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<article article-type="research-article" dtd-version="1.3" xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink" xmlns:xsi="http://www.w3.org/2001/XMLSchema-instance" xml:lang="ru"><front><journal-meta><journal-id journal-id-type="publisher-id">cardiovascular</journal-id><journal-title-group><journal-title xml:lang="ru">Кардиоваскулярная терапия и профилактика</journal-title><trans-title-group xml:lang="en"><trans-title>Cardiovascular Therapy and Prevention</trans-title></trans-title-group></journal-title-group><issn pub-type="ppub">1728-8800</issn><issn pub-type="epub">2619-0125</issn><publisher><publisher-name>«SILICEA-POLIGRAF» LLC</publisher-name></publisher></journal-meta><article-meta><article-id pub-id-type="doi">10.15829/1728-8800-2022-3454</article-id><article-id custom-type="elpub" pub-id-type="custom">cardiovascular-3454</article-id><article-categories><subj-group subj-group-type="heading"><subject>Research Article</subject></subj-group><subj-group subj-group-type="section-heading" xml:lang="ru"><subject>ИШЕМИЧЕСКАЯ БОЛЕЗНЬ СЕРДЦА</subject></subj-group><subj-group subj-group-type="section-heading" xml:lang="en"><subject>CORONARY HEART DISEASE</subject></subj-group></article-categories><title-group><article-title>Портрет пациента со стабильной ишемической болезнью сердца и нарушением мышечного статуса</article-title><trans-title-group xml:lang="en"><trans-title>Profile of a patient with stable coronary artery disease and impaired muscle status</trans-title></trans-title-group></title-group><contrib-group><contrib contrib-type="author" corresp="yes"><contrib-id contrib-id-type="orcid">https://orcid.org/0000-0002-7573-0636</contrib-id><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Коков</surname><given-names>А. Н.</given-names></name><name name-style="western" xml:lang="en"><surname>Kokov</surname><given-names>A. N.</given-names></name></name-alternatives><bio xml:lang="ru"><p>Кандидат медицинских наук, зав. лабораторией лучевых методов диагностики.</p><p>Кемерово</p></bio><bio xml:lang="en"><p>Kemerovo</p></bio><email xlink:type="simple">dr.kokov@mail.ru</email><xref ref-type="aff" rid="aff-1"/></contrib><contrib contrib-type="author" corresp="yes"><contrib-id contrib-id-type="orcid">https://orcid.org/0000-0003-3970-4294</contrib-id><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Масенко</surname><given-names>В. Л.</given-names></name><name name-style="western" xml:lang="en"><surname>Masenko</surname><given-names>A. I.</given-names></name></name-alternatives><bio xml:lang="ru"><p>Кандидат медицинских наук, научный сотрудник лаборатории лучевых методов диагностики.</p><p>Кемерово</p></bio><bio xml:lang="en"><p>Kemerovo</p></bio><email xlink:type="simple">dr.masenko@mail.ru</email><xref ref-type="aff" rid="aff-1"/></contrib><contrib contrib-type="author" corresp="yes"><contrib-id contrib-id-type="orcid">https://orcid.org/0000-0002-6004-4852</contrib-id><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Кареева</surname><given-names>А. И.</given-names></name><name name-style="western" xml:lang="en"><surname>Kareeva</surname><given-names>A. I.</given-names></name></name-alternatives><bio xml:lang="ru"><p>Младший научный сотрудник лаборатории лучевых методов диагностики.</p><p>Кемерово</p></bio><bio xml:lang="en"><p>Kemerovo</p></bio><email xlink:type="simple">dr.kareevaai@mail.ru</email><xref ref-type="aff" rid="aff-1"/></contrib><contrib contrib-type="author" corresp="yes"><contrib-id contrib-id-type="orcid">https://orcid.org/0000-0003-2384-5682</contrib-id><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Кривошапова</surname><given-names>К. Е.