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<article article-type="research-article" dtd-version="1.3" xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink" xmlns:xsi="http://www.w3.org/2001/XMLSchema-instance" xml:lang="ru"><front><journal-meta><journal-id journal-id-type="publisher-id">cardiovascular</journal-id><journal-title-group><journal-title xml:lang="ru">Кардиоваскулярная терапия и профилактика</journal-title><trans-title-group xml:lang="en"><trans-title>Cardiovascular Therapy and Prevention</trans-title></trans-title-group></journal-title-group><issn pub-type="ppub">1728-8800</issn><issn pub-type="epub">2619-0125</issn><publisher><publisher-name>«SILICEA-POLIGRAF» LLC</publisher-name></publisher></journal-meta><article-meta><article-id pub-id-type="doi">10.15829/1728-8800-2021-2865</article-id><article-id custom-type="elpub" pub-id-type="custom">cardiovascular-2865</article-id><article-categories><subj-group subj-group-type="heading"><subject>Research Article</subject></subj-group><subj-group subj-group-type="section-heading" xml:lang="ru"><subject>ЭПИДЕМИОЛОГИЯ И ПРОФИЛАКТИКА</subject></subj-group></article-categories><title-group><article-title>Распространенность сочетания артериальной гипертонии и дислипидемии среди взрослого населения крупного Восточносибирского региона</article-title><trans-title-group xml:lang="en"><trans-title>Prevalence of a combination of hypertension and dyslipidemia among the adult population of a large East Siberian region</trans-title></trans-title-group></title-group><contrib-group><contrib contrib-type="author" corresp="yes"><contrib-id contrib-id-type="orcid">https://orcid.org/0000-0002-4621-1618</contrib-id><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Гринштейн</surname><given-names>Ю. И.</given-names></name><name name-style="western" xml:lang="en"><surname>Grinshtein</surname><given-names>Yu. I.</given-names></name></name-alternatives><bio xml:lang="ru"><p>Юрий Исаевич Гринштейн — доктор медицинских наук, профессор, зав. кафедрой терапии ИПО</p></bio><email xlink:type="simple">grinst.yi@gmail.com</email><xref ref-type="aff" rid="aff-1"/></contrib><contrib contrib-type="author" corresp="yes"><contrib-id contrib-id-type="orcid">https://orcid.org/0000-0001-8002-2362</contrib-id><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Шабалин</surname><given-names>В. В.</given-names></name><name name-style="western" xml:lang="en"><surname>Shabalin</surname><given-names>V. V.</given-names></name></name-alternatives><bio xml:lang="ru"><p>Владимир Викторович Шабалин — кандидат медицинских наук, доцент кафедры терапии ИПО</p><p>Красноярск.Тел.: +7 (913) 567-91-58</p></bio><email xlink:type="simple">vlshabalin@yandex.ry</email><xref ref-type="aff" rid="aff-1"/></contrib><contrib contrib-type="author" corresp="yes"><contrib-id contrib-id-type="orcid">https://orcid.org/0000-0003-1753-6816</contrib-id><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Руф</surname><given-names>Р. Р.</given-names></name><name name-style="western" xml:lang="en"><surname>Ruf</surname><given-names>R. R.</given-names></name></name-alternatives><bio xml:lang="ru"><p>Руслан Райнгольдович Руф — кандидат медицинских наук, ассистент кафедры терапии ИПО</p></bio><email xlink:type="simple">kromsolog@gmail.com</email><xref ref-type="aff" rid="aff-1"/></contrib><contrib contrib-type="author" corresp="yes"><contrib-id contrib-id-type="orcid">https://orcid.org/0000-0003-2087-6483</contrib-id><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Шальнова</surname><given-names>С. А.</given-names></name><name name-style="western" xml:lang="en"><surname>Shalnova</surname><given-names>S. A.</given-names></name></name-alternatives><bio xml:lang="ru"><p>Светлана Анатольевна Шальнова — доктор медицинских наук, профессор, руководитель отдела эпидемиологии хронических неинфекционных заболеваний.