<?xml version="1.0" encoding="UTF-8"?>
<!DOCTYPE article PUBLIC "-//NLM//DTD JATS (Z39.96) Journal Publishing DTD v1.3 20210610//EN" "JATS-journalpublishing1-3.dtd">
<article article-type="research-article" dtd-version="1.3" xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink" xmlns:xsi="http://www.w3.org/2001/XMLSchema-instance" xml:lang="ru"><front><journal-meta><journal-id journal-id-type="publisher-id">cardiovascular</journal-id><journal-title-group><journal-title xml:lang="ru">Кардиоваскулярная терапия и профилактика</journal-title><trans-title-group xml:lang="en"><trans-title>Cardiovascular Therapy and Prevention</trans-title></trans-title-group></journal-title-group><issn pub-type="ppub">1728-8800</issn><issn pub-type="epub">2619-0125</issn><publisher><publisher-name>«SILICEA-POLIGRAF» LLC</publisher-name></publisher></journal-meta><article-meta><article-id pub-id-type="doi">10.15829/1728-8800-2021-2998</article-id><article-id custom-type="elpub" pub-id-type="custom">cardiovascular-2998</article-id><article-categories><subj-group subj-group-type="heading"><subject>Research Article</subject></subj-group><subj-group subj-group-type="section-heading" xml:lang="ru"><subject>ОБЗОРЫ ЛИТЕРАТУРЫ</subject></subj-group><subj-group subj-group-type="section-heading" xml:lang="en"><subject>REVIEW ARTICLES</subject></subj-group></article-categories><title-group><article-title>Преабилитация как важный этап перед кардиохирургическими вмешательствами</article-title><trans-title-group xml:lang="en"><trans-title>Prehabilitation as an important stage before cardiac surgery</trans-title></trans-title-group></title-group><contrib-group><contrib contrib-type="author" corresp="yes"><contrib-id contrib-id-type="orcid">https://orcid.org/0000-0003-2250-5942</contrib-id><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Бубнова</surname><given-names>М. Г.</given-names></name><name name-style="western" xml:lang="en"><surname>Bubnova</surname><given-names>M. G.</given-names></name></name-alternatives><bio xml:lang="ru"><p>Марина Геннадьевна Бубнова — доктор медицинских наук, профессор, руководитель отдела реабилитации и вторичной профилактики сердечно-сосудистых заболеваний.</p><p>Москва, Тел.: +7 (903) 752-21-86</p></bio><bio xml:lang="en"><p>MD, PhD, Professor; head of department of rehabilitation and secondary prevention for Cardiovascular Disease</p><p>Moscow</p></bio><email xlink:type="simple">mbubnova@gnicpm.ru</email><xref ref-type="aff" rid="aff-1"/></contrib><contrib contrib-type="author" corresp="yes"><contrib-id contrib-id-type="orcid">https://orcid.org/0000-0003-0484-9805</contrib-id><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Аронов</surname><given-names>Д. М.</given-names></name><name name-style="western" xml:lang="en"><surname>Aronov</surname><given-names>D. M.</given-names></name></name-alternatives><bio xml:lang="ru"><p>Марина Геннадьевна Бубнова — доктор медицинских наук, профессор, руководитель отдела реабилитации и вторичной профилактики сердечно-сосудистых заболеваний.</p><p>Москва, Тел.: +7 (903) 752-21-86</p></bio><bio xml:lang="en"><p>MD, PhD, Professor; chief scientific researcher</p><p>Moscow</p></bio><email xlink:type="simple">aronovdm@mail.ru</email><xref ref-type="aff" rid="aff-1"/></contrib><contrib contrib-type="author" corresp="yes"><contrib-id contrib-id-type="orcid">https://orcid.org/0000-0003-0875-4205</contrib-id><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Сприкут</surname><given-names>А. А.</given-names></name><name name-style="western" xml:lang="en"><surname>Sprikut</surname><given-names>A. A.</given-names></name></name-alternatives><bio xml:lang="ru"><p>Анна Александровна Сприкут — кандидат медицинских наук, зав. отделением кардиореабилитации.</p><p>Челябинск</p></bio><bio xml:lang="en"><p>сandidate of Medicine, Head of Cardiac Rehabilitation Department.</p><p>Chelyabinsk</p></bio><email xlink:type="simple">mbubnova@gnicpm.ru</email><xref ref-type="aff" rid="aff-2"/></contrib><contrib contrib-type="author" corresp="yes"><contrib-id contrib-id-type="orcid">https://orcid.org/0000-0003-0342-539X</contrib-id><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Станкевич</surname><given-names>Д. И.</given-names></name><name name-style="western" xml:lang="en"><surname>Stankevich</surname><given-names>D. I.</given-names></name></name-alternatives><bio xml:lang="ru"><p>Дарья Игоревна Станкевич — кардиолог отделения кардиореабилитации.</p><p>Челябинск</p></bio><bio xml:lang="en"><p>cardiologist of Cardiac Rehabilitation Department</p><p>Chelyabinsk</p></bio><email xlink:type="simple">mbubnova@gnicpm.ru</email><xref ref-type="aff" rid="aff-2"/></contrib><contrib contrib-type="author" corresp="yes"><contrib-id contrib-id-type="orcid">https://orcid.org/0000-0002-9155-9189</contrib-id><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Поддубская</surname><given-names>Е. А.