEA-POLIGRAF» LLC10.15829/1728-8800-2013-4-91-97cardiovascular-221Research ArticleОБЗОРЫREVIEWSИНСУЛИНОРЕЗИСТЕНТНОСТЬ: БЛАГО ИЛИ ЗЛО? МЕХАНИЗМЫ РАЗВИТИЯ И СВЯЗЬ С ВОЗРАСТ-АССОЦИИРОВАННЫМИ ИЗМЕНЕНИЯМИ СОСУДОВINSULIN RESISTANCE: GOOD OR BAD? DEVELOPMENT MECHANISMS AND THE ASSOCIATION WITH AGE-RELATED VASCULAR CHANGESБойцовС. А.BoytsovS. A.

д. м.н., профессор, директор

СтражескоИ. Д.StrazheskoI. D.

в. н.с. отдела комплексного снижения риска неинфекционных заболеваний

Тел.: +7 (985) 210–73–27 

tel.: +7 (985) 210–73–27

istrazhesko@gmail.comАкашеваД. У.AkashevaD. U.

с. н.с. отдела

ДудинскаяЕ. Н.DudinskayaE. N.

с. н.с. отдела

КругликоваА. С.KruglikovaA. S.

н.с. отдела

ТкачеваО. Н.TkachevaO. N.

руководитель отдела

ФГБУ Государственный научно-исследовательский центр профилактической медицины Минздрава России, МоскваState Research Centre for Preventive Medicine, Moscow2013200820131249197Copyright © Бойцов С.А., Стражеско И.Д., Акашева Д.У., Дудинская Е.Н., Кругликова А.С., Ткачева О.Н., 20132013Бойцов С.А., Стражеско И.Д., Акашева Д.У., Дудинская Е.Н., Кругликова А.С., Ткачева О.Н.Boytsov S.A., Strazhesko I.D., Akasheva D.U., Dudinskaya E.N., Kruglikova A.S., Tkacheva O.N.Данная работа распространяется под лицензией Creative Commons Attribution 4.0.This work is licensed under a Creative Commons Attribution 4.0 License.https://cardiovascular.elpub.ru/jour/article/view/221

Обсуждаются механизмы возникновения инсулинорезистентности (ИР), ее роль в развитии основных возраст-ассоциированных изменений сосудов, трансформации старения сосудов в болезнь, вклад ИР в продолжительность жизни. 

The authors discuss the mechanisms of insulin resistance (IR) development; the IR role in the development and progression of the major age-related vascular changes; IR and the transformation of vascular ageing into disease; and IR impact on life expectancy. 

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The authors declare that there are no conflicts of interest present.