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<article article-type="research-article" dtd-version="1.3" xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink" xmlns:xsi="http://www.w3.org/2001/XMLSchema-instance" xml:lang="ru"><front><journal-meta><journal-id journal-id-type="publisher-id">cardiovascular</journal-id><journal-title-group><journal-title xml:lang="ru">Кардиоваскулярная терапия и профилактика</journal-title><trans-title-group xml:lang="en"><trans-title>Cardiovascular Therapy and Prevention</trans-title></trans-title-group></journal-title-group><issn pub-type="ppub">1728-8800</issn><issn pub-type="epub">2619-0125</issn><publisher><publisher-name>«SILICEA-POLIGRAF» LLC</publisher-name></publisher></journal-meta><article-meta><article-id pub-id-type="doi">10.15829/1728-8800-2021-2845</article-id><article-id custom-type="elpub" pub-id-type="custom">cardiovascular-2845</article-id><article-categories><subj-group subj-group-type="heading"><subject>Research Article</subject></subj-group><subj-group subj-group-type="section-heading" xml:lang="ru"><subject>ОБЗОРЫ ЛИТЕРАТУРЫ</subject></subj-group><subj-group subj-group-type="section-heading" xml:lang="en"><subject>REVIEW ARTICLES</subject></subj-group></article-categories><title-group><article-title>Гиперсимпатикотония в патогенезе артериальной гипертонии и методы ее коррекции. Часть II</article-title><trans-title-group xml:lang="en"><trans-title>Sympathetic hyperactivity in patients with hypertension: pathogenesis and treatment. Part II</trans-title></trans-title-group></title-group><contrib-group><contrib contrib-type="author" corresp="yes"><contrib-id contrib-id-type="orcid">https://orcid.org/0000-0002-6104-8388</contrib-id><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Сафарян</surname><given-names>А. С.</given-names></name><name name-style="western" xml:lang="en"><surname>Safaryan</surname><given-names>A. S.</given-names></name></name-alternatives><bio xml:lang="ru"><p>Кандидат медицинских наук, ведущий научный сотрудник отдела профилактики метаболических нарушений.</p><p>Москва, Тел.: +7 (903) 971-02-20</p></bio><bio xml:lang="en"><p>Moscow, Тел.: +7 (903) 971-02-20</p></bio><email xlink:type="simple">anush70@list.ru</email><xref ref-type="aff" rid="aff-1"/></contrib><contrib contrib-type="author" corresp="yes"><contrib-id contrib-id-type="orcid">https://orcid.org/0000-0002-5265-3164</contrib-id><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Небиеридзе</surname><given-names>Д. В.</given-names></name><name name-style="western" xml:lang="en"><surname>Nebieridze</surname><given-names>D. V.</given-names></name></name-alternatives><bio xml:lang="ru"><p>Доктор медицинских наук, руководитель отдела профилактики метаболических нарушений.</p><p>Москва</p></bio><bio xml:lang="en"><p>Moscow</p></bio><email xlink:type="simple">DNeberidze@gnicpm.ru</email><xref ref-type="aff" rid="aff-1"/></contrib></contrib-group><aff-alternatives id="aff-1"><aff xml:lang="ru"><institution>ФГБУ Национальный медицинский исследовательский центр терапии и профилактической медицины Минздрава России</institution></aff><aff xml:lang="en"><institution>National Medical Research Center for Therapy and Preventive Medicine</institution></aff></aff-alternatives><pub-date pub-type="collection"><year>2021</year></pub-date><pub-date pub-type="epub"><day>16</day><month>10</month><year>2021</year></pub-date><volume>20</volume><issue>6</issue><fpage>2845</fpage><lpage>2845</lpage><permissions><copyright-statement>Copyright &amp;#x00A9; Сафарян А.С., Небиеридзе Д.В., 2021</copyright-statement><copyright-year>2021</copyright-year><copyright-holder xml:lang="ru">Сафарян А.С., Небиеридзе Д.В.</copyright-holder><copyright-holder xml:lang="en">Safaryan A.S., Nebieridze D.V.</copyright-holder><license xml:lang="ru" license-type="creative-commons-attribution" xlink:href="https://creativecommons.org/licenses/by/4.0/" xlink:type="simple"><license-p>Данная работа распространяется под лицензией Creative Commons Attribution 4.0.</license-p></license><license xml:lang="en" license-type="creative-commons-attribution" xlink:href="https://creativecommons.org/licenses/by/4.0/" xlink:type="simple"><license-p>This work is licensed under a Creative Commons Attribution 4.0 License.</license-p></license></permissions><self-uri xlink:href="https://cardiovascular.elpub.ru/jour/article/view/2845">https://cardiovascular.elpub.ru/jour/article/view/2845</self-uri><abstract><p>Во второй части обзора рассмотрены различные классы препаратов, которые влияют на артериальное давление при повышении тонуса симпатической нервной системы. Обсуждаются дополнительные возможности того, как уменьшить негативное влияние активности симпатической нервной системы на сердечно-сосудис-тую систему и улучшить прогноз.</p></abstract><trans-abstract xml:lang="en"><p>The second part of the review considers different classes of drugs affecting blood pressure in increased activity of the sympathetic nervous system. Additional possibilities are discussed on how to reduce the negative effect of sympathetic hyperactivity on cardiovascular system and improve the prognosis.</p></trans-abstract><kwd-group xml:lang="ru"><kwd>артериальная гипертония</kwd><kwd>артериальное давление</kwd><kwd>вегетативная нервная система</kwd><kwd>симпатическая нервная система</kwd><kwd>ангиотензин II</kwd><kwd>норадреналин</kwd><kwd>сердечно-сосудистая система</kwd><kwd>медикаментозные воздействия</kwd></kwd-group><kwd-group xml:lang="en"><kwd>hypertension</kwd><kwd>blood pressure</kwd><kwd>autonomic nervous system</kwd><kwd>sympathetic nervous system</kwd><kwd>angiotensin II</kwd><kwd>norepinephrine</kwd><kwd>cardio-vascular system</kwd><kwd>drug effects</kwd></kwd-group></article-meta></front><back><ref-list><title>References</title><ref id="cit1"><label>1</label><citation-alternatives><mixed-citation xml:lang="ru">Сафарян А. С., Саргсян В. Д. 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