cardiovascularКардиоваскулярная терапия и профилактикаCardiovascular Therapy and Prevention1728-88002619-0125«SILICEA-POLIGRAF» LLC10.15829/1728-8800-2024-4254DWZUMIcardiovascular-4254Research ArticleОБЗОРЫ ЛИТЕРАТУРЫREVIEW ARTICLESБиологический возраст: проблемы и перспективы. Обзор литературыBiological age: problems and prospects. Literature reviewhttps://orcid.org/0000-0003-1002-1895БернсС. А.BernsS. A.

Светлана Александровна Бернс — д.м.н., руководитель лаборатории патогенетических аспектов коморбидности, профессор кафедры терапии института профессионального образования и аккредитации.

Москва

Moscow

svberns@yandex.ruhttps://orcid.org/0000-0003-0068-8071СавичеваА. А.SavichevaA. A.

Алена Алексеевна Савичева — аспирант отдела фундаментальных и прикладных аспектов ожирения.

Москва

Moscow

alyona.sawi4ewa@yandex.ruhttps://orcid.org/0000-0002-8939-0716ИсайкинаО. Ю.IsaykinaO. Yu.

Олеся Юрьевна Исайкина — к.м.н., в.н.с. лаборатории применения амбулаторных диагностических методов в профилактике хронических неинфекционных заболеваний.

Москва

Moscow

oisaykina@gnicpm.ruhttps://orcid.org/0000-0001-9946-1015ВеремеевА. В.VeremeevA. V.

Алексей Владимирович Веремеев — к.м.н., советник директора.

Москва

Moscow

al.veremeev@gmail.comhttps://orcid.org/0000-0002-1423-214XГоршковА. Ю.GorshkovA. Yu.

к.м.н., зам. директора по научной и амбулаторно-поликлинической работе.

Москва

Moscow

https://orcid.org/0000-0002-4453-8430ДрапкинаО. М.DrapkinaO. M.

Оксана Михайловна Драпкина — академик РАН, д.м.н., профессор, директор.

Москва

Moscow

drapkina@bk.ruФГБУ "Национальный медицинский исследовательский центр терапии и профилактической медицины" Минздрава РоссииNational Medical Research Center for Therapy and Preventive Medicine202413022025231242544254Copyright © Бернс С.А., Савичева А.А., Исайкина О.Ю., Веремеев А.В., Горшков А.Ю., Драпкина О.М., 20252025Бернс С.А., Савичева А.А., Исайкина О.Ю., Веремеев А.В., Горшков А.Ю., Драпкина О.М.Berns S.A., Savicheva A.A., Isaykina O.Y., Veremeev A.V., Gorshkov A.Y., Drapkina O.M.Данная работа распространяется под лицензией Creative Commons Attribution 4.0.This work is licensed under a Creative Commons Attribution 4.0 License.https://cardiovascular.elpub.ru/jour/article/view/4254

Биологический возраст в последние годы привлекает повышенное внимание медицинского сообщества. Данный показатель является индивидуальным для каждого человека и в настоящее время не существует четкой классификации для разделения по группам, что могло бы помочь определить, является ли темп старения у определенного индивида нормальным или же идет по патологическому пути. На сегодняшний день учеными проводится большое количество клинических и лабораторных исследований для поиска оптимального маркера биологического старения, который соответствовал бы всем поставленным требованиям. Цель обзора — проанализировать и обобщить имеющиеся данные о механизмах возникновения старения, разработке новых маркеров биологического старения и калькуляторов, которые в будущем можно будет использовать в рутинной практике врача с целью предотвращения развития и прогрессирования хронических неинфекционных заболеваний.

Biological age has attracted increased attention of the medical community in recent years. It is individual for each person and currently there is no clear classification for dividing into groups that could help determine whether the rate of aging in a particular individual is normal or pathological. Today, scientists are conducting a large number of clinical and laboratory studies to find the optimal marker of biological aging that would meet all the requirements. The review aim is to analyze and summarize the available data on the mechanisms of aging, the development of novel markers of biological aging and calculators that can be used in routine practice in the future to prevent the development and progression of noncommunicable diseases.

биологический возрастстарениетемп старениямаркеры биологического старенияbiological ageagingrate of agingmarkers of biological agingРабота выполнена в рамках государственного задания № 123020600136-7 "Выявление ранних предикторов сердечно-сосудистых заболеваний и ассоциированных состояний по данным 40-летнего наблюдения за лицами мужского пола (результаты проспективного и комплексного одномоментного исследований)"The work was carried out within the state assignment № 123020600136-7 "Identification of early predictors of cardiovascular diseases and related conditions based on 40-year follow-up of males (results of prospective and comprehensive crosssectional studies)"ReferencesЖабоева С. Л., Радченко О. К. Медико-социальные возраст-ассоциированные синдромы как возможный объект профилактического воздействия. Геронтология. 2017;5(4):12-8.Zhaboeva SL, Radchenko OR. Medical-social age-associated syndromes as a possible object of preventive impact. Gerontology. 2017;5(4):12-8. 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The authors declare that there are no conflicts of interest present.