cardiovascularКардиоваскулярная терапия и профилактикаCardiovascular Therapy and Prevention1728-88002619-0125«SILICEA-POLIGRAF» LLC10.15829/1728-8800-2021-2860cardiovascular-2860Research ArticleОБЗОРЫ ЛИТЕРАТУРЫREVIEW ARTICLESБурая жировая ткань — новая мишень борьбы с ожирением?Is brown adipose tissue a new target for obesity therapy?https://orcid.org/0000-0002-4453-8430ДрапкинаО. М.DrapkinaO. M.

Драпкина Оксана Михайловна — доктор медицинских наук, профессор, член-корреспондент РАН, директор.

Москва.

Moscow.

drapkina@bk.ruhttps://orcid.org/0000-0002-0332-7696КимО. Т.KimO. T.

Ким Ольга Трофимовна — младший научный сотрудник отдела фундаментальных и прикладных аспектов ожирения.

Москва.

Тел.: +7 (901) 507-49-87

Moscow.

Tel.: +7 (901) 507-49-87

olgakimt06@gmail.comНациональный научно-исследовательский центр терапии и профилактической медицины Минздрава РоссииNational Research Center for Therapy and Preventive Medicine20210407202120528602860Copyright © Драпкина О.М., Ким О.Т., 20212021Драпкина О.М., Ким О.Т.Drapkina O.M., Kim O.T.Данная работа распространяется под лицензией Creative Commons Attribution 4.0.This work is licensed under a Creative Commons Attribution 4.0 License.https://cardiovascular.elpub.ru/jour/article/view/2860

Стремительное увеличение распространенности ожирения и ассоциированных с ним заболеваний поставило перед исследователями задачу поиска новых эффективных терапевтических мишеней. В последнее время бурая жировая ткань находится в центре внимания как потенциальный объект для лечения метаболических заболеваний из-за способности увеличивать расход энергии и регулировать гомеостаз глюкозы и липидов. В обзоре представлены последние данные о подходах, направленных на активацию и расширение бурой жировой ткани с целью борьбы с ожирением.

The rapid increase in the prevalence of obesity and related diseases has prompted researchers to seek novel effective therapeutic targets. Recently, brown adipose tissue has been in the spotlight as a potential target for treatment of metabolic diseases due to its ability to increase energy expenditure and regulate glucose and lipid homeostasis. The review presents the latest data on approaches aimed at activating and expanding brown adipose tissue in order to combat obesity.

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The authors declare that there are no conflicts of interest present.