cardiovascularКардиоваскулярная терапия и профилактикаCardiovascular Therapy and Prevention1728-88002619-0125«SILICEA-POLIGRAF» LLC10.15829/1728-8800-2013-5-91-96cardiovascular-242Research ArticleОБЗОРЫREVIEWSСЕРДЦЕ И ВОЗРАСТ (ЧАСТЬ III): МЕТОДЫ ВОЗДЕЙСТВИЯ НА ПРОЦЕССЫ СТАРЕНИЯHEART AND AGE (PART III): MODIFYING AGEING PROCESSESАкашеваД. У.AkashevaD. U.

к. м.н., с. н.с. отдела комплексного снижения риска неинфекционных заболеваний

Тел.: 8–903–526–44–81 

tel.: 8–903–526–44–81

dariga-akasheva@yandex.ruПлоховаЕ. В.PlokhovaE. V.

аспирант отдела

СтражескоИ. Д.StrazheskoI. D.

к. м.н., в. н.с. отдела

ДудинскаяЕ. Н.DudinskayaE. N.

к. м.н., н. с. отдела

ТкачеваО. Н.TkachevaO. N.

д. м.н., проф., руководитель отдела

ФГБУ “Государственный научно-исследовательский центр профилактической медицины” Минздрава России, МоскваState Research Centre for Preventive Medicine, Moscow2013201020131259196Copyright © Акашева Д.У., Плохова Е.В., Стражеско И.Д., Дудинская Е.Н., Ткачева О.Н., 20132013Акашева Д.У., Плохова Е.В., Стражеско И.Д., Дудинская Е.Н., Ткачева О.Н.Akasheva D.U., Plokhova E.V., Strazhesko I.D., Dudinskaya E.N., Tkacheva O.N.Данная работа распространяется под лицензией Creative Commons Attribution 4.0.This work is licensed under a Creative Commons Attribution 4.0 License.https://cardiovascular.elpub.ru/jour/article/view/242

В настоящее время наблюдается рост популяции пожилых людей. Возраст является одним из основных факторов риска (ФР) сердечно-сосудистых заболеваний. Тем не менее, основные усилия специалистов профилактической медицины направлены на “модифицируемые” ФР, такие как артериальная гипертония, гиперхолестеринемия, курение и т. д., в то время как возраст рассматривается как не модифицируемый, не поддающийся коррекции ФР. В связи с чем, представляется важным определение механизмов старения сердца и возможных способов влияния на него. Все известные на сегодня методы воздействия на процессы старения сердца не имеют до сих пор клинического применения и требуют дальнейшего изучения. Основные методы воздействия представлены в данной статье. 

The share of elderly people in the general population has been steadily increasing. Age is one of the main risk factors (RFs) of cardiovascular disease. However, the current focus of preventive medicine is on modifiable RFs, such as arterial hypertension, hypercholesterolemia, and smoking, while age is regarded as a nonmodifiable, non-correctable RF. This emphasises the importance of the identification of cardiac ageing mechanisms and potential modifying interventions. All the existing methods which target cardiac ageing processes have not been used in the clinical settings and require further research. The key intervention methods are described in the paper. 

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The authors declare that there are no conflicts of interest present.