Myocardial damage mechanisms in coronary artery bypass surgery (literature review)
Abstract
The paper discusses modern views on myocardial damage mechanisms in coronary artery bypass surgery (CABG). The publications reviewed include those on molecular basis and pathophysiological pathways in ischemia/ reperfusion syndrome, as well as on potential cardioprotective strategies.
About the Authors
Sh. Kh. Samadov
A.N. Bakoulev Research Centre for Cardiovascular Surgery, Russian Academy of Medical Sciences. Moscow
Russian Federation
Russian Federation
I. V. Koksheneva
A.N. Bakoulev Research Centre for Cardiovascular Surgery, Russian Academy of Medical Sciences. Moscow
Russian Federation
Russian Federation
References
1. Бокерия Л.А., Чичерин И.Н. Природа и клиническое значение “новых ишемических синдромов”. Москва. Изд. НЦ ССХ им.А.Н.Бакулева РАМН 2007.
2. Andrukhiv A, Costa AD, West IC, et al. Opening mitoKatp increases superoxide generation from complex 1 of the electron transport chain. Am J Physiol Heart Circ Physiol 2006; 29: H2067-74.
3. Anselmi A, Abbate A, Girola F, et al. Myocardial ischemia, stunning, inflammation, and apoptosis during cardiac surgery: a review of evidence. Eur J Cardiothorac Surg 2004; 25: 304-11.
4. Baines CP, Molkentin JD. STRESS signaling pathways that modulate cardiac myocyte apoptosis. J Mol Cell Cardiol 2005; 38(1): 47-62.
5. Birdi I, Angelini GD, Bryan AJ. Biochemical markers of myocardial injury during cardiac operations. Ann Thorac Surg 1997; 63: 879-84.
6. Canton M, Skyschally A, Menabo R, et al. Oxidative modification of tropomyosin and myocardial dysfunction following coronary microembolization. Eur Heart J 2006; 27: 875-81.
7. Carlucci F, Tabucchi A, Biagioli B, et al. Cardiac surgery: myocardial energy balance, antioxidant status and endothelial function after ischemia- reperfusion. Biomed Pharmacother 2002; 56: 483-91.
8. Dirksen MT, Laarman GJ, Simoons ML, et al. Reperfusion injury in humans: a review of clinical trials on reperfusion injury inhibitory strategies. Cardiovasc Res 2007: 343-55.
9. Galinanes M, James M, Codd V, et al. TNF- gene promoter polymorphism at nucleotide-308 and the inflammatory response and oxidative stress induced by cardiac surgery: role of heart failure and medical treatment. Eur J Cardiothorac Surg 2008; 34: 332-7.
10. Heusch Ph, Skyschally A, Leineweber K, et al. The interaction of coronary microembolization and ischemic preconditioning: A third window of cardioprotection through THF-alpha. Arch Med Sci 2007; 2: 83-92.
11. Joashi U, Tibby SM, Turner C, et al. Soluble Fas may be a proinflammatory marker after cardiopulmonary bypass in children. J Thorac Cardiovasc Surg 2002; 123: 137-44.
12. Levy JH, Tanaka KA. Inflamatory response to cardiopulmonary bypass. Ann Thorac Surg 2003; 75: S715-20.
13. Maulik N, Yoshida T. Oxidative stress developed during open heart surgery induces inflammation: reduction of apoptotic cell death by ebselen a glutathione peroxidase mimic. J Cardiovasc Pharmacol 2000; 36: 601-8.
14. Meyer K, Klocke RC, Schipke JD, et al. Ca2+ sensitizer superior to catecholamine during myocardial stunning? Eur J Card Thorac Surg 2008; 34: 326-31.
15. Moens AL, Claeys MJ, Timmermans JP, et al. Myocardial ischemia/ reperfusion- injury, a clinical view on a complex pathophysiological process. Int J Cardiol 2005; 100: 179-90.
16. Schmitt JP, Schroder J, Schunkert H, et al. Role of apoptosis in myocardial stunning after open heart surgery. Ann Thorac Surg 2002; 73: 1229-35.
17. Sharma M, Ganguly NK, Chaturvedi G, et al. Release of proinflammatory mediators during myocardial ischemia/reperfusion injury in coronary artery bypass graft surgery. Molec Cell Biochem 2003; 247: 23-30.
18. Sherman SK. Perioperative myocardial ischemia reperfusion injury. Anesthesiol Clin N Amer 2003; 21: 465-85.
19. Sodha NR, Clements RT, Feng J, et al. The effects of therapeutic sulfide on myocardial apoptosis in response to ischemiareperfusion injury. Eur J Cardiothorac Surg 2008; 33: 906-13.
20. Thielmann M, Dorge H, Martin C, et al. Myocardial dysfunction with coronary microembolization: signal transduction through a sequence of nitric jxide, tumor necrosis factor-alpha and sphingosine. Circ Res 2002: 90: 807-13.
21. Triana JF, Li XY, Jamaluddin U, et al. Postischemic myocardial “stunned myocardium” identification of major differences between the open-chest and the conscious dog and evaluation of the oxygen radical hypothesis in the conscious dog. Circ Res 1991; 69: 731-47.
22. Valen G. The basic biology of apoptosis and its implications for cardiac function and viability. Ann Thorac Surg 2003; 75: S656-60.
23. Wakaiyama H, Cowan DB, Toyoda Y, et al. Selective opening of mitochondrial ATP-Sensitive potassium channels during surgically induced myocardial ischemia decreases necrosis and apoptosis. Eur J Cardiothorac Surg 2002; 21: 424-33.
24. Wang M, Crisostomo PR, Markel TA, et al. Mechanisms of sex differences in TNFR2- mediated cardioprotection. Circulation 2008; 118: S38-45.
25. Wei GZ, Zhou JJ, Wang B, et al. Diastolic Ca2+ overload caused by Na+/Ca2+ exchanger during the first minutes of reperfusion results in continued myocardiol stunning. Eur J Pharmacol 2007; 572: 1-11.
26. Zeller CN, Wang Y, Markel TA, et al. Role of tumor necrosis factor receptor 1 in sex differences of stem cell mediated cardioprotection. Ann Thorac Surg 2009; 87: 812-9.
27. Zorc M, Vraspir-Porenta O, Zorc-Pleskovic R, et al. Apoptosis of myocites and proliferation markers as prognostic factors in end-stage dilated cardiomyopathy. Cardiovasc Pathol 2003; 12: 36-9.
Review
For citations:
Samadov Sh.Kh., Koksheneva I.V. Myocardial damage mechanisms in coronary artery bypass surgery (literature review). Cardiovascular Therapy and Prevention. 2010;9(8):75-80. (In Russ.)
Views:
537
Email this article 
