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<article article-type="research-article" dtd-version="1.3" xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink" xmlns:xsi="http://www.w3.org/2001/XMLSchema-instance" xml:lang="ru"><front><journal-meta><journal-id journal-id-type="publisher-id">cardiovascular</journal-id><journal-title-group><journal-title xml:lang="ru">Кардиоваскулярная терапия и профилактика</journal-title><trans-title-group xml:lang="en"><trans-title>Cardiovascular Therapy and Prevention</trans-title></trans-title-group></journal-title-group><issn pub-type="ppub">1728-8800</issn><issn pub-type="epub">2619-0125</issn><publisher><publisher-name>«SILICEA-POLIGRAF» LLC</publisher-name></publisher></journal-meta><article-meta><article-id pub-id-type="doi">10.15829/1728-8800-2024-4097</article-id><article-id custom-type="edn" pub-id-type="custom">XUQLBF</article-id><article-id custom-type="elpub" pub-id-type="custom">cardiovascular-4097</article-id><article-categories><subj-group subj-group-type="heading"><subject>Research Article</subject></subj-group><subj-group subj-group-type="section-heading" xml:lang="ru"><subject>АРТЕРИАЛЬНАЯ ГИПЕРТОНИЯ</subject></subj-group><subj-group subj-group-type="section-heading" xml:lang="en"><subject>ARTERIAL HYPERTENSION</subject></subj-group></article-categories><title-group><article-title>Распространенность артериальной гипертензии среди мужского населения 35-74 лет г. Новосибирска</article-title><trans-title-group xml:lang="en"><trans-title>Hypertension prevalence among the male population aged 35-74 years in Novosibirsk</trans-title></trans-title-group></title-group><contrib-group><contrib contrib-type="author" corresp="yes"><contrib-id contrib-id-type="orcid">https://orcid.org/0009-0001-0081-1503</contrib-id><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Исмаилова</surname><given-names>М. А.</given-names></name><name name-style="western" xml:lang="en"><surname>Ismailova</surname><given-names>M. A.</given-names></name></name-alternatives><bio xml:lang="ru"><p>Мария Андреевна Исмаилова — м.н.с. лаборатории генетических и средовых детерминант жизненного цикла человека.</p><p>Новосибирск</p></bio><bio xml:lang="en"><p>Maria A. Ismailova - Junior Researcher at the Laboratory of Genetic and Environmental Determinants of the Human Life Cycle, IIPM — branch of ICG SB RAS.</p><p>Novosibirsk</p></bio><email xlink:type="simple">mary1998lac@gmail.com</email><xref ref-type="aff" rid="aff-1"/></contrib><contrib contrib-type="author" corresp="yes"><contrib-id contrib-id-type="orcid">https://orcid.org/0000-0001-7875-1566</contrib-id><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Афанасьева</surname><given-names>А. Д.</given-names></name><name name-style="western" xml:lang="en"><surname>Afanaseva</surname><given-names>A. D.</given-names></name></name-alternatives><bio xml:lang="ru"><p>Алена Дмитриевна Афанасьева — к.м.н., зав. лабораторией генетических и средовых детерминант жизненного цикла человека.</p><p>Новосибирск</p></bio><bio xml:lang="en"><p>Alena D. Afanaseva - Candidate of Medical Sciences, Head of the Laboratory of Genetic and Environmental Determinants of the Human Life Cycle, IIPM — branch of ICG SB RAS.</p><p>Novosibirsk</p></bio><email xlink:type="simple">alene.elene@gmail.com</email><xref ref-type="aff" rid="aff-1"/></contrib><contrib contrib-type="author" corresp="yes"><contrib-id contrib-id-type="orcid">https://orcid.org/0000-0001-5316-4664</contrib-id><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Гарбузова</surname><given-names>Е. В.</given-names></name><name name-style="western" xml:lang="en"><surname>Garbuzova</surname><given-names>E. V.</given-names></name></name-alternatives><bio xml:lang="ru"><p>Евгения Витальевна Гарбузова — к.м.н., н.с. лаборатории генетических и средовых детерминант жизненного цикла человека.</p><p>Новосибирск</p></bio><bio xml:lang="en"><p>Evgeniia V. Garbuzova - Candidate of Medical Sciences, Researcher at the Laboratory of Genetic and Environmental Determinants of the Human Life Cycle, IIPM — branch of ICG SB RAS.