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<article article-type="research-article" dtd-version="1.3" xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink" xmlns:xsi="http://www.w3.org/2001/XMLSchema-instance" xml:lang="ru"><front><journal-meta><journal-id journal-id-type="publisher-id">cardiovascular</journal-id><journal-title-group><journal-title xml:lang="ru">Кардиоваскулярная терапия и профилактика</journal-title><trans-title-group xml:lang="en"><trans-title>Cardiovascular Therapy and Prevention</trans-title></trans-title-group></journal-title-group><issn pub-type="ppub">1728-8800</issn><issn pub-type="epub">2619-0125</issn><publisher><publisher-name>«SILICEA-POLIGRAF» LLC</publisher-name></publisher></journal-meta><article-meta><article-id pub-id-type="doi">10.15829/1728-8800-2023-3513</article-id><article-id custom-type="elpub" pub-id-type="custom">cardiovascular-3513</article-id><article-categories><subj-group subj-group-type="heading"><subject>Research Article</subject></subj-group><subj-group subj-group-type="section-heading" xml:lang="ru"><subject>АРТЕРИАЛЬНАЯ ГИПЕРТОНИЯ</subject></subj-group><subj-group subj-group-type="section-heading" xml:lang="en"><subject>ARTERIAL HYPERTENSION</subject></subj-group></article-categories><title-group><article-title>Эпикардиальное ожирение  и механическая дисперсия левого  предсердия  у больных  артериальной гипертензией с пароксизмальной и персистирующей фибрилляцией предсердий</article-title><trans-title-group xml:lang="en"><trans-title>Epicardial obesity and left atrial mechanical dispersion in hypertensive patients with paroxysmal and persistent atrial fibrillation</trans-title></trans-title-group></title-group><contrib-group><contrib contrib-type="author" corresp="yes"><contrib-id contrib-id-type="orcid">https://orcid.org/0000-0002-8879-3791</contrib-id><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Мазур</surname><given-names>Е. С.</given-names></name><name name-style="western" xml:lang="en"><surname>Mazur</surname><given-names>E. S.</given-names></name></name-alternatives><bio xml:lang="ru"><p>Доктор медицинских наук, профессор, заведующий кафедрой госпитальной терапии и профессиональных болезней.</p><p>Тверь</p></bio><bio xml:lang="en"><p>MD, Professor, Head of Chair of Hospital Therapy and Occupational Diseases.</p><p>Tver</p></bio><email xlink:type="simple">mazur-tver@mail.ru</email><xref ref-type="aff" rid="aff-1"/></contrib><contrib contrib-type="author" corresp="yes"><contrib-id contrib-id-type="orcid">https://orcid.org/0000-0003-4818-434X</contrib-id><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Мазур</surname><given-names>В. В.</given-names></name><name name-style="western" xml:lang="en"><surname>Mazur</surname><given-names>V. V.</given-names></name></name-alternatives><bio xml:lang="ru"><p>Мазур Вера В. — доктор медицинских наук, доцент, профессор  кафедры госпитальной терапии и профессиональных болезней.</p><p>Тверь</p></bio><bio xml:lang="en"><p>MD, Chair of Hospital Therapy and Occupational Diseases.</p><p>Tver</p></bio><email xlink:type="simple">vera.v.mazur@gmail.com</email><xref ref-type="aff" rid="aff-1"/></contrib><contrib contrib-type="author" corresp="yes"><contrib-id contrib-id-type="orcid">https://orcid.org/0000-0003-0511-7366</contrib-id><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Баженов</surname><given-names>Н. Д.</given-names></name><name name-style="western" xml:lang="en"><surname>Bazhenov</surname><given-names>N. D.</given-names></name></name-alternatives><bio xml:lang="ru"><p>Кандидат медицинских наук, доцент, заведующий кафедрой скорой медицинской помощи.