<?xml version="1.0" encoding="UTF-8"?>
<!DOCTYPE article PUBLIC "-//NLM//DTD JATS (Z39.96) Journal Publishing DTD v1.3 20210610//EN" "JATS-journalpublishing1-3.dtd">
<article article-type="research-article" dtd-version="1.3" xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink" xmlns:xsi="http://www.w3.org/2001/XMLSchema-instance" xml:lang="ru"><front><journal-meta><journal-id journal-id-type="publisher-id">cardiovascular</journal-id><journal-title-group><journal-title xml:lang="ru">Кардиоваскулярная терапия и профилактика</journal-title><trans-title-group xml:lang="en"><trans-title>Cardiovascular Therapy and Prevention</trans-title></trans-title-group></journal-title-group><issn pub-type="ppub">1728-8800</issn><issn pub-type="epub">2619-0125</issn><publisher><publisher-name>«SILICEA-POLIGRAF» LLC</publisher-name></publisher></journal-meta><article-meta><article-id pub-id-type="doi">10.15829/1728-8800-2023-3473</article-id><article-id custom-type="elpub" pub-id-type="custom">cardiovascular-3473</article-id><article-categories><subj-group subj-group-type="heading"><subject>Research Article</subject></subj-group><subj-group subj-group-type="section-heading" xml:lang="ru"><subject>АРТЕРИАЛЬНАЯ ГИПЕРТОНИЯ</subject></subj-group><subj-group subj-group-type="section-heading" xml:lang="en"><subject>ARTERIAL HYPERTENSION</subject></subj-group></article-categories><title-group><article-title>Сравнительный анализ  значений индексов  артериальной жесткости  START и CAVI у больных артериальной гипертензией</article-title><trans-title-group xml:lang="en"><trans-title>Comparative analysis of START and CAVI arterial stiffness scores  in hypertensive patients</trans-title></trans-title-group></title-group><contrib-group><contrib contrib-type="author" corresp="yes"><contrib-id contrib-id-type="orcid">https://orcid.org/0000-0002-0963-4793</contrib-id><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Сумин</surname><given-names>А. Н.</given-names></name><name name-style="western" xml:lang="en"><surname>Sumin</surname><given-names>A. N.</given-names></name></name-alternatives><bio xml:lang="ru"><p>Сумин Алексей Николаевич — доктор медицинских наук, заведующий лабораторией коморбидности при сердечно-сосудистых заболеваниях отдела клинической кардиологии.</p><p>Кемерово</p></bio><bio xml:lang="en"><p>Kemerovo</p></bio><email xlink:type="simple">an_sumin@mail.ru</email><xref ref-type="aff" rid="aff-1"/></contrib><contrib contrib-type="author" corresp="yes"><contrib-id contrib-id-type="orcid">https://orcid.org/0000-0002-4108-164X</contrib-id><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Щеглова</surname><given-names>А. В.</given-names></name><name name-style="western" xml:lang="en"><surname>Shcheglova</surname><given-names>A. V.</given-names></name></name-alternatives><bio xml:lang="ru"><p>Щеглова Анна Викторовна — кандидат медицинских наук, научный сотрудник лаборатории коморбидности при сердечно-сосудистых заболеваниях отдела клинической кардиологии.</p><p>Кемерово</p></bio><bio xml:lang="en"><p>Kemerovo</p></bio><email xlink:type="simple">nura.karpovitch@yandex.ru</email><xref ref-type="aff" rid="aff-2"/></contrib><contrib contrib-type="author" corresp="yes"><contrib-id contrib-id-type="orcid">https://orcid.org/0000-0003-0928-2430</contrib-id><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Бахолдин</surname><given-names>И. Б.</given-names></name><name name-style="western" xml:lang="en"><surname>Bakholdin</surname><given-names>I. B.