</given-names></name><name name-style="western" xml:lang="en"><surname>Poddubskaya</surname><given-names>E. A.</given-names></name></name-alternatives><bio xml:lang="ru"><p>Елена Александровна Поддубская — кандидат медицинских наук, ученый секретарь.</p><p>Москва</p></bio><bio xml:lang="en"><p>сandidate of Medicine, scientific secretary</p><p>Moscow</p></bio><email xlink:type="simple">EPoddubskaya@gnicpm.ru</email><xref ref-type="aff" rid="aff-1"/></contrib><contrib contrib-type="author" corresp="yes"><contrib-id contrib-id-type="orcid">https://orcid.org/0000-0002-8508-5327</contrib-id><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Персиянова-Дуброва</surname><given-names>А. Л.</given-names></name><name name-style="western" xml:lang="en"><surname>Persiyanova-Dubrova</surname><given-names>A. L.</given-names></name></name-alternatives><bio xml:lang="ru"><p>Анна Леонидовна Персиянова-Дуброва — кандидат медицинских наук, старший научный сотрудник отдела реабилитации и вторичной профилактики сердечно-сосудистых заболеваний.</p><p>Москва</p></bio><bio xml:lang="en"><p>сandidate of Medicine, senior scientific researcher of department of rehabilitation and secondary prevention for Cardiovascular Disease.</p><p>Moscow</p></bio><email xlink:type="simple">apersiyanova@gnicpm.ru</email><xref ref-type="aff" rid="aff-1"/></contrib></contrib-group><aff-alternatives id="aff-1"><aff xml:lang="ru"><institution>ФГБУ Национальный медицинский исследовательский центр терапии и профилактической медицины Министерства здравоохранения Российской Федерации</institution></aff><aff xml:lang="en"><institution>National Medical Research Center for Therapy and Preventive Medicine</institution></aff></aff-alternatives><aff-alternatives id="aff-2"><aff xml:lang="ru"><institution>МБУЗ Городская клиническая больница № 2</institution></aff><aff xml:lang="en"><institution>City Clinical Hospital № 2</institution></aff></aff-alternatives><pub-date pub-type="collection"><year>2021</year></pub-date><pub-date pub-type="epub"><day>15</day><month>10</month><year>2021</year></pub-date><volume>20</volume><issue>6</issue><fpage>2998</fpage><lpage>2998</lpage><permissions><copyright-statement>Copyright &amp;#x00A9; Бубнова М.Г., Аронов Д.М., Сприкут А.А., Станкевич Д.И., Поддубская Е.А., Персиянова-Дуброва А.Л., 2021</copyright-statement><copyright-year>2021</copyright-year><copyright-holder xml:lang="ru">Бубнова М.Г., Аронов Д.М., Сприкут А.А., Станкевич Д.И., Поддубская Е.А., Персиянова-Дуброва А.Л.</copyright-holder><copyright-holder xml:lang="en">Bubnova M.G., Aronov D.M., Sprikut A.A., Stankevich D.I., Poddubskaya E.A., Persiyanova-Dubrova A.L.</copyright-holder><license xml:lang="ru" license-type="creative-commons-attribution" xlink:href="https://creativecommons.org/licenses/by/4.0/" xlink:type="simple"><license-p>Данная работа распространяется под лицензией Creative Commons Attribution 4.0.</license-p></license><license xml:lang="en" license-type="creative-commons-attribution" xlink:href="https://creativecommons.org/licenses/by/4.0/" xlink:type="simple"><license-p>This work is licensed under a Creative Commons Attribution 4.0 License.</license-p></license></permissions><self-uri xlink:href="https://cardiovascular.elpub.ru/jour/article/view/2998">https://cardiovascular.elpub.ru/jour/article/view/2998</self-uri><abstract><p>В обзоре обсуждаются вопросы подготовки пациентов к операциям на сердце и других органов. Рассматривается важность введения нового этапа медицинской и кардиологической реабилитации — преабилитации. Представляются результаты рандомизированных клинических исследований, систематических обзоров и метаанализов, посвященных оценке эффективности респираторных техник и физических тренировок на этапе преабилитации. Особое внимание уделяется вовлечению в программы преабилитации пациентов перед планируемой операцией коронарного шунтирования. Обсуждаются методологические проблемы, возникающие при разработке преабилитационных программ.</p></abstract><trans-abstract xml:lang="en"><p>The review discusses the preparation of patients for surgery on the heart and other organs. We considered the importance of introducing a new stage of medical and cardiology rehabilitation — prehabilitation. The results of randomized clinical trials, systematic reviews and metaanalyzes evaluating the effectiveness of respiratory techniques and physical training during the prehabilitation are presented. Particular attention is paid to the involvement of patients in prehabilitation programs before the elective coronary artery bypass grafting. Methodological problems arising in the development of prehabilitation programs are discussed.