Heyde’s syndrome as a rare cause of gastrointestinal bleeding in aortic stenosis patients
https://doi.org/10.15829/1728-8800-2021-2503
Abstract
Heyde’s syndrome is one of the causes of gastrointestinal bleeding in patients with heart disease. It is characterized by the acquired destruction of high molecular weight multimers of von Willebrand factor due to high hydraulic shear stress on the aortic valve in severe stenosis, followed by gastrointestinal bleeding due to angiodysplasias. Management of such patients is a complex and relevant problem. The central method of treatment for Heyde’s syndrome is aortic valve replacement, which reduces the risk of recurrent gastrointestinal bleeding in more than 90% of patients.
About the Authors
D. V. Belov
Federal Center for Cardiovascular Surgery; South Ural State Medical University
Russian Federation
Russian Federation
Chelyabinsk
D. V. Garbuzenko
South Ural State Medical University
Russian Federation
Russian Federation
Chelyabinsk
O. P. Lukin
Federal Center for Cardiovascular Surgery; South Ural State Medical University
Russian Federation
Russian Federation
Chelyabinsk
S. S. Anufrieva
South Ural State Medical University
Russian Federation
Russian Federation
Chelyabinsk
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For citations:
Belov D.V., Garbuzenko D.V., Lukin O.P., Anufrieva S.S. Heyde’s syndrome as a rare cause of gastrointestinal bleeding in aortic stenosis patients. Cardiovascular Therapy and Prevention. 2021;20(1):2503. (In Russ.) https://doi.org/10.15829/1728-8800-2021-2503
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