cardiovascularКардиоваскулярная терапия и профилактикаCardiovascular Therapy and Prevention1728-88002619-0125«SILICEA-POLIGRAF» LLCcardiovascular-979Research ArticleПЕРЕДОВАЯ СТАТЬЯEDITORIALБета-адреноблокаторы. Принципы терапии в свете международных рекомендацийBeta-adrenoblockers: treatment principles in international clinical guidelinesМарцевичС. Ю.MartsevichS. Yu.oganov@online.ruГосударственный научно-исследовательский центр профилактической медицины Росздрава, МоскваState Research Center for Preventive Medicine, Ministry of Health of the Russian Federation, Moscow2005200820054449Copyright © Марцевич С.Ю., 20052005Марцевич С.Ю.Martsevich S.Y.Данная работа распространяется под лицензией Creative Commons Attribution 4.0.This work is licensed under a Creative Commons Attribution 4.0 License.https://cardiovascular.elpub.ru/jour/article/view/979

В статье приводятся данные об эффективности бета-блокаторов в кардиологии, полученные в крупных, рандомизированных исследованиях и сформулированные на основании этих данных рекомендации по их клиническому использованию.

The article contains data on beta-blocker efficacy in cardiology – the results of large, randomized clinical trials, and evidence-based clinical guidelines on beta-blocker therapy.

сердечно-сосудистые заболеваниябета-блокаторыпринципы терапииcardiovascular diseasebeta-blockerstreatment principlesReferencesKo DT, Hebert PR, Coffey CS, et al. β-Blocker therapy and symptoms of depression, fatigue, and sexual dysfunction. JAMA 2002; 288: 351-7.Ko DT, Hebert PR, Coffey CS, et al. β-Blocker therapy and symptoms of depression, fatigue, and sexual dysfunction. JAMA 2002; 288: 351-7.ACC/AHA/ACP-ACIM Guidelines for the management of patients with chronic stable angina. A report of the American College of Cardiology/American Heart Association Task Force on Practice Guidelines. JACC 2003; 41: 159-68.ACC/AHA/ACP-ACIM Guidelines for the management of patients with chronic stable angina. A report of the American College of Cardiology/American Heart Association Task Force on Practice Guidelines. JACC 2003; 41: 159-68.von Arnim T, TIBBS Investigators. Medical treatment to reduce total ischemic burden: Total Ischemic Burden Bisoprolol Study (TIBBS), a mutticenter trial comparing bisoprolol and nifedipine. JACC1995; 25: 231-8.von Arnim T, TIBBS Investigators. Medical treatment to reduce total ischemic burden: Total Ischemic Burden Bisoprolol Study (TIBBS), a mutticenter trial comparing bisoprolol and nifedipine. JACC1995; 25: 231-8.Beta-blocker Heart Attack Trial Research Group (BHAT). A randomized trial of propranolol in patients with acute myocardial infarction. JAMA 1982; 247: 1707-14.Beta-blocker Heart Attack Trial Research Group (BHAT). A randomized trial of propranolol in patients with acute myocardial infarction. JAMA 1982; 247: 1707-14.Wikstrand J, Warnold I, Tuomilehto J, et al. Metoprolol versus thiazide diuretics in hypertension. Morbidity results from MAPHY study. Hypertension 1991; 17: 570-88.Wikstrand J, Warnold I, Tuomilehto J, et al. Metoprolol versus thiazide diuretics in hypertension. Morbidity results from MAPHY study. Hypertension 1991; 17: 570-88.Plevan A, Lehmann G, Ndrepepa G, et al. Maintenance of sinus rythm afterelectrical cardioversion of presistent atrial fibrillation. Sotalol vs bisoprolo. Eur Heart J 2001; 22: 1504-10Plevan A, Lehmann G, Ndrepepa G, et al. Maintenance of sinus rythm afterelectrical cardioversion of presistent atrial fibrillation. Sotalol vs bisoprolo. Eur Heart J 2001; 22: 1504-10MERIT-HF Study Group. Effect of metoprolol CR/HL in chronic heart failure: metoprolol CR/HL Randomised Intervention Trial in Congestive Heart Failure (MERIT-HF). Lancet 1999; 353: 2001-7.MERIT-HF Study Group. Effect of metoprolol CR/HL in chronic heart failure: metoprolol CR/HL Randomised Intervention Trial in Congestive Heart Failure (MERIT-HF). Lancet 1999; 353: 2001-7.CIBIS-II Investigators and Committees. The Cardiac Insufficiency Bisoprolol Study II (CIBIS-II): a randomized trial. Lancet 1999; 353: 9-13.CIBIS-II Investigators and Committees. The Cardiac Insufficiency Bisoprolol Study II (CIBIS-II): a randomized trial. Lancet 1999; 353: 9-13.Poldermans D, Boersma E, Bax J, et al. The effect of bisoprolol on perioperative mortality and myocardial infarction in high-risk patients undergoing vascular surgery. N Engl J Med 1999; 341: 1789-94.Poldermans D, Boersma E, Bax J, et al. The effect of bisoprolol on perioperative mortality and myocardial infarction in high-risk patients undergoing vascular surgery. N Engl J Med 1999; 341: 1789-94.Viskin S, Kitzis I, Lev E, et al. Treatment with beta-adrenergic blocking agents after myocardial infarction: from randomized trials to clinical practice. JACC 1995; 25: 1327-32.Viskin S, Kitzis I, Lev E, et al. Treatment with beta-adrenergic blocking agents after myocardial infarction: from randomized trials to clinical practice. JACC 1995; 25: 1327-32.Guidelines Committee. 2003 European Society of Hypertension-European Society of Cardiology guidelines for the management of arterial hypertension. J Hypertens 2003; 21: 1011-53.Guidelines Committee. 2003 European Society of Hypertension-European Society of Cardiology guidelines for the management of arterial hypertension. J Hypertens 2003; 21: 1011-53.Task Force Members, Lopez-Sendon J, Swedberg K, et al. Expert consensus document on beta-blockers of the European Society of Cardiology. Eur Heart J 2004; 25:1341-62.Task Force Members, Lopez-Sendon J, Swedberg K, et al. Expert consensus document on beta-blockers of the European Society of Cardiology. Eur Heart J 2004; 25:1341-62.Ambrosioni E, Leonetti G, Pessina A, et al. Patterns of hypertension management in Italy : results of a pharmacoepidemiological survey on antihypertensive therapy. J Hypertens 2000; 18: 1691-9.Ambrosioni E, Leonetti G, Pessina A, et al. Patterns of hypertension management in Italy : results of a pharmacoepidemiological survey on antihypertensive therapy. J Hypertens 2000; 18: 1691-9.Марцевич С.Ю. Лечение артериальной гипертонии дигидропиридиновыми антагонистами кальция в виде монотерапии и в комбинации с бета-адреноблокаторами. РКЖ 2002; 3(35): 72-5.Марцевич С.Ю. Лечение артериальной гипертонии дигидропиридиновыми антагонистами кальция в виде монотерапии и в комбинации с бета-адреноблокаторами. РКЖ 2002; 3(35): 72-5.UK Prospective Diabetes Study Group. Efficacy of atenolol and captopril in reducing risk of macrovascular and microvascular complications in type II diabetes: UKPDS 39. BMJ 1998; 317: 713-20.UK Prospective Diabetes Study Group. Efficacy of atenolol and captopril in reducing risk of macrovascular and microvascular complications in type II diabetes: UKPDS 39. BMJ 1998; 317: 713-20.

The authors declare that there are no conflicts of interest present.