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<article article-type="research-article" dtd-version="1.3" xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink" xmlns:xsi="http://www.w3.org/2001/XMLSchema-instance" xml:lang="ru"><front><journal-meta><journal-id journal-id-type="publisher-id">cardiovascular</journal-id><journal-title-group><journal-title xml:lang="ru">Кардиоваскулярная терапия и профилактика</journal-title><trans-title-group xml:lang="en"><trans-title>Cardiovascular Therapy and Prevention</trans-title></trans-title-group></journal-title-group><issn pub-type="ppub">1728-8800</issn><issn pub-type="epub">2619-0125</issn><publisher><publisher-name>«SILICEA-POLIGRAF» LLC</publisher-name></publisher></journal-meta><article-meta><article-id pub-id-type="doi">10.15829/1728-8800-2024-4234</article-id><article-id custom-type="edn" pub-id-type="custom">CGBTUK</article-id><article-id custom-type="elpub" pub-id-type="custom">cardiovascular-4234</article-id><article-categories><subj-group subj-group-type="heading"><subject>Research Article</subject></subj-group><subj-group subj-group-type="section-heading" xml:lang="ru"><subject>СОВЕТ ЭКСПЕРТОВ</subject></subj-group><subj-group subj-group-type="section-heading" xml:lang="en"><subject>EXPERT CONSENSUS</subject></subj-group></article-categories><title-group><article-title>Заседание Совета по терапевтическим наукам Отделения медицинских наук РАН: Марафон научных проектов терапевтических кафедр России "От инновационных технологий и образования к практике здравоохранения. Кишечная микробиота: различные клинические аспекты"</article-title><trans-title-group xml:lang="en"><trans-title>The Department of Medical Sciences of the RAS, Therapeutic Sciences Council meeting: Scientific projects marathon of Russian therapeutic departments "From innovative technologies and education to healthcare practice. Gut microbiota: clinical aspects"</trans-title></trans-title-group></title-group><contrib-group><contrib contrib-type="author" corresp="yes"><contrib-id contrib-id-type="orcid">https://orcid.org/0000-0002-4453-8430</contrib-id><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Драпкина</surname><given-names>О. М.</given-names></name><name name-style="western" xml:lang="en"><surname>Drapkina</surname><given-names>O. M.</given-names></name></name-alternatives><bio xml:lang="ru"><p>Академик РАН, д.м.н., профессор, директор.</p><p>Москва</p></bio><bio xml:lang="en"><p>Moscow</p></bio><email xlink:type="simple">drapkina@bk.ru</email><xref ref-type="aff" rid="aff-1"/></contrib><contrib contrib-type="author" corresp="yes"><contrib-id contrib-id-type="orcid">https://orcid.org/0000-0002-3297-1608</contrib-id><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Бакиров</surname><given-names>Б. А.</given-names></name><name name-style="western" xml:lang="en"><surname>Bakirov</surname><given-names>B. A.</given-names></name></name-alternatives><bio xml:lang="ru"><p>д.м.н., доцент, зав. кафедрой госпитальной терапии № 2.</p><p>Уфа</p></bio><bio xml:lang="en"><p>Ufa</p></bio><email xlink:type="simple">bakirovb@gmail.com</email><xref ref-type="aff" rid="aff-2"/></contrib><contrib contrib-type="author" corresp="yes"><contrib-id contrib-id-type="orcid">https://orcid.org/0009-0008-4371-1597</contrib-id><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Бакирова</surname><given-names>А. Э.</given-names></name><name name-style="western" xml:lang="en"><surname>Bakirova</surname><given-names>A. E.