</p></trans-abstract><kwd-group xml:lang="ru"><kwd>преабилитация</kwd><kwd>кардиореабилитация</kwd><kwd>коронарное шунтирование</kwd><kwd>физические тренировки</kwd><kwd>предоперационная подготовка</kwd></kwd-group><kwd-group xml:lang="en"><kwd>prehabilitation</kwd><kwd>cardiac rehabilitation</kwd><kwd>coronary artery bypass grafting</kwd><kwd>physical training</kwd><kwd>preoperative preparation</kwd></kwd-group></article-meta></front><back><ref-list><title>References</title><ref id="cit1"><label>1</label><citation-alternatives><mixed-citation xml:lang="ru">Бокерия Л. А. Сердечно-сосудистая хирургия-2019. М.: НЦССХ им. А. Н. Бакулева, 2020. 294 с. ISBN: 978-5-7982-0367-3.</mixed-citation><mixed-citation xml:lang="en">Bokeriya LA. Serdechno-sosudistaya khirurgiya-2019. M.: Bakoulev SCCS RAMS, 2020. 294 p. (In Russ.) ISBN: 978-5-7982-0367-3.</mixed-citation></citation-alternatives></ref><ref id="cit2"><label>2</label><citation-alternatives><mixed-citation xml:lang="ru">Neumann F-J, Sousa-Uva M, Ahlsson A, et al. 2018 ESC/EACTS Guidelines on myocardial revascularization. The Task Force on myocardial revascularization of the European Society of Cardiology (ESC) and European Association for Cardio-Thoracic Surgery (EACTS). Eur Heart J. 2019;40:87-165. doi:10.1093/eurheartj/ehy394.</mixed-citation><mixed-citation xml:lang="en">Neumann F-J, Sousa-Uva M, Ahlsson A, et al. 2018 ESC/EACTS Guidelines on myocardial revascularization. The Task Force on myocardial revascularization of the European Society of Cardiology (ESC) and European Association for Cardio-Thoracic Surgery (EACTS). Eur Heart J. 2019;40:87-165. doi:10.1093/eurheartj/ehy394.</mixed-citation></citation-alternatives></ref><ref id="cit3"><label>3</label><citation-alternatives><mixed-citation xml:lang="ru">Аронов Д. М., Бубнова М. Г., Бойцов С. А. и др. Организационные вопросы кардиореабилитационной службы в России. Результаты Пилотного Проекта “Развитие системы реабилитации больных с сердечно-сосудистыми заболеваниями в лечебных учреждениях субъектов Российской Федерации”. Кардиоваскулярная терапия и профилактика. 2016;15(6):4-12. doi:10.15829/1728-8800-2016-6-4-12.</mixed-citation><mixed-citation xml:lang="en">Aronov DM, Bubnova MG, Boytsov SA, et al. Organizational issues of cardiorehabilitation service in Russia. The results of Pilot project “Development of rehabilitation system of cardiovascular patients in medical institutions of Russian Federation entities”. Cardiovascular Therapy and Prevention. 2016;15(6):4-12. (In Russ.) doi:10.15829/1728-8800-2016-6-4-12.</mixed-citation></citation-alternatives></ref><ref id="cit4"><label>4</label><citation-alternatives><mixed-citation xml:lang="ru">Аронов Д. М., Бубнова М. Г. Проблемы внедрения новой системы кардиореабилитации в России. Российский кардиологический журнал. 2013;(4):14-22. doi:10.15829/1560-4071-2013-4-14-22.</mixed-citation><mixed-citation xml:lang="en">Aronov DM, Bubnova MG. Challenges of the implementation of a new cardiac rehabilitation system in Russia. Russian Journal of Cardiology. 2013;(4):14-22. (In Russ.) doi:10.15829/1560-4071-2013-4-14-22.</mixed-citation></citation-alternatives></ref><ref id="cit5"><label>5</label><citation-alternatives><mixed-citation xml:lang="ru">Ditmyer MM, Topp R, Pifer M. Prehabilitation in preparation for orthopaedic surgery. Orthop Nurs. 2002;21:43-51. doi:10.1097/00006416-200209000-00008.</mixed-citation><mixed-citation xml:lang="en">Ditmyer MM, Topp R, Pifer M. Prehabilitation in preparation for orthopaedic surgery. Orthop Nurs. 2002;21:43-51. doi:10.1097/00006416-200209000-00008.</mixed-citation></citation-alternatives></ref><ref id="cit6"><label>6</label><citation-alternatives><mixed-citation xml:lang="ru">Бокерия Л. А., Аронов Д. М., Барбараш О. Л. и др. Российские клинические рекомендации. Коронарное шунтирование больных ишемической болезнью сердца: реабилитация и вторичная профилактика. CardioCoMaTUka. 2016;7(3-4):5-71.</mixed-citation><mixed-citation xml:lang="en">Bokeriya LA, Aronov DM, Barbarash OL, et al. Russian clinical guidelines. Coronary artery bypass grafting in patients with ischemic heart disease: rehabilitation and secondary prevention Cardiosomatics. 2016;7(3-4):5-71. (In Russ.)</mixed-citation></citation-alternatives></ref><ref id="cit7"><label>7</label><citation-alternatives><mixed-citation xml:lang="ru">Prehabilitation, rehabilitation, and revocation in the Army. Br Med J. 1946;1:192-7. PMID:20989832.</mixed-citation><mixed-citation xml:lang="en">Prehabilitation, rehabilitation, and revocation in the Army. Br Med J. 1946;1:192-7. PMID:20989832.</mixed-citation></citation-alternatives></ref><ref id="cit8"><label>8</label><citation-alternatives><mixed-citation xml:lang="ru">Banugo P, Amoako D. Prehabilitation. BJA Educ. 2017;17:401-5. doi:10.1093/bjaed/mkx032.