</p><p>Novosibirsk</p></bio><email xlink:type="simple">stryukova.j@mail.ru</email><xref ref-type="aff" rid="aff-1"/></contrib><contrib contrib-type="author" corresp="yes"><contrib-id contrib-id-type="orcid">https://orcid.org/0000-0002-0436-2549</contrib-id><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Шрамко</surname><given-names>В. С.</given-names></name><name name-style="western" xml:lang="en"><surname>Shramko</surname><given-names>V. S.</given-names></name></name-alternatives><bio xml:lang="ru"><p>Виктория Сергеевна Шрамко — к.м.н., н.с. лаборатории клинических биохимических и гормональных исследований терапевтических заболеваний.</p><p>Новосибирск</p></bio><bio xml:lang="en"><p>Victoria S. Shramko - Candidate of Medical Sciences, Researcher at the Laboratory of Clinical Biochemical and Hormonal Studies of Therapeutic Diseases, IIPM — branch of ICG SB RAS.</p><p>Novosibirsk</p></bio><email xlink:type="simple">nosova@211.ru</email><xref ref-type="aff" rid="aff-1"/></contrib><contrib contrib-type="author" corresp="yes"><contrib-id contrib-id-type="orcid">https://orcid.org/0000-0002-4030-6130</contrib-id><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Симонова</surname><given-names>Г. И.</given-names></name><name name-style="western" xml:lang="en"><surname>Simonova</surname><given-names>G. I.</given-names></name></name-alternatives><bio xml:lang="ru"><p>Галина Ильинична Симонова — д.м.н., профессор, г.н.с. лаборатории этиопатогенеза и клиники внутренних заболеваний.</p><p>Новосибирск</p></bio><bio xml:lang="en"><p>Galina I. Simonova - Doctor of Medical Sciences, Professor, Chief Researcher of the Laboratory of Etiopathogenesis and the Clinic of Internal Diseases, IIPM — branch of ICG SB RAS.</p><p>Novosibirsk</p></bio><email xlink:type="simple">g.simonova2019@gmail.com</email><xref ref-type="aff" rid="aff-1"/></contrib><contrib contrib-type="author" corresp="yes"><contrib-id contrib-id-type="orcid">https://orcid.org/0000-0003-2605-7163</contrib-id><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Герасименко</surname><given-names>О. Н.</given-names></name><name name-style="western" xml:lang="en"><surname>Gerasimenko</surname><given-names>O. N.</given-names></name></name-alternatives><bio xml:lang="ru"><p>Оксана Николаевна Герасименко — д.м.н., профессор, зав. кафедрой факультетской терапии им. проф. Г. Д. Залесского.</p><p>Новосибирск</p></bio><bio xml:lang="en"><p>Oksana N. Gerasimenko - Doctor of Medical Sciences, Professor, Head of the department of faculty therapy named after prof. G.D. Zalessky, Novosibirsk State Medical University</p><p>Novosibirsk</p></bio><email xlink:type="simple">profgerasimenko@inbox.ru</email><xref ref-type="aff" rid="aff-2"/></contrib><contrib contrib-type="author" corresp="yes"><contrib-id contrib-id-type="orcid">https://orcid.org/0000-0003-0871-7551</contrib-id><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Шпагина</surname><given-names>Л. А.</given-names></name><name name-style="western" xml:lang="en"><surname>Shpagina</surname><given-names>L. N.</given-names></name></name-alternatives><bio xml:lang="ru"><p>Любовь Анатольевна Шпагина — д.м.н., профессор, зав. кафедрой госпитальной терапии и медицинской реабилитации.</p><p>Новосибирск</p></bio><bio xml:lang="en"><p>Lyubov N. Shpagina - Doctor of Medical Sciences, Professor, Head of the internal medicine and rehabilitation department, Novosibirsk State Medical University.</p><p>Novosibirsk</p></bio><email xlink:type="simple">lashpagina@gmail.com</email><xref ref-type="aff" rid="aff-2"/></contrib><contrib contrib-type="author" corresp="yes"><contrib-id contrib-id-type="orcid">https://orcid.org/0000-0002-9332-0622</contrib-id><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Имаева</surname><given-names>А. Э.</given-names></name><name name-style="western" xml:lang="en"><surname>Imaeva</surname><given-names>A. E.</given-names></name></name-alternatives><bio xml:lang="ru"><p>Асия Эмвяровна Имаева — д.