</p><p>Москва</p></bio><bio xml:lang="en"><p>Moscow</p></bio><email xlink:type="simple">svetlanashalnova@yandex.ru</email><xref ref-type="aff" rid="aff-2"/></contrib><contrib contrib-type="author" corresp="yes"><contrib-id contrib-id-type="orcid">https://orcid.org/0000-0002-4453-8430</contrib-id><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Драпкина</surname><given-names>О. М.</given-names></name><name name-style="western" xml:lang="en"><surname>Drapkina</surname><given-names>O. M.</given-names></name></name-alternatives><bio xml:lang="ru"><p>Оксана Михайловна Драпкина — доктор медицинских наук, профессор, член-корр. РАН, директор.</p><p>Москва</p></bio><bio xml:lang="en"><p>Moscow</p></bio><email xlink:type="simple">drapkina@bk.ru</email><xref ref-type="aff" rid="aff-2"/></contrib></contrib-group><aff-alternatives id="aff-1"><aff xml:lang="ru"><institution>ФГБОУ ВО Красноярский государственный медицинский университет им. проф. В.Ф. Войно-Ясенецкого Минздрава России</institution></aff><aff xml:lang="en"><institution>V.F. Voino-Yasenetsky Krasnoyarsk State Medical University</institution></aff></aff-alternatives><aff-alternatives id="aff-2"><aff xml:lang="ru"><institution>ФГБУ Национальный медицинский исследовательский центр терапии и профилактической медицины  Минздрава России</institution></aff><aff xml:lang="en"><institution>National Medical Research Center for Therapy and Preventive Medicine</institution></aff></aff-alternatives><pub-date pub-type="collection"><year>2021</year></pub-date><pub-date pub-type="epub"><day>14</day><month>07</month><year>2021</year></pub-date><volume>20</volume><issue>4</issue><fpage>2865</fpage><lpage>2865</lpage><permissions><copyright-statement>Copyright &amp;#x00A9; Гринштейн Ю.И., Шабалин В.В., Руф Р.Р., Шальнова С.А., Драпкина О.М., 2021</copyright-statement><copyright-year>2021</copyright-year><copyright-holder xml:lang="ru">Гринштейн Ю.И., Шабалин В.В., Руф Р.Р., Шальнова С.А., Драпкина О.М.</copyright-holder><copyright-holder xml:lang="en">Grinshtein Y.I., Shabalin V.V., Ruf R.R., Shalnova S.A., Drapkina O.M.</copyright-holder><license xml:lang="ru" license-type="creative-commons-attribution" xlink:href="https://creativecommons.org/licenses/by/4.0/" xlink:type="simple"><license-p>Данная работа распространяется под лицензией Creative Commons Attribution 4.0.</license-p></license><license xml:lang="en" license-type="creative-commons-attribution" xlink:href="https://creativecommons.org/licenses/by/4.0/" xlink:type="simple"><license-p>This work is licensed under a Creative Commons Attribution 4.0 License.</license-p></license></permissions><self-uri xlink:href="https://cardiovascular.elpub.ru/jour/article/view/2865">https://cardiovascular.elpub.ru/jour/article/view/2865</self-uri><abstract><sec><title>Цель</title><p>Цель. Изучить распространенность сочетания двух важнейших факторов сердечно-сосудистого риска — артериальной гипертонии (АГ) и нарушений липидного обмена — среди населения Красноярского края в целом, а также среди мужчин и женщин в различных возрастных группах.</p></sec><sec><title>Материал и методы</title><p>Материал и методы. Проанализированы данные обследования на случайной репрезентативной выборке из 1603 жителей города Красноярска и Березовского сельского района в возрасте 25-64 лет в рамках общероссийского эпидемиологического исследования ЭССЕ-РФ (Эпидемиология сердечно-сосудистых заболеваний в различных регионах Российской Федерации). Статистическая обработка выполнена в программах IBM SPSS 22 и Microsoft Office Excel 2007. Вычислен процент лиц, имеющих АГ и дислипидемию (ДЛП), от общего числа обследованных и 95% доверительные интервалы. Двусторонняя статистическая значимость различий распространенности сочетания АГ и ДЛП проверена по критерию χ2 с поправкой Йетса. Различия считались значимыми при p ≤0,05.