cardiovascularКардиоваскулярная терапия и профилактикаCardiovascular Therapy and Prevention1728-88002619-0125«SILICEA-POLIGRAF» LLC10.15829/1728-8800-2020-2318cardiovascular-2318Research ArticleОБЗОРЫREVIEWSПерспективные полимерные соединения мембраны коронарных стент-графтовPromising polymeric compounds for coronary stent graft membranehttps://orcid.org/0000-0002-4405-8904РезвоваМ. А.RezvovaM. A.

Резвова Мария Александровна — младший научный сотрудник лаборатории новых биоматериалов

Кемерово

rezvovamaria@mail.ruhttps://orcid.org/0000-0001-7477-3979ОвчаренкоЕ. А.OvcharenkoE. A.

Овчаренко Евгений Андреевич — кандидат технических наук, заведующий отделом организации инновационных и клинических исследований, заведующий лабораторией 

Кемерово

ov.eugene@gmail.comhttps://orcid.org/0000-0003-3211-1250КлышниковК. Ю.KlyshnikovK. Yu.

Клышников Кирилл Юрьевич — научный сотрудник лаборатории новых биоматериалов

Кемерово

klyshnikovk@gmail.comhttps://orcid.org/0000-0002-6134-7468КудрявцеваЮ. А.KudryavtsevaYu. A.

Кудрявцева Юлия Александровна — заведующий отделом экспериментальной и клинической кардиологии

Кемерово

jackie1970@mail.ruФГБНУ “Научно-исследовательский институт комплексных проблем сердечно-сосудистых заболеваний”Research Institute for Complex Issues of Cardiovascular Diseases20200105202019323182318Copyright © Резвова М.А., Овчаренко Е.А., Клышников К.Ю., Кудрявцева Ю.А., 20202020Резвова М.А., Овчаренко Е.А., Клышников К.Ю., Кудрявцева Ю.А.Rezvova M.A., Ovcharenko E.A., Klyshnikov K.Y., Kudryavtseva Y.A.Данная работа распространяется под лицензией Creative Commons Attribution 4.0.This work is licensed under a Creative Commons Attribution 4.0 License.https://cardiovascular.elpub.ru/jour/article/view/2318

Представлен обзор литературы, определяющий актуальность исследований, связанных с разработкой полимерной мембраны коронарного стент-графта. Новое поколение коронарных стент-графтов призвано увеличить гемосовместимость устройства и обеспечить возможность его доставки в “сложные” участки сосуда. На основании анализа результатов клинического применения коммерчески доступных изделий обозначены три группы перспективных полимеров: биостабильные полиуретаны, криогели на  основе поливинилового спирта, биорезорбируемые композиции на основе полилактида-капролактона и  сополимера молочной и  гликолевой кислот, однако вопрос возможности их применения требует проведения экспериментальных работ.

The literature review discusses the studies on developing the polymer membrane of a coronary stent graft. The new generation of coronary stent grafts is designed to increase the hemocompatibility and ensure its delivery to poorly accessible artery regions. Based on the clinical use results, three groups of promising polymers were identified: biostable polyurethanes, polyvinyl alcohol-based cryogels, bioresorbable compositions based on polylactide-caprolactone and lactic acid-glycolic acid copolymer. However, the possibility of their clinical application requires further experimental studying.

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The authors declare that there are no conflicts of interest present.