</given-names></name></name-alternatives><bio xml:lang="ru"><p>Бахолдин Игорь Борисович — доктор физико-математических наук, старший научный сотрудник.</p><p>Москва</p></bio><bio xml:lang="en"><p>Moscow</p></bio><email xlink:type="simple">ibbakh@yandex.ru</email><xref ref-type="aff" rid="aff-3"/></contrib></contrib-group><aff-alternatives id="aff-1"><aff xml:lang="ru"><institution>Научно-исследовательский институт комплексных проблем сердечно-сосудистых заболеваний</institution></aff><aff xml:lang="en"><institution>Research Institute for Complex Issues of Cardiovascular Diseases</institution></aff></aff-alternatives><aff-alternatives id="aff-2"><aff xml:lang="ru"><institution>Научно-исследовательский институт комплексных проблем сердечно-сосудистых заболеваний</institution></aff><aff xml:lang="en"><institution>Research Institute for Complex Issues of Cardiovascular Diseases</institution></aff></aff-alternatives><aff-alternatives id="aff-3"><aff xml:lang="ru"><institution>Федеральный  исследовательский  центр  Институт  прикладной  математики  им.  М.В. Келдыша  Российской  академии  наук</institution></aff><aff xml:lang="en"><institution>Federal Research Center of the Keldysh Institute of Applied Mathematics</institution></aff></aff-alternatives><pub-date pub-type="collection"><year>2023</year></pub-date><pub-date pub-type="epub"><day>09</day><month>04</month><year>2023</year></pub-date><volume>22</volume><issue>3</issue><fpage>3473</fpage><lpage>3473</lpage><permissions><copyright-statement>Copyright &amp;#x00A9; Сумин А.Н., Щеглова А.В., Бахолдин И.Б., 2023</copyright-statement><copyright-year>2023</copyright-year><copyright-holder xml:lang="ru">Сумин А.Н., Щеглова А.В., Бахолдин И.Б.</copyright-holder><copyright-holder xml:lang="en">Sumin A.N., Shcheglova A.V., Bakholdin I.B.</copyright-holder><license xml:lang="ru" license-type="creative-commons-attribution" xlink:href="https://creativecommons.org/licenses/by/4.0/" xlink:type="simple"><license-p>Данная работа распространяется под лицензией Creative Commons Attribution 4.0.</license-p></license><license xml:lang="en" license-type="creative-commons-attribution" xlink:href="https://creativecommons.org/licenses/by/4.0/" xlink:type="simple"><license-p>This work is licensed under a Creative Commons Attribution 4.0 License.</license-p></license></permissions><self-uri xlink:href="https://cardiovascular.elpub.ru/jour/article/view/3473">https://cardiovascular.elpub.ru/jour/article/view/3473</self-uri><abstract><sec><title>Цель</title><p>Цель. Сопоставить новый индекс артериальной  жесткости START и показатель  сердечно-лодыжечного  сосудистого  индекса (CAVI) у больных артериальной гипертензией (АГ).</p></sec><sec><title>Материал и методы</title><p>Материал и методы. Обследованы 709 человек с АГ в возрасте  от 24 до 64 лет методом объемной сфигмографии на аппарате VaSera VS-1000 (Fukuda Denshi, Япония). Изучались значения CAVI и START, полученного ретроспективно по скорости пульсовой волны и показателям  артериального  давления при помощи оnline калькулятора. Результаты. Медиана индекса CAVI была в пределах нормальных значений (&lt;9,0): 7,5 (6,6; 8,4) справа и 7,4 (6,5; 8,4) слева.  