cardiovascularКардиоваскулярная терапия и профилактикаCardiovascular Therapy and Prevention1728-88002619-0125«SILICEA-POLIGRAF» LLC10.15829/1728-8800-2021-2787cardiovascular-2787Research ArticleОБЗОРЫ ЛИТЕРАТУРЫREVIEW ARTICLESОстеосаркопеническое ожирение у пациентов с сердечно-сосудистыми заболеваниями. Спорные и нерешенные вопросыOsteosarcopenic obesity in cardiovascular patients. Controversial and open issueshttps://orcid.org/0000-0003-2384-5682КривошаповаК. Е.KrivoshapovaK. E.

Кристина Евгеньевна Кривошапова — кандидат медицинских наук, научный сотрудник лаборатории коморбидности при сердечно-сосудистых заболеваниях.

Кемерово

Kemerovo

ya.kristi89@yandex.ruhttps://orcid.org/0000-0003-3970-4294МасенкоВ. Л.MasenkoV. L.

Владислава Леонидовна Масенко — кандидат медицинских наук, научный сотрудник лаборатории лучевых методов диагностики.

Кемерово

Kemerovo

alenushka_007@bk.ruhttps://orcid.org/0000-0002-3023-6239БаздыревЕ. Дм.BazdyrevE. D.

Евгений Дмитриевич Баздырев — доктор медицинских наук, зав. лабораторией эпидемиологии сердечно-сосудистых заболеваний, отдела оптимизации медицинской помощи при сердечно-сосудистых заболеваниях.

Кемерово

Kemerovo

edb624@mail.ruhttps://orcid.org/0000-0002-4642-3610БарбарашО. Л.BarbarashO. L.

Ольга Леонидовна Барбараш — доктор медицинских наук, профессор, член-корр. РАН, директор.

Кемерово

Kemerovo

olb61@mail.ruФГБНУ Научно-исследовательский институт комплексных проблем сердечно-сосудистых заболеванийResearch Institute for Complex Issues of Cardiovascular Diseases20211510202120627872787Copyright © Кривошапова К.Е., Масенко В.Л., Баздырев Е.Д., Барбараш О.Л., 20212021Кривошапова К.Е., Масенко В.Л., Баздырев Е.Д., Барбараш О.Л.Krivoshapova K.E., Masenko V.L., Bazdyrev E.D., Barbarash O.L.Данная работа распространяется под лицензией Creative Commons Attribution 4.0.This work is licensed under a Creative Commons Attribution 4.0 License.https://cardiovascular.elpub.ru/jour/article/view/2787

Читайте статью: “Инфламмейджинг в патогенезе хронических неинфекционных заболеваний”, Ким О. Т. в разделе Мнение приглашенного редактора, стр. 54-55

Изучение проблемы остеосаркопенического ожирения (ОСО) у больных сердечно-сосудистыми заболеваниями (ССЗ) в последние годы вызвало в научном сообществе дискуссию, касающуюся вопросов общности патогенеза атеросклероза, ожирения, прогрессирующей потери скелетной и мышечной массы. Являются ли эти процессы независимыми возраст-ассоциированными состояниями или коморбидной патологией, объединяемой общими звеньями патогенеза? Цель настоящего обзора — проанализировать результаты исследований, затрагивающих особенности течения ОСО у пациентов с ССЗ. Поиск источников литературы проводился с помощью различных баз данных: PubMed, Clinical Trials, академия Google, www.elibrary.ru (электронной библиотеки научных публикаций). На основании проведенного анализа были описаны современные представления об этиологии, эпидемиологии и патогенетических особенностях развития ОСО у пациентов пожилого и старческого возраста с атеросклерозом. Авторы пришли к выво-ду, что отсутствие стандарта диагностики этой патологии и настороженности специалистов в отношении ОСО при рутинном обсле-довании является одной из основных причин недостаточного его выявления в когорте пожилых пациентов с ССЗ. Результаты проведенных исследований позволяют рассматривать ОСО и атеросклеротические изменения как единое звено сердечно-сосудисто-го континуума. Устранение отрицательного влияния хронического воспаления на организм человека должно рассматриваться в качестве ключевого механизма в лечении ОСО и атеросклероза. Но необходимо проведение дополнительных исследований в этой области.

See “Inflammaging in the pathogenesis of chronic non-communicable diseases”, Kim O. T. in Opinion of invited editor, pp. 54-55.

The study of osteosarcopenic obesity (OSO) in patients with cardiovascular diseases (CVDs) in recent years has caused a dis-cussion on common pathogenesis of atherosclerosis, obesity, progressive loss of skeletal and muscle mass. Are these processes independent age-related conditions or comorbidities with common links of pathogenesis? The aim of this review was to analyze studies on OSO in patients with CVDs. We used following electronic databases: PubMed, Clinical Trials, Google Scholar, www.elibrary.ru. Based on this analysis, modern ideas on the etiology, epidemiology and pathogenesis of OSO in elderly and senile patients with atherosclerosis were described. The authors concluded that absence of standards for OSO diagnosis and inadequate clinical suspicion of specialists during routine examination is one of the main causes of its insufficient detection in elderly patients with CVDs. The results of analyzed studies allow us to consider the OSO and atherosclerotic changes as a single link of cardiovascular continuum. Eliminating the negative effect of chronic inflammation on human body should be considered as a key mechanism in the treatment of OSO and atherosclerosis. However, more research is needed in this area.

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The authors declare that there are no conflicts of interest present.