м.н., в.н.с. отдела эпидемиологии хронических неинфекционных заболеваний.</p><p>Москва</p></bio><bio xml:lang="en"><p>Asiia E. Imaeva - Doctor of Medical Sciences, Leading Researcher, Department of Epidemiology of Chronic Non-communicable Diseases, National Medical Research Centre for Therapy and Preventive Medicine.</p><p>Moscow</p></bio><email xlink:type="simple">imaevaasiia@yandex.ru</email><xref ref-type="aff" rid="aff-3"/></contrib><contrib contrib-type="author" corresp="yes"><contrib-id contrib-id-type="orcid">https://orcid.org/0000-0001-8011-2798</contrib-id><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Баланова</surname><given-names>Ю. А.</given-names></name><name name-style="western" xml:lang="en"><surname>Balanova</surname><given-names>Yu. A.</given-names></name></name-alternatives><bio xml:lang="ru"><p>Юлия Андреевна Баланова — д.м.н., в.н.с. отдела эпидемиологии хронических неинфекционных заболеваний.</p><p>Москва</p></bio><bio xml:lang="en"><p>Yulia A. Balanova - Doctor of Medical Sciences, Leading Researcher, Department of Epidemiology of Chronic Non-communicable Diseases, National Medical Research Centre for Therapy and Preventive Medicine.</p><p>Moscow</p></bio><email xlink:type="simple">JBalanova@gnicpm.ru</email><xref ref-type="aff" rid="aff-3"/></contrib><contrib contrib-type="author" corresp="yes"><contrib-id contrib-id-type="orcid">https://orcid.org/0000-0002-4936-8362</contrib-id><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Рагино</surname><given-names>Ю. И.</given-names></name><name name-style="western" xml:lang="en"><surname>Ragino</surname><given-names>Yu. I.</given-names></name></name-alternatives><bio xml:lang="ru"><p>Юлия Игоревна Рагино — д.м.н., профессор, член-корр. РАН, руководитель.</p><p>Новосибирск</p></bio><bio xml:lang="en"><p>Yulia I. Ragino - Doctor of Medical Sciences, Professor, Corresponding Member of the Russian Academy of Sciences, Head of Internal Diseases of the IIPM — branch of ICG SB RAS.</p><p>Novosibirsk</p></bio><email xlink:type="simple">ragino@mail.ru</email><xref ref-type="aff" rid="aff-1"/></contrib></contrib-group><aff-alternatives id="aff-1"><aff xml:lang="ru"><institution>Научно-исследовательский институт терапии и профилактической медицины — филиал ФГБНУ "Федеральный исследовательский центр Институт цитологии и генетики Сибирского отделения Российской академии наук"</institution></aff><aff xml:lang="en"><institution>Research Institute for Internal and Preventive Medicine — branch of the Federal Research Center Institute of Cytology and Genetics</institution></aff></aff-alternatives><aff-alternatives id="aff-2"><aff xml:lang="ru"><institution>ФГБОУ ВО "Новосибирский государственный медицинский университет" Минздрава России</institution></aff><aff xml:lang="en"><institution>Novosibirsk State Medical University</institution></aff></aff-alternatives><aff-alternatives id="aff-3"><aff xml:lang="ru"><institution>ФГБУ "Национальный медицинский исследовательский центр терапии и профилактической медицины" Минздрава России</institution></aff><aff xml:lang="en"><institution>National Medical Research Centre for Therapy and Preventive Medicine</institution></aff></aff-alternatives><pub-date pub-type="collection"><year>2024</year></pub-date><pub-date pub-type="epub"><day>22</day><month>10</month><year>2024</year></pub-date><volume>23</volume><issue>9</issue><fpage>4097</fpage><lpage>4097</lpage><permissions><copyright-statement>Copyright &amp;#x00A9; Исмаилова М.А., Афанасьева А.Д., Гарбузова Е.В., Шрамко В.С., Симонова Г.И., Герасименко О.Н., Шпагина Л.А., Имаева А.Э., Баланова Ю.А., Рагино Ю.И., 2024</copyright-statement><copyright-year>2024</copyright-year><copyright-holder xml:lang="ru">Исмаилова М.А., Афанасьева А.Д., Гарбузова Е.В., Шрамко В.С., Симонова Г.И., Герасименко О.Н., Шпагина Л.А., Имаева А.Э., Баланова Ю.А., Рагино Ю.И.</copyright-holder><copyright-holder xml:lang="en">Ismailova M.A., Afanaseva A.D., Garbuzova E.V., Shramko V.S., Simonova G.I., Gerasimenko O.N., Shpagina L.N., Imaeva A.E., Balanova Y.A., Ragino Y.I.