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<article article-type="research-article" dtd-version="1.3" xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink" xmlns:xsi="http://www.w3.org/2001/XMLSchema-instance" xml:lang="ru"><front><journal-meta><journal-id journal-id-type="publisher-id">cardiovascular</journal-id><journal-title-group><journal-title xml:lang="ru">Кардиоваскулярная терапия и профилактика</journal-title><trans-title-group xml:lang="en"><trans-title>Cardiovascular Therapy and Prevention</trans-title></trans-title-group></journal-title-group><issn pub-type="ppub">1728-8800</issn><issn pub-type="epub">2619-0125</issn><publisher><publisher-name>«SILICEA-POLIGRAF» LLC</publisher-name></publisher></journal-meta><article-meta><article-id pub-id-type="doi">10.15829/1728-8800-2015-6-78-82</article-id><article-id custom-type="elpub" pub-id-type="custom">cardiovascular-287</article-id><article-categories><subj-group subj-group-type="heading"><subject>Research Article</subject></subj-group><subj-group subj-group-type="section-heading" xml:lang="ru"><subject>МНЕНИЕ ПО ПРОБЛЕМЕ</subject></subj-group><subj-group subj-group-type="section-heading" xml:lang="en"><subject>OPINION ON A PROBLEM</subject></subj-group></article-categories><title-group><article-title>СТАТИНЫ ПРИ ХРОНИЧЕСКОЙ БОЛЕЗНИ ПОЧЕК. СУЩЕСТВУЕТ ЛИ ПРЕПАРАТ ВЫБОРА</article-title><trans-title-group xml:lang="en"><trans-title>STATINS IN CHRONIC KIDNEY DISEASE. IS THERE A DRUG OF CHOICE?</trans-title></trans-title-group></title-group><contrib-group><contrib contrib-type="author" corresp="yes"><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Драпкина</surname><given-names>О. М.</given-names></name><name name-style="western" xml:lang="en"><surname>Drapkina</surname><given-names>O. M.</given-names></name></name-alternatives><bio xml:lang="ru"><p>д.м.н., профессор, заместитель директора по научной и лечебной работе</p></bio><xref ref-type="aff" rid="aff-1"/></contrib><contrib contrib-type="author" corresp="yes"><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Корнеева</surname><given-names>О. Н.</given-names></name><name name-style="western" xml:lang="en"><surname>Korneeva</surname><given-names>O. N.</given-names></name></name-alternatives><bio xml:lang="ru"><p>к.м.н., главный врач</p><p>Тел.: +7 (925) 356-71-74 </p></bio><email xlink:type="simple">doctorok@land.ru</email><xref ref-type="aff" rid="aff-2"/></contrib></contrib-group><aff-alternatives id="aff-1"><aff xml:lang="ru"><institution>ФГБУ “Государственный научно-исследовательский центр профилактической медицины” Минздрава России, Москва</institution></aff><aff xml:lang="en"><institution>National Research Center for Preventive Medicine of the Ministry of Health, Moscow</institution></aff></aff-alternatives><aff-alternatives id="aff-2"><aff xml:lang="ru"><institution>Лечебно-диагностический центр “Арт-Мед кардио”, Москва</institution></aff><aff xml:lang="en"><institution>Diagnostic and Treatment Center “Art -Med”, Moscow</institution></aff></aff-alternatives><pub-date pub-type="collection"><year>2015</year></pub-date><pub-date pub-type="epub"><day>20</day><month>12</month><year>2015</year></pub-date><volume>14</volume><issue>6</issue><fpage>78</fpage><lpage>82</lpage><permissions><copyright-statement>Copyright &amp;#x00A9; Драпкина О.М., Корнеева О.Н., 2015</copyright-statement><copyright-year>2015</copyright-year><copyright-holder xml:lang="ru">Драпкина О.М., Корнеева О.Н.</copyright-holder><copyright-holder xml:lang="en">Drapkina O.M., Korneeva O.N.</copyright-holder><license xml:lang="ru" license-type="creative-commons-attribution" xlink:href="https://creativecommons.org/licenses/by/4.0/" xlink:type="simple"><license-p>Данная работа распространяется под лицензией Creative Commons Attribution 4.0.</license-p></license><license xml:lang="en" license-type="creative-commons-attribution" xlink:href="https://creativecommons.org/licenses/by/4.0/" xlink:type="simple"><license-p>This work is licensed under a Creative Commons Attribution 4.0 License.</license-p></license></permissions><self-uri xlink:href="https://cardiovascular.elpub.ru/jour/article/view/287">https://cardiovascular.elpub.ru/jour/article/view/287</self-uri><abstract><p>Хроническая болезнь почек (ХБП) ассоциирована с повышенным сердечно-сосудистым риском, и требует тщательного контроля дислипидемии. Терапия статинами признана целесообразной для профилактики и лечения сердечно-сосудистых заболеваний у пациентов с ХБП. Рассмотрены возможности применения статинов у таких пациентов, эффективность и безопасность их применения на различных стадиях ХБП, необходимость коррекции дозы, выбор конкретного статина. Проведен сравнительный анализ, обсуждены преимущества и недостатки применения розувастатина и аторвастатина при ХБП.</p></abstract><trans-abstract xml:lang="en"><p>Chronic kidney disease (CKD) is related to increased cardiovascular risk, and requires thorough dyslipidemia control. Statin therapy is expedient for prevention and treatment of cardiovascular disorders in CKD patients. The opportunities are reviewed for the use of statins in these patients, efficacy and safety at different stages of CKD, the need for dosage correction and choice of the exact drug. The comparison performed, benefits and misconveniences discussed of rosuvastatin and atorvastatin in CKD. </p></trans-abstract><kwd-group xml:lang="ru"><kwd>гиперлипидемия</kwd><kwd>хроническая болезнь почек</kwd><kwd>сердечно-сосудистый риск</kwd><kwd>аторвастатин</kwd><kwd>розувастатин</kwd><kwd>скорость клубочковой фильтрации</kwd></kwd-group><kwd-group xml:lang="en"><kwd>hyperlipidemia</kwd><kwd>chronic kidney disease</kwd><kwd>cardiovascular risk</kwd><kwd>atorvastatin</kwd><kwd>rosuvastatin</kwd><kwd>glomerular filtration rate</kwd></kwd-group></article-meta></front><back><ref-list><title>References</title><ref id="cit1"><label>1</label><citation-alternatives><mixed-citation xml:lang="ru">Gansevoort RT, Correa-Rotter R, Hemmelgarn BR, et al. Chronic kidney disease and cardiovascular risk: epidemiology, mechanisms, and prevention. Lancet 2013; 382(9889): 339-52.</mixed-citation><mixed-citation xml:lang="en">Gansevoort RT, Correa-Rotter R, Hemmelgarn BR, et al. 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