Медиана индекса START составила 6,25 (5,0; 7,55) справа и 6,4 (5,1; 7,8) слева. Для молодых лиц (21-30 лет) медиана индекса START составила 4,47, для индекса CAVI — 6,25 (р&gt;0,05). У лиц старшей возрастной  группы (61-70 лет) медиана  индекса START составила  7,27, для индекса CAVI — 8,4 (р&gt;0,05). Динамика роста индекса START с возрастом была выше на 38,5%, чем индекса CAVI на 25,6% (р=0,034). Отмечена высокая степень корреляции CAVI и START (r=0,823, р&lt;0,001). Показатели  ассоциировались  с  возрастом   (r=0,412  для  CAVI и r=0,355 для START; p&lt;0,001),  стажем курения (r=0,390 и r=0,361; p&lt;0,001),  скоростью клубочковой фильтрации (r=-0,317 и r=-0,318; p&lt;0,001),  индексом массы тела (r=-0,176 и r=-0,185; p=0,001). Для индекса CAVI связь выявлена с уровнем глюкозы (r=0,192; p&lt;0,001) и малоподвижным образом  жизни (r=-0,157; p=0,04), для индекса START — с уровнем креатинина (r=0,143; p=0,01).</p></sec><sec><title>Заключение</title><p>Заключение. У  больных АГ  отмечена  высокая  степень  корреляции нового индекса START с индексом CAVI (r=0,823, р&lt;0,001). Показатели имели схожие ассоциации  с факторами риска, что является важным для последующего практического применения индекса START.</p></sec></abstract><trans-abstract xml:lang="en"><sec><title>Aim</title><p>Aim.  To compare  the  novel arterial stiffness  index START and  the cardio-ankle vascular index (CAVI) in hypertensive (HTN) patients. Material and methods. A total of 709 people  with HTN aged  24 to 64 years  were  examined by volume sphygmography  using VaSera VS-1000 (Fukuda Denshi, Japan).  CAVI  and  START values obtained retrospectively  from pulse  wave velocity and  blood pressure  were studied using an online calculator.</p></sec><sec><title>Results</title><p>Results. The median CAVI score was within the normal range (&lt;9,0): 7,5 (6,6; 8,4) on the right and 7,4 (6,5; 8,4) on the left. The median of the START index was 6,25 (5,0; 7,55) on the right and 6,4 (5,1; 7,8) on the left. For young people (21-30 years old), the median START score was 4,47, for the CAVI index — 6,25 (p&gt;0,05). In the older age group (61-70 years), the median START index was 7,27, for the CAVI index — 8,4 (p&gt;0,05).  The growth pattern of the START score with age was higher by 38,5% than the CAVI index by 25,6% (p=0,034). A high degree  of correlation between CAVI and START was noted (r=0,823, p&lt;0,001).  Parameters were associated with age (r=0,412 for CAVI and r=0,355 for START; p&lt;0,001), smoking duration (r=0,390 and r=0,361; p&lt;0,001), glomerular filtration rate (r=-0,317 and r= -0,318; p&lt;0,001), body mass index (r=-0,176 and r=-0,185; p=0,001). For the CAVI index, a relationship was found with the glucose level (r=0,192; p&lt;0,001) and a sedentary  lifestyle (r=-0,157; p=0,04), while for the START index — with the creatinine level (r=0,143; p=0,01).</p></sec><sec><title>Conclusion</title><p>Conclusion.  Patients  with hypertension  showed  a high correlation between   the  novel  START index  and  the  CAVI   score   (r=0,823, p&lt;0,001).  The indicators  had similar associations  with risk factors, which is important for the  subsequent practical  application of the START index.</p></sec></trans-abstract><kwd-group xml:lang="ru"><kwd>сердечно-лодыжечный сосудистый индекс</kwd><kwd>артериальная  жесткость</kwd><kwd>индекс артериальной  жесткости START</kwd><kwd>факторы риска</kwd><kwd>артериальная  гипертензия</kwd><kwd>скорость  пульсовой волны</kwd></kwd-group><kwd-group xml:lang="en"><kwd>cardio-ankle vascular index</kwd><kwd>arterial stiffness</kwd><kwd>START arterial stiffness index</kwd><kwd>risk factors</kwd><kwd>hypertension</kwd><kwd>pulse wave velocity</kwd></kwd-group></article-meta></front><back><ref-list><title>References</title><ref id="cit1"><label>1</label><citation-alternatives><mixed-citation xml:lang="ru">Mitchell GF, Hwang SJ, Vasan RS, et al. Arterial stiffness and cardiovascular events: the Framingham heart study. Circulation. 