</mixed-citation><mixed-citation xml:lang="en">Banugo P, Amoako D. Prehabilitation. BJA Educ. 2017;17:401-5. doi:10.1093/bjaed/mkx032.</mixed-citation></citation-alternatives></ref><ref id="cit9"><label>9</label><citation-alternatives><mixed-citation xml:lang="ru">Valkenet K, van de Port IG, Dronkers JJ, et al. The effects of preoperative exercise therapy on postoperative outcome: a systematic review. Clin Rehabil. 2011;25(2):99-111. doi:10.1177/026921551038083.</mixed-citation><mixed-citation xml:lang="en">Valkenet K, van de Port IG, Dronkers JJ, et al. The effects of preoperative exercise therapy on postoperative outcome: a systematic review. Clin Rehabil. 2011;25(2):99-111. doi:10.1177/026921551038083.</mixed-citation></citation-alternatives></ref><ref id="cit10"><label>10</label><citation-alternatives><mixed-citation xml:lang="ru">Santa Mina D, Clarke H, Ritvo P. Effect of total-body preha-bilitation on postoperative outcomes: a systematic review and meta-analysis. Physiotherapy. 2014;100(3):196-207. doi:10.1016/j.physio.2013.08.008.</mixed-citation><mixed-citation xml:lang="en">Santa Mina D, Clarke H, Ritvo P. Effect of total-body preha-bilitation on postoperative outcomes: a systematic review and meta-analysis. Physiotherapy. 2014;100(3):196-207. doi:10.1016/j.physio.2013.08.008.</mixed-citation></citation-alternatives></ref><ref id="cit11"><label>11</label><citation-alternatives><mixed-citation xml:lang="ru">Garcia R, Yanez Brageb M, Moolhuyzenc E, et al. Functional and postoperative outcomes after preoperative exercise training in patients with lung cancer: a systematic review and metaanalysis. Interact Cardiovasc. Thorac Surg. 2016;23:486-97. doi:10.1093/icvts/ivw152.</mixed-citation><mixed-citation xml:lang="en">Garcia R, Yanez Brageb M, Moolhuyzenc E, et al. Functional and postoperative outcomes after preoperative exercise training in patients with lung cancer: a systematic review and metaanalysis. Interact Cardiovasc. Thorac Surg. 2016;23:486-97. doi:10.1093/icvts/ivw152.</mixed-citation></citation-alternatives></ref><ref id="cit12"><label>12</label><citation-alternatives><mixed-citation xml:lang="ru">Coats V, Maltais F, Simard S, et al. Feasibility and effectiveness of a home-based exercise training program before lung resection surgery. Can Respir J. 2013;20(2):e10-6. doi:10.1155/2013/291059.</mixed-citation><mixed-citation xml:lang="en">Coats V, Maltais F, Simard S, et al. Feasibility and effectiveness of a home-based exercise training program before lung resection surgery. Can Respir J. 2013;20(2):e10-6. doi:10.1155/2013/291059.</mixed-citation></citation-alternatives></ref><ref id="cit13"><label>13</label><citation-alternatives><mixed-citation xml:lang="ru">Arthur HM, Daniels C, McKelvie R, et al. Effect of a preoperative intervention on preoperative and postoperative outcomes in low-risk patients awaiting elective coronary artery bypass graft surgery. A randomized, controlled trial. Ann Intern Med. 2000;133(4):253-62. doi:10.7326/0003-4819-133-4-200008150-00007.</mixed-citation><mixed-citation xml:lang="en">Arthur HM, Daniels C, McKelvie R, et al. Effect of a preoperative intervention on preoperative and postoperative outcomes in low-risk patients awaiting elective coronary artery bypass graft surgery. A randomized, controlled trial. Ann Intern Med. 2000;133(4):253-62. doi:10.7326/0003-4819-133-4-200008150-00007.</mixed-citation></citation-alternatives></ref><ref id="cit14"><label>14</label><citation-alternatives><mixed-citation xml:lang="ru">Blackwell JEM, Doleman B, Boereboom CL, et al. High-intensity interval training produces a significant improvement in fitness in less than 31 days before surgery for urological cancer: a randomized control trial. Prostate Cancer Prostatic Dis. 2020;23(4):696-704. doi:10.1038/s41391-020-0219-1.</mixed-citation><mixed-citation xml:lang="en">Blackwell JEM, Doleman B, Boereboom CL, et al. High-intensity interval training produces a significant improvement in fitness in less than 31 days before surgery for urological cancer: a randomized control trial. Prostate Cancer Prostatic Dis. 2020;23(4):696-704. doi:10.1038/s41391-020-0219-1.</mixed-citation></citation-alternatives></ref><ref id="cit15"><label>15</label><citation-alternatives><mixed-citation xml:lang="ru">Smith JL, Verrill TA, Boura JA, et al. Effect of cardiorespiratory fitness on short-term morbidity and mortality after coronary artery bypass grafting. Am J Cardiol. 2013;112(8):1104-9. doi:10.1016/j.amjcard.2013.05.057.</mixed-citation><mixed-citation xml:lang="en">Smith JL, Verrill TA, Boura JA, et al. Effect of cardiorespiratory fitness on short-term morbidity and mortality after coronary artery bypass grafting. Am J Cardiol. 2013;112(8):1104-9. doi:10.1016/j.amjcard.2013.05.057.