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<article article-type="research-article" dtd-version="1.3" xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink" xmlns:xsi="http://www.w3.org/2001/XMLSchema-instance" xml:lang="ru"><front><journal-meta><journal-id journal-id-type="publisher-id">cardiovascular</journal-id><journal-title-group><journal-title xml:lang="ru">Кардиоваскулярная терапия и профилактика</journal-title><trans-title-group xml:lang="en"><trans-title>Cardiovascular Therapy and Prevention</trans-title></trans-title-group></journal-title-group><issn pub-type="ppub">1728-8800</issn><issn pub-type="epub">2619-0125</issn><publisher><publisher-name>«SILICEA-POLIGRAF» LLC</publisher-name></publisher></journal-meta><article-meta><article-id custom-type="elpub" pub-id-type="custom">cardiovascular-984</article-id><article-categories><subj-group subj-group-type="heading"><subject>Research Article</subject></subj-group><subj-group subj-group-type="section-heading" xml:lang="ru"><subject>ИШЕМИЧЕСКАЯ БОЛЕЗНЬ СЕРДЦА</subject></subj-group><subj-group subj-group-type="section-heading" xml:lang="en"><subject>CORONARY HEART DISEASE</subject></subj-group></article-categories><title-group><article-title>Связь семейного анамнеза и ишемической болезни сердца в популяции города Новосибирска (программа ВОЗ MONICA)</article-title><trans-title-group xml:lang="en"><trans-title>Family history and coronary heart disease in Novosibirsk City population (Program WHO-MONICA)</trans-title></trans-title-group></title-group><contrib-group><contrib contrib-type="author" corresp="yes"><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Никитин</surname><given-names>Ю. П.</given-names></name><name name-style="western" xml:lang="en"><surname>Nikitin</surname><given-names>Yu. P.</given-names></name></name-alternatives><email xlink:type="simple">medik@mezon.nsk.su</email><xref ref-type="aff" rid="aff-1"/></contrib><contrib contrib-type="author" corresp="yes"><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Воевода</surname><given-names>М. И.</given-names></name><name name-style="western" xml:lang="en"><surname>Voevoda</surname><given-names>M. I.</given-names></name></name-alternatives><email xlink:type="simple">medik@mezon.nsk.su</email><xref ref-type="aff" rid="aff-1"/></contrib><contrib contrib-type="author" corresp="yes"><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Максимов</surname><given-names>В. Н.</given-names></name><name name-style="western" xml:lang="en"><surname>Maksimov</surname><given-names>V. N.</given-names></name></name-alternatives><email xlink:type="simple">medik@mezon.nsk.su</email><xref ref-type="aff" rid="aff-1"/></contrib><contrib contrib-type="author" corresp="yes"><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Лисиченко</surname><given-names>О. В.</given-names></name><name name-style="western" xml:lang="en"><surname>Lisichenko</surname><given-names>O. V.</given-names></name></name-alternatives><email xlink:type="simple">medik@mezon.nsk.su</email><xref ref-type="aff" rid="aff-1"/></contrib><contrib contrib-type="author" corresp="yes"><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Малютина</surname><given-names>С. К.</given-names></name><name name-style="western" xml:lang="en"><surname>Malyutina</surname><given-names>C. K.</given-names></name></name-alternatives><email xlink:type="simple">medik@mezon.nsk.su</email><xref ref-type="aff" rid="aff-1"/></contrib><contrib contrib-type="author" corresp="yes"><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Гафаров</surname><given-names>В. В.</given-names></name><name name-style="western" xml:lang="en"><surname>Gafarov</surname><given-names>V. V.</given-names></name></name-alternatives><email xlink:type="simple">medik@mezon.nsk.su</email><xref ref-type="aff" rid="aff-1"/></contrib></contrib-group><aff-alternatives id="aff-1"><aff xml:lang="ru"><institution>Государственное учреждение Научно-исследовательский институт терапии СО РАМН, Новосибирск</institution></aff><aff xml:lang="en"><institution>State Research Institute of Internal Diseases, Siberian Branch of the Russian Academy of Medical Science, Novosibirsk</institution></aff></aff-alternatives><pub-date pub-type="collection"><year>2005</year></pub-date><pub-date pub-type="epub"><day>20</day><month>08</month><year>2005</year></pub-date><volume>4</volume><issue>4</issue><fpage>37</fpage><lpage>40</lpage><permissions><copyright-statement>Copyright &amp;#x00A9; Никитин Ю.П., Воевода М.И., Максимов В.Н., Лисиченко О.