</p><p>Тверь</p></bio><bio xml:lang="en"><p>PhD, Head of Chair of Emergency Medical Care.</p><p>Tver</p></bio><email xlink:type="simple">bazhenovnd@mail.ru</email><xref ref-type="aff" rid="aff-1"/></contrib><contrib contrib-type="author" corresp="yes"><contrib-id contrib-id-type="orcid">https://orcid.org/0000-0002-0648-5358</contrib-id><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Нилова</surname><given-names>О. В.</given-names></name><name name-style="western" xml:lang="en"><surname>Nilova</surname><given-names>O. V.</given-names></name></name-alternatives><bio xml:lang="ru"><p>Кандидат медицинских наук, доцент кафедры поликлинической терапии и семейной медицины.</p><p>Тверь</p></bio><bio xml:lang="en"><p>PhD, Chair of Ambulatory Therapy and Family Medicine.</p><p>Tver</p></bio><email xlink:type="simple">tevirp69@mail.ru</email><xref ref-type="aff" rid="aff-1"/></contrib><contrib contrib-type="author" corresp="yes"><contrib-id contrib-id-type="orcid">https://orcid.org/0000-0002-1103-5001</contrib-id><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Николаева</surname><given-names>Т. О.</given-names></name><name name-style="western" xml:lang="en"><surname>Nikolaeva</surname><given-names>T. O.</given-names></name></name-alternatives><bio xml:lang="ru"><p>Кандидат медицинских наук, доцент, заведующий кафедрой пропедевтики внутренних болезней.</p><p>Тверь</p></bio><bio xml:lang="en"><p>PhD, Head of Chair of internal diseases.</p><p>Tver</p></bio><email xlink:type="simple">tabo051610@gmail.com</email><xref ref-type="aff" rid="aff-1"/></contrib></contrib-group><aff-alternatives id="aff-1"><aff xml:lang="ru"><institution>Тверской государственным медицинский университет Минздрава России</institution></aff><aff xml:lang="en"><institution>Tver State Medical University</institution></aff></aff-alternatives><pub-date pub-type="collection"><year>2023</year></pub-date><pub-date pub-type="epub"><day>10</day><month>04</month><year>2023</year></pub-date><volume>22</volume><issue>3</issue><fpage>3513</fpage><lpage>3513</lpage><permissions><copyright-statement>Copyright &amp;#x00A9; Мазур Е.С., Мазур В.В., Баженов Н.Д., Нилова О.В., Николаева Т.О., 2023</copyright-statement><copyright-year>2023</copyright-year><copyright-holder xml:lang="ru">Мазур Е.С., Мазур В.В., Баженов Н.Д., Нилова О.В., Николаева Т.О.</copyright-holder><copyright-holder xml:lang="en">Mazur E.S., Mazur V.V., Bazhenov N.D., Nilova O.V., Nikolaeva T.O.</copyright-holder><license xml:lang="ru" license-type="creative-commons-attribution" xlink:href="https://creativecommons.org/licenses/by/4.0/" xlink:type="simple"><license-p>Данная работа распространяется под лицензией Creative Commons Attribution 4.0.</license-p></license><license xml:lang="en" license-type="creative-commons-attribution" xlink:href="https://creativecommons.org/licenses/by/4.0/" xlink:type="simple"><license-p>This work is licensed under a Creative Commons Attribution 4.0 License.</license-p></license></permissions><self-uri xlink:href="https://cardiovascular.elpub.ru/jour/article/view/3513">https://cardiovascular.elpub.ru/jour/article/view/3513</self-uri><abstract><sec><title>Цель</title><p>Цель. Сравнить толщину эпикардиального  ожирения (ЭЖ) в области передней  стенки правого желудочка и механическую дисперсию левого предсердия (МДЛП) у больных артериальной  гипертензией  (АГ) без нарушения сердечного ритма и с различными формами рецидивирующей фибрилляции предсердий  (ФП).</p></sec><sec><title>Материал и методы</title><p>Материал и методы.  