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<article article-type="research-article" dtd-version="1.3" xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink" xmlns:xsi="http://www.w3.org/2001/XMLSchema-instance" xml:lang="ru"><front><journal-meta><journal-id journal-id-type="publisher-id">cardiovascular</journal-id><journal-title-group><journal-title xml:lang="ru">Кардиоваскулярная терапия и профилактика</journal-title><trans-title-group xml:lang="en"><trans-title>Cardiovascular Therapy and Prevention</trans-title></trans-title-group></journal-title-group><issn pub-type="ppub">1728-8800</issn><issn pub-type="epub">2619-0125</issn><publisher><publisher-name>«SILICEA-POLIGRAF» LLC</publisher-name></publisher></journal-meta><article-meta><article-id pub-id-type="doi">10.15829/1728-8800-2026-4726</article-id><article-id custom-type="edn" pub-id-type="custom">OVZFIF</article-id><article-id custom-type="elpub" pub-id-type="custom">cardiovascular-4726</article-id><article-categories><subj-group subj-group-type="heading"><subject>Research Article</subject></subj-group><subj-group subj-group-type="section-heading" xml:lang="ru"><subject>ФИБРИЛЛЯЦИЯ ПРЕДСЕРДИЙ</subject></subj-group><subj-group subj-group-type="section-heading" xml:lang="en"><subject>ATRIAL FIBRILLATION</subject></subj-group></article-categories><title-group><article-title>Влияние показателей электролитного состава крови на частоту возникновения пароксизмов фибрилляции предсердий у пациентов с хронической болезнью почек в сочетании с альбуминурией и без нее</article-title><trans-title-group xml:lang="en"><trans-title>Impact of blood electrolyte parameters on the incidence of paroxysmal atrial fibrillation in patients with chronic kidney disease with and without albuminuria</trans-title></trans-title-group></title-group><contrib-group><contrib contrib-type="author" corresp="yes"><contrib-id contrib-id-type="orcid">https://orcid.org/0000-0002-2157-544X</contrib-id><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Рахматуллов</surname><given-names>Р. Ф.</given-names></name><name name-style="western" xml:lang="en"><surname>Rakhmatullov</surname><given-names>R. F.</given-names></name></name-alternatives><bio xml:lang="ru"><p>К.м.н., доцент, доцент кафедры "Внутренние болезни" </p><p>ул. Красная, д. 40, Пенза, 440026</p></bio><bio xml:lang="en"><p>Krasnaya str., 40, Penza, 4400026</p></bio><email xlink:type="simple">capitalofgreat@icloud.com</email><xref ref-type="aff" rid="aff-1"/></contrib><contrib contrib-type="author" corresp="yes"><contrib-id contrib-id-type="orcid">https://orcid.org/0009-0008-2668-8567</contrib-id><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Шаталина</surname><given-names>Л. К.</given-names></name><name name-style="western" xml:lang="en"><surname>Shatalina</surname><given-names>L. K.</given-names></name></name-alternatives><bio xml:lang="ru"><p>Ассистент кафедры "Внутренние болезни" </p><p>ул. Красная, д. 40, Пенза, 440026</p></bio><bio xml:lang="en"><p>Krasnaya str., 40, Penza, 4400026</p></bio><email xlink:type="simple">lisonka0807@gmail.com</email><xref ref-type="aff" rid="aff-1"/></contrib><contrib contrib-type="author" corresp="yes"><contrib-id contrib-id-type="orcid">https://orcid.org/0000-0003-1497-5338</contrib-id><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Дементьева</surname><given-names>Р. Е.</given-names></name><name name-style="western" xml:lang="en"><surname>Dementieva</surname><given-names>R. E.</given-names></name></name-alternatives><bio xml:lang="ru"><p>К.м.н., доцент, доцент кафедры "Внутренние болезни" </p><p>ул. Красная, д. 40, Пенза, 440026</p></bio><bio xml:lang="en"><p>Krasnaya str., 40, Penza, 4400026</p></bio><email xlink:type="simple">rdementyeva@gmail.com</email><xref ref-type="aff" rid="aff-1"/></contrib><contrib contrib-type="author" corresp="yes"><contrib-id contrib-id-type="orcid">https://orcid.org/0000-0002-2587-8325</contrib-id><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Рахматуллов</surname><given-names>Ф. К.