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Lyubertsy Study of mortality in patients with acute myocardial infarction (LIS): the analysis of anamnestic predictors of in-hospital mortality

https://doi.org/10.15829/1728-8800-2012-1-45-48

Abstract

Aim. To identify the main anamnestic predictors of mortality in the acute phase of acute myocardial infarction (AMI).
Material and methods. The study included all patients admitted to Lyubertsy District hospitals and diagnosed with AMI (n=1133).
Results. Out of 1133 hospitalised patients, 172 died in the hospital; in-hospital lethality was 15,2%. Mean age of diseased patients was significantly higher than that in those survived. The risk of in-hospital death was significantly and independently associated with older age
(relative risk 1,07). After adjustment for age and sex, other independent predictors of in-hospital AMI death included diabetes mellitus (DM), low physical activity, and selected psychosocial factors.
Conclusion. The in-hospital lethality levels, observed in the LIS Study, were typical for the Russian Federation. The main anamnestic predictors of in-hospital death were low physical activity, DM, and psychosocial risk factors.

About the Authors

S. Yu. Martsevich
State Research Centre for Preventive Medicine; Evidence-Based Medicine Department, I.M. Sechenov First Moscow State Medical University, Moscow
Russian Federation


M. L. Ginsburg
Lyubertsy District Hospital No. 2, Moscow Region
Russian Federation


N. P. Kutishenko
State Research Centre for Preventive Medicine; Evidence-Based Medicine Department, I.M. Sechenov First Moscow State Medical University, Moscow
Russian Federation


A. D. Deev
State Research Centre for Preventive Medicine
Russian Federation


A. V. Fokina
Lyubertsy District Hospital No. 2, Moscow Region
Russian Federation


E. V. Daniels
Lyubertsy District Hospital No. 2, Moscow Region
Russian Federation


References

1. Руда М.Я., Зыско А.П. Инфаркт миокарда. М. 1977; 248 с.

2. Метелица В.И., Мазур Н.А. Эпидемиология и профилактика ишемической болезни сердца. М. 1976; 166 с.

3. Boersma E, Mercado N, Poldermans D, et al. Acute myocardial infarction. Lancet 2003; 361: 847-58.

4. Марцевич С.Ю., Гинзбург М.Л., Кутишенко Н.П. и др. Люберецкое исследование по изучению смертности больных, перенесших острый инфаркт миокарда. Первые результаты исследования “ЛИС”. Клиницист 2011; 1: 24-7.

5. Марцевич С.Ю., Гинзбург М.Л., Кутишенко Н.П. и др. Исследование ЛИС (Люберецкое исследование смертности больных, перенесших острый инфаркт миокарда): портрет заболевшего. Кардиоваскулярная терапия и профилактика 2011; 6: 89-93.

6. Ощепкова Е.В. Смертность населения от сердечно-сосудистых заболеваний в Российской Федерации и пути по ее снижению. Кардиология 2009; 2: 267-72.

7. Эрлих А.Д., Грацианский Н.А., участники исследования РЕКОРД. Лечение больных с острыми коронарными синдромами в стационарах, имеющих и не имеющих возможности выполнения инфазивных коронарных процедур. Кардиология 2010;7: 8-14.

8. Демографический ежегодник России. официальное издание. М. 2010; 525 с.

9. Hamm CW, Bassand J-P, Agewall S, et al. ESC Guidelines for the management of acute coronary syndromes in patients presenting without persistent ST-segment elevation. Eur Heart J doi:10.1093/eurheartj/ ehr236.

10. Teo K, Catellier D. Risk prediction after myocardial infarction in the elderly. JACC 2001; 38: 460-3.

11. Law M, Watt H, Wald N. The underlying risk of death after myocardial infarction in the absence of treatment. Arch Intern Med 2002; 162: 2405-10.

12. Mandelzweig L, Battler A, Boyko V. The second Euro Survey on acute coronary syndromes: characteristics, treatment and outcome of patients with ACS in Europe and the Mediterranean Basin in 2004. Eur Heart J 2006; 27: 2285-93.


Review

For citations:


Martsevich S.Yu., Ginsburg M.L., Kutishenko N.P., Deev A.D., Fokina A.V., Daniels E.V. Lyubertsy Study of mortality in patients with acute myocardial infarction (LIS): the analysis of anamnestic predictors of in-hospital mortality. Cardiovascular Therapy and Prevention. 2012;11(1):45-48. (In Russ.) https://doi.org/10.15829/1728-8800-2012-1-45-48

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ISSN 1728-8800 (Print)
ISSN 2619-0125 (Online)