</p></sec><sec><title>Результаты</title><p>Результаты. Сочетание АГ и любой ДЛП составило 40% всех наблюдений, АГ + гиперхолестеринемия — 31,6%, АГ + повышенный уровень холестерина (ХС) липопротеинов низкой плотности (ЛНП) — 32,3%, АГ + гипертриглицеридемия — 16,4%, АГ + сниженный уровень ХС липопротеинов высокой плотности — 10,8% и имело свойство нарастать с возрастом. Распространенность комбинации АГ с гиперхолестеринемий, с повышенным уровнем ХС ЛНП, а также АГ с любой ДЛП у женщин в возрастной группе 55-64 лет оказалась значимо выше аналогичных показателей у мужчин.</p></sec><sec><title>Заключение</title><p>Заключение. Распространённость комбинации АГ с любым видом ДЛП в Красноярском крае среди взрослого населения 25-64 лет составила 40% и увеличивалась с возрастом. У женщин в возрастной группе 55-64 лет распространенность сочетания АГ с гиперхолестеринемий, с повышенным уровнем ХС ЛНП, а также АГ с любой ДЛП оказалась значимо выше аналогичных показателей у мужчин.</p></sec></abstract><trans-abstract xml:lang="en"><sec><title>Aim</title><p>Aim. To study the prevalence of a combination of two major cardiovascular risk factors, hypertension (HTN) and lipid metabolism disorders, among the Krasnoyarsk Krai population as a whole, as well as among men and women in different age groups.</p></sec><sec><title>Material and methods</title><p>Material and methods. We analyzed the data from a random representative sample of 1603 residents of the Krasnoyarsk city and Berezovsky district aged 25-64 years within the ESSE-RF epidemiological study. Statistical processing was performed using IBM</p><p>SPSS 22 and Microsoft Office Excel 2007. The proportion of people with hypertension and dyslipidemia and 95% confidence intervals was calculated. The significance of differences in the prevalence of hypertension and dyslipidemia was tested using the chi-squared test with Yates’ correction. Differences were considered significant at p≤0,05.</p></sec><sec><title>Results</title><p>Results. The prevalence of a combination of HTN and any dyslipidemia was 40%, HTN + hypercholesterolemia — 31,6%, HTN + high low density lipoprotein cholesterol (LDL-C) — 32,3%, HTN + hypertriglyceridemia — 16,4%, HTN + reduced high density lipoprotein cholesterol (HDL-C) — 10,8%. This characteristic increased with age. The prevalence of a combination of HTN with hypercholesterolemia, with an increased LDL-C level, as well as HTN with any dyslipidemia in women aged 55-64 years was significantly higher than in men.</p></sec><sec><title>Conclusion</title><p>Conclusion. The prevalence of a combination of HTN with any dyslipidemia in the Krasnoyarsk Krai among the adult population aged 25-64 years was 40% and increased with age. In women aged 55-64 years, the prevalence of a combination of HTN with hypercholesterolemia, with an increased LDL-C level, as well as HTN with any dyslipidemia was significantly higher than in men.</p></sec></trans-abstract><kwd-group xml:lang="ru"><kwd>артериальная гипертония</kwd><kwd>дислипидемия</kwd><kwd>липитензия</kwd><kwd>сердечно-сосудистые факторы риска</kwd><kwd>эпидемиология</kwd></kwd-group><kwd-group xml:lang="en"><kwd>hypertension</kwd><kwd>dyslipidemia</kwd><kwd>lipitension</kwd><kwd>cardiovascular risk factors</kwd><kwd>epidemiology</kwd></kwd-group></article-meta></front><back><ref-list><title>References</title><ref id="cit1"><label>1</label><citation-alternatives><mixed-citation xml:lang="ru">Griswold MG, Fullman N, Hawley C, et al. Alcohol use and burden for 195 countries and territories, 1990-2016: a systematic analysis for the Global Burden of Disease Study 2016. 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