</mixed-citation></citation-alternatives></ref><ref id="cit16"><label>16</label><citation-alternatives><mixed-citation xml:lang="ru">Kehler DS, Stammers AN, Horne D, et al. Impact of preoperative physical activity and depressive symptoms on post-cardiac surgical outcomes. PLoS One. 2019;14(2):e0213324. doi:10.1371/journal.pone.0213324.</mixed-citation><mixed-citation xml:lang="en">Kehler DS, Stammers AN, Horne D, et al. Impact of preoperative physical activity and depressive symptoms on post-cardiac surgical outcomes. PLoS One. 2019;14(2):e0213324. doi:10.1371/journal.pone.0213324.</mixed-citation></citation-alternatives></ref><ref id="cit17"><label>17</label><citation-alternatives><mixed-citation xml:lang="ru">Cook JW, Pierson LM, Herbert WG, et al. The influence of patient strength, aerobic capacity and body composition upon outcomes after coronary artery bypass grafting. Thorac Cardiovasc Surg. 2001;49(2):89-93. doi:10.1055/s-2001-11703.</mixed-citation><mixed-citation xml:lang="en">Cook JW, Pierson LM, Herbert WG, et al. The influence of patient strength, aerobic capacity and body composition upon outcomes after coronary artery bypass grafting. Thorac Cardiovasc Surg. 2001;49(2):89-93. doi:10.1055/s-2001-11703.</mixed-citation></citation-alternatives></ref><ref id="cit18"><label>18</label><citation-alternatives><mixed-citation xml:lang="ru">Fu L, Zhang Y, Shao B, et al. Perioperative poor grip strength recovery is associated with 30-day complication rate after cardiac surgery discharge in middle-aged and older adults — a prospective observational study. BMC Cardiovasc Disord. 2019;19(1):266. doi:10.1186/s12872-019-1241-x.</mixed-citation><mixed-citation xml:lang="en">Fu L, Zhang Y, Shao B, et al. Perioperative poor grip strength recovery is associated with 30-day complication rate after cardiac surgery discharge in middle-aged and older adults — a prospective observational study. BMC Cardiovasc Disord. 2019;19(1):266. doi:10.1186/s12872-019-1241-x.</mixed-citation></citation-alternatives></ref><ref id="cit19"><label>19</label><citation-alternatives><mixed-citation xml:lang="ru">Yau JM, Alexander JH, Hafley G, et al. PREVENT IV Investigators. Impact of perioperative myocardial infarction on angiographic and clinical outcomes following coronary artery bypass grafting (from PRoject of Ex-vivo Vein graft ENgineering via Transfection [PREVENT] IV). Am J Cardiol. 2008;102(5):546-51. doi:10.1016/j.amjcard.2008.04.069.</mixed-citation><mixed-citation xml:lang="en">Yau JM, Alexander JH, Hafley G, et al. PREVENT IV Investigators. Impact of perioperative myocardial infarction on angiographic and clinical outcomes following coronary artery bypass grafting (from PRoject of Ex-vivo Vein graft ENgineering via Transfection [PREVENT] IV). Am J Cardiol. 2008;102(5):546-51. doi:10.1016/j.amjcard.2008.04.069.</mixed-citation></citation-alternatives></ref><ref id="cit20"><label>20</label><citation-alternatives><mixed-citation xml:lang="ru">Mebazaa A, Pitsis AA, Rudiger A, et al. Clinical review: practical recommendations on the management of perioperative heart failure in cardiac surgery. Critical care. 2010;14(2):201. doi:10.1186/cc8153.</mixed-citation><mixed-citation xml:lang="en">Mebazaa A, Pitsis AA, Rudiger A, et al. Clinical review: practical recommendations on the management of perioperative heart failure in cardiac surgery. Critical care. 2010;14(2):201. doi:10.1186/cc8153.</mixed-citation></citation-alternatives></ref><ref id="cit21"><label>21</label><citation-alternatives><mixed-citation xml:lang="ru">Tritapepe L, De Santis V, Vitale D, et al. Levosimendan pretreatment improves outcomes in patients undergoing coronary artery bypass graft surgery. Br J Anaesth. 2009;102(2):198-204. doi:10.1093/bja/aen367.</mixed-citation><mixed-citation xml:lang="en">Tritapepe L, De Santis V, Vitale D, et al. Levosimendan pretreatment improves outcomes in patients undergoing coronary artery bypass graft surgery. Br J Anaesth. 2009;102(2):198-204. doi:10.1093/bja/aen367.</mixed-citation></citation-alternatives></ref><ref id="cit22"><label>22</label><citation-alternatives><mixed-citation xml:lang="ru">Murry CE, Jennings RB, Reimer KA. Preconditioning with ischemia: a delay of lethal cell injury in ischemic myocardium. Circulation. 1986;74(5):1124-36. doi:10.1161/01.cir.74.5.1124.</mixed-citation><mixed-citation xml:lang="en">Murry CE, Jennings RB, Reimer KA. Preconditioning with ischemia: a delay of lethal cell injury in ischemic myocardium. Circulation. 1986;74(5):1124-36. doi:10.1161/01.cir.74.5.1124.</mixed-citation></citation-alternatives></ref><ref id="cit23"><label>23</label><citation-alternatives><mixed-citation xml:lang="ru">Лупанов В.П., Максименко А.В. Протективная ишемия в кардиологии. Формы кондиционирования миокарда. Кардиоваскулярная терапия и профилактика. 