В., Малютина С.К., Гафаров В.В., 2005</copyright-statement><copyright-year>2005</copyright-year><copyright-holder xml:lang="ru">Никитин Ю.П., Воевода М.И., Максимов В.Н., Лисиченко О.В., Малютина С.К., Гафаров В.В.</copyright-holder><copyright-holder xml:lang="en">Nikitin Y.P., Voevoda M.I., Maksimov V.N., Lisichenko O.V., Malyutina C.K., Gafarov V.V.</copyright-holder><license xml:lang="ru" license-type="creative-commons-attribution" xlink:href="https://creativecommons.org/licenses/by/4.0/" xlink:type="simple"><license-p>Данная работа распространяется под лицензией Creative Commons Attribution 4.0.</license-p></license><license xml:lang="en" license-type="creative-commons-attribution" xlink:href="https://creativecommons.org/licenses/by/4.0/" xlink:type="simple"><license-p>This work is licensed under a Creative Commons Attribution 4.0 License.</license-p></license></permissions><self-uri xlink:href="https://cardiovascular.elpub.ru/jour/article/view/984">https://cardiovascular.elpub.ru/jour/article/view/984</self-uri><abstract><p>Цель. Изучить связь семейного анамнеза с определенной ишемической болезнью сердца (ОИБС) в популяции 25-64-летних жителей г. Новосибирска по данным одномоментных эпидемиологических исследований. Материал и методы. В рамках программы ВОЗ MONICA обследованы 7111 мужчин и 5523 женщины из неорганизованной популяции г.Новосибирска. Для выявления факторов, независимо влияющих на риск развития ОИБС, проведен множественный пошаговый логистический регрессионный анализ. Результаты. Распространенность наследственной отягощенности (НО) по ИБС у мужчин – 26,8%, у женщин – 37,7%. Независимые факторы, статистически значимо повышающие риск иметь ОИБС у мужчин: увеличение возраста (OR=1,10), индекса атерогенности (ИА) (OR=1,10), индекса массы тела (OR=1,04), артериальная гипертензия (АГ) (OR=1,63), НО по ИБС (OR=1,71), АГ у сестер (OR=1,63), АГ у родителей (OR=1,41). У женщин: увеличение возраста (OR=1,06), ИА (OR=1,13), АГ (OR=2,0), смерть матери от сердечного приступа (OR=2,28), перемежающаяся хромота у отца (OR=4,13), сахарный диабет у родителей (OR=1,59). Заключение. НО по ИБС в популяции является независимым фактором риска развития ИБС и, благодаря значительной распространенности и простоте определения, может использоваться как один из критериев для формирования групп повышенного риска с целью проведения первичной профилактики.</p></abstract><trans-abstract xml:lang="en"><p>Aim. To study the association between family history and verified coronary heart disease (vCHD) in 25-64-year-old population of Novosibirsk City (data from cross-sectional epidemiological studies). Material and methods. As a part of the program WHO-MONICA, 7111 males and 5523 females from the nonorganized population of Novosibirsk City were examined. To identify independent risk factors for CHD, stepwise multiple logistic regression analysis was performed. Results. Prevalence of CHD in FH was 26.8% in males, and 37.7% in females. Independent factors, significantly increasing vCHD risk in males, were: advanced age (OR=1.10), atherogenicity index (AI) (OR=1.10), body mass index (OR=1.04), arterial hypertension (AH) (OR=1.63), CHD in FH (OR=1.71), AH in sisters (OR=1.63), AH in parents (OR=1.41); and in females: advanced age (OR=1.06), AI (OR=1.13), AH (OR=2.0), mother’s death from myocardial infarction (OR=2.28), father’s intermittent claudication (OR=4.13), diabetes mellitus in parents (OR=1.59). Conclusion. CHD in FH is an independent population risk factor for CHD. Due to its high prevalence and simple assessment, in can be used for identifying high-risk groups in need for primary prevention.</p></trans-abstract><kwd-group xml:lang="ru"><kwd>эпидемиология</kwd><kwd>ишемическая болезнь сердца</kwd><kwd>семейный анамнез</kwd><kwd>популяционные исследования</kwd></kwd-group><kwd-group xml:lang="en"><kwd>epidemiology</kwd><kwd>coronary heart disease</kwd><kwd>family history</kwd><kwd>population studies</kwd></kwd-group></article-meta></front><back><ref-list><title>References</title><ref id="cit1"><label>1</label><citation-alternatives><mixed-citation xml:lang="ru">Оганов Р.Г. Первичная профилактика ИБС. Москва «Медицина» 1990;158с.</mixed-citation><mixed-citation xml:lang="en">Оганов Р.Г. Первичная профилактика ИБС. Москва «Медицина» 1990;158с.</mixed-citation></citation-alternatives></ref><ref id="cit2"><label>2</label><citation-alternatives><mixed-citation xml:lang="ru">Никитин Ю.П., Малютина С.К., Симонова Г.И. и др. 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