cardiovascularКардиоваскулярная терапия и профилактикаCardiovascular Therapy and Prevention1728-88002619-0125«SILICEA-POLIGRAF» LLC10.15829/1728-8800-2022-3272cardiovascular-3272Research ArticleОБЗОРЫ ЛИТЕРАТУРЫREVIEW ARTICLESРоль генетических факторов (биологии теломер хромосом) в кардиореабилитацииRole of genetic factors (biology of telomeres) in cardiac rehabilitationhttps://orcid.org/0000-0003-0484-9805АроновД. М.AronovD. M.

Давид Меерович Аронов — доктор медицинских наук, профессор, заслуженный деятель науки РФ, главный научный сотрудник, руководитель лаборатории кардиологической реабилитации.

Москва

Moscow

aronovdm@mail.ruhttps://orcid.org/0000-0001-6581-4521ДрапкинаО. М.DrapkinaO. M.

Оксана Михайловна Драпкина — доктор медицинских наук, профессор, академик РАН, директор.

Москва

Moscow

drapkina@bk.ruhttps://orcid.org/0000-0003-2250-5942БубноваМ. Г.BubnovaM. G.

Марина Геннадьевна Бубнова* — доктор медицинских наук, профессор, руководитель отдела реабилитации и вторичной профилактики сердечно-сосудистых заболеваний.

Москва. Тел.: +7 (903) 752-21-86

Moscow

mbubnova@gnicpm.ruФГБУ Национальный медицинский исследовательский центр терапии и профилактической медицины Минздрава РоссииNational Medical Research Center for Therapy and Preventive Medicine20220807202221632723272Copyright © Аронов Д.М., Драпкина О.М., Бубнова М.Г., 20222022Аронов Д.М., Драпкина О.М., Бубнова М.Г.Aronov D.M., Drapkina O.M., Bubnova M.G.Данная работа распространяется под лицензией Creative Commons Attribution 4.0.This work is licensed under a Creative Commons Attribution 4.0 License.https://cardiovascular.elpub.ru/jour/article/view/3272

Кардиореабилитация (КР) — один из эффективных видов медицинской помощи больным с сердечно-сосудистыми заболеваниями. В то же время выбор наиболее эффективных методов КР для конкретного пациента остается проблемой. Все большее число исследований посвящается применению генетических методов исследования здоровья человека. Особое внимание привлекает метод определения длины теломер хромосом. Цель обзора — анализ литературы, посвященной различным исследованиям о значимости оценки состояния теломер хромосом для характеристики здоровья человека и выбора эффективных методов КР. В статье обсуждаются вопросы, касающиеся связи длины теломер хромосом с кардиоваскулярными факторами риска, типом питания и психологическим статусом человека; дается оценка эффективности различных видов физических тренировок на генетическом уровне. При подготовке обзора проводился поиск публикаций в базах данных MEDLINE/PubMed, Scopus, Cochrane Library, PEDro, eLIBRARY и Google Scholar. При подготовке литературного обзора был проведен анализ публикаций за последние 14 лет. Представленные факты свидетельствуют о необходимости дальнейшего изучения и эффективного использования одного из генетических факторов защиты теломер хромосом в КР.

Cardiac rehabilitation (CR) is one of the effective healthcare types for cardiovascular patients. At the same time, the choice of the most effective CR methods for a particular patient remains a problem. An increasing number of studies are devoted to the application of genetic methods for studying human health. Particular attention is drawn to determining the telomere length. The review purpose was to analyze the literature on various studies on the significance of assessing the chromosome telomeres for characterizing human health and choosing effective CR methods. The article discusses issues related to the relationship between the telomere length and cardiovascular risk factors, dietary pattern, and psychological status of a person. We also assessed the effectiveness of various exercise types at the genetic level. In preparing the review, publications over the past 14 years were searched in the MEDLINE/PubMed, Scopus, Cochrane Library, PEDro, eLIBRARY, and Google Scholar databases. The presented facts indicate the need for further study and effective use of one of the genetic factors protecting chromosome telomeres in CR.

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The authors declare that there are no conflicts of interest present.