</copyright-holder><license xml:lang="ru" license-type="creative-commons-attribution" xlink:href="https://creativecommons.org/licenses/by/4.0/" xlink:type="simple"><license-p>Данная работа распространяется под лицензией Creative Commons Attribution 4.0.</license-p></license><license xml:lang="en" license-type="creative-commons-attribution" xlink:href="https://creativecommons.org/licenses/by/4.0/" xlink:type="simple"><license-p>This work is licensed under a Creative Commons Attribution 4.0 License.</license-p></license></permissions><self-uri xlink:href="https://cardiovascular.elpub.ru/jour/article/view/4097">https://cardiovascular.elpub.ru/jour/article/view/4097</self-uri><abstract><sec><title>Цель</title><p>Цель. Изучение распространенности артериальной гипертензии (АГ), ее факторов риска, охвата лечением, его структуры, эффективности, а также показателей контроля заболевания среди мужского населения 35-74 лет г. Новосибирска.</p></sec><sec><title>Материал и методы</title><p>Материал и методы. На базе НИИТПМ — филиал ИЦиГ СО РАН в 2021-2023гг проведено одномоментное популяционное исследование населения г. Новосибирска по протоколу исследования "Эпидемиология сердечно-сосудистых заболеваний и факторов их риска в Российской Федерации. Третье исследование" (­ЭССЕ-РФ3). Всего обследовано 1200 человек в возрасте 35-74 года, проживающих в г. Новосибирске. В анализ включены 600 мужчин. Отклик превысил 70%. АГ считалась выявленной, если при измерении систолическое артериальное давление (АД) &gt;140 мм рт.ст. и/или диастолическое АД &gt;90 мм рт.ст. и/или имеется факт приема антигипертензивных препаратов (АГП). Осведомленность рассчитывалась как доля лиц, которым ранее врач сообщал о наличии у них АГ. Эффективность лечения понимается как доля лиц, достигших целевых показателей АД на фоне приема АГП. Контроль АГ — доля лиц, достигших целевых значений, среди всех обследованных с АГ. Статистическая обработка полученных результатов проводилась с использованием программного пакета SPSS (версия 13.0). Ассоциации оценивались с помощью множественного логистического регрессионного анализа. Критический уровень значимости нулевой гипотезы (p) был принят равным 0,05.</p></sec><sec><title>Результаты</title><p>Результаты. Медианы систолического и диастолического АД среди мужчин г. Новосибирска составили 136,0 [126,5; 149,5] и 89,0 [82,0; 95,5] мм рт.ст., соответственно. Распространенность АГ среди мужчин 35-74 лет г. Новосибирска составила 68,9%. О наличии АГ в г. Новосибирске осведомлены 81,1% мужчин. Среди мужчин с АГ АГП принимают 54,7%. Эффективность лечения среди мужчин г. Новосибирска составляет 32,3%, контролируют заболевание 19,6% мужчин. Шанс наличия АГ у мужчин при наличии гипертриглицеридемии повышался в 3,5 раза, при абдоминальном ожирении — в 2 раза, при отягощенной наследственности — в 1,6 раз, и с каждым годом жизни увеличивался в 1,1 раза.</p></sec><sec><title>Заключение</title><p>Заключение. Распространенность АГ среди мужчин в г. Новоси­бирске выше в сравнении со среднероссийским уровнем. Зна­чи­мыми оказались такие факторы риска АГ, как абдоминальное ожирение, гипертриглицеридемия, сниженная физическая активность. В то время как осведомленность, охват лечением и контроль АГ среди мужчин 35-74 лет г. Новосибирска соответствуют российским тенденциям, такой показатель, как эффективность лечения оказался несколько ниже, чем в российской популяции.</p></sec></abstract><trans-abstract xml:lang="en"><sec><title>Aim</title><p>Aim. To study the prevalence and risk factors of hypertension (HTN), structure and effectiveness of treatment coverage, as well as disease control indicators among the male population aged 35-74 years in Novosibirsk.