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<article article-type="research-article" dtd-version="1.3" xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink" xmlns:xsi="http://www.w3.org/2001/XMLSchema-instance" xml:lang="ru"><front><journal-meta><journal-id journal-id-type="publisher-id">cardiovascular</journal-id><journal-title-group><journal-title xml:lang="ru">Кардиоваскулярная терапия и профилактика</journal-title><trans-title-group xml:lang="en"><trans-title>Cardiovascular Therapy and Prevention</trans-title></trans-title-group></journal-title-group><issn pub-type="ppub">1728-8800</issn><issn pub-type="epub">2619-0125</issn><publisher><publisher-name>«SILICEA-POLIGRAF» LLC</publisher-name></publisher></journal-meta><article-meta><article-id pub-id-type="doi">10.15829/1728-8800-2021-2699</article-id><article-id custom-type="elpub" pub-id-type="custom">cardiovascular-2699</article-id><article-categories><subj-group subj-group-type="heading"><subject>Research Article</subject></subj-group><subj-group subj-group-type="section-heading" xml:lang="ru"><subject>МЕТОДЫ ИССЛЕДОВАНИЯ</subject></subj-group><subj-group subj-group-type="section-heading" xml:lang="en"><subject>RESEARCH METHODS</subject></subj-group></article-categories><title-group><article-title>Роль ультразвуковой оценки мышечной массы в диагностике саркопении у пациентов с сердечно-сосудистыми заболеваниями</article-title><trans-title-group xml:lang="en"><trans-title>Ultrasound assessment of muscle mass in the diagnosis of sarcopenia in cardiovascular patients</trans-title></trans-title-group></title-group><contrib-group><contrib contrib-type="author" corresp="yes"><contrib-id contrib-id-type="orcid">https://orcid.org/0000-0002-4155-9332</contrib-id><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Ерохина</surname><given-names>А. С.</given-names></name><name name-style="western" xml:lang="en"><surname>Erokhina</surname><given-names>A. S.</given-names></name></name-alternatives><bio xml:lang="ru"><p>Ерохина Анна Сергеевна — ассистент кафедры общей врачебной практики, поликлинической терапии с курсом гериатрии ФДПО.</p><p>Смоленск.</p><p>Тел.: +7 (960) 579-14-37</p></bio><bio xml:lang="en"><p>Smolensk.</p></bio><email xlink:type="simple">erochina_85@mail.ru</email><xref ref-type="aff" rid="aff-1"/></contrib><contrib contrib-type="author" corresp="yes"><contrib-id contrib-id-type="orcid">https://orcid.org/0000-0003-1853-3844</contrib-id><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Голованова</surname><given-names>Е. Д.</given-names></name><name name-style="western" xml:lang="en"><surname>Golovanova</surname><given-names>E. D.</given-names></name></name-alternatives><bio xml:lang="ru"><p>Голованова Елена Дмитриевна — доктор медицинских наук, профессор, заведующая кафедрой общей врачебной практики, поликлинической терапии с курсом гериатрии ФДПО.</p><p>Смоленск.</p></bio><bio xml:lang="en"><p>Smolensk.</p></bio><email xlink:type="simple">golovanovaed@rambler.ru</email><xref ref-type="aff" rid="aff-1"/></contrib><contrib contrib-type="author" corresp="yes"><contrib-id contrib-id-type="orcid">https://orcid.org/0000-0003-0016-0357</contrib-id><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Милосердов</surname><given-names>М. А.</given-names></name><name name-style="western" xml:lang="en"><surname>Miloserdov</surname><given-names>M. A.</given-names></name></name-alternatives><bio xml:lang="ru"><p>Милосердов Максим Алексеевич — кандидат медицинских наук, ассистент кафедры неврологии и нейрохирургии.</p><p>Смоленск.</p></bio><bio xml:lang="en"><p>Smolensk.