2011;10(1):96-103.</mixed-citation><mixed-citation xml:lang="en">Lupanov VP, Maksimenko AV. Protective ischemia in cardiology. Myocardial conditioning forms. Cardiovascular Therapy and Prevention. 2011;10(1):96-103. (In Russ.)</mixed-citation></citation-alternatives></ref><ref id="cit24"><label>24</label><citation-alternatives><mixed-citation xml:lang="ru">Аргунова Ю. А., Короткевич А. А., Помешкина С. А. и др. Эффективность физических тренировок как метода кардиопротекции у пациентов перед коронарным шунтированием. Российский кардиологический журнал. 2018;(6):159-165. doi:10.15829/1560-4071-2018-6-159-165.</mixed-citation><mixed-citation xml:lang="en">Argunova YuA, Korotkevich АА, Pomeshkina SA, et al. Efficacy of physical trainings as cardioprotection method for coronary bypass surgery. Russ J Cardiol. 2018;(6):159-165. (In Russ.) doi:10.15829/1560-4071-2018-6-159-165.</mixed-citation></citation-alternatives></ref><ref id="cit25"><label>25</label><citation-alternatives><mixed-citation xml:lang="ru">Аргунова Ю. А., Помешкина С. А., Иноземцева А. А. и др. Клиническая эффективность преабилитации у пациентов, подвергшихся коронарному шунтированию. Комплексные проблемы сердечно-сосудистых заболеваний. 2018;7(4S):15-23. doi:10.17802/2306-1278-2018-7-4S-15-23.</mixed-citation><mixed-citation xml:lang="en">Argunova YA, Pomeshkina SA, Inozemtseva AA, et al. Clinical efficiency of prehabilitation program in patients undergoing coronary artery bypass grafting. Complex Issues of Cardiovascular Diseases. 2018;7(4S):15-23. (In Russ.) doi:10.17802/2306-1278-2018-7-4S-15-23.</mixed-citation></citation-alternatives></ref><ref id="cit26"><label>26</label><citation-alternatives><mixed-citation xml:lang="ru">Sawatzky JA, Kehler DS, Ready AE, et al. Prehabilitation program for elective coronary artery bypass graft surgery patients: a pilot randomized controlled study. Clin Rehabil. 2014;28(7):648657. doi:10.1177/0269215513516475.</mixed-citation><mixed-citation xml:lang="en">Sawatzky JA, Kehler DS, Ready AE, et al. Prehabilitation program for elective coronary artery bypass graft surgery patients: a pilot randomized controlled study. Clin Rehabil. 2014;28(7):648657. doi:10.1177/0269215513516475.</mixed-citation></citation-alternatives></ref><ref id="cit27"><label>27</label><citation-alternatives><mixed-citation xml:lang="ru">Wynne R, Botti M. Postoperative pulmonary dysfunction in adults after cardiac surgery with cardiopulmonary bypass: clinical significance and implications for practice. Am J Crit Care. 2004;13(5):384-93.</mixed-citation><mixed-citation xml:lang="en">Wynne R, Botti M. Postoperative pulmonary dysfunction in adults after cardiac surgery with cardiopulmonary bypass: clinical significance and implications for practice. Am J Crit Care. 2004;13(5):384-93.</mixed-citation></citation-alternatives></ref><ref id="cit28"><label>28</label><citation-alternatives><mixed-citation xml:lang="ru">Медресова А. Т., Лукашкин М. А., Голухова Е. З. и др. Послеоперационные легочные осложнения у кардиохирургических пациентов. Креативная кардиология. 2010;1:5-16.</mixed-citation><mixed-citation xml:lang="en">Medresova AT, Lukashkin MA, Goluhova EZ, et al. Postoperative pulmonary complications in patients undergoing cardiac surgery. Kreativnaja kardiologija. 2010;1:5-16. (In Russ)</mixed-citation></citation-alternatives></ref><ref id="cit29"><label>29</label><citation-alternatives><mixed-citation xml:lang="ru">Власова Э. Е., Комлев А. Е., Васильев В. П. и др. Ускоренная госпитальная реабилитация после коронарного шунтирования с искусственным кровообращением. Кардиологический вестник. 2009;1:33-9.</mixed-citation><mixed-citation xml:lang="en">Vlasova JeE, Komlev AE, Vasil'ev VP, et al. Express-hospital rehabilitation after coronary artery bypass grafting with cardiopulmonary bypass. Kardiologicheskij vestnik. 2009;1:33-9. (In Russ).</mixed-citation></citation-alternatives></ref><ref id="cit30"><label>30</label><citation-alternatives><mixed-citation xml:lang="ru">Hulzebos EH, van Meeteren NL, van den Buijs BJ, et al. Feasibility of preoperative inspiratory muscle training in patients undergoing coronary artery bypass surgery with a high risk of postoperative pulmonary complications: a randomized controlled pilot study. Clin Rehabil. 2006;20(11):949-59. doi:10.1177/0269215506070691.</mixed-citation><mixed-citation xml:lang="en">Hulzebos EH, van Meeteren NL, van den Buijs BJ, et al. Feasibility of preoperative inspiratory muscle training in patients undergoing coronary artery bypass surgery with a high risk of postoperative pulmonary complications: a randomized controlled pilot study. Clin Rehabil. 2006;20(11):949-59. doi:10.1177/0269215506070691.