2010;121(4):505-11. doi:10.1161/CIRCULATIONAHA.109.886655.0.</mixed-citation><mixed-citation xml:lang="en">Mitchell GF, Hwang SJ, Vasan RS, et al. Arterial stiffness and cardiovascular events: the Framingham heart study. Circulation. 2010;121(4):505-11. doi:10.1161/CIRCULATIONAHA.109.886655.0.</mixed-citation></citation-alternatives></ref><ref id="cit2"><label>2</label><citation-alternatives><mixed-citation xml:lang="ru">Васюк Ю. А., Иванова С. В., Школьник Е.Л. и др. Согласованное мнение российских экспертов по оценке артериальной жесткости в клинической практике. Кардиоваскулярная терапия и профилактика. 2016;15(2):4-19. doi:10.15829/1728-8800-2016-2-4-19.</mixed-citation><mixed-citation xml:lang="en">Vasyuk YuA, Ivanova SV, Shkolnik EL, et al. Consensus of Russian experts on the evaluation of arterial stiffness in clinical practice. Cardiovascular Therapy and Prevention. 2016;15(2):4-19. (In Russ.) doi:10.15829/1728-8800-2016-2-4-19.</mixed-citation></citation-alternatives></ref><ref id="cit3"><label>3</label><citation-alternatives><mixed-citation xml:lang="ru">Хромова А. А., Салямова Л. И., Квасова О. Г. и др. Традиционные факторы риска и состояние артериального русла у пациентов с ишемической болезнью сердца моложе и старше 50 лет. Кардиоваскулярная терапия и профилактика. 2020;19(4):2541. doi:10.15829/1728-8800-2020-2541.</mixed-citation><mixed-citation xml:lang="en">Khromova AA, Salyamova LI, Kvasova OG, et al. Conventional risk factors and arterial bed parameters in patients with coronary artery disease younger and older than 50 years. Cardiovascular Therapy and Prevention. 2020;19(4):2541. (In Russ.). doi:10.15829/1728-8800-2020-2541.</mixed-citation></citation-alternatives></ref><ref id="cit4"><label>4</label><citation-alternatives><mixed-citation xml:lang="ru">Shirai K, Utino J, Otsuka K, et al. A novel blood pressureindependent arterial wall stiffness parameter; cardio-ankle vascular index (CAVI). J Atheroscler Thromb. 2006;13(2):101-7. doi:10.5551/jat.13.101.</mixed-citation><mixed-citation xml:lang="en">Shirai K, Utino J, Otsuka K, et al. A novel blood pressureindependent arterial wall stiffness parameter; cardio-ankle vascular index (CAVI). J Atheroscler Thromb. 2006;13(2):101-7. doi:10.5551/jat.13.101.</mixed-citation></citation-alternatives></ref><ref id="cit5"><label>5</label><citation-alternatives><mixed-citation xml:lang="ru">Spronck B, Avolio AP, Tan I, et al. Arterial stiffness index beta and cardio-ankle vascular index inherently depend on blood pressure but can be readily corrected. J Hypertens. 2017;35(1):98-104. doi:10.1097/HJH.0000000000001132.</mixed-citation><mixed-citation xml:lang="en">Spronck B, Avolio AP, Tan I, et al. Arterial stiffness index beta and cardio-ankle vascular index inherently depend on blood pressure but can be readily corrected. J Hypertens. 2017;35(1):98-104. doi:10.1097/HJH.0000000000001132.</mixed-citation></citation-alternatives></ref><ref id="cit6"><label>6</label><citation-alternatives><mixed-citation xml:lang="ru">Бахолдин И.Б., Милягин В.А., Талов А.В. и др. Индекс STELARI START — новый перспективный показатель сосудистой жесткости. Вестник смоленской государственной медицинской академии. 2022;21(3):96-103. doi:10.37903/vsgma.2022.3.11.