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<article article-type="research-article" dtd-version="1.3" xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink" xmlns:xsi="http://www.w3.org/2001/XMLSchema-instance" xml:lang="ru"><front><journal-meta><journal-id journal-id-type="publisher-id">cardiovascular</journal-id><journal-title-group><journal-title xml:lang="ru">Кардиоваскулярная терапия и профилактика</journal-title><trans-title-group xml:lang="en"><trans-title>Cardiovascular Therapy and Prevention</trans-title></trans-title-group></journal-title-group><issn pub-type="ppub">1728-8800</issn><issn pub-type="epub">2619-0125</issn><publisher><publisher-name>«SILICEA-POLIGRAF» LLC</publisher-name></publisher></journal-meta><article-meta><article-id custom-type="elpub" pub-id-type="custom">cardiovascular-911</article-id><article-categories><subj-group subj-group-type="heading"><subject>Research Article</subject></subj-group><subj-group subj-group-type="section-heading" xml:lang="ru"><subject>ИШЕМИЧЕСКАЯ БОЛЕЗНЬ СЕРДЦА</subject></subj-group><subj-group subj-group-type="section-heading" xml:lang="en"><subject>CORONARY HEART DISEASE</subject></subj-group></article-categories><title-group><article-title>Кальцификация клапанов сердца у больных ишемической болезнью сердца</article-title><trans-title-group xml:lang="en"><trans-title>Heart valve calcification in patients with coronary heart disease</trans-title></trans-title-group></title-group><contrib-group><contrib contrib-type="author" corresp="yes"><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Довголис</surname><given-names>С. А.</given-names></name><name name-style="western" xml:lang="en"><surname>Dovgolis</surname><given-names>S. A.</given-names></name></name-alternatives><bio xml:lang="ru"/><email xlink:type="simple">kucherova@mtu-net.ru</email><xref ref-type="aff" rid="aff-1"/></contrib><contrib contrib-type="author" corresp="yes"><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Кучерова</surname><given-names>И. Ю.</given-names></name><name name-style="western" xml:lang="en"><surname>Kucherova</surname><given-names>I. Yu.</given-names></name></name-alternatives><bio xml:lang="ru"/><email xlink:type="simple">kucherova@mtu-net.ru</email><xref ref-type="aff" rid="aff-1"/></contrib><contrib contrib-type="author" corresp="yes"><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Козлов</surname><given-names>Э. А.</given-names></name><name name-style="western" xml:lang="en"><surname>Kozlov</surname><given-names>E. A.</given-names></name></name-alternatives><bio xml:lang="ru"/><email xlink:type="simple">kucherova@mtu-net.ru</email><xref ref-type="aff" rid="aff-1"/></contrib><contrib contrib-type="author" corresp="yes"><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Фомина</surname><given-names>И. Г.</given-names></name><name name-style="western" xml:lang="en"><surname>Fomina</surname><given-names>I. G.</given-names></name></name-alternatives><bio xml:lang="ru"/><email xlink:type="simple">kucherova@mtu-net.ru</email><xref ref-type="aff" rid="aff-1"/></contrib></contrib-group><aff-alternatives id="aff-1"><aff xml:lang="ru"><institution>Московская медицинская академия им. И.М.Сеченова, Москва</institution></aff><aff xml:lang="en"><institution>I.M. Sechenov Moscow Medical Academy, Moscow</institution></aff></aff-alternatives><pub-date pub-type="collection"><year>2005</year></pub-date><pub-date pub-type="epub"><day>20</day><month>02</month><year>2005</year></pub-date><volume>4</volume><issue>1</issue><fpage>62</fpage><lpage>65</lpage><permissions><copyright-statement>Copyright &amp;#x00A9; Довголис С.А., Кучерова И.Ю., Козлов Э.А., Фомина И.Г., 2005</copyright-statement><copyright-year>2005</copyright-year><copyright-holder xml:lang="ru">Довголис С.А., Кучерова И.Ю., Козлов Э.А., Фомина И.Г.</copyright-holder><copyright-holder xml:lang="en">Dovgolis S.A., Kucherova I.Y., Kozlov E.A., Fomina I.G.</copyright-holder><license xml:lang="ru" license-type="creative-commons-attribution" xlink:href="https://creativecommons.org/licenses/by/4.0/" xlink:type="simple"><license-p>Данная работа распространяется под лицензией Creative Commons Attribution 4.0.