В обсервационное одномоментное  одноцентровое исследование включены 383 пациента с АГ, из которых у 251 при целенаправленном обследовании  ФП не выявлена, у 61 отмечалась  пароксизмальная, а у 71 — персистирующая ФП. При эхокардиографическом исследовании,  которое  выполнялось на фоне синусового ритма, измерялась толщина ЭЖ в области передней стенки правого желудочка и с помощью технологии speckle-tracking эхокардиографии  определялась МДЛП, равная процентному отношению стандартного  отклонения времени  достижения пикового значения глобальной продольной деформации миокарда левого предсердия в фазу резервуара к продолжительности сердечного цикла.</p></sec><sec><title>Результаты</title><p>Результаты. У больных АГ без  ФП, с пароксизмальной  и персистирующей ФП толщина ЭЖ равнялась  6,70 [5,80; 8,00], 8,20 [7,10; 9,93] и 8,70 [7,93; 10,0] мм (р&lt;0,0001), МДЛП — 0,72 [0,58; 0,93], 2,87 [2,40; 3,28] и 2,67 [2,11; 3,15]% (р&lt;0,0001), соответственно.</p></sec><sec><title>Заключение</title><p>Заключение.  У  больных АГ с пароксизмальной  и персистирующей ФП толщина ЭЖ в области передней стеки правого желудочка и МДЛП существенно больше, чем у больных без нарушения ритма. У больных с персистирующей ФП толщина жирового слоя больше, чем при пароксизмальной  ФП, в то время как МДЛП при этих формах аритмии практически не различается.</p></sec></abstract><trans-abstract xml:lang="en"><sec><title>Aim</title><p>Aim. To compare  the epicardial fat thickness  (EFT) in right ventricular anterior wall (RVAW) and left atrial mechanical dispersion  (LAMD) in hypertensive (HTN) patients without arrhythmias and with various types of recurrent atrial fibrillation (AF).</p></sec><sec><title>Material and methods</title><p>Material and methods. This observational  cross-sectional single-center  study included 383 patients  with HTN, of which 251 did not have AF,  61 patients  had paroxysmal,  and 71 patients  — persistent AF. Echocardiography  performed  against  the  background  of sinus rhythm assessed the EFT in RVAW. In addition, using speckle-tracking echocardiography, the LAMD was determined,  equal to the percentage of the standard  deviation of the time to peak  global longitudinal LA strain in the reservoir phase to duration of cardiac cycle.</p></sec><sec><title>Results</title><p>Results. In HTN patients without AF, with paroxysmal and persistent AF, the EFT was 6,70 [5,80; 8,00], 8,20 [7,10; 9,93] and 8,70 [7,93; 10,0] mm (р&lt;0,0001), LAMD — 0,72 [0,58; 0,93], 2,87 [2,40; 3,28] and 2,67 [2,11; 3,15]% (p&lt;0,0001), respectively.</p></sec><sec><title>Conclusion</title><p>Conclusion. In HTN patients with paroxysmal and persistent  AF, the EFT in RVAW and LAMD is significantly greater  than in patients without arrhythmias. In patients with persistent  AF, EFT is greater than in paroxysmal AF, while LAMD practically does not differ.</p></sec></trans-abstract><kwd-group xml:lang="ru"><kwd>артериальная  гипертензия</kwd><kwd>фибрилляция предсердий</kwd><kwd>эпикардиальный жир</kwd><kwd>speckle-tracking  эхокардиография</kwd><kwd>механическая дисперсия левого предсердия</kwd></kwd-group><kwd-group xml:lang="en"><kwd>hypertension</kwd><kwd>atrial fibrillation</kwd><kwd>epicardial  fat</kwd><kwd>speckle-tracking echocardiography</kwd><kwd>left atrial mechanical dispersion</kwd></kwd-group></article-meta></front><back><ref-list><title>References</title><ref id="cit1"><label>1</label><citation-alternatives><mixed-citation xml:lang="ru">Podzolkov VI, Tarzimanova AI, Bragina AE, et al. Role of epicardial adipose tissue in the development of atrial fibrillation in hypertensive patients. Cardiovascular Therapy and Prevention. 2020;19(6):2707. 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