</mixed-citation><mixed-citation xml:lang="en">Bakholdin IB, Milyagin VA, Talov AV, et al. The stelari START index is a new promising indicator of vascular stiffness. Bulletin of the Smolensk State Medical Academy. 2022;21(3):96-103. (In Russ.) doi:10.37903/vsgma.2022.3.11.</mixed-citation></citation-alternatives></ref><ref id="cit7"><label>7</label><citation-alternatives><mixed-citation xml:lang="ru">Shirai K, Song M, Suzuki J, et al. Contradictory effects of β1 and α1- aderenergic receptor blockers on cardio-ankle vascular stiffness index (CAVI) — CAVI independent of blood pressure. J Atheroscler Thromb. 2011;18(1):49-55. doi:10.5551/jat.3582.</mixed-citation><mixed-citation xml:lang="en">Shirai K, Song M, Suzuki J, et al. Contradictory effects of β1 and α1- aderenergic receptor blockers on cardio-ankle vascular stiffness index (CAVI) — CAVI independent of blood pressure. J Atheroscler Thromb. 2011;18(1):49-55. doi:10.5551/jat.3582.</mixed-citation></citation-alternatives></ref><ref id="cit8"><label>8</label><citation-alternatives><mixed-citation xml:lang="ru">Shirai K, Shimizu K, Takata M, et al. Independency of the cardio-ankle vascular index from blood pressure at the time of measurement. J Hypertens. 2017;35(7):1521-3. doi:10.1097/HJH.0000000000001349.</mixed-citation><mixed-citation xml:lang="en">Shirai K, Shimizu K, Takata M, et al. Independency of the cardio-ankle vascular index from blood pressure at the time of measurement. J Hypertens. 2017;35(7):1521-3. doi:10.1097/HJH.0000000000001349.</mixed-citation></citation-alternatives></ref><ref id="cit9"><label>9</label><citation-alternatives><mixed-citation xml:lang="ru">Научно-организационный комитет проекта ЭССЕ-РФ. Эпидемиология сердечно-сосудистых заболеваний в различных регионах России (ЭССЕ-РФ). Обоснование и дизайн исследования. Профилактическая медицина. 2013;16(6):25-34.</mixed-citation><mixed-citation xml:lang="en">Scientific and organizing committee of the project ESSE-RF. Epidemiology of cardiovascular diseases in different regions of Russia (ESSE-RF). The rationale for and design of the study. Profilakticheskaya Meditsina. 2013;16(6):25-34. (In Russ.)</mixed-citation></citation-alternatives></ref><ref id="cit10"><label>10</label><citation-alternatives><mixed-citation xml:lang="ru">Сумин А. Н., Щеглова А. В., Фёдорова Н. В. и др. Сердечно-лодыжечный сосудистый индекс у больных артериальной гипертензией. Доктор.Ру. 2016;11(128):28-32.</mixed-citation><mixed-citation xml:lang="en">Sumin AN, Shcheglova AV, Fedorova NV, et al. Cardio-ankle vascular index in patients with arterial hypertension. Doctor.Ru. 2016;11(128):28-32. (In Russ.)</mixed-citation></citation-alternatives></ref><ref id="cit11"><label>11</label><citation-alternatives><mixed-citation xml:lang="ru">Бахолдин И. Б. Теория и классификация обратимых структур разрывов в моделях гидродинамического типа. ПММ. 2014;78(6):833-52.</mixed-citation><mixed-citation xml:lang="en">Bakholdin IB. Theory and classification of reversible structures of discontinuities in hydrodynamic type models. PMM. 2014;78(6):833-52. (In Russ.)</mixed-citation></citation-alternatives></ref><ref id="cit12"><label>12</label><citation-alternatives><mixed-citation xml:lang="ru">Бахолдин И. Б. Применение теории обратимых разрывов для исследования уравнений, описывающих волны в трубах с упругими стенками. Прикладная математика и механика. 2017;81(5):593-609.