cardiovascularКардиоваскулярная терапия и профилактикаCardiovascular Therapy and Prevention1728-88002619-0125«SILICEA-POLIGRAF» LLC10.15829/1728-8800-2021-2746cardiovascular-2746Research ArticleОБЗОРЫ ЛИТЕРАТУРЫREVIEW ARTICLESАнтропометрические индексы ожирения и кардиометаболический риск: есть ли связь?Anthropometric indices obesity and cardiometabolic risk: is there a link?https://orcid.org/0000-0001-7834-2359СваровскаяА. В.SvarovskayaA. V.

Алла Владимировна Сваровская — доктор медицинских наук, старший научный сотрудник отделения патологии миокарда

Томск. Тел.: +7 (906) 957-53-85

Svarovskaya Alla V. - РhD, Senior Researcher, Department of Myocardial Pathology

kuznecova-alla@list.ruhttps://orcid.org/0000-0002-9488-6900ГарганееваА. А.GarganeevaA. A.

Алла Анатольевна Гарганеева - доктор медицинских наук, профессор, зав. отделением патологии миокарда.

Томск

Garganeeva Alla A. - Professor, PhD, Head of Department of Myocardial Pathology

aagg55@mail.ruНаучно-исследовательский институт кардиологии, Томский национальный исследовательский медицинский центр , Российская академия наукCardiology Research Institute, Tomsk National Research Medical Centre, Russian Academy of Sciences20211707202120427462746Copyright © Сваровская А.В., Гарганеева А.А., 20212021Сваровская А.В., Гарганеева А.А.Svarovskaya A.V., Garganeeva A.A.Данная работа распространяется под лицензией Creative Commons Attribution 4.0.This work is licensed under a Creative Commons Attribution 4.0 License.https://cardiovascular.elpub.ru/jour/article/view/2746

Жировая ткань в настоящее время рассматривается в качестве ключевого органа в отношении избыточного количества пищевых липидов, которые определяют, будет ли организм поддерживать нормальный гомеостаз или будут возникать состояния воспаления, инсулинорезистентности. В последние годы в литературе возросло количество информации об относительно новых прогностических моделях — индексе висцерального ожирения и индексе накопления липидов. Цель обзора — критический анализ результатов исследований по изучению взаимосвязи различных индексов ожирения и кардиометаболического риска. Проанализированы 105 источников литературы, из них 53 источника исключены, т.к. интересующие процессы не были подробно описаны или включали оценку взаимосвязей различных индексов ожирения с метаболическими параметрами. Полученные результаты свидетельствуют о целесообразности использования новых индексов ожирения, которые обладают хорошей предиктивной способностью, и достаточно просты и удобны в применении. Необходимо использовать дополнительные методы антропометрического и клинического обследования с целью оценки метаболического фенотипа ожирения, что позволит стратифицировать пациентов по уровню кардиометаболического риска для последующего формирования комплекса профилактических мероприятий, направленных на улучшение диагностики и стратегии лечения.

Adipose tissue is currently regarded as a key organ for excess dietary lipids, which determine whether the body will maintain normal homeostasis or whether inflammation and insulin resistance will develop. In recent years, there is more information about novel prognostic models — the visceral adiposity index and the lipid accumulation product. The aim of this review was to analyze the results of studies examining the relationship between various indices of obesity and cardiometabolic risk. We analyzed 105 literature sources, 53 of which were ruled out, becausethe processes of interest were not described in detail or included anassessment of the relationship of various obesity indices with metabolic parameters. The results obtained indicate the advisability of using novel obesity indices, which have a good predictive ability and are simple and convenient to use. It is necessary to use additional methods of anthropometric and clinical examination in order to assess the metabolic phenotype of obesity, which will make it possible to stratify patients by the level of cardiometabolic risk.

ожирениеабдоминальное ожирениеиндекс массы телаокружность талииотношение окружности талии к окружности бедеротношение окружности талии к ростуиндекс накопления липидовиндекс висцерального ожирениobesityabdominal obesitybody mass indexwaist circumferencewaist-to-hip ratiowaist-to-height ratiolipid accumulation productvisceral obesity indexСтатья выполнена в рамках темы прикладных научных исследований по государственному заданию AAAA-A20-120041090007-8The paper was made within the state assignment AAAA-A20-120041090007-8ReferencesNdumele CE, Matsushita K, Lazo M, et al. Obesity and subtypes of incident cardiovascular disease. J Am Heart Assoc. 2016;5:334-9. doi:10.1161/JAHA.116.003921.Ndumele CE, Matsushita K, Lazo M, et al. Obesity and subtypes of incident cardiovascular disease. J Am Heart Assoc. 2016;5:334-9. doi:10.1161/JAHA.116.003921.Козупеева Д. А., Мустафина С. В. Метаболически здоровое ожирение и атеросклероз-ассоциированные заболевания. 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The authors declare that there are no conflicts of interest present.