</given-names></name></name-alternatives><bio xml:lang="ru"><p>Ассистент кафедры госпитальной терапии № 2.</p><p>Уфа</p></bio><bio xml:lang="en"><p>Ufa</p></bio><email xlink:type="simple">bakirovanna@gmail.com</email><xref ref-type="aff" rid="aff-3"/></contrib><contrib contrib-type="author" corresp="yes"><contrib-id contrib-id-type="orcid">https://orcid.org/0000-0003-3791-4052</contrib-id><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Кляритская</surname><given-names>И. Л.</given-names></name><name name-style="western" xml:lang="en"><surname>Klyaritskaya</surname><given-names>I. L.</given-names></name></name-alternatives><bio xml:lang="ru"><p>д.м.н., профессор, зав. кафедрой терапии, гастроэнтерологии, кардиологии, ОВП (семейной медицины).</p><p>Симферополь</p></bio><bio xml:lang="en"><p>Simferopol</p></bio><email xlink:type="simple">klira3@yandex.ru</email><xref ref-type="aff" rid="aff-4"/></contrib><contrib contrib-type="author" corresp="yes"><contrib-id contrib-id-type="orcid">https://orcid.org/0000-0002-8176-4744</contrib-id><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Максимова</surname><given-names>Е. В.</given-names></name><name name-style="western" xml:lang="en"><surname>Maksimova</surname><given-names>E. V.</given-names></name></name-alternatives><bio xml:lang="ru"><p>к.м.н., доцент кафедры терапии, гастроэнтерологии, кардиологии, общей врачебной практики (семейной медицины).</p><p>Симферополь</p></bio><bio xml:lang="en"><p>Simferopol</p></bio><email xlink:type="simple">HelenMaksimovatt@mail.ru</email><xref ref-type="aff" rid="aff-4"/></contrib><contrib contrib-type="author" corresp="yes"><contrib-id contrib-id-type="orcid">https://orcid.org/0000-0002-0656-7097</contrib-id><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Склянная</surname><given-names>Е. В.</given-names></name><name name-style="western" xml:lang="en"><surname>Sklyannaya</surname><given-names>E. V.</given-names></name></name-alternatives><bio xml:lang="ru"><p>к.м.н., доцент кафедры внутренних болезней № 3; зав. отделом гематологии.</p><p>Донецк</p></bio><bio xml:lang="en"><p>Donetsk</p></bio><email xlink:type="simple">elena_skl1979@mail.ru</email><xref ref-type="aff" rid="aff-5"/></contrib><contrib contrib-type="author" corresp="yes"><contrib-id contrib-id-type="orcid">https://orcid.org/0000-0003-4307-1522</contrib-id><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Ватутин</surname><given-names>Н. Т.</given-names></name><name name-style="western" xml:lang="en"><surname>Vatutin</surname><given-names>N. T.</given-names></name></name-alternatives><bio xml:lang="ru"><p>д.м.н., профессор, зав. кафедрой внутренних болезней № 3; зав. отделом кардиологии Минздрава России.</p><p>Донецк</p></bio><bio xml:lang="en"><p>Donetsk</p></bio><email xlink:type="simple">kafedra_vatutin@mail.ru</email><xref ref-type="aff" rid="aff-5"/></contrib><contrib contrib-type="author" corresp="yes"><contrib-id contrib-id-type="orcid">https://orcid.org/0009-0002-3184-7573</contrib-id><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Гарбузова</surname><given-names>Е. В.</given-names></name><name name-style="western" xml:lang="en"><surname>Garbuzova</surname><given-names>E. V.</given-names></name></name-alternatives><bio xml:lang="ru"><p>Лаборатория клиномики, лаборант-исследователь.</p><p>Москва</p></bio><bio xml:lang="en"><p>Moscow</p></bio><email xlink:type="simple">vostryakova.elizaveta@yandex.ru</email><xref ref-type="aff" rid="aff-1"/></contrib><contrib contrib-type="author" corresp="yes"><contrib-id contrib-id-type="orcid">https://orcid.org/0000-0002-6581-7017</contrib-id><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Ливзан</surname><given-names>М. А.