</mixed-citation><mixed-citation xml:lang="en">Bakholdin IB. Application of the theory of reversible discontinuities for the study of equations describing waves in pipes with elastic walls. Applied Mathematics and Mechanics.2017;81(5):593-609. (In Russ.)</mixed-citation></citation-alternatives></ref><ref id="cit13"><label>13</label><citation-alternatives><mixed-citation xml:lang="ru">Shirai K, Suzuki K, Tsuda S, et al. Comparison of CardioAnkle Vascular Index (CAVI) and CAVI0 in Large Healthy and Hypertensive Populations. J Atheroscler Thromb. 2019;26(7):603-15. doi:10.5551/jat.48314.</mixed-citation><mixed-citation xml:lang="en">of CardioAnkle Vascular Index (CAVI) and CAVI0 in Large Healthy and Hypertensive Populations. J Atheroscler Thromb. 2019;26(7):603-15. doi:10.5551/jat.48314.</mixed-citation></citation-alternatives></ref><ref id="cit14"><label>14</label><citation-alternatives><mixed-citation xml:lang="ru">Nagayama D, Fujishiro K, Miyoshi T, et al. Predictive ability of arterial stiffness parameters for renal function decline: a retrospective cohort study comparing cardio-ankle vascular index, pulse wave velocity and cardio-ankle vascular index 0. J Hypertens. 2022;40(7):1294-302. doi:10.1097/HJH.0000000000003137.</mixed-citation><mixed-citation xml:lang="en">Nagayama D, Fujishiro K, Miyoshi T, et al. Predictive ability of arterial stiffness parameters for renal function decline: a retrospective cohort study comparing cardio-ankle vascular index, pulse wave velocity and cardio-ankle vascular index 0. J Hypertens. 2022;40(7):1294-302. doi:10.1097/HJH.0000000000003137.</mixed-citation></citation-alternatives></ref><ref id="cit15"><label>15</label><citation-alternatives><mixed-citation xml:lang="ru">Takahashi K, Yamamoto T, Tsuda S, et al. The Background of Calculating CAVI: Lesson from the Discrepancy Between CAVI and CAVI0. Vasc Health Risk Manag. 2020;16:193-201. doi:10.2147/VHRM.S223330.</mixed-citation><mixed-citation xml:lang="en">Takahashi K, Yamamoto T, Tsuda S, et al. The Background of Calculating CAVI: Lesson from the Discrepancy Between CAVI and CAVI0. Vasc Health Risk Manag. 2020;16:193-201. doi:10.2147/VHRM.S223330.</mixed-citation></citation-alternatives></ref><ref id="cit16"><label>16</label><citation-alternatives><mixed-citation xml:lang="ru">Saiki A, Ohira M, Yamaguchi T, et al. New Horizons of Arterial Stiffness Developed Using Cardio-Ankle Vascular Index (CAVI). J Atheroscler Thromb. 2020;27(8):732-48. doi:10.5551/jat.RV17043.</mixed-citation><mixed-citation xml:lang="en">Saiki A, Ohira M, Yamaguchi T, et al. New Horizons of Arterial Stiffness Developed Using Cardio-Ankle Vascular Index (CAVI). J Atheroscler Thromb. 2020;27(8):732-48. doi:10.5551/jat.RV17043.</mixed-citation></citation-alternatives></ref><ref id="cit17"><label>17</label><citation-alternatives><mixed-citation xml:lang="ru">Wang H, Liu J, Zhao H, et al. Relationship between cardio-ankle vascular index and plasma lipids in hypertension subjects. J Hum Hypertens. 2015;29(2):105-8. doi:10.1038/jhh.2014.37.</mixed-citation><mixed-citation xml:lang="en">Wang H, Liu J, Zhao H, et al. Relationship between cardio-ankle vascular index and plasma lipids in hypertension subjects. J Hum Hypertens. 2015;29(2):105-8. doi:10.1038/jhh.2014.37.</mixed-citation></citation-alternatives></ref><ref id="cit18"><label>18</label><citation-alternatives><mixed-citation xml:lang="ru">Sumin AN, Shcheglova AV, Ivanov SV, et al. Long-Term Prognosis after Coronary Artery Bypass Grafting: The Impact of Arterial Stiffness and Multifocal Atherosclerosis. J Clin Med. 2022;11(15):4585. doi:10.3390/jcm11154585.