</p></sec><sec><title>Material and methods</title><p>Material and methods. This cross-sectional study of the Novosibirsk population was conducted in 2021-2023 at the Research Institute for Internal and Preventive Medicine — branch of the Federal Research Center Institute of Cytology and Genetics according to the ESSE-RF3 study protocol. A total of 1200 people aged 35-74 years living in Novosibirsk were examined. The analysis included 600 men. The response rate exceeded 70%. HTN was considered detected in systolic blood pressure (BP) ≥140 mm Hg and/or diastolic BP ≥90 mm Hg and/or in patients taking antihypertensive agents. Awareness was estimated as the proportion of individuals who had previously been informed by a physician about HTN. Treatment effectiveness was considered the proportion of individuals who achieved target BP values while taking antihypertensive therapy. Hypertension control was considered the proportion of individuals who achieved target values among all those examined with HTN. Statistical processing was performed using the SPSS software package (version 13.0). Associations were assessed using multiple logistic regression analysis. The critical significance level of the null hypothesis (p) was 0,05.</p></sec><sec><title>Results</title><p>Results. The medians of systolic and diastolic BP among men in No­vo­sibirsk were 136,0 [126,5; 149,5] and 89,0 [82,0; 95,5] mm Hg, respectively. The prevalence of HTN among men aged 35-74 in Novo­sibirsk was 68,9%, while 81,1% of men in Novosibirsk were aware of HTN. Among men with HTN, 54,7% take antihypertensive agents. The effectiveness of treatment among men in Novosibirsk is 32,3%, while 19,6% of men control the disease. The odds of hypertension occurrence in men with hypertriglyceridemia increased by 3,5 times, with abdominal obesity — by 2 times, with an positive family history for cardiovascular diseases — by 1,6 times, and with each year of life increased by 1,1 times.</p></sec><sec><title>Conclusion</title><p>Conclusion. The prevalence of HTN among men in Novosibirsk is higher in comparison with the average Russian level. Significant risk factors for HTN include abdominal obesity, hypertriglyceridemia, and decreased physical activity. While awareness, treatment coverage, and HTN control among men aged 35-74 in Novosibirsk correspond to Russian trends, treatment effectiveness turned out to be slightly lower than in the Russian population.</p></sec></trans-abstract><kwd-group xml:lang="ru"><kwd>артериальная гипертензия</kwd><kwd>осведомленность</kwd><kwd>охват лечением</kwd><kwd>эффективность лечения</kwd><kwd>контроль</kwd><kwd>систолическое артериальное давление</kwd><kwd>диастолическое артериальное давление</kwd></kwd-group><kwd-group xml:lang="en"><kwd>hypertension</kwd><kwd>awareness</kwd><kwd>treatment coverage</kwd><kwd>treatment effectiveness</kwd><kwd>control</kwd><kwd>systolic blood pressure</kwd><kwd>diastolic blood pressure</kwd></kwd-group><funding-group><funding-statement xml:lang="ru">Работа выполнена в рамках исследования ЭССЕ-РФ3 и государственного задания "Формирование когорт детского, подросткового, молодого населения для изучения механизмов и особенностей жизненного цикла человека в российской популяции". Гос. рег. № 122031700115-7</funding-statement><funding-statement xml:lang="en">The work was carried out within the ESSE-RF3 study and the state assignment "Formation of cohorts of children, adolescents, young people to study the mechanisms and characteristics of the human life cycle in the Russian population". State registration № 122031700115-7</funding-statement></funding-group></article-meta></front><back><ref-list><title>References</title><ref id="cit1"><label>1</label><citation-alternatives><mixed-citation xml:lang="ru">GBD 2017 Risk Factor Collaborators. Global, regional, and na­tional comparative risk assessment of 84 behavioural, environmental and occupational, and metabolic risks or clusters of risks for 195 countries and territories, 1990-2017: a systematic analysis for the Global Burden of Disease Study 2017. Lancet. 2018;392(10159):1923-94. doi:10.1016/S0140-6736(18)32225-6.</mixed-citation><mixed-citation xml:lang="en">GBD 2017 Risk Factor Collaborators. 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