</mixed-citation></citation-alternatives></ref><ref id="cit31"><label>31</label><citation-alternatives><mixed-citation xml:lang="ru">Hulzebos EH, Helders PJ, Favie NJ, et al. Preoperative intensive inspiratory muscle training to prevent postoperative pulmonary complications in high-risk patients undergoing CABG surgery: a randomized clinical trial. JAMA. 2006;18;296(15):1851-7. doi:10.1001/jama.296.15.1851.</mixed-citation><mixed-citation xml:lang="en">Hulzebos EH, Helders PJ, Favie NJ, et al. Preoperative intensive inspiratory muscle training to prevent postoperative pulmonary complications in high-risk patients undergoing CABG surgery: a randomized clinical trial. JAMA. 2006;18;296(15):1851-7. doi:10.1001/jama.296.15.1851.</mixed-citation></citation-alternatives></ref><ref id="cit32"><label>32</label><citation-alternatives><mixed-citation xml:lang="ru">Ferreira PE, Rodrigues AJ, Evora PR. Effects of an inspiratory muscle rehabilitation program in the postoperative period of cardiac surgery. Arq Bras Cardiol. 2009;92(4):275-82. English, Portuguese, Spanish. doi:10.1590/s0066-782x2009000400005.</mixed-citation><mixed-citation xml:lang="en">Ferreira PE, Rodrigues AJ, Evora PR. Effects of an inspiratory muscle rehabilitation program in the postoperative period of cardiac surgery. Arq Bras Cardiol. 2009;92(4):275-82. English, Portuguese, Spanish. doi:10.1590/s0066-782x2009000400005.</mixed-citation></citation-alternatives></ref><ref id="cit33"><label>33</label><citation-alternatives><mixed-citation xml:lang="ru">Savci S, Degirmenci B, Saglam M, et al. Short-term effects of inspiratory muscle training in coronary artery bypass graft surgery: a randomized controlled trial. Scand Cardiovasc J. 2011;45(5):286-93. doi:10.3109/14017431.2011.595820.</mixed-citation><mixed-citation xml:lang="en">Savci S, Degirmenci B, Saglam M, et al. Short-term effects of inspiratory muscle training in coronary artery bypass graft surgery: a randomized controlled trial. Scand Cardiovasc J. 2011;45(5):286-93. doi:10.3109/14017431.2011.595820.</mixed-citation></citation-alternatives></ref><ref id="cit34"><label>34</label><citation-alternatives><mixed-citation xml:lang="ru">Sobrinho MT, Guirado GN, Silva MA. Preoperative therapy restores ventilatory parameters and reduces length of stay in patients undergoing myocardial revascularization. Rev Bras Cir Cardiovasc. 2014;29(2):221-8. doi:10.5935/1678-9741.20140021.</mixed-citation><mixed-citation xml:lang="en">Sobrinho MT, Guirado GN, Silva MA. Preoperative therapy restores ventilatory parameters and reduces length of stay in patients undergoing myocardial revascularization. Rev Bras Cir Cardiovasc. 2014;29(2):221-8. doi:10.5935/1678-9741.20140021.</mixed-citation></citation-alternatives></ref><ref id="cit35"><label>35</label><citation-alternatives><mixed-citation xml:lang="ru">Valkenet K, Trappenburg JCA, Hulzebos EH, et al. Effects of a pre-operative home-based inspiratory muscle training programme on perceived health-related quality of life in patients undergoing coronary artery bypass graft surgery. Physiotherapy. 2017;103(3):276-82. doi:10.1016/j.physio.2016.02.007.</mixed-citation><mixed-citation xml:lang="en">Valkenet K, Trappenburg JCA, Hulzebos EH, et al. Effects of a pre-operative home-based inspiratory muscle training programme on perceived health-related quality of life in patients undergoing coronary artery bypass graft surgery. Physiotherapy. 2017;103(3):276-82. doi:10.1016/j.physio.2016.02.007.</mixed-citation></citation-alternatives></ref><ref id="cit36"><label>36</label><citation-alternatives><mixed-citation xml:lang="ru">Shakouri SK, Salekzamani Y, Taghizadieh A, et al. Effect of Respiratory Rehabilitation Before Open Cardiac Surgery on Respiratory Function: A Randomized Clinical Trial. J Cardiovasc Thorac Res. 2015;7(1):13-7. doi:10.15171/jcvtr.2015.03.</mixed-citation><mixed-citation xml:lang="en">Shakouri SK, Salekzamani Y, Taghizadieh A, et al. Effect of Respiratory Rehabilitation Before Open Cardiac Surgery on Respiratory Function: A Randomized Clinical Trial. J Cardiovasc Thorac Res. 2015;7(1):13-7. doi:10.15171/jcvtr.2015.03.</mixed-citation></citation-alternatives></ref><ref id="cit37"><label>37</label><citation-alternatives><mixed-citation xml:lang="ru">Nardi P, Pellegrino A, Pisano C, et al. The effect of preoperative respiratory physiotherapy and motor exercise in patients undergoing elective cardiac surgery: short-term results. Kardio-chirurgia i Torakochirurgia Polska = Polish Journal of Cardio-thoracic Surgery. 2019;16(2):81-7. doi:10.5114/kitp.2019.86360.</mixed-citation><mixed-citation xml:lang="en">Nardi P, Pellegrino A, Pisano C, et al. The effect of preoperative respiratory physiotherapy and motor exercise in patients undergoing elective cardiac surgery: short-term results. Kardio-chirurgia i Torakochirurgia Polska = Polish Journal of Cardio-thoracic Surgery. 