</given-names></name><name name-style="western" xml:lang="en"><surname>Rakhmatullov</surname><given-names>F. K.</given-names></name></name-alternatives><bio xml:lang="ru"><p>Д.м.н., профессор, заведующий кафедрой "Внутренние болезни" </p><p>ул. Красная, д. 40, Пенза, 440026</p></bio><bio xml:lang="en"><p>Krasnaya str., 40, Penza, 4400026</p></bio><email xlink:type="simple">fagimrakhmatullov@gmail.com</email><xref ref-type="aff" rid="aff-1"/></contrib><contrib contrib-type="author" corresp="yes"><contrib-id contrib-id-type="orcid">https://orcid.org/0000-0003-4688-1272</contrib-id><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Мельникова</surname><given-names>Л. В.</given-names></name><name name-style="western" xml:lang="en"><surname>Melnikova</surname><given-names>L. V.</given-names></name></name-alternatives><bio xml:lang="ru"><p>Д.м.н., профессор, профессор кафедры «Общая врачебная практика и поликлиническая терапия» </p><p>ул. Баррикадная, д. 2/1, стр. 1, Москва, 125993</p></bio><bio xml:lang="en"><p>Barricadnaya str., 2/1, bld. 1, Moscow, 125993</p></bio><email xlink:type="simple">pgu-vb2004@mail.ru</email><xref ref-type="aff" rid="aff-2"/></contrib><contrib contrib-type="author" corresp="yes"><contrib-id contrib-id-type="orcid">https://orcid.org/0000-0001-9750-0770</contrib-id><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Шибаева</surname><given-names>Т. М.</given-names></name><name name-style="western" xml:lang="en"><surname>Shibaeva</surname><given-names>T. M.</given-names></name></name-alternatives><bio xml:lang="ru"><p>К.м.н., доцент, доцент кафедры "Внутренние болезни" </p><p>ул. Красная, д. 40, Пенза, 440026</p></bio><bio xml:lang="en"><p>Krasnaya str., 40, Penza, 4400026</p></bio><email xlink:type="simple">pgu-vb2004@mail.ru</email><xref ref-type="aff" rid="aff-1"/></contrib></contrib-group><aff-alternatives id="aff-1"><aff xml:lang="ru"><institution>ФГБОУ ВО "Пензенский государственный университет"</institution></aff><aff xml:lang="en"><institution>Penza State University</institution></aff></aff-alternatives><aff-alternatives id="aff-2"><aff xml:lang="ru"><institution>ФГБОУ ДПО "Российская медицинская академия непрерывного профессионального образования" Минздрава России</institution></aff><aff xml:lang="en"><institution>Russian Medical Academy of Continuous Professional Education</institution></aff></aff-alternatives><pub-date pub-type="collection"><year>2026</year></pub-date><pub-date pub-type="epub"><day>13</day><month>06</month><year>2026</year></pub-date><volume>25</volume><issue>5</issue><fpage>4726</fpage><lpage>4726</lpage><permissions><copyright-statement>Copyright &amp;#x00A9; Рахматуллов Р.Ф., Шаталина Л.К., Дементьева Р.Е., Рахматуллов Ф.К., Мельникова Л.В., Шибаева Т.М., 2026</copyright-statement><copyright-year>2026</copyright-year><copyright-holder xml:lang="ru">Рахматуллов Р.Ф., Шаталина Л.К., Дементьева Р.Е., Рахматуллов Ф.К., Мельникова Л.В., Шибаева Т.М.</copyright-holder><copyright-holder xml:lang="en">Rakhmatullov R.F., Shatalina L.K., Dementieva R.E., Rakhmatullov F.K., Melnikova L.V., Shibaeva T.M.</copyright-holder><license xml:lang="ru" license-type="creative-commons-attribution" xlink:href="https://creativecommons.org/licenses/by/4.0/" xlink:type="simple"><license-p>Данная работа распространяется под лицензией Creative Commons Attribution 4.0.</license-p></license><license xml:lang="en" license-type="creative-commons-attribution" xlink:href="https://creativecommons.org/licenses/by/4.0/" xlink:type="simple"><license-p>This work is licensed under a Creative Commons Attribution 4.0 License.</license-p></license></permissions><self-uri xlink:href="https://cardiovascular.elpub.ru/jour/article/view/4726">https://cardiovascular.elpub.ru/jour/article/view/4726</self-uri><abstract><sec><title>Цель</title><p>Цель. Оценить влияние электролитов крови, паратиреоидного гормона и витамина D на частоту пароксизмов (ПФП) фибрилляции предсердий (ФП) у больных хронической болезнью почек (ХБП) с умеренно сниженной функцией на фоне альбуминурии и без нее.