cardiovascularКардиоваскулярная терапия и профилактикаCardiovascular Therapy and Prevention1728-88002619-0125«SILICEA-POLIGRAF» LLC10.15829/1728-8800-2015-4-92-95cardiovascular-252Research ArticleОБЗОРЫREVIEWSМИКРОБИОТА КИШЕЧНИКА И ФАКТОРЫ КАРДИОВАСКУЛЯРНОГО РИСКА. ЧАСТЬ 1. МИКРОБИОТА КИШЕЧНИКА, ВОЗРАСТ И ПОЛGUT MICROBIOTA AND CARDIOVASCULAR RISK FACTORS. PART 1. GUT MICROBIOTA, AGE AND SEXКаштановаД. А.KashtanovaD. A.

аспирант отдела изучения процессов старения и профилактики возраст-ассоциированных заболеваний

dr.kashtanova@gmail.comТкачеваО. Н.TkachevaO. N.

д. м.н., профессор, руководитель отдела, зам. директора по научной и лечебной работе

БойцовС. А. А.BoytsovS. A.

д. м.н., профессор, директор

ФГБУ "Государственный научно-исследовательский центр профилактической медицины" Минздрава России. Москва, РоссияFSBI "State Scientific-Prevention Center of the Prevention Medicine" of the Healthcare Ministry. Moscow, Russia2015200820151449295Copyright © Каштанова Д.А., Ткачева О.Н., Бойцов С.А., 20152015Каштанова Д.А., Ткачева О.Н., Бойцов С.А.Kashtanova D.A., Tkacheva O.N., Boytsov S.A.Данная работа распространяется под лицензией Creative Commons Attribution 4.0.This work is licensed under a Creative Commons Attribution 4.0 License.https://cardiovascular.elpub.ru/jour/article/view/252

Накопленный за последнее десятилетие опыт позволяет комплекс­но оценивать здоровье человека, учитывать не только влияние внешних факторов, генетической предрасположенности, но и рас­сматривать организм как "среду обитания" миллиардов микроорга­низмов, которые непрерывно взаимодействуют с организмом хозя­ина. Состав микробиоты кишечника — самого "густонаселенного" органа — как оказалось, взаимосвязан с факторами риска развития сердечно-сосудистых заболеваний. В серии статей будет дано опи­сание новых данных о взаимосвязи микробиоты кишечника и фак­торов кардиоваскулярного риска. В представленной публикации отражены современные представления о взаимосвязи кишечной микробиоты и немодифицируемых факторов риска сердечно-сосу­дистых заболеваний — возраста и пола. Описаны некоторые аспек­ты формирования микробиоты кишечника и внутриутробного раз­вития до раннего детского возраста, изменение микробиоты по мере старения, представлены результаты исследований послед­них лет. Также описаны некоторые сведения о взаимосвязи пола и микробиоты кишечника.

 

The experience of the recent decade has led to ability of complex evaluation of human health, including not only external influences, genetic determinants, but to regard human body as an "environment" for billions of microbes that continuously interact with the host. Microbiota of the gut — the most "inhabitated organ" — is it was discovered, relates to a variety of cardiovascular risk factors. In the series of articles the description of recent data to be provided of the relations of gut microbiota and cardiovascular risk factors. Current article focuses on the recent views on the relation with no modifiable cardiovascular risk factors — sex and age. Some aspects to be described of the microbiota formation since in the womb development and during ageing, the recent results of the studies are described. Also some data on the relation of the sex and gut microbiota is mentioned.

 

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The authors declare that there are no conflicts of interest present.