</given-names></name><name name-style="western" xml:lang="en"><surname>Livzan</surname><given-names>M. A.</given-names></name></name-alternatives><bio xml:lang="ru"><p>Член-корр. РАН, д.м.н., профессор, ректор, зав. кафедрой факультетской терапии и гастроэнтерологии.</p><p>Омск</p></bio><bio xml:lang="en"><p>Omsk</p></bio><email xlink:type="simple">mlivzan@yandex.ru</email><xref ref-type="aff" rid="aff-6"/></contrib><contrib contrib-type="author" corresp="yes"><contrib-id contrib-id-type="orcid">https://orcid.org/0000-0001-7989-0760</contrib-id><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Ершова</surname><given-names>А. И.</given-names></name><name name-style="western" xml:lang="en"><surname>Ershova</surname><given-names>A. I.</given-names></name></name-alternatives><bio xml:lang="ru"><p>д.м.н., лаборатория клиномики, руководитель, зам. директора по фундаментальной науке.</p><p>Москва</p></bio><bio xml:lang="en"><p>Moscow</p></bio><email xlink:type="simple">alersh@mail.ru</email><xref ref-type="aff" rid="aff-1"/></contrib></contrib-group><aff-alternatives id="aff-1"><aff xml:lang="ru"><institution>ФГБУ "Национальный медицинский исследовательский центр терапии и профилактической медицины" Минздрава России</institution></aff><aff xml:lang="en"><institution>National Medical Research Center for Therapy and Preventive Medicine</institution></aff></aff-alternatives><aff-alternatives id="aff-2"><aff xml:lang="ru"><institution>ФГБОУ ВО "Башкирский государственный медицинский университет" Минздрава России</institution></aff><aff xml:lang="en"><institution>Bashkir State Medical University</institution></aff></aff-alternatives><aff-alternatives id="aff-3"><aff xml:lang="ru"><institution>ФГБОУ ВО «Башкирский государственный медицинский университет» Минздрава России</institution></aff><aff xml:lang="en"><institution>Bashkir State Medical University</institution></aff></aff-alternatives><aff-alternatives id="aff-4"><aff xml:lang="ru"><institution>ФГАОУ ВО "Крымский федеральный университет им. В.И. Вернадского", Ордена Трудового Красного Знамени Медицинский институт им. С.И. Георгиевского</institution></aff><aff xml:lang="en"><institution>Vernadsky Crimean Federal University, S.I. Georgievsky Medical institute</institution></aff></aff-alternatives><aff-alternatives id="aff-5"><aff xml:lang="ru"><institution>ФГБОУ ВО "Донецкий государственный медицинский университет им. М. Горького" Минздрава России; ФГБУ "Институт неотложной и восстановительной хирургии им. В.К. Гусака" Минздрава России</institution></aff><aff xml:lang="en"><institution>M. Gorky Donetsk State Medical University; V.K. Gusak Institute of Emergency and Reconstructive Surgery</institution></aff></aff-alternatives><aff-alternatives id="aff-6"><aff xml:lang="ru"><institution>ФГБОУ ВО "Омский государственный медицинский университет" Минздрава России</institution></aff><aff xml:lang="en"><institution>Omsk State Medical University</institution></aff></aff-alternatives><pub-date pub-type="collection"><year>2024</year></pub-date><pub-date pub-type="epub"><day>14</day><month>02</month><year>2025</year></pub-date><volume>23</volume><issue>12</issue><fpage>4234</fpage><lpage>4234</lpage><permissions><copyright-statement>Copyright &amp;#x00A9; Драпкина О.М., Бакиров Б.А., Бакирова А.Э., Кляритская И.Л., Максимова Е.В., Склянная Е.В., Ватутин Н.Т., Гарбузова Е.В., Ливзан М.А., Ершова А.