</mixed-citation><mixed-citation xml:lang="en">Sumin AN, Shcheglova AV, Ivanov SV, et al. Long-Term Prognosis after Coronary Artery Bypass Grafting: The Impact of Arterial Stiffness and Multifocal Atherosclerosis. J Clin Med. 2022;11(15):4585. doi:10.3390/jcm11154585.</mixed-citation></citation-alternatives></ref><ref id="cit19"><label>19</label><citation-alternatives><mixed-citation xml:lang="ru">Nagayama D, Yamaguchi T, Saiki A, et al. High serum uric acid is associated with increased cardio-ankle vascular index (CAVI) in healthy Japanese subjects: a cross-sectional study. Atherosclerosis. 2015;239(1):163-8. doi:10.1016/j.atherosclerosis.2015.01.011.</mixed-citation><mixed-citation xml:lang="en">Nagayama D, Yamaguchi T, Saiki A, et al. High serum uric acid is associated with increased cardio-ankle vascular index (CAVI) in healthy Japanese subjects: a cross-sectional study. Atherosclerosis. 2015;239(1):163-8. doi:10.1016/j.atherosclerosis.2015.01.011.</mixed-citation></citation-alternatives></ref><ref id="cit20"><label>20</label><citation-alternatives><mixed-citation xml:lang="ru">Олейников В. Э., Хромова А.А., Абрамова Е. А. и др. Влияние высокоэффективной липидснижающей терапии на локальную сосудистую ригидность и симптомы хронической сердечной недостаточности при постинфарктном кардиосклерозе. Артериальная гипертензия. 2020;26(1):75-84. doi:10.18705/1607-419X-2020-26-1-75-84.</mixed-citation><mixed-citation xml:lang="en">Oleynikov VE, Khromova AA, Abramova EA, et al. Highly effective lipid-lowering therapy on local vascular stiffness and symptoms of chronic heart failure in patients with postinfarction cardiosclerosis. Arterial Hypertension. 2020;26(1):75-84. (In Russ.) doi:10.18705/1607-419X-2020-26-1-75-84.</mixed-citation></citation-alternatives></ref><ref id="cit21"><label>21</label><citation-alternatives><mixed-citation xml:lang="ru">Kobayashi R, Sato K, Takahashi T, et al. Effects of a shortterm increase in physical activity on arterial stiffness during hyperglycemia. J Clin Biochem Nutr. 2020;66(3):238-44. doi:10.3164/jcbn.19-69.</mixed-citation><mixed-citation xml:lang="en">Kobayashi R, Sato K, Takahashi T, et al. Effects of a shortterm increase in physical activity on arterial stiffness during hyperglycemia. J Clin Biochem Nutr. 2020;66(3):238-44. doi:10.3164/jcbn.19-69.</mixed-citation></citation-alternatives></ref><ref id="cit22"><label>22</label><citation-alternatives><mixed-citation xml:lang="ru">Zuo C, Bo S, Li Q, et al. The Effect of Whole-Body Traditional and Functional Resistance Training on CAVI and Its Association With Muscular Fitness in Untrained Young Men. Front Physiol. 2022;13:888048. doi:10.3389/fphys.2022.888048.</mixed-citation><mixed-citation xml:lang="en">Zuo C, Bo S, Li Q, et al. The Effect of Whole-Body Traditional and Functional Resistance Training on CAVI and Its Association With Muscular Fitness in Untrained Young Men. Front Physiol. 2022;13:888048. doi:10.3389/fphys.2022.888048.</mixed-citation></citation-alternatives></ref><ref id="cit23"><label>23</label><citation-alternatives><mixed-citation xml:lang="ru">Ротарь О. П., Толкунова К. М. Сосудистое старение в концепциях EVA и SUPERNOVA: непрерывный поиск повреждающих и протективных факторов. Артериальная гипертензия. 2020;26(2):133-45. doi:10.18705/1607-419X-2020-26-2-133-145.</mixed-citation><mixed-citation xml:lang="en">Rotar OP, Tolkunova KM. EVA and SUPERNOVA concepts of vascular aging: ongoing research on damaging and protective risk factors. Arterial Hypertension. 