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<article article-type="research-article" dtd-version="1.3" xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink" xmlns:xsi="http://www.w3.org/2001/XMLSchema-instance" xml:lang="ru"><front><journal-meta><journal-id journal-id-type="publisher-id">cardiovascular</journal-id><journal-title-group><journal-title xml:lang="ru">Кардиоваскулярная терапия и профилактика</journal-title><trans-title-group xml:lang="en"><trans-title>Cardiovascular Therapy and Prevention</trans-title></trans-title-group></journal-title-group><issn pub-type="ppub">1728-8800</issn><issn pub-type="epub">2619-0125</issn><publisher><publisher-name>«SILICEA-POLIGRAF» LLC</publisher-name></publisher></journal-meta><article-meta><article-id pub-id-type="doi">10.15829/1728-8800-2014-4-69-74</article-id><article-id custom-type="elpub" pub-id-type="custom">cardiovascular-37</article-id><article-categories><subj-group subj-group-type="heading"><subject>Research Article</subject></subj-group><subj-group subj-group-type="section-heading" xml:lang="ru"><subject>ОБЗОРЫ</subject></subj-group><subj-group subj-group-type="section-heading" xml:lang="en"><subject>REVIEWS</subject></subj-group></article-categories><title-group><article-title>СОВРЕМЕННЫЕ ПРИНЦИПЫ АНТИТРОМБОЦИТАРНОЙ ТЕРАПИИ В ЛЕЧЕНИИ БОЛЬНЫХ ИШЕМИЧЕСКОЙ БОЛЕЗНЬЮ СЕРДЦА</article-title><trans-title-group xml:lang="en"><trans-title>CONTEMPORARY APPROACHES TO ANTIPLATELET THERAPY IN CORONARY HEART DISEASE TREATMENT</trans-title></trans-title-group></title-group><contrib-group><contrib contrib-type="author" corresp="yes"><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Мацкеплишвили</surname><given-names>С. Т.</given-names></name><name name-style="western" xml:lang="en"><surname>Matskeplishvili</surname><given-names>S. T.</given-names></name></name-alternatives><bio xml:lang="ru"><p>д.м.н., с.н.с. клинико-диагностического отделения</p></bio><xref ref-type="aff" rid="aff-1"/></contrib><contrib contrib-type="author" corresp="yes"><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Арутюнова</surname><given-names>Я. Э.</given-names></name><name name-style="western" xml:lang="en"><surname>Arutyunova</surname><given-names>S. Ya.</given-names></name></name-alternatives><bio xml:lang="ru"><p>аспирант отделения</p><p>Тел.: (499) 414–77–55 </p></bio><bio xml:lang="en"/><email xlink:type="simple">iko83@mail.ru</email><xref ref-type="aff" rid="aff-1"/></contrib></contrib-group><aff-alternatives id="aff-1"><aff xml:lang="ru"><institution>Научный центр сердечно-сосудистой хирургии им. А.Н. Бакулева РАМН, Москва</institution></aff><aff xml:lang="en"><institution>The Scientific Centre for Cardiovascular surgery n.a. Bakulev A.N. Moscow</institution></aff></aff-alternatives><pub-date pub-type="collection"><year>2014</year></pub-date><pub-date pub-type="epub"><day>20</day><month>08</month><year>2014</year></pub-date><volume>13</volume><issue>4</issue><fpage>69</fpage><lpage>74</lpage><permissions><copyright-statement>Copyright &amp;#x00A9; Мацкеплишвили С.Т., Арутюнова Я.Э., 2014</copyright-statement><copyright-year>2014</copyright-year><copyright-holder xml:lang="ru">Мацкеплишвили С.Т., Арутюнова Я.Э.</copyright-holder><copyright-holder xml:lang="en">Matskeplishvili S.T., Arutyunova S.Y.</copyright-holder><license xml:lang="ru" license-type="creative-commons-attribution" xlink:href="https://creativecommons.org/licenses/by/4.0/" xlink:type="simple"><license-p>Данная работа распространяется под лицензией Creative Commons Attribution 4.0.</license-p></license><license xml:lang="en" license-type="creative-commons-attribution" xlink:href="https://creativecommons.org/licenses/by/4.0/" xlink:type="simple"><license-p>This work is licensed under a Creative Commons Attribution 4.0 License.</license-p></license></permissions><self-uri xlink:href="https://cardiovascular.elpub.ru/jour/article/view/37">https://cardiovascular.elpub.ru/jour/article/view/37</self-uri><abstract><p>Чрескожные коронарные вмешательства (ЧКВ) все шире используются как метод реваскуляризации миокарда при ишемической болезни сердца (ИБС). Двойная антитромбоцитарная терапия, включая ацетилсалициловую кислоту и клопидогрел, вошла в рутинную практику лечения пациентов с ИБС, направляемых на ЧКВ для предотвращения развития тромбоза. Максимальная оптимизация двойной антитромбоцитарной терапии с оценкой степени агрегации тромбоцитов после проведенного ЧКВ может иметь дополнительное влияние на кардиоваскулярную заболеваемость и смертность. </p></abstract><trans-abstract xml:lang="en"><p>Transcutaneous interventions (PCI) are in growing usage as a method to revascularize myocardium in coronary heart disease. Double antiplatelet therapy, including acetylsalicylic acid clopidogrel, is now routinely prescribed for CHD patients preparing to undergo coronary intervention to prevent thrombosis. Reaching the maximum advantage in double antiplatelet therapy with control of platelet function after PCI may have additional value in cardiovascular morbidity and mortality prevention. </p></trans-abstract><kwd-group xml:lang="ru"><kwd>ишемическая болезнь сердца</kwd><kwd>двойная антитромбоцитарная терапия</kwd><kwd>тромбоз</kwd></kwd-group><kwd-group xml:lang="en"><kwd>ischemic heart disease</kwd><kwd>dual antiplatelet therapy</kwd><kwd>thrombosis</kwd></kwd-group></article-meta></front><back><ref-list><title>References</title><ref id="cit1"><label>1</label><citation-alternatives><mixed-citation xml:lang="ru">The World Health Report 2001. Geneva: WHO; 2001.</mixed-citation><mixed-citation xml:lang="en">The World Health Report 2001. Geneva: WHO; 2001.</mixed-citation></citation-alternatives></ref><ref id="cit2"><label>2</label><citation-alternatives><mixed-citation xml:lang="ru">Panchenko EP. The concept is the basis of the pathogenesis of atherothrombotic cardiovascular disease. 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