И., 2025</copyright-statement><copyright-year>2025</copyright-year><copyright-holder xml:lang="ru">Драпкина О.М., Бакиров Б.А., Бакирова А.Э., Кляритская И.Л., Максимова Е.В., Склянная Е.В., Ватутин Н.Т., Гарбузова Е.В., Ливзан М.А., Ершова А.И.</copyright-holder><copyright-holder xml:lang="en">Drapkina O.M., Bakirov B.A., Bakirova A.E., Klyaritskaya I.L., Maksimova E.V., Sklyannaya E.V., Vatutin N.T., Garbuzova E.V., Livzan M.A., Ershova A.I.</copyright-holder><license xml:lang="ru" license-type="creative-commons-attribution" xlink:href="https://creativecommons.org/licenses/by/4.0/" xlink:type="simple"><license-p>Данная работа распространяется под лицензией Creative Commons Attribution 4.0.</license-p></license><license xml:lang="en" license-type="creative-commons-attribution" xlink:href="https://creativecommons.org/licenses/by/4.0/" xlink:type="simple"><license-p>This work is licensed under a Creative Commons Attribution 4.0 License.</license-p></license></permissions><self-uri xlink:href="https://cardiovascular.elpub.ru/jour/article/view/4234">https://cardiovascular.elpub.ru/jour/article/view/4234</self-uri><abstract><p>.</p></abstract><trans-abstract xml:lang="en"><p>.</p></trans-abstract><kwd-group xml:lang="ru"><kwd>совет по терапевтическим наукам РАН</kwd><kwd>кишечная микробиота</kwd></kwd-group><kwd-group xml:lang="en"><kwd>Council for Therapeutic Sciences of the Russian Academy of Sciences</kwd><kwd>intestinal microbiota</kwd></kwd-group></article-meta></front><back><ref-list><title>References</title><ref id="cit1"><label>1</label><citation-alternatives><mixed-citation xml:lang="ru">Boccio JR, Iyengar V. Iron deficiency: causes, consequences, and strategies to overcome this nutritional problem. Biol Trace Elem Res. 2003;94(1):1-32. doi:10.1385/BTER:94:1:1.</mixed-citation><mixed-citation xml:lang="en">Boccio JR, Iyengar V. Iron deficiency: causes, consequences, and strategies to overcome this nutritional problem. Biol Trace Elem Res. 2003;94(1):1-32. doi:10.1385/BTER:94:1:1.</mixed-citation></citation-alternatives></ref><ref id="cit2"><label>2</label><citation-alternatives><mixed-citation xml:lang="ru">Miller JL. Iron deficiency anemia: a common and curable disease. Cold Spring Harb Perspect Med. 2013;3(7):a011866. doi:10.1101/cshperspect.a011866.</mixed-citation><mixed-citation xml:lang="en">Miller JL. Iron deficiency anemia: a common and curable disease. Cold Spring Harb Perspect Med. 2013;3(7):a011866. doi:10.1101/cshperspect.a011866.</mixed-citation></citation-alternatives></ref><ref id="cit3"><label>3</label><citation-alternatives><mixed-citation xml:lang="ru">Cammarota G, Ianiro G, Bibbò S, et al. Gut microbiota modulation: probiotics, antibiotics or fecal microbiota transplantation? Intern Emerg Med. 2014;9(4):365-73. doi:10.1007/s11739-014-1069-4.</mixed-citation><mixed-citation xml:lang="en">Cammarota G, Ianiro G, Bibbò S, et al. Gut microbiota modulation: probiotics, antibiotics or fecal microbiota transplantation? Intern Emerg Med. 2014;9(4):365-73. doi:10.1007/s11739-014-1069-4.</mixed-citation></citation-alternatives></ref><ref id="cit4"><label>4</label><citation-alternatives><mixed-citation xml:lang="ru">Gabbianelli R, Damiani E. Epigenetics and neurodegeneration: role of early-life nutrition. J Nutr Biochem. 2018;57:1-13. doi:10.1016/j.jnutbio.2018.01.014.</mixed-citation><mixed-citation xml:lang="en">Gabbianelli R, Damiani E. Epigenetics and neurodegeneration: role of early-life nutrition. J Nutr Biochem. 2018;57:1-13. doi:10.1016/j.jnutbio.2018.01.014.