2020;26(2):133-45. (In Russ.) doi:10.18705/1607-419X-2020-26-2-133-145.</mixed-citation></citation-alternatives></ref><ref id="cit24"><label>24</label><citation-alternatives><mixed-citation xml:lang="ru">Толкунова К. М., Ротарь О. П., Ерина А. М. и др. Концепция "супернормального" сосудистого старения — распространенность и детерминанты на популяционном уровне (в рамках ЭССЕ-РФ). Артериальная гипертензия. 2020;26(2):170-83. doi:10.18705/1607-419X-2020-26-2-170-183.</mixed-citation><mixed-citation xml:lang="en">Tolkunova KM, Rotar OP, Erina AM, et al. Supernormal vascular aging — prevalence and determinants at population level (the ESSE-RF data). Arterial Hypertension. 2020;26(2):170-83. (In Russ.) doi:10.18705/1607-419X-2020-26-2-170-183.</mixed-citation></citation-alternatives></ref><ref id="cit25"><label>25</label><citation-alternatives><mixed-citation xml:lang="ru">Бурко Н. В., Авдеева И. В., Олейников В. Э. и др. Концепция раннего сосудистого старения. Рациональная Фармакотерапия в Кардиологии. 2019;15(5):742-9. doi:10.20996/1819-6446-2019-15-5-742-749.</mixed-citation><mixed-citation xml:lang="en">Burko NV, Avdeeva IV, Oleynikov VE, et al. The Concept of Early Vascular Aging. Rational Pharmacotherapy in Cardiology. 2019;15(5):742-749. doi:10.20996/1819-6446-2019-15-5-742-749.</mixed-citation></citation-alternatives></ref><ref id="cit26"><label>26</label><citation-alternatives><mixed-citation xml:lang="ru">Сумин А. Н., Щеглова А. В. Оценка артериальной жесткости с помощью сердечно-лодыжечного сосудистого индекса — что мы знаем, и к чему стремимся. Рациональная Фармакотерапия в Кардиологии. 2021;17(4):619-27. doi:10.20996/1819-6446-2021-08-09.</mixed-citation><mixed-citation xml:lang="en">Sumin AN, Shcheglova AV. Assessment of Arterial stiffness using the cardio-ankle vascular index — what we know and what we strive for. Rational Pharmacotherapy in Cardiology. 2021;17(4):619-27. (In Russ.) doi:10.20996/1819-6446-2021-08-09.</mixed-citation></citation-alternatives></ref><ref id="cit27"><label>27</label><citation-alternatives><mixed-citation xml:lang="ru">Kiuchi S, Hisatake S, Kawasaki M, et al. Addition of a renin-angiotensin-aldosterone system inhibitor to a calcium channel blocker ameliorates arterial stiffness. Clin Pharmacol. 2015;7:97-102. doi:10.2147/CPAA.S81880.</mixed-citation><mixed-citation xml:lang="en">Kiuchi S, Hisatake S, Kawasaki M, et al. Addition of a renin-angiotensin-aldosterone system inhibitor to a calcium channel blocker ameliorates arterial stiffness. Clin Pharmacol. 2015;7:97-102. doi:10.2147/CPAA.S81880.</mixed-citation></citation-alternatives></ref><ref id="cit28"><label>28</label><citation-alternatives><mixed-citation xml:lang="ru">Shirai K, Saiki A, Nagayama D, et al. The Role of Monitoring Arterial Stiffness with Cardio-Ankle Vascular Index in the Control of Lifestyle-Related Diseases. Pulse (Basel). 2015 Sep;3(2):118-33. doi:10.1159/000431235.</mixed-citation><mixed-citation xml:lang="en">Shirai K, Saiki A, Nagayama D, et al. The Role of Monitoring Arterial Stiffness with Cardio-Ankle Vascular Index in the Control of Lifestyle-Related Diseases. Pulse (Basel). 2015 Sep;3(2):118-33. doi:10.1159/000431235.</mixed-citation></citation-alternatives></ref></ref-list><fn-group><fn fn-type="conflict"><p>The authors declare that there are no conflicts of interest present.</p></fn></fn-group></back></article>