</p></bio><email xlink:type="simple">miloserdovmax@mail.ru</email><xref ref-type="aff" rid="aff-1"/></contrib></contrib-group><aff-alternatives id="aff-1"><aff xml:lang="ru"><institution>Смоленский государственный медицинский университет Минздрава России</institution></aff><aff xml:lang="en"><institution>Smolensk State Medical University</institution></aff></aff-alternatives><pub-date pub-type="collection"><year>2021</year></pub-date><pub-date pub-type="epub"><day>11</day><month>02</month><year>2021</year></pub-date><volume>20</volume><issue>3</issue><fpage>2699</fpage><lpage>2699</lpage><permissions><copyright-statement>Copyright &amp;#x00A9; Ерохина А.С., Голованова Е.Д., Милосердов М.А., 2021</copyright-statement><copyright-year>2021</copyright-year><copyright-holder xml:lang="ru">Ерохина А.С., Голованова Е.Д., Милосердов М.А.</copyright-holder><copyright-holder xml:lang="en">Erokhina A.S., Golovanova E.D., Miloserdov M.A.</copyright-holder><license xml:lang="ru" license-type="creative-commons-attribution" xlink:href="https://creativecommons.org/licenses/by/4.0/" xlink:type="simple"><license-p>Данная работа распространяется под лицензией Creative Commons Attribution 4.0.</license-p></license><license xml:lang="en" license-type="creative-commons-attribution" xlink:href="https://creativecommons.org/licenses/by/4.0/" xlink:type="simple"><license-p>This work is licensed under a Creative Commons Attribution 4.0 License.</license-p></license></permissions><self-uri xlink:href="https://cardiovascular.elpub.ru/jour/article/view/2699">https://cardiovascular.elpub.ru/jour/article/view/2699</self-uri><abstract><sec><title>Цель</title><p>Цель. Изучить преимущества оценки мышечной массы с помощью ультразвукового метода в сравнении с антропометрическим для ранней диагностики саркопении у пациентов &gt;45 лет.</p></sec><sec><title>Материал и методы</title><p>Материал и методы. В исследование включено 79 пациентов в возрасте 45-89 лет с ишемической болезнью сердца, артериальной гипертонией, сахарным диабетом 2 типа, хронической сердечной недостаточностью, ожирением 1-3 ст. Диагностика артериальной гипертонии проводилась по рекомендациям Европейского (2018) и Российского (2019) кардиологических обществ; ишемическая болезнь сердца — по клиническим рекомендациям Российского кардиологического общества (2020). Диагностика саркопении проводилась по критериям EWGSOP (European Working Group on Sarcopenia in Older People) 2010, и рекомендациям EWGSOP2 2018. Мышечная масса (ММ) определялась двумя способами: 1 — измерением толщины прямой мышцы живота (ТПМЖ) с помощью ультразвукового метода; и 2 — с помощью измерения мышечной окружности плеча (МОП) и окружности голени (ОГ). Мышечная сила определялась методом кистевой динамометрии. Мышечная функция определялась с помощью теста “скорости ходьбы на 4 м”.</p></sec><sec><title>Результаты</title><p>Результаты. Исследование показало, что у пациентов &gt;45 лет, госпитализированных в отделение неотложной кардиологии, индекс массы тела превышал значение 25 кг/м2 в 88,6% случаев. Частота выявления саркопении различной степени тяжести составила 55,7% (44 случая из 79). Различия в ТПМЖ, МОП и ОГ между группами пациентов без саркопении и с саркопенией были статистически значимы (р&lt;0,001), но были меньше пороговых только для показателя ТПМЖ. Значения ТПМЖ прогрессивно снижались с нарастанием тяжести саркопении; статистически достоверно отличались при всех стадиях от показателя ТПМЖ у пациентов без саркопении (р&lt;0,001) вне зависимости от индекса массы тела. Уменьшение ОГ ниже пороговых значений, определяющих снижение ММ, наблюдалось только при тяжелой саркопении, а МОП — и у мужчин, и у женщин только при тяжелой стадии саркопении. Статистически достоверных отличий для МОП и ОГ в зависимости от стадий саркопении у пациентов с избыточной массой тела и ожирением не выявлено.