</mixed-citation></citation-alternatives></ref><ref id="cit5"><label>5</label><citation-alternatives><mixed-citation xml:lang="ru">Kim YS, Unno T, Kim BY, et al. Sex Differences in Gut Microbiota. World J Mens Health. 2020;38(1):48-60. doi:10.5534/wjmh. 190009.</mixed-citation><mixed-citation xml:lang="en">Kim YS, Unno T, Kim BY, et al. Sex Differences in Gut Microbiota. World J Mens Health. 2020;38(1):48-60. doi:10.5534/wjmh. 190009.</mixed-citation></citation-alternatives></ref><ref id="cit6"><label>6</label><citation-alternatives><mixed-citation xml:lang="ru">Ursell LK, Metcalf JL, Parfrey LW, et al. Defining the human microbiome. Nutr Rev. 2012;70 Suppl 1(Suppl 1):S38-44. doi:10.1111/j.1753-4887.2012.00493.x.</mixed-citation><mixed-citation xml:lang="en">Ursell LK, Metcalf JL, Parfrey LW, et al. Defining the human microbiome. Nutr Rev. 2012;70 Suppl 1(Suppl 1):S38-44. doi:10.1111/j.1753-4887.2012.00493.x.</mixed-citation></citation-alternatives></ref><ref id="cit7"><label>7</label><citation-alternatives><mixed-citation xml:lang="ru">Eslam M, Newsome PN, Sarin SK, et al. A new definition for metabolic dysfunction-associated fatty liver disease: An international expert consensus statement. J Hepatol. 2020;73(1): 202-9. doi:10.1016/j.jhep.2020.03.039.</mixed-citation><mixed-citation xml:lang="en">Eslam M, Newsome PN, Sarin SK, et al. A new definition for metabolic dysfunction-associated fatty liver disease: An international expert consensus statement. J Hepatol. 2020;73(1): 202-9. doi:10.1016/j.jhep.2020.03.039.</mixed-citation></citation-alternatives></ref><ref id="cit8"><label>8</label><citation-alternatives><mixed-citation xml:lang="ru">Le MH, Yeo YH, Li X, et al. 2019 Global NAFLD Prevalence: A Systematic Review and Meta-analysis. Clin Gastroenterol Hepatol. 2022;20(12):2809-17.e28. doi:10.1016/j.cgh.2021.12.002.</mixed-citation><mixed-citation xml:lang="en">Le MH, Yeo YH, Li X, et al. 2019 Global NAFLD Prevalence: A Systematic Review and Meta-analysis. Clin Gastroenterol Hepatol. 2022;20(12):2809-17.e28. doi:10.1016/j.cgh.2021.12.002.</mixed-citation></citation-alternatives></ref><ref id="cit9"><label>9</label><citation-alternatives><mixed-citation xml:lang="ru">Yang S, Cheng J, Zhang R, et al. Metabolic dysfunctionassociated fatty liver disease and liver fibrosis: Prevalence and associated factors in the middle-aged and older US population. Hepatol Res. 2022;52(2):176-86. doi:10.1111/hepr.13728.</mixed-citation><mixed-citation xml:lang="en">Yang S, Cheng J, Zhang R, et al. Metabolic dysfunctionassociated fatty liver disease and liver fibrosis: Prevalence and associated factors in the middle-aged and older US population. Hepatol Res. 2022;52(2):176-86. doi:10.1111/hepr.13728.</mixed-citation></citation-alternatives></ref><ref id="cit10"><label>10</label><citation-alternatives><mixed-citation xml:lang="ru">Aron-Wisnewsky J, Vigliotti C, Witjes J, et al. Gut microbiota and human NAFLD: disentangling microbial signatures from metabolic disorders. Nat Rev Gastroenterol Hepatol. 2020;17(5): 279-97. doi:10.1038/s41575-020-0269-9.</mixed-citation><mixed-citation xml:lang="en">Aron-Wisnewsky J, Vigliotti C, Witjes J, et al. Gut microbiota and human NAFLD: disentangling microbial signatures from metabolic disorders. Nat Rev Gastroenterol Hepatol. 2020;17(5): 279-97. doi:10.1038/s41575-020-0269-9.</mixed-citation></citation-alternatives></ref><ref id="cit11"><label>11</label><citation-alternatives><mixed-citation xml:lang="ru">Martín-Mateos R, Albillos A. The Role of the Gut-Liver Axis in Metabolic Dysfunction-Associated Fatty Liver Disease. Front Immunol. 