cardiovascularКардиоваскулярная терапия и профилактикаCardiovascular Therapy and Prevention1728-88002619-0125«SILICEA-POLIGRAF» LLC10.15829/1728-8800-2022-3362cardiovascular-3362Research ArticleРЕГИСТРЫ И ИССЛЕДОВАНИЯSTUDIES AND REGISTERSВлияние разовых и регулярных упражнений на артериальную жесткость и показатели отражения у пациентов с ишемической болезнью сердца: протокол рандомизированного клинического исследованияImpact of acute and chronic regular exercise on arterial stiffness and reflection measures in coronary artery disease patients: A Protocol for Randomized Clinical Trialhttps://orcid.org/0000-0001-6845-3194KapoorG.KapoorG.

PhD Scholar, Department of Physiotherapy.

Jaipur, +91987-240-07-11

Gaurav Kapoor - PhD Scholar, Department of  Physiotherapy.

Jaipur, Rajasthan, +91987-240-07-11

gauravkapoor00711@gmail.comhttps://orcid.org/0000-0002-7161-4558SwaroopА.SwaroopA.

Professor.

Jaipur

Avinash Swaroop - Professor.

Jaipur, Rajasthan

gauravkapoor00711@gmail.comhttps://orcid.org/0000-0001-6335-439XSinghS.SinghS.

Singh S. — Assistant professor, Department of Physiotherapy.

Patiala, Punjab

Sandeep Singh - Assistant professor, Department of Physiotherapy.

Patiala, Punjab

gauravkapoor00711@gmail.comJayoti Vidyapeeth Women’s UniversityJayoti Vidyapeeth Women’s UniversityPunjabi UniversityPunjabi University202204112022211033623362Copyright © Kapoor G., Swaroop А., Singh S., 20222022Kapoor G., Swaroop А., Singh S.Kapoor G., Swaroop A., Singh S.Данная работа распространяется под лицензией Creative Commons Attribution 4.0.This work is licensed under a Creative Commons Attribution 4.0 License.https://cardiovascular.elpub.ru/jour/article/view/3362

Атеросклеротическое поражение сосудистой стенки снижает эластичность артерий, что является независимым и неинвазивным предиктором будущей заболеваемости ишемической болезнью сердца и инсультом. Имеются ограниченные данные о положительном влиянии регулярных физических упражнений на артериальную жесткость у людей, страдающих сердечно-сосудистыми заболеваниями (ССЗ), особенно ишемической болезнью сердца (ИБС).

Цель

Цель. Определить влияние разовых и регулярных аэробных, силовых и комбинированных упражнений на артериальную и гемодинамическую функцию у пациентов с ИБС.

Материал и методы

Материал и методы. Данное проспективное, простое слепое, рандомизированное исследование будет изучать влияние упражнений на жесткость артерий. Исследование будет проводиться в высокоспециализированном стационаре в течение непрерывного периода в один год. Пациенты с ИБС (n=105) будут отобраны с использованием методов систематической выборки и случайным образом распределены в одну из четырех групп лечения с использованием компьютерной последовательности случайных чисел для возраста, пола и состояния здоровья ИБС (группа I: аэробные упражнения, группа II: упражнения с отягощениями, группа III: комбинированные аэробные упражнения и упражнения с отягощениями, группа IV: контроль) в соответствии с критериями включения и исключения. Все набранные субъекты будут проинформированы о процедуре оценки и вмешательства до заполнения формы согласия. Текущее исследование проводиться согласно рекомендациям SPIRIT (Standard Protocol Items: Recommendations for Interventional Trials).

Перспектива

Перспектива. Ожидается, что протокол исследования будет способствовать улучшению качества жизни наряду со снижением лекарственной зависимости у людей, страдающих ИБС. В дальнейшем это исследование будет полезно при разработке протокола упражнений для людей, страдающих ИБС.

Vascular stiffness due to arteriosclerosis reduces arterial elasticity which is as an independent and non-invasive predictor of future incidence of coronary heart disease and stroke. There is limited evidence of the benefits of regular exercise on arterial stiffness in populations suffering from cardiovascular diseases (CVD) especially coronary artery disease (CAD).

Aim

Aim. To determine the acute and chronic effects of aerobic, resistance and combined exercise on arterial and hemodynamic function in patients with CAD.

Material and methods

Material and methods. This study will be a prospective, single-blind, randomized study examining the effects of exercise on arterial stiffness. The study will be conducted at a tertiary care hospital for a continuous period of one year. Patients with CAD (n=105) will be selected using systematic sampling techniques and allocated randomly to one of the four treatment groups using computer-generated, random number sequence for age, sex and health status of CAD (Group-I: aerobic exercise, Group-II: resistance exercise, Group-III: combined aerobic and resistance exercise, and Group-IV: control) as per the inclusion and exclusion criteria. All recruited subjects will be informed about the assessment and intervention procedure before getting the consent form filled. This project followed the guidelines of standard protocol for randomized clinical trials (spirit).

Perspective

Perspective. It is expected that this study protocol shall through light and be helpful in better quality of life along with decline in drug dependency for the people suffering from CAD. Further this study will be valuable is designing exercise protocol for the people suffering from CAD.

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The authors declare that there are no conflicts of interest present.