</license-p></license><license xml:lang="en" license-type="creative-commons-attribution" xlink:href="https://creativecommons.org/licenses/by/4.0/" xlink:type="simple"><license-p>This work is licensed under a Creative Commons Attribution 4.0 License.</license-p></license></permissions><self-uri xlink:href="https://cardiovascular.elpub.ru/jour/article/view/911">https://cardiovascular.elpub.ru/jour/article/view/911</self-uri><abstract><p>Цель. Изучить частоту кальцификации митрального и аортального клапанов сердца у больных ишемической болезнью сердца (ИБС), влияние ее на состояние миокарда. Материал и методы. Методом эхокардиографии обследовали 214 пациентов, страдающих ИБС, среди них 119 женщин и 95 мужчин, средний возраст 59,0±8,3 года. Результаты. Кальцификаты на аортальном и митральном клапанах сердца обнаружены у 74 (34,5%) больных ИБС, среди них 50 (68%) женщин, все больные &gt; 40 лет, 46% больных &gt; 70 лет. У 26 (35%) больных имело место сочетание ИБС и артериальной гипертонии (АГ). В 86% случаев поражен аортальный клапан, в 53% — митральный. Регургитация обнаружена у 17 (23%) пациентов, дилатация левого предсердия и диастолическая дисфункция — у 89%, гипертрофия левого желудочка (ГЛЖ) — у 74% больных. Заключение. Пациенты с кальцификатами принадлежат к более старшим возрастным группам, среди них преобладают женщины, у них чаще встречаются АГ и сахарный диабет. Наиболее часто кальцификаты обнаруживались на аортальном клапане, частота кальцификации митрального клапана увеличивалась с возрастом. Частота дилатации левого предсердия, ГЛЖ и диастолической дисфункции миокарда оказалась на 8%, 19% и 13% соответственно, выше по сравнению с больными без кальцификации клапанов. Фракция выброса имела одинаковые значения в обеих группах больных.</p></abstract><trans-abstract xml:lang="en"><p>Aim. To study mitral and aortic valve calcification prevalence in patients with coronary heart disease (CHD), and its influence on myocardial status. Material and methods. Echocardiography was performed in 214 CHD patients (119 females, 95 males; mean age 59.0±8.3 years). Mitral and aortic valve calcification, regurgitation, ejection fraction, diastolic dysfunction, left cardiac chamber sizes, and atherosclerosis risk factors were studied. Results. Calcification of aortial and mitral valves was found in 74 (34.5%) patients with CHD. All of them were above 40, 46% - older than 70; 50 (68%) patients were females. Combination of CHD and arterial hypertension (AH) was observed in 26 (35%) patients. Aortic or mitral valve calcification was found in 86% and 53% of the cases, respectively. Regurgitation was observed in 17 (23%) participants, left atrial dilatation and diastolic dysfunction – in 89%, left ventricular hypertrophy – in 74%. Conclusions: Aortic and mitral valve calcification was observed in 74 (35.5%) participants with CHD. Most of these patients were above 60 years, females, suffering from AH and diabetes mellitus. Aortic valve was affected in 86% of the cases; frequency of mitral calcification increased with age. The prevalence of left atrial dilatation, left ventricular hypertrophy and diastolic dysfunction was higher by 8%, 19%, and 13%, respectively, than that in individuals with intact valves. Ejection fraction did not differ in both groups.</p></trans-abstract><kwd-group xml:lang="ru"><kwd>кальцификация</kwd><kwd>аортальный клапан</kwd><kwd>митральный клапан</kwd><kwd>ишемическая болезнь сердца</kwd><kwd>артериальная гипертензия</kwd><kwd>атеросклероз</kwd></kwd-group><kwd-group xml:lang="en"><kwd>calcification</kwd><kwd>aortic valve</kwd><kwd>mitral valve</kwd><kwd>coronary heart disease</kwd><kwd>arterial hypertension</kwd><kwd>atherosclerosis</kwd></kwd-group></article-meta></front><back><ref-list><title>References</title><ref id="cit1"><label>1</label><citation-alternatives><mixed-citation xml:lang="ru">Agmon Y, Khandheria BK, Meissner I, et al. Aortic valve sclerosis and aortic atherosclerois: different manifestations of the same disease? JACC 2001; 38: 827-34.</mixed-citation><mixed-citation xml:lang="en">Agmon Y, Khandheria BK, Meissner I, et al. Aortic valve sclerosis and aortic atherosclerois: different manifestations of the same disease? 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