</p></sec><sec><title>Заключение</title><p>Заключение. Определение ММ путем измерения ТПМЖ с помощью ультразвукового метода в сравнении с антропометрическим позволяет диагностировать саркопению у пациентов &gt;45 лет с сердечно-сосудистыми заболеваниями и ожирением на более ранних стадиях и своевременно рекомендовать профилактические мероприятия.</p></sec></abstract><trans-abstract xml:lang="en"><sec><title>Aim</title><p>Aim. To study the advantages of ultrasound versus anthropometric assessment of muscle mass for early diagnosis of sarcopenia in patients &gt;45 years of age.</p></sec><sec><title>Material and methods</title><p>Material and methods. The study included 79 patients aged 4589 years with coronary artery disease (CAD), hypertension, type 2 diabetes, heart failure, class 1-3 obesity. Diagnosis of hypertension was carried out according to the European (2018) and Russian (2019) guidelines; CAD — according to Russian Society of Cardiology (2020) guidelines. Sarcopenia was diagnosed according to 2010 European Working Group on Sarcopenia in Older People (EWGSOP) criteria and 2018 EWGSOP2 guidelines. Muscle mass (MM) was determined by two methods: 1 — by measuring the rectus abdominis muscle (RAM) thickness using the ultrasound; 2 — by measuring the arm and lower leg circumference. Muscle strength was determined by wrist dynamometer. Muscle function was assessed using the 4-m gait speed test.</p></sec><sec><title>Results</title><p>Results. The study showed that in patients aged &gt;45 years admitted to the emergency cardiology department, the body mass index exceeded 25 kg/m2 in 88,6% of cases. The incidence of sarcopenia of varying severity was 55,7% (n=44). The differences in RAM thickness, arm and lower leg circumference between the groups of patients with/without sarcopenia were significant (p&lt;0,001), but were less than the threshold only for RAM thickness. RAM thickness levels progressively decreased with increasing severity of sarcopenia and significantly differed at all stages compared to patients without sarcopenia (p&lt;0,001), regardless of body mass index. A decrease in lower leg circumference below the threshold values determining a MM decrease was observed only in severe sarcopenia, and arm circumference — in both men and women only in severe sarcopenia. There were no significant differences for arm and lower leg circumference depending on sarcopenia stages in overweight and obese patients.</p></sec><sec><title>Conclusion</title><p>Conclusion. MM assessment by measuring RAM thickness with ultrasound in comparison with the anthropometric method makes it possible to diagnose sarcopenia in patients &gt;45 years of age with cardiovascular diseases and obesity at earlier stages and to promptly recommend preventive measures.</p></sec></trans-abstract><kwd-group xml:lang="ru"><kwd>саркопения</kwd><kwd>антропометрия</kwd><kwd>ультразвуковая оценка мышечной массы</kwd><kwd>толщина прямой мышцы живота</kwd></kwd-group><kwd-group xml:lang="en"><kwd>sarcopenia</kwd><kwd>anthropometry</kwd><kwd>muscle mass ultrasound assessment</kwd><kwd>rectus abdominis muscle thickness</kwd></kwd-group><funding-group><funding-statement xml:lang="ru">Работа выполняется в рамках государственного задания Минздрава России № АААА-А-19-119012190133-7 от 9.01.2019.</funding-statement><funding-statement xml:lang="en">The work was carried out within the state assignment of the Ministry of Health of Russia № АААА-А-19-119012190133-7 dated January 9, 2019.</funding-statement></funding-group></article-meta></front><back><ref-list><title>References</title><ref id="cit1"><label>1</label><citation-alternatives><mixed-citation xml:lang="ru">Cruz-Jentoft AJ, Baeyens JP, Bauer JM, et al. 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