</given-names></name><name name-style="western" xml:lang="en"><surname>Krivoshapova</surname><given-names>K. E.</given-names></name></name-alternatives><bio xml:lang="ru"><p>Кандидат медицинских наук, научный сотрудник лаборатории коморбидности при сердечно-сосудистых заболеваниях.</p><p>Кемерово</p></bio><bio xml:lang="en"><p>Kemerovo</p></bio><email xlink:type="simple">ya.kristi89@yandex.ru</email><xref ref-type="aff" rid="aff-1"/></contrib><contrib contrib-type="author" corresp="yes"><contrib-id contrib-id-type="orcid">https://orcid.org/0000-0002-4642-3610</contrib-id><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Барбараш</surname><given-names>О. Л.</given-names></name><name name-style="western" xml:lang="en"><surname>Barbarash</surname><given-names>O. L.</given-names></name></name-alternatives><bio xml:lang="ru"><p>Доктор медицинских наук, профессор, академик РАН, директор.</p><p>Кемерово</p></bio><bio xml:lang="en"><p>Kemerovo</p></bio><email xlink:type="simple">olb61@mail.ru</email><xref ref-type="aff" rid="aff-1"/></contrib></contrib-group><aff-alternatives id="aff-1"><aff xml:lang="ru"><institution>ФГБНУ Научно-исследовательский институт комплексных проблем сердечно-сосудистых заболеваний</institution></aff><aff xml:lang="en"><institution>Research Institute for Complex Issues of Cardiovascular Diseases</institution></aff></aff-alternatives><pub-date pub-type="collection"><year>2022</year></pub-date><pub-date pub-type="epub"><day>19</day><month>01</month><year>2023</year></pub-date><volume>21</volume><issue>12</issue><fpage>3454</fpage><lpage>3454</lpage><permissions><copyright-statement>Copyright &amp;#x00A9; Коков А.Н., Масенко В.Л., Кареева А.И., Кривошапова К.Е., Барбараш О.Л., 2023</copyright-statement><copyright-year>2023</copyright-year><copyright-holder xml:lang="ru">Коков А.Н., Масенко В.Л., Кареева А.И., Кривошапова К.Е., Барбараш О.Л.</copyright-holder><copyright-holder xml:lang="en">Kokov A.N., Masenko A.I., Kareeva A.I., Krivoshapova K.E., Barbarash O.L.</copyright-holder><license xml:lang="ru" license-type="creative-commons-attribution" xlink:href="https://creativecommons.org/licenses/by/4.0/" xlink:type="simple"><license-p>Данная работа распространяется под лицензией Creative Commons Attribution 4.0.</license-p></license><license xml:lang="en" license-type="creative-commons-attribution" xlink:href="https://creativecommons.org/licenses/by/4.0/" xlink:type="simple"><license-p>This work is licensed under a Creative Commons Attribution 4.0 License.</license-p></license></permissions><self-uri xlink:href="https://cardiovascular.elpub.ru/jour/article/view/3454">https://cardiovascular.elpub.ru/jour/article/view/3454</self-uri><abstract><sec><title>Цель</title><p>Цель. Определить клинический портрет пациента со стабильной ишемической болезнью сердца (ИБС) и сопутствующим нарушением мышечного статуса.</p></sec><sec><title>Материал и методы</title><p>Материал и методы. В исследование включены 387 пациентов со стабильной ИБС, имеющих показания для открытой реваскуляризации миокарда. Количественная оценка мышечной ткани проводилась с использованием данных компьютерной томографии. Выполнен сравнительный анализ показателей клинико-анамнестической характеристики групп пациентов с саркопенией (n=152) и с нормальным мышечным статусом (n=235).