</p></sec><sec><title>Материал и методы</title><p>Материал и методы. Обследовано 76 пациентов с пароксизмальной формой ФП, которые были разделены на три группы. В первую группу вошли 23 пациента с ФП без ХБП, во вторую группу объединены 28 пациентов — с ФП и ХБП, в третью группу вошли 25 пациентов с ФП и ХБП с альбуминурией. Диагноз во всех случаях был подтвержден анамнестическими, клиническими, электрокардиографическими и лабораторными данными. Прогнозирование клинического течения ФП проводили с помощью множественной линейной регрессии. Уравнение множественной регрессии имеет вид: Yx = a0 + b1´X1 + b2´X2 + b3´X3, где Yx — зависимая переменная, a0 — свободный член, b1,2,3 — коэффициенты регрессии, X1,2,3 — независимые переменные.</p></sec><sec><title>Результаты</title><p>Результаты. Установлена тесная связь частоты ПФП при ХБП С3а стадии с уровнем электролитов крови, паратиреоидным гормоном, витамином D. Разработана математическая модель прогнозирования частоты возникновения ПФП у пациентов на основании электролитов крови, паратиреоидного гормона, витамина D при ХБП С3а стадии.</p></sec><sec><title>Заключение</title><p>Заключение. Уровни электролитов крови, паратиреоидного гормона и уровень витамина D можно использовать для построения прогностической модели для оценки возникновения частоты пароксизмов ФП.</p></sec></abstract><trans-abstract xml:lang="en"><sec><title>Aim</title><p>Aim. To evaluate the impact of blood electrolytes, parathyroid hormone, and vitamin D on the incidence of paroxysmal atrial fibrillation (AF) in patients with chronic kidney disease (CKD) with and without albuminuria.</p></sec><sec><title>Material and methods</title><p>Material and methods. A total of 76 patients with paroxysmal AF were examined and divided into three groups. The first group included 23 patients with AF but no CKD, while the second group — 28 patients with AF and CKD, and the third group — 25 patients with AF and CKD and albuminuria. The diagnosis in all cases was confirmed by anamnestic, clinical, electrocardiographic, and laboratory data. Prediction of the clinical course of AF was performed using multiple linear regression. There is a following multiple regression equation: Yx = a0 + b1´X1 + b2´X2 + b3´X3, where Yx is the dependent variable, a0 is the intercept, b1,2,3 are the regression coefficients, and X1,2,3 are the independent variables.</p></sec><sec><title>Results</title><p>Results. A close relationship has been established between the incidence of atrial fibrillation in stage C3a CKD and blood electrolyte levels, parathyroid hormone, and vitamin D. A mathematical model for predicting the incidence of atrial fibrillation in patients with stage C3a CKD was developed based on blood electrolytes, parathyroid hormone, and vitamin D levels.</p></sec><sec><title>Conclusion</title><p>Conclusion. Blood electrolyte levels, parathyroid hormone, and vitamin D levels can be used to construct a predictive model for estimating the incidence of paroxysmal atrial fibrillation.</p></sec></trans-abstract><kwd-group xml:lang="ru"><kwd>фибрилляция предсердий</kwd><kwd>электролиты крови</kwd><kwd>хроническая болезнь почек</kwd><kwd>альбуминурия</kwd><kwd>математическая модель</kwd><kwd>множественная линейная регрессия</kwd></kwd-group><kwd-group xml:lang="en"><kwd>atrial fibrillation</kwd><kwd>blood electrolytes</kwd><kwd>chronic kidney disease</kwd><kwd>albuminuria</kwd><kwd>mathematical model</kwd><kwd>multiple linear regression</kwd></kwd-group></article-meta></front><back><ref-list><title>References</title><ref id="cit1"><label>1</label><citation-alternatives><mixed-citation xml:lang="ru">Дру­жи­лов М. А., Кузнецова Т. Ю., Дружилова О. Ю. и др. Фибрил­ляция предсердий и хроническая болезнь почек: основные клинические характеристики пациентов в отдельных субъектах Российской Федерации. 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