2019;16(2):81-7. doi:10.5114/kitp.2019.86360.</mixed-citation></citation-alternatives></ref><ref id="cit38"><label>38</label><citation-alternatives><mixed-citation xml:lang="ru">Waite I, Deshpande R, Baghai M, et al. Home-based preoperative rehabilitation (prehab) to improve physical function and reduce hospital length of stay for frail patients undergoing coronary artery bypass graft and valve surgery. J Cardiothorac Surg. 2017;12(1):91. doi:10.1186/s13019-017-0655-8.</mixed-citation><mixed-citation xml:lang="en">Waite I, Deshpande R, Baghai M, et al. Home-based preoperative rehabilitation (prehab) to improve physical function and reduce hospital length of stay for frail patients undergoing coronary artery bypass graft and valve surgery. J Cardiothorac Surg. 2017;12(1):91. doi:10.1186/s13019-017-0655-8.</mixed-citation></citation-alternatives></ref><ref id="cit39"><label>39</label><citation-alternatives><mixed-citation xml:lang="ru">Marmelo F, Rocha V, Goncalves D. The impact of prehabilitation on post-surgical complications in patients undergoing nonurgent cardiovascular surgical intervention: Systematic review and meta- analysis. Eur J Prev Cardiol. 2018;25(4):404-17. doi:10.1177/2047487317752373.</mixed-citation><mixed-citation xml:lang="en">Marmelo F, Rocha V, Goncalves D. The impact of prehabilitation on post-surgical complications in patients undergoing nonurgent cardiovascular surgical intervention: Systematic review and meta- analysis. Eur J Prev Cardiol. 2018;25(4):404-17. doi:10.1177/2047487317752373.</mixed-citation></citation-alternatives></ref><ref id="cit40"><label>40</label><citation-alternatives><mixed-citation xml:lang="ru">Herdy AH, Marcchi PL, Vila A, et al. Pre- and postoperative cardiopulmonary rehabilitation in hospitalized patients undergoing coronary artery bypass surgery: a randomized controlled trial. Am J Phys Med Rehabil. 2008;87(9):714-9. doi:10.1097/PHM.0b013e3181839152.</mixed-citation><mixed-citation xml:lang="en">Herdy AH, Marcchi PL, Vila A, et al. Pre- and postoperative cardiopulmonary rehabilitation in hospitalized patients undergoing coronary artery bypass surgery: a randomized controlled trial. Am J Phys Med Rehabil. 2008;87(9):714-9. doi:10.1097/PHM.0b013e3181839152.</mixed-citation></citation-alternatives></ref><ref id="cit41"><label>41</label><citation-alternatives><mixed-citation xml:lang="ru">Yau DKW, Underwood MJ, Joynt GM, Lee A. Effect of preparative rehabilitation on recovery after cardiac surgery: A systematic review. Ann Phys Rehabil Med. 2020;14:S1877-0657(20)30105-6. doi:10.1016/j.rehab.2020.03.014.</mixed-citation><mixed-citation xml:lang="en">Yau DKW, Underwood MJ, Joynt GM, Lee A. Effect of preparative rehabilitation on recovery after cardiac surgery: A systematic review. Ann Phys Rehabil Med. 2020;14:S1877-0657(20)30105-6. doi:10.1016/j.rehab.2020.03.014.</mixed-citation></citation-alternatives></ref><ref id="cit42"><label>42</label><citation-alternatives><mixed-citation xml:lang="ru">Hulzebos EH, Smit Y, Helders PP, van Meeteren NL. Preoperative physical therapy for elective cardiac surgery patients. Cochrane Database Syst Rev. 2012;11:CD010118. doi:10.1002/14651858.CD010118.pub2.</mixed-citation><mixed-citation xml:lang="en">Hulzebos EH, Smit Y, Helders PP, van Meeteren NL. Preoperative physical therapy for elective cardiac surgery patients. Cochrane Database Syst Rev. 2012;11:CD010118. doi:10.1002/14651858.CD010118.pub2.</mixed-citation></citation-alternatives></ref><ref id="cit43"><label>43</label><citation-alternatives><mixed-citation xml:lang="ru">Steinmetz J, Rasmussen LS. Peri-operative cognitive dysfunction and protection. Anaesthesia. 2016;71(Suppl 1):58-63. doi:10.1111/anae.13308.</mixed-citation><mixed-citation xml:lang="en">Steinmetz J, Rasmussen LS. Peri-operative cognitive dysfunction and protection. Anaesthesia. 2016;71(Suppl 1):58-63. doi:10.1111/anae.13308.</mixed-citation></citation-alternatives></ref><ref id="cit44"><label>44</label><citation-alternatives><mixed-citation xml:lang="ru">Juergens MC, Seekatz B, Moosdorf RG, et al. Illness beliefs before cardiac surgery predict disability, quality of life, and depression 3 months later. J Psychosom Res. 2010;68(6):553-60. doi:10.1016/j.jpsychores.2009.10.004.</mixed-citation><mixed-citation xml:lang="en">Juergens MC, Seekatz B, Moosdorf RG, et al. Illness beliefs before cardiac surgery predict disability, quality of life, and depression 3 months later. J Psychosom Res. 2010;68(6):553-60. doi:10.1016/j.jpsychores.2009.10.004.</mixed-citation></citation-alternatives></ref></ref-list><fn-group><fn fn-type="conflict"><p>The authors declare that there are no conflicts of interest present.</p></fn></fn-group></back></article>