</p></sec><sec><title>Результаты</title><p>Результаты. Признаки саркопении выявлены у 39,3% пациентов со стабильной ИБС. В группе саркопении и группе с нормальным мышечным статусом отмечалось преобладание лиц мужского пола — 86,2 и 64,7% (р=0,01), наличие гиперхолестеринемии — 51,3 и 31,1% (р=0,02), сахарного диабета (СД) 2 типа — 21,1 и 28,1% (р=0,06), многососудистого поражения коронарных артерий — 25,6 и 17,8% случаев (р=0,018), соответственно. При саркопении отмечали в 4 раза более длительный анамнез СД (р=0,01) и в 2,3 раза бóльшую длительность ИБС (р=0,03). Частота ожирения при саркопении меньше в 3,4 раза (р=0,003). Корреляционный анализ показал связь мышечного статуса с возрастом (r=-0,674; p=0,002), длительностью анамнеза ИБС (r=-0,582; p=0,001) и СД (r=-0,748; p&lt;0,001).</p></sec><sec><title>Заключение</title><p>Заключение. Клинико-анамнестический образ пациента со стабильной ИБС и саркопенией характеризуется ассоциацией пониженной мышечной массы с мужским полом, гиперхолестеринемией, многососудистым поражением коронарного русла, длительным анамнезом СД 2 типа и стенокардии.</p></sec></abstract><trans-abstract xml:lang="en"><sec><title>Aim</title><p>Aim. To determine the clinical profile of a patient with stable coronary artery disease (CAD) and impaired muscle status.</p></sec><sec><title>Material and methods</title><p>Material and methods. The study included 387 patients with stable CAD who had indications for open myocardial revascularization. Quantification of muscle tissue was carried out using computed tomography. Comparative analysis of clinical and anamnestic characteristics of groups of patients with sarcopenia (n=152) and those with normal muscle status (n=235) was performed.</p></sec><sec><title>Results</title><p>Results. Signs of sarcopenia were found in 39,3% of patients with stable CAD. In the group of sarcopenia and the group with normal muscle status, there was a predominance of males — 86,2 and 64,7% (p=0,01), the presence of hypercholesterolemia — 51,3 and 31,1% (p=0,02), type 2 diabetes — 21,1 and 28,1% (p=0,06), multivessel CAD — 25,6 and 17,8% of cases (p=0,018), respectively. In sarcopenia, a 4 times longer history of diabetes was noted (p=0,01) and a 2,3 times longer duration of CAD (p=0,03). The prevalence of obesity in sarcopenia was 3,4 times less (p=0,003). Correlation analysis showed the relationship of muscle status with age (r=-0,674; p=0,002), duration of CAD history (r=-0,582; p=0,001) and diabetes (r=-0,748; p&lt;0,001).</p></sec><sec><title>Conclusion</title><p>Conclusion. The clinical and anamnestic profile of a patient with stable CAD and sarcopenia is characterized by an association of decreased muscle mass with male sex, hypercholesterolemia, multivessel coronary CAD, a long-term history of type 2 diabetes and angina.</p></sec></trans-abstract><kwd-group xml:lang="ru"><kwd>саркопения</kwd><kwd>компьютерная томография</kwd><kwd>ишемическая болезнь сердца</kwd><kwd>клинический портрет</kwd></kwd-group><kwd-group xml:lang="en"><kwd>sarcopenia</kwd><kwd>computed tomography</kwd><kwd>coronary artery disease</kwd><kwd>clinical profile</kwd></kwd-group><funding-group><funding-statement xml:lang="ru">Исследование выполнено в рамках гранта РНФ № 22-15-00305 "Патофизиологические особенности формирования остеосаркопенического ожирения при мультифокальном атеросклерозе как маркера биологического старения"</funding-statement><funding-statement xml:lang="en">The study was carried out within the Russian Science Foundation grant № 22-15-00305 "Pathophysiological features of the formation of osteosarcopenic obesity in multifocal atherosclerosis as a marker of biological aging"</funding-statement></funding-group></article-meta></front><back><ref-list><title>References</title><ref id="cit1"><label>1</label><citation-alternatives><mixed-citation xml:lang="ru">Вегнер Е. 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