2021;12:660179.</mixed-citation><mixed-citation xml:lang="en">Martín-Mateos R, Albillos A. The Role of the Gut-Liver Axis in Metabolic Dysfunction-Associated Fatty Liver Disease. Front Immunol. 2021;12:660179.</mixed-citation></citation-alternatives></ref><ref id="cit12"><label>12</label><citation-alternatives><mixed-citation xml:lang="ru">Vallianou N, Christodoulatos GS, Karampela I, et al. Understanding the Role of the Gut Microbiome and Microbial Metabolites in NonAlcoholic Fatty Liver Disease: Current Evidence and Perspectives. Biomolecules. 2021;12(1):56. doi:10.3390/biom12010056.</mixed-citation><mixed-citation xml:lang="en">Vallianou N, Christodoulatos GS, Karampela I, et al. Understanding the Role of the Gut Microbiome and Microbial Metabolites in NonAlcoholic Fatty Liver Disease: Current Evidence and Perspectives. Biomolecules. 2021;12(1):56. doi:10.3390/biom12010056.</mixed-citation></citation-alternatives></ref><ref id="cit13"><label>13</label><citation-alternatives><mixed-citation xml:lang="ru">Sevcikova A, Izoldova N, Stevurkova V, et al. The Impact of the Microbiome on Resistance to Cancer Treatment with Chemotherapeutic Agents and Immunotherapy. Int. J. Mol. Sci. 2022;23: 488-517. doi:10.3390/ijms23010488.</mixed-citation><mixed-citation xml:lang="en">Sevcikova A, Izoldova N, Stevurkova V, et al. The Impact of the Microbiome on Resistance to Cancer Treatment with Chemotherapeutic Agents and Immunotherapy. Int. J. Mol. Sci. 2022;23: 488-517. doi:10.3390/ijms23010488.</mixed-citation></citation-alternatives></ref><ref id="cit14"><label>14</label><citation-alternatives><mixed-citation xml:lang="ru">Кожевников А. А., Раскина К. В., Мартынова Е. Ю. и др. Связь состояния кишечной микробиоты с заболеваниями человека и трансплантация микробиоты как способ восстановления ее нормального состава. РМЖ. 2017;1(2):92-8.</mixed-citation><mixed-citation xml:lang="en">Kozhevnikov AA, Raskina КV, Martynova EYu, et al. The relationship between the gut microbiota and human diseases, and the transplantation of microbiota as a way to restore its normal composition. RMJ. 2017;1(2):92-8. (In Russ.)</mixed-citation></citation-alternatives></ref><ref id="cit15"><label>15</label><citation-alternatives><mixed-citation xml:lang="ru">Xu H, Cao C, Ren Y, et al. Antitumor effects of fecal microbiota transplantation: Implications for microbiome modulation in cancer treatment. Front Immunol. 2022;13:949490. doi:10.3389/fimmu.2022.949490.</mixed-citation><mixed-citation xml:lang="en">Xu H, Cao C, Ren Y, et al. Antitumor effects of fecal microbiota transplantation: Implications for microbiome modulation in cancer treatment. Front Immunol. 2022;13:949490. doi:10.3389/fimmu.2022.949490.</mixed-citation></citation-alternatives></ref><ref id="cit16"><label>16</label><citation-alternatives><mixed-citation xml:lang="ru">Malard F, Vekhoff A, Lapusan S, et al. Gut microbiota diversity after autologous fecal microbiota transfer in acute myeloid leukemia patients. Nat Commun. 2021;12(1):3084. doi:10.1038/s41467-02123376-6.</mixed-citation><mixed-citation xml:lang="en">Malard F, Vekhoff A, Lapusan S, et al. Gut microbiota diversity after autologous fecal microbiota transfer in acute myeloid leukemia patients. Nat Commun. 2021;12(1):3084. doi:10.1038/s41467-02123376-6.</mixed-citation></citation-alternatives></ref></ref-list><fn-group><fn fn-type="conflict"><p>The authors declare that there are no conflicts of interest present.</p></fn></fn-group></back></article>
